Artificial Nucleases

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540201120
Total Pages : 330 pages
Book Rating : 4.2/5 (11 download)

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Book Synopsis Artificial Nucleases by : Marina A. Zenkova

Download or read book Artificial Nucleases written by Marina A. Zenkova and published by Springer Science & Business Media. This book was released on 2004-01-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.

The Biological Chemistry of the Elements

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Publisher : Oxford University Press
ISBN 13 : 9780198508489
Total Pages : 608 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis The Biological Chemistry of the Elements by : J. J. R. Frausto da Silva

Download or read book The Biological Chemistry of the Elements written by J. J. R. Frausto da Silva and published by Oxford University Press. This book was released on 2001-08-16 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the functional role of the twenty inorganic elements essential to life in living organisms.

Heterocyclic Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 3662077574
Total Pages : 649 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Heterocyclic Chemistry by : Radha R. Gupta

Download or read book Heterocyclic Chemistry written by Radha R. Gupta and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced text-cum-reference book presents a comprehensive account of the syntheses, reactions, properties and applications of all the most significant classes of heterocyclic compounds. This second volume in the series is an essential tool not only for advanced undergraduates and graduates, but also for academic and industrial researchers in organic, medicinal, pharmaceutical, dye and agricultural chemistry.

Molecular Magnetism

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Publisher : Courier Dover Publications
ISBN 13 : 0486837424
Total Pages : 419 pages
Book Rating : 4.4/5 (868 download)

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Book Synopsis Molecular Magnetism by : Olivier Kahn

Download or read book Molecular Magnetism written by Olivier Kahn and published by Courier Dover Publications. This book was released on 2021-11-17 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly regarded and historic book covers basic concepts of magnetization and magnetic susceptibility, establishes the fundamental equations of molecular magnetism, and examines molecules containing a unique magnetic center. 2019 edition.

Bistatic SAR System and Signal Processing Technology

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Publisher : Springer
ISBN 13 : 9811030782
Total Pages : 286 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Bistatic SAR System and Signal Processing Technology by : Robert Wang

Download or read book Bistatic SAR System and Signal Processing Technology written by Robert Wang and published by Springer. This book was released on 2017-12-26 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports the latest results in the study of Bistatic/Multistatic SAR system and signal processing techniques. Novel research ideas and experimental verification have been collected on all kinds of configurations of Bistatic/Multistatic SAR system, including the preliminary construction of system model, imaging algorithm design, mission design and the corresponding application representations etc. Handy well-prepared tables are provided for readers’ quick-reference, and the practical design of an interferometric SAR system is illustrated step by step. The book will be of interest to university researchers, R&D engineers and graduate students in Remote Sensing who wish to learn the core principles, methods, algorithms, and applications of Bistatic/Multistatic SAR system.

Mutation Breeding

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Publisher : Cambridge University Press
ISBN 13 : 9780521470742
Total Pages : 372 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Mutation Breeding by : A. M. van Harten

Download or read book Mutation Breeding written by A. M. van Harten and published by Cambridge University Press. This book was released on 1998-06-25 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential and comprehensive summary for all plant breeders.

Metastable Microstructures

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Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Metastable Microstructures by : Dipankar Banerjee

Download or read book Metastable Microstructures written by Dipankar Banerjee and published by . This book was released on 1993 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Food Hygiene and Toxicology in Ready-to-Eat Foods

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Publisher : Academic Press
ISBN 13 : 0128020083
Total Pages : 480 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Food Hygiene and Toxicology in Ready-to-Eat Foods by : Parthena Kotzekidou

Download or read book Food Hygiene and Toxicology in Ready-to-Eat Foods written by Parthena Kotzekidou and published by Academic Press. This book was released on 2016-04-27 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Hygiene and Toxicology in Ready-to-Eat Foods is a solid reference for anyone in the food industry needing to understand the complex issues and mechanisms of biological control and chemical hazards to ensure food safety. infectious and non-infectious contaminants in raw, minimally processed, and prepared foods are covered in detail, as well as effective measures to avoid foodborne infections and intoxications. The book is written by an international team of experts presenting the most up-to-date research in the field, and provides current applications and guidance to enhance food safety in the food industry. Strategies and recommendations for each food category include, among others, how to avoid cross-contamination of pathogens, the proper uses of antimicrobial coatings and spray cleanings of fresh produce, and acrylamide reduction during processing. leafy vegetables, fruit juices, nuts, meat and dairy products are some of the ready-to-eat foods covered. - Provides the latest on research and development in the field of food safety incorporating practical real life examples for microbiological risk assessment and reduction in the food industry - Includes specific aspects of potential contamination and the importance of various risks associated with ready-to-eat foods - Describes potential harmful agents that may arise in foods during processing and packaging - Presents information on psychrotropic pathogens and food poisoning strains, effect of temperature, Salmonella, Listeria, Escherichia coli, Bacillus cereus, Norovirus, parasites, fungal microbiota, enterotoxins, and more

Cyclin Dependent Kinase 5 (Cdk5)

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Publisher : Springer Science & Business Media
ISBN 13 : 0387788875
Total Pages : 326 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Cyclin Dependent Kinase 5 (Cdk5) by : Nancy Y. Ip

Download or read book Cyclin Dependent Kinase 5 (Cdk5) written by Nancy Y. Ip and published by Springer Science & Business Media. This book was released on 2009-02-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.

Tree Flora of Malaya

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Publisher :
ISBN 13 : 9780582724136
Total Pages : 444 pages
Book Rating : 4.7/5 (241 download)

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Book Synopsis Tree Flora of Malaya by : Malaysia. Forest Department

Download or read book Tree Flora of Malaya written by Malaysia. Forest Department and published by . This book was released on 1972 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metallic Alloys: Experimental and Theoretical Perspectives

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792327011
Total Pages : 486 pages
Book Rating : 4.3/5 (27 download)

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Book Synopsis Metallic Alloys: Experimental and Theoretical Perspectives by : J.S. Faulkner

Download or read book Metallic Alloys: Experimental and Theoretical Perspectives written by J.S. Faulkner and published by Springer Science & Business Media. This book was released on 1994-02-28 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of new materials is recognized as one of the major elements in the overall technological evolution that must go on in order to sustain and even improve the quality of life for citizens of all nations. There are many components to this development, but one is to achieve a better understanding of the properties of materials using the most sophisticated scientific tools that are available. As condensed matter physicists and materials scientists work toward this goal, they find that it is useful to divide their efforts and focus on specific areas, because certain analytical and theoretical techniques will be more useful for the study of one class of materials than another. One such area is the study of metals and metallic alloys, which are used in the manufacture of products as diverse as automobiles and space stations. Progress in this area has been very rapid in recent years, and the new developments come from many different countries. For these reasons the Advanced Research Workshop Programme in the NATO Scientific Affairs Division has seen fit to sponsor several meetings to bring together the researchers and students working in this field from the NATO countries and elsewhere. There have been a series of NATO-ASI's that have dealt with the results of research on the electronic structure of materials and the properties of metals, alloys, and interfaces. They are: "Electrons in finite and infinite structures" P. Phariseau and L.