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Statistical Methods In Medical Research
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Book Synopsis Statistical Methods in Medical Research by : Charan Singh Rayat
Download or read book Statistical Methods in Medical Research written by Charan Singh Rayat and published by Springer. This book was released on 2018-08-23 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of statistical methods in detail with applications. It presents solutions to the needs of post-graduate medical students, doctors and basic medical scientists for statistical evaluation of data. In present era, dependency on softwares for statistical analysis is eroding the basic understanding of the statistical methods and their applications. As a result, there are very few basic medical scientists capable of analyzing their research data due to lack of knowledge and ability. This book has been written in systematic way supported by figures and tables for basic understanding of various terms, definitions, formulae and applications of statistical methods with solved examples and graphic presentation of data to create interest in this mathematical science.
Book Synopsis Statistical Methods in Medical Research by : P. Armitage
Download or read book Statistical Methods in Medical Research written by P. Armitage and published by Blackwell Scientific Publications Limited. This book was released on 1971-01-01 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Essential Statistical Methods for Medical Statistics by : J. Philip Miller
Download or read book Essential Statistical Methods for Medical Statistics written by J. Philip Miller and published by Elsevier. This book was released on 2010-11-08 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. · Contributors are internationally renowned experts in their respective areas · Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research · Methods for assessing Biomarkers, analysis of competing risks · Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs · Structural equations modelling and longitudinal data analysis
Book Synopsis Common Statistical Methods for Clinical Research with SAS Examples, Third Edition by : Glenn Walker
Download or read book Common Statistical Methods for Clinical Research with SAS Examples, Third Edition written by Glenn Walker and published by SAS Institute. This book was released on 2010-02-15 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glenn Walker and Jack Shostak's Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is a thoroughly updated edition of the popular introductory statistics book for clinical researchers. This new edition has been extensively updated to include the use of ODS graphics in numerous examples as well as a new emphasis on PROC MIXED. Straightforward and easy to use as either a text or a reference, the book is full of practical examples from clinical research to illustrate both statistical and SAS methodology. Each example is worked out completely, step by step, from the raw data. Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is an applications book with minimal theory. Each section begins with an overview helpful to nonstatisticians and then drills down into details that will be valuable to statistical analysts and programmers. Further details, as well as bonus information and a guide to further reading, are presented in the extensive appendices. This text is a one-source guide for statisticians that documents the use of the tests used most often in clinical research, with assumptions, details, and some tricks--all in one place. This book is part of the SAS Press program.
Book Synopsis Statistical Methods in Healthcare by : Frederick W. Faltin
Download or read book Statistical Methods in Healthcare written by Frederick W. Faltin and published by John Wiley & Sons. This book was released on 2012-07-24 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Methods in Healthcare In recent years the number of innovative medicinal products and devices submitted and approved by regulatory bodies has declined dramatically. The medical product development process is no longer able to keep pace with increasing technologies, science and innovations and the goal is to develop new scientific and technical tools and to make product development processes more efficient and effective. Statistical Methods in Healthcare focuses on the application of statistical methodologies to evaluate promising alternatives and to optimize the performance and demonstrate the effectiveness of those that warrant pursuit is critical to success. Statistical methods used in planning, delivering and monitoring health care, as well as selected statistical aspects of the development and/or production of pharmaceuticals and medical devices are also addressed. With a focus on finding solutions to these challenges, this book: Provides a comprehensive, in-depth treatment of statistical methods in healthcare, along with a reference source for practitioners and specialists in health care and drug development. Offers a broad coverage of standards and established methods through leading edge techniques. Uses an integrated case study based approach, with focus on applications. Looks at the use of analytical and monitoring schemes to evaluate therapeutic performance. Features the application of modern quality management systems to clinical practice, and to pharmaceutical development and production processes. Addresses the use of modern statistical methods such as Adaptive Design, Seamless Design, Data Mining, Bayesian networks and Bootstrapping that can be applied to support the challenging new vision. Practitioners in healthcare-related professions, ranging from clinical trials to care delivery to medical device design, as well as statistical researchers in the field, will benefit from this book.
Book Synopsis Introduction to Statistical Methods for Clinical Trials by : Thomas D. Cook
Download or read book Introduction to Statistical Methods for Clinical Trials written by Thomas D. Cook and published by CRC Press. This book was released on 2007-11-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.
Book Synopsis Practical Statistics for Medical Research by : Douglas G. Altman
Download or read book Practical Statistics for Medical Research written by Douglas G. Altman and published by CRC Press. This book was released on 1990-11-22 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on twenty years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. Using real data and including dozens of interesting data sets, this bestselling text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research.
Book Synopsis Brief Guidelines for Methods and Statistics in Medical Research by : Jamalludin Bin Ab Rahman
Download or read book Brief Guidelines for Methods and Statistics in Medical Research written by Jamalludin Bin Ab Rahman and published by Springer. This book was released on 2015-10-14 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a practical guide to methods and statistics in medical research. It includes step-by-step instructions on using SPSS software for statistical analysis, as well as relevant examples to help those readers who are new to research in health and medical fields. Simple texts and diagrams are provided to help explain the concepts covered, and print screens for the statistical steps and the SPSS outputs are provided, together with interpretations and examples of how to report on findings. Brief Guidelines for Methods and Statistics in Medical Research offers a valuable quick reference guide for healthcare students and practitioners conducting research in health related fields, written in an accessible style.
Book Synopsis Small Clinical Trials by : Institute of Medicine
Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Book Synopsis Modern Statistical Methods for Health Research by : Yichuan Zhao
Download or read book Modern Statistical Methods for Health Research written by Yichuan Zhao and published by Springer. This book was released on 2022-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together the voices of leading experts in the frontiers of biostatistics, biomedicine, and the health sciences to discuss the statistical procedures, useful methods, and novel applications in biostatistics research. It also includes discussions of potential future directions of biomedicine and new statistical developments for health research, with the intent of stimulating research and fostering the interactions of scholars across health research related disciplines. Topics covered include: Health data analysis and applications to EHR data Clinical trials, FDR, and applications in health science Big network analytics and its applications in GWAS Survival analysis and functional data analysis Graphical modelling in genomic studies The book will be valuable to data scientists and statisticians who are working in biomedicine and health, other practitioners in the health sciences, and graduate students and researchers in biostatistics and health.
Book Synopsis Statistical Methods in Diagnostic Medicine by : Xiao-Hua Zhou
Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in thefield, serving as a much-needed guide for both clinicians andadvanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests inmedical research In recent years, a considerable amount of research has focusedon evolving methods for designing and analyzing diagnostic accuracystudies. Statistical Methods in Diagnostic Medicine, Second Editioncontinues to provide a comprehensive approach to the topic, guidingreaders through the necessary practices for understanding thesestudies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy andstudy design, the authors successfully define various measures ofdiagnostic accuracy, describe strategies for designing diagnosticaccuracy studies, and present key statistical methods forestimating and comparing test accuracy. Topics new to the SecondEdition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values andsample size calculations Correcting techniques for verification and imperfect standardbiases Sample size calculation for multiple reader studies when pilotdata are available Updated meta-analysis methods, now incorporating randomeffects Three case studies thoroughly showcase some of the questions andstatistical issues that arise in diagnostic medicine, with allassociated data provided in detailed appendices. A related web sitefeatures Fortran, SAS®, and R software packages so thatreaders can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is anexcellent supplement for biostatistics courses at the graduatelevel. It also serves as a valuable reference for clinicians andresearchers working in the fields of medicine, epidemiology, andbiostatistics.
Book Synopsis Statistical Methods in Medical Research by : Peter Armitage
Download or read book Statistical Methods in Medical Research written by Peter Armitage and published by John Wiley & Sons. This book was released on 2013-07-01 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explanation and implementation of statistical methods for themedical researcher or statistician remains an integral part ofmodern medical research. This book explains the use of experimentaland analytical biostatistics systems. Its accessible style allowsit to be used by the non-mathematician as a fundamental componentof successful research. Since the third edition, there have been many developments instatistical techniques. The fourth edition provides the medicalstatistician with an accessible guide to these techniques and toreflect the extent of their usage in medical research. The new edition takes a much more comprehensive approach to itssubject. There has been a radical reorganization of the text toimprove the continuity and cohesion of the presentation and toextend the scope by covering many new ideas now being introducedinto the analysis of medical research data. The authors have triedto maintain the modest level of mathematical exposition thatcharacterized the earlier editions, essentially confining themathematics to the statement of algebraic formulae rather thanpursuing mathematical proofs. Received the Highly Commended Certificate in the PublicHealth Category of the 2002 BMA BooksCompetition.
Book Synopsis Statistical Methods for Health Care Research by : Barbara Hazard Munro
Download or read book Statistical Methods for Health Care Research written by Barbara Hazard Munro and published by Lippincott Raven. This book was released on 2001 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This singular text provides nursing students as well as students in all other health-related disciplines with a solid foundation for understanding data and specific statistical techniques. In this newest edition, outstanding faculty contributors focus on the most current and most frequently used statistical methods in today's health care literature, covering essential material for a variety of program levels including in-depth courses beyond the basic statistics course. Well-organized and clear text discussions and great learning tools help you cut through the complexities and fully comprehend the concepts of this often intimidating area of study. Book jacket.
Book Synopsis Statistics in Medicine by : Robert H. Riffenburgh
Download or read book Statistics in Medicine written by Robert H. Riffenburgh and published by Academic Press. This book was released on 2006 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine deals with treatments that work often but not always, so treatment success must be based on probability. Statistical methods lift medical research from the anecdotal to measured levels of probability. This book presents the common statistical methods used in 90% of medical research, along with the underlying basics, in two parts: a textbook section for use by students in health care training programs, e.g., medical schools or residency training, and a reference section for use by practicing clinicians in reading medical literature and performing their own research. The book does not require a significant level of mathematical knowledge and couches the methods in multiple examples drawn from clinical medicine, giving it applicable context. Easy-to-follow format incorporates medical examples, step-by-step methods, and check yourself exercises Two-part design features course material and a professional reference section Chapter summaries provide a review of formulas, method algorithms, and check lists Companion site links to statistical databases that can be downloaded and used to perform the exercises from the book and practice statistical methods New in this Edition: New chapters on: multifactor tests on means of continuous data, equivalence testing, and advanced methods New topics include: trial randomization, treatment ethics in medical research, imputation of missing data, and making evidence-based medical decisions Updated database coverage and additional exercises Expanded coverage of numbers needed to treat and to benefit, and regression analysis including stepwise regression and Cox regression Thorough discussion on required sample size
Book Synopsis Tutorials in Biostatistics, Statistical Methods in Clinical Studies by : Ralph B. D'Agostino
Download or read book Tutorials in Biostatistics, Statistical Methods in Clinical Studies written by Ralph B. D'Agostino and published by John Wiley & Sons. This book was released on 2005-09-27 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Tutorials in Biostatistics have become a very popular feature of the prestigious Wiley journal, Statistics in Medicine (SIM). The introductory style and practical focus make them accessible to a wide audience including medical practitioners with limited statistical knowledge. This book represents the first of two volumes presenting the best tutorials published in SIM, focusing on statistical methods in clinical studies. Topics include the design and analysis of clinical trials, epidemiology, survival analysis, and data monitoring. Each tutorial is focused on a medical problem, has been fully peer-reviewed and edited, and is authored by leading researchers in biostatistics. Many articles include an appendix on the latest developments since publication in the journal and additional references. This will appeal to statisticians working in medical research, as well as statistically-minded clinicians, biologists, epidemiologists and geneticists. It will also appeal to graduate students of biostatistics.
Book Synopsis Design of Experiments and Advanced Statistical Techniques in Clinical Research by : Basavarajaiah D. M.
Download or read book Design of Experiments and Advanced Statistical Techniques in Clinical Research written by Basavarajaiah D. M. and published by Springer Nature. This book was released on 2020-11-05 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope.
Book Synopsis Statistical Remedies for Medical Researchers by : Peter F. Thall
Download or read book Statistical Remedies for Medical Researchers written by Peter F. Thall and published by Springer Nature. This book was released on 2020-03-12 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious. For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect inferences being made. The technical level is kept to a minimum to make the book accessible to non-statisticians. At the same time, since many of the examples describe methods used routinely by medical statisticians with formal statistical training, the book appeals to a broad readership in the medical research community.