Statistical And Methodological Aspects Of Oral Health Research

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Statistical and Methodological Aspects of Oral Health Research

Author : Emmanuel Lesaffre
Publisher : John Wiley & Sons
ISBN 13 : 9780470744123
Total Pages : 408 pages
Book Rating : 4.7/5 (441 download)

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Book Synopsis Statistical and Methodological Aspects of Oral Health Research by : Emmanuel Lesaffre

Download or read book Statistical and Methodological Aspects of Oral Health Research written by Emmanuel Lesaffre and published by John Wiley & Sons. This book was released on 2009-03-09 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical and Methodological Aspects of Oral Health Research provides oral health researchers with an overview of the methodological aspects that are important in planning, conducting and analyzing their research projects whilst also providing biostatisticians with an idea of the statistical problems that arise when tackling oral health research questions. This collection presents critical reflections on oral health research and offers advice on practical aspects of setting up research whilst introducing the reader to basic as well as advanced statistical methodology. Features: An introduction to research methodology and an exposition of the state of the art. A variety of examples from oral health research. Contributions from well-known oral health researchers, epidemiologists and biostatisticians, all of whom have rich experience in this area. Recent developments in statistical methodology prompted by a variety of dental applications. Presenting both an introduction to research methodology and an exposition of the latest advances in oral health research, this book will appeal both beginning and experienced oral health researchers as well as biostatisticians and epidemiologists.

Research Methods for Oral Health Professionals

Author : Michele Leonardi Darby
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Methods for Oral Health Professionals by : Michele Leonardi Darby

Download or read book Research Methods for Oral Health Professionals written by Michele Leonardi Darby and published by . This book was released on 1980 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Research in Oral Health

Author : William V. Giannobile
Publisher : John Wiley & Sons
ISBN 13 : 0813820553
Total Pages : 394 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Clinical Research in Oral Health by : William V. Giannobile

Download or read book Clinical Research in Oral Health written by William V. Giannobile and published by John Wiley & Sons. This book was released on 2009-12-09 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

Burt and Eklund’s Dentistry, Dental Practice, and the Community - E-Book

Author : Amer Assoc of Public Health Dentistry
Publisher : Elsevier Health Sciences
ISBN 13 : 0323554857
Total Pages : 354 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Burt and Eklund’s Dentistry, Dental Practice, and the Community - E-Book by : Amer Assoc of Public Health Dentistry

Download or read book Burt and Eklund’s Dentistry, Dental Practice, and the Community - E-Book written by Amer Assoc of Public Health Dentistry and published by Elsevier Health Sciences. This book was released on 2020-03-22 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn about the challenges, current trends, and the positive role that you can play in improving the dental health of the community. Completely revised and updated by members of the American Association of Public Health Dentistry, Burt and Eklund's Dentistry, Dental Practice, and the Community, 7th Edition presents dentistry and dental practice against the ever-changing backdrop of economic, technological, and demographic trends, as well as the distribution of the oral diseases that dental professionals treat and prevent. Readers will learn the latest techniques of research and measurement, and how oral disease may be limited through control and prevention. This updated text also addresses the new educational competencies for predoctoral/ post-doctoral dental students and dental hygiene students with updated and new content on cultural competency, oral health literacy, social responsibility, motivational interviewing, and oral systemic associations. All in all, this text takes a comprehensive look at the social context of dental care and the difference you can make in improving the health of the community you serve. Logical four-part organization divides content into dentistry and the community; dental care delivery; methods and measurement of oral diseases and conditions; and health promotion and prevention of oral diseases. A focus on need-to-know content emphasizes the important core information while providing comprehensive coverage of dental public health. Comprehensive analysis of dentistry’s social and professional role examines issues such as epidemiology of oral diseases, prevention, and the provision of care. Evidence-based recommendations reflect the latest literature on today’s public health issues. Illustrations, tables, and graphics illustrate the key material and visually enhance discussions. NEW! Completely revised and updated content looks at populations oral health and dental care as well as how it fits into a changing world. NEW! Coverage of new educational competencies provides predoctoral/ post-doctoral dental students and dental hygiene students with updated and new content on cultural competency, oral health literacy, social responsibility, motivational interviewing, and oral systemic associations. NEW! New chapters cover the applications of epidemiology and biostatistics in dental public health, oral health as it related to quality of life, oral health education, health literacy, social determinants of health and health disparities, and delivery of oral healthcare in Canada. NEW! Newly revised competencies for the Dental Public Health specialty are incorporated throughout the book.

Oral Health Surveys

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241548649
Total Pages : 136 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Oral Health Surveys by : World Health Organization

Download or read book Oral Health Surveys written by World Health Organization and published by World Health Organization. This book was released on 2013 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Basic oral health surveys provide a sound basis for assessing the current oral health status of a population and its future needs for oral health care. The World Health Organization (WHO) has a long tradition of epidemiological survey methodology, which includes a description of the diagnostic criteria that can be readily understood and applied in public health programmes worldwide. The WHO manual Oral Health Surveys - Basic Methods has encouraged countries to conduct standardized oral health surveys that are comparable internationally. The WHO Global Oral Health Data Bank collates the data gathered through country surveys on the burden of oral disease and WHO recommended statistical analysis on key indicator age groups of children and adults. This manual aims to encourage national oral health survey planners to standardize measurements of oral diseases and conditions that are important for planning and evaluation of oral health programmes, as well as to ensure the comparability of data collected in a wide range of environments. It does this by applying the WHO global approach to chronic disease surveillance to an operational model for integration of oral health into chronic disease surveillance systems."--Publisher's description.

Biostatistics for Oral Healthcare

Author : Jay S. Kim
Publisher : John Wiley & Sons
ISBN 13 : 0470388277
Total Pages : 344 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Biostatistics for Oral Healthcare by : Jay S. Kim

Download or read book Biostatistics for Oral Healthcare written by Jay S. Kim and published by John Wiley & Sons. This book was released on 2008-06-02 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biostatistics for Oral Healthcare offers students, practitioners and instructors alike a comprehensive guide to mastering biostatistics and their application to oral healthcare. Drawing on situations and methods from dentistry and oral healthcare, this book provides a thorough treatment of statistical concepts in order to promote in-depth and correct comprehension, supported throughout by technical discussion and a multitude of practical examples.

Statistical Methods for Trend Detection and Analysis in the Environmental Sciences

Author : Richard Chandler
Publisher : John Wiley & Sons
ISBN 13 : 111999196X
Total Pages : 348 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Statistical Methods for Trend Detection and Analysis in the Environmental Sciences by : Richard Chandler

Download or read book Statistical Methods for Trend Detection and Analysis in the Environmental Sciences written by Richard Chandler and published by John Wiley & Sons. This book was released on 2011-03-25 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to understand and quantify change is fundamental throughout the environmental sciences. This might involve describing past variation, understanding the mechanisms underlying observed changes, making projections of possible future change, or monitoring the effect of intervening in some environmental system. This book provides an overview of modern statistical techniques that may be relevant in problems of this nature. Practitioners studying environmental change will be familiar with many classical statistical procedures for the detection and estimation of trends. However, the ever increasing capacity to collect and process vast amounts of environmental information has led to growing awareness that such procedures are limited in the insights that they can deliver. At the same time, significant developments in statistical methodology have often been widely dispersed in the statistical literature and have therefore received limited exposure in the environmental science community. This book aims to provide a thorough but accessible review of these developments. It is split into two parts: the first provides an introduction to this area and the second part presents a collection of case studies illustrating the practical application of modern statistical approaches to the analysis of trends in real studies. Key Features: Presents a thorough introduction to the practical application and methodology of trend analysis in environmental science. Explores non-parametric estimation and testing as well as parametric techniques. Methods are illustrated using case studies from a variety of environmental application areas. Looks at trends in all aspects of a process including mean, percentiles and extremes. Supported by an accompanying website featuring datasets and R code. The book is designed to be accessible to readers with some basic statistical training, but also contains sufficient detail to serve as a reference for practising statisticians. It will therefore be of use to postgraduate students and researchers both in the environmental sciences and in statistics.

Statistical Methods for Evaluating Safety in Medical Product Development

Author : A. Lawrence Gould
Publisher : John Wiley & Sons
ISBN 13 : 1118763106
Total Pages : 392 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Statistical Methods for Evaluating Safety in Medical Product Development by : A. Lawrence Gould

Download or read book Statistical Methods for Evaluating Safety in Medical Product Development written by A. Lawrence Gould and published by John Wiley & Sons. This book was released on 2014-12-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code

Introduction to Probability and Statistics for Ecosystem Managers

Author : Timothy C. Haas
Publisher : John Wiley & Sons
ISBN 13 : 1118636236
Total Pages : 271 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Introduction to Probability and Statistics for Ecosystem Managers by : Timothy C. Haas

Download or read book Introduction to Probability and Statistics for Ecosystem Managers written by Timothy C. Haas and published by John Wiley & Sons. This book was released on 2013-05-21 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores computer-intensive probability and statistics for ecosystem management decision making Simulation is an accessible way to explain probability and stochastic model behavior to beginners. This book introduces probability and statistics to future and practicing ecosystem managers by providing a comprehensive treatment of these two areas. The author presents a self-contained introduction for individuals involved in monitoring, assessing, and managing ecosystems and features intuitive, simulation-based explanations of probabilistic and statistical concepts. Mathematical programming details are provided for estimating ecosystem model parameters with Minimum Distance, a robust and computer-intensive method. The majority of examples illustrate how probability and statistics can be applied to ecosystem management challenges. There are over 50 exercises – making this book suitable for a lecture course in a natural resource and/or wildlife management department, or as the main text in a program of self-study. Key features: Reviews different approaches to wildlife and ecosystem management and inference. Uses simulation as an accessible way to explain probability and stochastic model behavior to beginners. Covers material from basic probability through to hierarchical Bayesian models and spatial/ spatio-temporal statistical inference. Provides detailed instructions for using R, along with complete R programs to recreate the output of the many examples presented. Provides an introduction to Geographic Information Systems (GIS) along with examples from Quantum GIS, a free GIS software package. A companion website featuring all R code and data used throughout the book. Solutions to all exercises are presented along with an online intelligent tutoring system that supports readers who are using the book for self-study.

Modern Industrial Statistics

Author : Shelemyahu Zacks
Publisher : John Wiley & Sons
ISBN 13 : 1118763696
Total Pages : 740 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Modern Industrial Statistics by : Shelemyahu Zacks

Download or read book Modern Industrial Statistics written by Shelemyahu Zacks and published by John Wiley & Sons. This book was released on 2013-12-16 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and updated, this book combines a theoretical background with examples and references to R, MINITAB and JMP, enabling practitioners to find state-of-the-art material on both foundation and implementation tools to support their work. Topics addressed include computer-intensive data analysis, acceptance sampling, univariate and multivariate statistical process control, design of experiments, quality by design, and reliability using classical and Bayesian methods. The book can be used for workshops or courses on acceptance sampling, statistical process control, design of experiments, and reliability. Graduate and post-graduate students in the areas of statistical quality and engineering, as well as industrial statisticians, researchers and practitioners in these fields will all benefit from the comprehensive combination of theoretical and practical information provided in this single volume. Modern Industrial Statistics: With applications in R, MINITAB and JMP: Combines a practical approach with theoretical foundations and computational support. Provides examples in R using a dedicated package called MISTAT, and also refers to MINITAB and JMP. Includes exercises at the end of each chapter to aid learning and test knowledge. Provides over 40 data sets representing real-life case studies. Is complemented by a comprehensive website providing an introduction to R, and installations of JMP scripts and MINITAB macros, including effective tutorials with introductory material: www.wiley.com/go/modern_industrial_statistics.

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation

Author : Stephen J. Walters
Publisher : John Wiley & Sons
ISBN 13 : 9780470871911
Total Pages : 380 pages
Book Rating : 4.8/5 (719 download)

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Book Synopsis Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation by : Stephen J. Walters

Download or read book Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation written by Stephen J. Walters and published by John Wiley & Sons. This book was released on 2009-09-10 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential, up-to-date guide to the design of studies and selection of the correct QoL instruments for observational studies and clinical trials. Quality of Life (QoL) outcomes or Person/Patient Reported Outcome Measures (PROMs) are now frequently being used in randomised controlled trials (RCTs) and observational studies. This book provides a practical guide to the design, analysis and interpretation of studies that use such outcomes. QoL outcomes tend to generate data with discrete, bounded and skewed distributions. Many investigators are concerned about the appropriateness of using standard statistical methods to analyse QoL data and want guidance on what methods to use. QoL outcomes are frequently used in cross-sectional surveys and non-randomised health-care evaluations. Provides a user-friendly guide to the design and analysis of clinical trials and observational studies in relation to QoL outcomes. Discusses the problems caused by QoL outcomes and presents intervention options to help tackle them. Guides the reader step-by-step through the selection of appropriate QoLs. Features exercises and solutions and a supporting website providing downloadable data files. Illustrated throughout with examples and case studies drawn from the author’s experience, this book offers statisticians and clinicians guidance on choosing between the numerous available QoL instruments.

Statistical Monitoring of Complex Multivatiate Processes

Author : Uwe Kruger
Publisher : John Wiley & Sons
ISBN 13 : 1118381262
Total Pages : 472 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Statistical Monitoring of Complex Multivatiate Processes by : Uwe Kruger

Download or read book Statistical Monitoring of Complex Multivatiate Processes written by Uwe Kruger and published by John Wiley & Sons. This book was released on 2012-08-06 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development and application of multivariate statisticaltechniques in process monitoring has gained substantial interestover the past two decades in academia and industry alike. Initially developed for monitoring and fault diagnosis in complexsystems, such techniques have been refined and applied in variousengineering areas, for example mechanical and manufacturing,chemical, electrical and electronic, and power engineering. The recipe for the tremendous interest in multivariate statisticaltechniques lies in its simplicity and adaptability for developingmonitoring applications. In contrast, competitive model,signal or knowledge based techniques showed their potential onlywhenever cost-benefit economics have justified the required effortin developing applications. Statistical Monitoring of Complex Multivariate Processespresents recent advances in statistics based process monitoring,explaining how these processes can now be used in areas such asmechanical and manufacturing engineering for example, in additionto the traditional chemical industry. This book: Contains a detailed theoretical background of the componenttechnology. Brings together a large body of work to address thefield’s drawbacks, and develops methods for theirimprovement. Details cross-disciplinary utilization, exemplified by examplesin chemical, mechanical and manufacturing engineering. Presents real life industrial applications, outliningdeficiencies in the methodology and how to address them. Includes numerous examples, tutorial questions and homeworkassignments in the form of individual and team-based projects, toenhance the learning experience. Features a supplementary website including Matlab algorithmsand data sets. This book provides a timely reference text to the rapidlyevolving area of multivariate statistical analysis for academics,advanced level students, and practitioners alike.

Binary Data Analysis of Randomized Clinical Trials with Noncompliance

Author : Kung-Jong Lui
Publisher : John Wiley & Sons
ISBN 13 : 1119993903
Total Pages : 217 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Binary Data Analysis of Randomized Clinical Trials with Noncompliance by : Kung-Jong Lui

Download or read book Binary Data Analysis of Randomized Clinical Trials with Noncompliance written by Kung-Jong Lui and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is quite common in a randomized clinical trial (RCT) to encounter patients who do not comply with their assigned treatment. Since noncompliance often occurs non-randomly, the commonly-used approaches, including both the as-treated (AT) and as-protocol (AP) analysis, and the intent-to-treat (ITT) (or as-randomized) analysis, are all well known to possibly produce a biased inference of the treatment efficacy. This book provides a systematic and organized approach to analyzing data for RCTs with noncompliance under the most frequently-encountered situations. These include parallel sampling, stratified sampling, cluster sampling, parallel sampling with subsequent missing outcomes, and a series of dependent Bernoulli sampling for repeated measurements. The author provides a comprehensive approach by using contingency tables to illustrate the latent probability structure of observed data. Using real-life examples, computer-simulated data and exercises in each chapter, the book illustrates the underlying theory in an accessible, and easy to understand way. Key features: Consort-flow diagrams and numerical examples are used to illustrate the bias of commonly used approaches, such as, AT analysis, AP analysis and ITT analysis for a RCT with noncompliance. Real-life examples are used throughout the book to explain the practical usefulness of test procedures and estimators. Each chapter is self-contained, allowing the book to be used as a reference source. Includes SAS programs which can be easily modified in calculating the required sample size. Biostatisticians, clinicians, researchers and data analysts working in pharmaceutical industries will benefit from this book. This text can also be used as supplemental material for a course focusing on clinical statistics or experimental trials in epidemiology, psychology and sociology.

Multiple Imputation and its Application

Author : James Carpenter
Publisher : John Wiley & Sons
ISBN 13 : 111844261X
Total Pages : 308 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Multiple Imputation and its Application by : James Carpenter

Download or read book Multiple Imputation and its Application written by James Carpenter and published by John Wiley & Sons. This book was released on 2012-12-19 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to analysing partially observed data. Collecting, analysing and drawing inferences from data is central to research in the medical and social sciences. Unfortunately, it is rarely possible to collect all the intended data. The literature on inference from the resulting incomplete data is now huge, and continues to grow both as methods are developed for large and complex data structures, and as increasing computer power and suitable software enable researchers to apply these methods. This book focuses on a particular statistical method for analysing and drawing inferences from incomplete data, called Multiple Imputation (MI). MI is attractive because it is both practical and widely applicable. The authors aim is to clarify the issues raised by missing data, describing the rationale for MI, the relationship between the various imputation models and associated algorithms and its application to increasingly complex data structures. Multiple Imputation and its Application: Discusses the issues raised by the analysis of partially observed data, and the assumptions on which analyses rest. Presents a practical guide to the issues to consider when analysing incomplete data from both observational studies and randomized trials. Provides a detailed discussion of the practical use of MI with real-world examples drawn from medical and social statistics. Explores handling non-linear relationships and interactions with multiple imputation, survival analysis, multilevel multiple imputation, sensitivity analysis via multiple imputation, using non-response weights with multiple imputation and doubly robust multiple imputation. Multiple Imputation and its Application is aimed at quantitative researchers and students in the medical and social sciences with the aim of clarifying the issues raised by the analysis of incomplete data data, outlining the rationale for MI and describing how to consider and address the issues that arise in its application.

An Introduction to Clinical Research for Health and Social Care Professionals

Author : Ario Santini
Publisher : AuthorHouse
ISBN 13 : 166559750X
Total Pages : 319 pages
Book Rating : 4.6/5 (655 download)

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Book Synopsis An Introduction to Clinical Research for Health and Social Care Professionals by : Ario Santini

Download or read book An Introduction to Clinical Research for Health and Social Care Professionals written by Ario Santini and published by AuthorHouse. This book was released on 2022-05-22 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing emphasis on evidence-based practice, there is a need for all health and social care professionals to understand the principles of general and clinical research. In the United Kingdom and several other countries, this had led to a proliferation of advanced programs, including for those seeking doctorate degrees. In this book, the editors introduce readers to the principles and practice of clinical research. Eighteen chapters and three appendices provide guidance on the different stages of a research project, from inception to the dissemination of results. Topics include: • steps to engage in practice-based research; • ethical questions surrounding research; • sources of funding; • collecting and collating data. Contributing authors emphasize the need to critically appraise literature before carrying out a research project. They also explain the stages of a research project and share insights on where to go for more information. The book includes an index, a glossary, and charts and figures to promote learning. Discussion questions reinforce critical material.

Maximum Likelihood Estimation and Inference

Author : Russell B. Millar
Publisher : John Wiley & Sons
ISBN 13 : 1119977711
Total Pages : 286 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Maximum Likelihood Estimation and Inference by : Russell B. Millar

Download or read book Maximum Likelihood Estimation and Inference written by Russell B. Millar and published by John Wiley & Sons. This book was released on 2011-07-26 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a fresh look at the popular and well-established method of maximum likelihood for statistical estimation and inference. It begins with an intuitive introduction to the concepts and background of likelihood, and moves through to the latest developments in maximum likelihood methodology, including general latent variable models and new material for the practical implementation of integrated likelihood using the free ADMB software. Fundamental issues of statistical inference are also examined, with a presentation of some of the philosophical debates underlying the choice of statistical paradigm. Key features: Provides an accessible introduction to pragmatic maximum likelihood modelling. Covers more advanced topics, including general forms of latent variable models (including non-linear and non-normal mixed-effects and state-space models) and the use of maximum likelihood variants, such as estimating equations, conditional likelihood, restricted likelihood and integrated likelihood. Adopts a practical approach, with a focus on providing the relevant tools required by researchers and practitioners who collect and analyze real data. Presents numerous examples and case studies across a wide range of applications including medicine, biology and ecology. Features applications from a range of disciplines, with implementation in R, SAS and/or ADMB. Provides all program code and software extensions on a supporting website. Confines supporting theory to the final chapters to maintain a readable and pragmatic focus of the preceding chapters. This book is not just an accessible and practical text about maximum likelihood, it is a comprehensive guide to modern maximum likelihood estimation and inference. It will be of interest to readers of all levels, from novice to expert. It will be of great benefit to researchers, and to students of statistics from senior undergraduate to graduate level. For use as a course text, exercises are provided at the end of each chapter.

Clinical Trials with Missing Data

Author : Michael O'Kelly
Publisher : John Wiley & Sons
ISBN 13 : 1118460707
Total Pages : 472 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Clinical Trials with Missing Data by : Michael O'Kelly

Download or read book Clinical Trials with Missing Data written by Michael O'Kelly and published by John Wiley & Sons. This book was released on 2014-04-07 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included – the reader is given a toolbox for implementing analyses under a variety of assumptions.