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Stereoselective Syntheses Of Tetrahydropyrans
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Book Synopsis Stereoselective Syntheses of Tetrahydropyrans by : Kiyoun Lee
Download or read book Stereoselective Syntheses of Tetrahydropyrans written by Kiyoun Lee and published by Springer. This book was released on 2014-07-08 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and (±)diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology.
Book Synopsis Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans by : Nahla Ahmed Elsaid
Download or read book Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans written by Nahla Ahmed Elsaid and published by . This book was released on 2001 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings by : Megan Lesley Bolla
Download or read book Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings written by Megan Lesley Bolla and published by . This book was released on 2008 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Described in this dissertation are several methods developed for the stereoselective synthesis of tetrahydropyrans rings. Initially, an effort to expand the Mukaiyama Aldol-Prins cyclization reaction to disubstituted (E)-enol ethers was explored. The Mukaiyama-Michael cascade reaction was then discovered by a fortuitous result. Investigating this method provided an unexpected tetrahydropyran product containing 2,6-trans geometry, and is rationalized considering both steric and electronic effects. Finally, a two-step [4+2] inverse demand HDA annulation reaction and rearrangement was developed for the diastereoselective synthesis of 2,4,5,6- tetra-substituted tetrahydropyran rings.
Book Synopsis Towards the Rapid and Efficient Stereoselective Synthesis of Tetrahydropyrans by : Dennis Cooper
Download or read book Towards the Rapid and Efficient Stereoselective Synthesis of Tetrahydropyrans written by Dennis Cooper and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Stereoselective Synthesis of Substituted Tetrahydropyrans Using Acid-promoted Prins Cyclisations by : Gregory Dominic Parker
Download or read book The Stereoselective Synthesis of Substituted Tetrahydropyrans Using Acid-promoted Prins Cyclisations written by Gregory Dominic Parker and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis M-CPBA-mediated Stereoselective Synthesis of Sulfonyl Tetrahydropyrans by :
Download or read book M-CPBA-mediated Stereoselective Synthesis of Sulfonyl Tetrahydropyrans written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereoselective Synthesis by : Eckhard Ottow
Download or read book Stereoselective Synthesis written by Eckhard Ottow and published by . This book was released on 1993 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiechert's achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiechert's 65th birthday.
Book Synopsis The Stereoselective Synthesis of Oxygen and Nitrogen Heterocycles by : Dominique Stephanie Belanger
Download or read book The Stereoselective Synthesis of Oxygen and Nitrogen Heterocycles written by Dominique Stephanie Belanger and published by . This book was released on 2002 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereoselective Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives by Use of Asymmetric Horner-Wadsworth-Emmons and Ring Closure Reactions by : Lauri Vares
Download or read book Stereoselective Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives by Use of Asymmetric Horner-Wadsworth-Emmons and Ring Closure Reactions written by Lauri Vares and published by . This book was released on 2000 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Applications of Regioselective Intramolecular Oxidation by Dioxirane Generated in Situ by : Nga-Wai Chung
Download or read book Applications of Regioselective Intramolecular Oxidation by Dioxirane Generated in Situ written by Nga-Wai Chung and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereoselective Synthesis of Drugs and Natural Products by : Vasyl Andrushko
Download or read book Stereoselective Synthesis of Drugs and Natural Products written by Vasyl Andrushko and published by John Wiley & Sons. This book was released on 2013-08-16 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Book Synopsis The Stereospecific Synthesis of Tetrahydropyrans and Tetrahydrofurans by : Rhonda Carol Winstead
Download or read book The Stereospecific Synthesis of Tetrahydropyrans and Tetrahydrofurans written by Rhonda Carol Winstead and published by . This book was released on 1986 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis by : Jean Rodriguez
Download or read book Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis written by Jean Rodriguez and published by John Wiley & Sons. This book was released on 2015-04-08 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions
Book Synopsis Studies in Natural Products Chemistry by : Atta-ur-Rahman
Download or read book Studies in Natural Products Chemistry written by Atta-ur-Rahman and published by Elsevier Science. This book was released on 1996-05-15 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Volume 18 of this well-established series, Professor Atta-ur-Rahman again brings together the work of several of the world's leading authorities in organic chemistry. Their contributions demonstrate the rapid, ongoing development of this field by illustrating many of the latest advances in synthetic methods, total synthesis, structure determination, biosynthetic pathways, and biological activity. The opening chapter presents an overview of strategies for the synthesis of several classes of natural products with an emphasis on complex polycyclic systems. Subsequent chapters discuss the synthesis of specific classes of compounds, including morphine, polyketides, acetogenins, nonactic acid derivatives, complex spirocyclic ethers, ä-lactam and pyridone derivatives, inositol phosphates, sphingolipids, brassinosteroids, Hernandia lignans, and dimeric steroidal pyrazine alkaloids. Finally, the ever stronger links between chemistry and biology are reinforced by chapters on the origin and function of secondary metabolites, bioactive conformations of gastrin hormones, and immunochemistry.
Book Synopsis Synthesis of Saturated Oxygenated Heterocycles I by : Janine Cossy
Download or read book Synthesis of Saturated Oxygenated Heterocycles I written by Janine Cossy and published by Springer. This book was released on 2014-03-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
Book Synopsis Applications of Regioselective Intramolecular Oxidation by Dioxirane Generated in Situ by :
Download or read book Applications of Regioselective Intramolecular Oxidation by Dioxirane Generated in Situ written by and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic and Biosynthetic Approaches to Marine Natural Products by : Asunción Barbero
Download or read book Synthetic and Biosynthetic Approaches to Marine Natural Products written by Asunción Barbero and published by MDPI. This book was released on 2020-03-24 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine natural products containing a heterocyclic moiety in their structure are present in a wide variety of sponges, corals, algae, and fungi. Many of them show important biological activities such as cytotoxic properties against several cancer cell lines. Their challenging chemical structures have attracted the attention of many researchers who have developed various synthetic approaches. This Special Issue presents some examples of new synthetic or biosynthetic methodologies to access this type of marine natural drug.
