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Stochastic Problems In Population Genetics
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Book Synopsis Stochastic Problems in Population Genetics by : T. Maruyama
Download or read book Stochastic Problems in Population Genetics written by T. Maruyama and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are" notes based on courses in Theoretical Population Genetics given at the University of Texas at Houston during the winter quarter, 1974, and at the University of Wisconsin during the fall semester, 1976. These notes explore problems of population genetics and evolution involving stochastic processes. Biological models and various mathematical techniques are discussed. Special emphasis is given to the diffusion method and an attempt is made to emphasize the underlying unity of various problems based on the Kolmogorov backward equation. A particular effort was made to make the subject accessible to biology students who are not familiar with stochastic processes. The references are not exhaustive but were chosen to provide a starting point for the reader interested in pursuing the subject further. Acknowledgement I would like to use this opportunity to express my thanks to Drs. J. F. Crow, M. Nei and W. J. Schull for their hospitality during my stays at their universities. I am indebted to Dr. M. Kimura for his continuous encouragement. My thanks also go to the small but resolute groups of.students, visitors and colleagues whose enthusiasm was a great source of encouragement. I am especially obliged to Dr. Martin Curie-Cohen and Dr. Crow for reading a large part eX the manuscript and making many valuable comments. Special gratitude is expressed to Miss Sumiko Imamiya for her patience and endurance and for her efficient preparation of the manuscript.
Book Synopsis Stochastic Processes in Physics and Engineering by : Sergio Albeverio
Download or read book Stochastic Processes in Physics and Engineering written by Sergio Albeverio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approach your problems from the right end It isn't that they can't see the solution. It is and begin with the answers. Then one day, that they can't see the problem. perhaps you will find the final question. O. K. Chesterton. The Scandal of Father 'The Hermit Qad in Crane Feathers' in R. Brown 'The point of a Pin'. van Gu!ik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, coding theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical programming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electrical engineering can use Stein spaces. And in addition to this there are such new emerging subdisciplines as "experimental mathematics", "CFD", "completely integrable systems", "chaos, synergetics and large-scale order", which are almost impossible to fit into the existing classification schemes. They draw upon widely different sections of mathematics.
Book Synopsis Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 by : Motoo Kimura
Download or read book Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 written by Motoo Kimura and published by Princeton University Press. This book was released on 2020-03-31 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.
Book Synopsis Theoretical Population Genetics by : J.S. Gale
Download or read book Theoretical Population Genetics written by J.S. Gale and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rise of the neutral theory of molecular evolution seems to have aroused a renewed interest in mathematical population genetics among biologists, who are primarily experimenters rather than theoreticians. This has encouraged me to set out the mathematics of the evolutionary process in a manner that, I hope, will be comprehensible to those with only a basic knowledge of calculus and matrix algebra. I must acknowledge from the start my great debt to my students. Equipped initially with rather limited mathematics, they have pursued the subject with much enthusiasm and success. This has enabled me to try a number of different approaches over the years. I was particularly grateful to Dr L. J. Eaves and Professor W. E. Nance for the opportunity to give a one-semester course at the Medical College of Virginia, and I would like to thank them, their colleagues and their students for the many kindnesses shown to me during my visit. I have concentrated almost entirely on stochastic topics, since these cause the greatest problems for non-mathematicians. The latter are particularly concerned with the range of validity of formulae. A sense of confidence in applying these formulae is, almost certainly, best gained by following their derivation. I have set out proofs in fair detail, since, in my experience, minor points of algebraic manipulation occasionally cause problems. To avoid loss of continuity, I have sometimes put material in notes at the end of chapters.
Book Synopsis Evolution and Selection of Quantitative Traits by : Bruce Walsh
Download or read book Evolution and Selection of Quantitative Traits written by Bruce Walsh and published by Oxford University Press. This book was released on 2018-06-21 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.
Book Synopsis Stochastic Problems in Population Genetics by :
Download or read book Stochastic Problems in Population Genetics written by and published by . This book was released on 1977 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Population Genetics by : John H. Gillespie
Download or read book Population Genetics written by John H. Gillespie and published by JHU Press. This book was released on 2004-08-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Book Synopsis An Introduction to Population Genetics Theory by : J.F. Crow
Download or read book An Introduction to Population Genetics Theory written by J.F. Crow and published by Scientific Publishers. This book was released on 2017-01-01 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text book, originally published in 1970, presents the field of population genetics, starting with elementary concepts and leading the reader well into the field. It is concerned mainly with population genetics in a strict sense and deals primarily with natural populations and less fully with the rather similar problems that arise in breading live stock and cul t i vat ed plans . The emphasis is on the behavior of genes and population attributes under natural selection where the most important measure is Darwinian fitness. This text is intended for graduatestudents and advanced undergraduates in genetics and population biology. This book steers a middle course between completely verbal biological arguments and the rigor of the mathematician. The first two-thirds of the book do not require advanced mathematical background. An ordinary knowledge of calculus will suffice. The latter parts of the book, which deal with population stochastically, use more advanced methods.
Book Synopsis Stochastic Models With Applications To Genetics, Cancers, Aids And Other Biomedical Systems by : Wai-yuan Tan
Download or read book Stochastic Models With Applications To Genetics, Cancers, Aids And Other Biomedical Systems written by Wai-yuan Tan and published by World Scientific. This book was released on 2002-02-26 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a systematic treatment of Markov chains, diffusion processes and state space models, as well as alternative approaches to Markov chains through stochastic difference equations and stochastic differential equations. It illustrates how these processes and approaches are applied to many problems in genetics, carcinogenesis, AIDS epidemiology and other biomedical systems.One feature of the book is that it describes the basic MCMC (Markov chain and Monte Carlo) procedures and illustrates how to use the Gibbs sampling method and the multilevel Gibbs sampling method to solve many problems in genetics, carcinogenesis, AIDS and other biomedical systems.As another feature, the book develops many state space models for many genetic problems, carcinogenesis, AIDS epidemiology and HIV pathogenesis. It shows in detail how to use the multilevel Gibbs sampling method to estimate (or predict) simultaneously the state variables and the unknown parameters in cancer chemotherapy, carcinogenesis, AIDS epidemiology and HIV pathogenesis. As a matter of fact, this book is the first to develop many state space models for many genetic problems, carcinogenesis and other biomedical problems.
Book Synopsis Stochastic Population Dynamics in Ecology and Conservation by : Russell Lande
Download or read book Stochastic Population Dynamics in Ecology and Conservation written by Russell Lande and published by OUP Oxford. This book was released on 2003 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Demographic and environmental stochasticity -- 2. Extinction dynamics -- 3. Age structure -- 4. Spatial structure -- 5. Population viability analysis -- 6. Sustainable harvesting -- 7. Species diversity -- 8. Community dynamics.
Book Synopsis Fast Variables in Stochastic Population Dynamics by : George William Albert Constable
Download or read book Fast Variables in Stochastic Population Dynamics written by George William Albert Constable and published by Springer. This book was released on 2015-07-25 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis two variants of the fast variable elimination method are developed. They are intuitive, simple to implement and give results which are in very good agreement with those found from numerical simulations. The relative simplicity of the techniques makes them ideal for applying to problems featuring demographic stochasticity, for experts and non-experts alike. Within the context of mathematical modelling, fast variable elimination is one of the central tools with which one can simplify a multivariate problem. When used in the context of of deterministic systems, the theory is quite standard, but when stochastic effects are present, it becomes less straightforward to apply. While the introductory and background chapters form an excellent primer to the theory of stochastic population dynamics, the techniques developed can be applied to systems exhibiting a separation of timescales in a variety of fields including population genetics, ecology and epidemiology.
Book Synopsis Population Genetics and Microevolutionary Theory by : Alan R. Templeton
Download or read book Population Genetics and Microevolutionary Theory written by Alan R. Templeton and published by John Wiley & Sons. This book was released on 2006-09-29 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Book Synopsis Memory Function Approaches to Stochastic Problems in Condensed Matter, Volume 62 by : Myron W. Evans
Download or read book Memory Function Approaches to Stochastic Problems in Condensed Matter, Volume 62 written by Myron W. Evans and published by John Wiley & Sons. This book was released on 2009-09-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international group of scholars presents a very important development in the theory of relaxation processes. For the first time, the basic equations of motion have been put into a form suitable for computation of a variety of observable phenomena in several different disciplines. This book begins with a description of the foundations of the memory function techniques, of the adiabatic elimination procedure and of the mathematics of continued fractions. It also covers depth relaxation phenomena in several areas of physics, chemistry, biology, electronic engineering, spectroscopy, computer simulation and astronomy.
Book Synopsis Mathematical Topics in Population Genetics by : Ken-ichi Kojima
Download or read book Mathematical Topics in Population Genetics written by Ken-ichi Kojima and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic method of analyzing particulate gene systems is the proba bilistic and statistical analyses. Mendel himself could not escape from an application of elementary probability analysis although he might have been unaware of this fact. Even Galtonian geneticists in the late 1800's and the early 1900's pursued problems of heredity by means of mathe matics and mathematical statistics. They failed to find the principles of heredity, but succeeded to establish an interdisciplinary area between mathematics and biology, which we call now Biometrics, Biometry, or Applied Statistics. A monumental work in the field of popUlation genetics was published by the late R. A. Fisher, who analyzed "the correlation among relatives" based on Mendelian gene theory (1918). This theoretical analysis over came "so-called blending inheritance" theory, and the orientation of Galtonian explanations for correlations among relatives for quantitative traits rapidly changed. We must not forget the experimental works of Johanson (1909) and Nilsson-Ehle (1909) which supported Mendelian gene theory. However, a large scale experiment for a test of segregation and linkage of Mendelian genes affecting quantitative traits was, prob ably for the first time, conducted by K. Mather and his associates and Panse in the 1940's.
Book Synopsis Population Genetics, Molecular Evolution, and the Neutral Theory by : Motoo Kimura
Download or read book Population Genetics, Molecular Evolution, and the Neutral Theory written by Motoo Kimura and published by University of Chicago Press. This book was released on 1994 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Book Synopsis Forward-Time Population Genetics Simulations by : Bo Peng
Download or read book Forward-Time Population Genetics Simulations written by Bo Peng and published by John Wiley & Sons. This book was released on 2012-01-25 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators. The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics. Forward-Time Population Genetics Simulations includes: An overview of currently available forward-time simulation methods, their advantages, and shortcomings An overview and evaluation of currently available software A simuPOP tutorial Applications in population genetics Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.
Book Synopsis Mathematical Population Genetics 1 by : Warren J. Ewens
Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
