Single Particle Studies Using Optical Trapping And Manipulation

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Single Particle Studies Using Optical Trapping and Manipulation

Author : Zhiyong Gong
Publisher :
ISBN 13 :
Total Pages : 186 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Single Particle Studies Using Optical Trapping and Manipulation by : Zhiyong Gong

Download or read book Single Particle Studies Using Optical Trapping and Manipulation written by Zhiyong Gong and published by . This book was released on 2019 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particles of nanometer- and micrometer-size, including diverse types of aerosols, dusts, and material powders, pose significant influence on environment, climate, human health, and material properties. Our understanding towards these particles and materials is mainly established from bulk samples and from particles deposited on substrates or dispersed in liquid solutions. However, fundamental properties and interactions of single particles cannot be fully resolved by characterizing bulk materials or deposited particles. Pristine physicochemical properties and rudimentary gas-particle interactions can only be investigated from single particles in their native states. The goal of this dissertation is to study single particles in gaseous environment with minimum external interferences. Diverse optical trapping (OT) methods for trapping and manipulating single airborne particles were explored and summarized. These configurations are categorized into radiation-pressure traps, photophoretic traps, and universal optical traps (UOT), according to particle’s absorbance. The UOT configurations are able to trap and manipulate a wide variety of single particles, including transparent and absorbing, spherical and irregular, inorganic and biological particles. Four key aspects of these OTs, simplicity, robustness, flexibility, and efficiency, are brought up to evaluate OT capabilities, providing a guidance to select the optimal optical configuration for specific applications. With single particles stably trapped, optical manipulations and characterizations can therefore be interrogated. Single-particle manipulations in air from one-dimension to three-dimension are reviewed; pulling and pushing single optically trapped particles along a Gaussian laser beam were explored and explained. Cavity ringdown spectroscopy is integrated with OTs to measure the light extinctions of trapped particles. Microscopic imaging and Raman systems are combined with OTs to examine the trapped particles. A number of application examples of this optical trapping-Raman spectroscopy system are demonstrated, including online characterizing carbon particles, effectively bleaching fluorescence in dye-doped polymer microspheres, acquiring clean Raman spectra of single biological particles, and monitoring chemical reactions in single biological particles. Optical trapping, associated with advanced laser spectroscopic techniques, offer a great flexibility for trapping, manipulating, characterizing, and monitoring single particles in air.

Optical Trapping and Manipulation of Neutral Particles Using Lasers

Author : Arthur Ashkin
Publisher : World Scientific Publishing Company Incorporated
ISBN 13 : 9789810240578
Total Pages : 915 pages
Book Rating : 4.2/5 (45 download)

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Book Synopsis Optical Trapping and Manipulation of Neutral Particles Using Lasers by : Arthur Ashkin

Download or read book Optical Trapping and Manipulation of Neutral Particles Using Lasers written by Arthur Ashkin and published by World Scientific Publishing Company Incorporated. This book was released on 2006 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume contains selected papers and extensive commentaries on laser trapping and manipulation of neutral particles using radiation pressure forces. Such techniques apply to a variety of small particles, such as atoms, molecules, macroscopic dielectric particles, living cells, and organelles within cells. These optical methods have had a revolutionary impact on the fields of atomic and molecular physics, biophysics, and many aspects of nanotechnology.In atomic physics, the trapping and cooling of atoms down to nanokelvins and even picokelvin temperatures are possible. These are the lowest temperatures in the universe. This made possible the first demonstration of Bose-Einstein condensation of atomic and molecular vapors. Some of the applications are high precision atomic clocks, gyroscopes, the measurement of gravity, cryptology, atomic computers, cavity quantum electrodynamics and coherent atom lasers.A major application in biophysics is the study of the mechanical properties of the many types of motor molecules, mechanoenzymes, and other macromolecules responsible for the motion of organelles within cells and the locomotion of entire cells. Unique in vitro and in vivo assays study the driving forces, stepping motion, kinetics, and efficiency of these motors as they move along the cell's cytoskeleton. Positional and temporal resolutions have been achieved, making possible the study of RNA and DNA polymerases, as they undergo their various copying, backtracking, and error correcting functions on a single base pair basis.Many applications in nanotechnology involve particle and cell sorting, particle rotation, microfabrication of simple machines, microfluidics, and other micrometer devices. The number of applications continues to grow at a rapid rate.The author is the discoverer of optical trapping and optical tweezers. With his colleagues, he first demonstrated optical levitation, the trapping of atoms, and tweezer trapping and manipulation of living cells and biological particles.This is the only review volume covering the many fields of optical trapping and manipulation. The intention is to provide a selective guide to the literature and to teach how optical traps really work.

Fiber-Based Optical Trapping and Manipulation

Author : Baojun Li
Publisher : Nova Science Publishers
ISBN 13 : 9781634859981
Total Pages : 0 pages
Book Rating : 4.8/5 (599 download)

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Book Synopsis Fiber-Based Optical Trapping and Manipulation by : Baojun Li

Download or read book Fiber-Based Optical Trapping and Manipulation written by Baojun Li and published by Nova Science Publishers. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its first report in 1970 by A. Ashkin, optical trapping and manipulation has been widely used in the interdisciplines of micro- and nano-photonics, biophotonics, biomedicine, etc. A conventional tool for optical trapping and manipulation is the conventional optical tweezer (COT), the core part of which is a free-space focused laser beam. However, manipulation with COTs has some limitations such as manipulation inflexibility, bulky structure, diffraction limitation for nanoparticles, and limited integration functions. The introduction of optical fiber-based optical trapping and manipulation has solved these limitations. Using optical fibers with different configurations, optical trapping and manipulation with multiple functions can be realised with high flexibility, precision, and integration. By launching laser beams with different wavelengths into the fiber, both the photothermal effect and optical force can be used for optical trapping and manipulation. For the optical force manipulation, both evanescent fields at the surface of a subwavelength optical fiber and light output from a fiber end can be used for optical manipulation. The manipulation with light output from a fiber end can be divided into dual fiber tweezers and single fiber tweezers. For single fiber tweezers, one can realise the stable trapping of single particles both in a contact and non-contact manner for further applications. In addition, single fiber tweezers can also be used for multiple particle trapping and cell assembly, which can further be used for the assembly of biophotonic components and devices. Furthermore, by placing microparticles, which act as microlens at the end facet of an optical fiber, the microlens can be served as a photonic nanojet. This fiber supported photonic nanojet can be easily used for the trapping and detection of nanoparticles and biomolecules. Optical fiber-based optical trapping and manipulation have the advantages of easy fabrication, compact configuration, flexible manipulation, easy integration, wide applicability, etc., which provides for a wide application of prospects in micro- and nano-photonics, biophotonics, and biomedicine.

Optical Trapping and Manipulation

Author : Philip Jones
Publisher : MDPI
ISBN 13 : 303943537X
Total Pages : 128 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Optical Trapping and Manipulation by : Philip Jones

Download or read book Optical Trapping and Manipulation written by Philip Jones and published by MDPI. This book was released on 2020-11-25 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are pleased to present “Optical Trapping and Manipulation: From Fundamentals to Applications”, a Special Issue of Micromachines dedicated to the latest research in optical trapping. In recognition of the broad impact of optical manipulation techniques across disciplines, this Special Issue collected contributions related to all aspects of optical trapping and manipulation. Both theoretical and experimental studies were welcome, and applications of optical manipulation methods in fields including (but not limited to) single molecule biophysics, cell biology, nanotechnology, atmospheric chemistry, and fundamental optics were particularly welcome in order to showcase the breadth of the current research. The Special Issue accepted diverse forms of contributions, including research papers, short communications, methods, and review articles representing the state-of-the-art in optical trapping.

Optical Tweezers

Author : Philip H. Jones
Publisher : Cambridge University Press
ISBN 13 : 1107051169
Total Pages : 565 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Optical Tweezers by : Philip H. Jones

Download or read book Optical Tweezers written by Philip H. Jones and published by Cambridge University Press. This book was released on 2015-12-03 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the theory, practice and applications of optical tweezers, combining state-of-the-art research with a strong pedagogic approach.

Optical Trapping And Manipulation Of Neutral Particles Using Lasers: A Reprint Volume With Commentaries

Author : Arthur Ashkin
Publisher : World Scientific
ISBN 13 : 9814494348
Total Pages : 941 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Optical Trapping And Manipulation Of Neutral Particles Using Lasers: A Reprint Volume With Commentaries by : Arthur Ashkin

Download or read book Optical Trapping And Manipulation Of Neutral Particles Using Lasers: A Reprint Volume With Commentaries written by Arthur Ashkin and published by World Scientific. This book was released on 2006-12-29 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume contains selected papers and extensive commentaries on laser trapping and manipulation of neutral particles using radiation pressure forces. Such techniques apply to a variety of small particles, such as atoms, molecules, macroscopic dielectric particles, living cells, and organelles within cells. These optical methods have had a revolutionary impact on the fields of atomic and molecular physics, biophysics, and many aspects of nanotechnology.In atomic physics, the trapping and cooling of atoms down to nanokelvins and even picokelvin temperatures are possible. These are the lowest temperatures in the universe. This made possible the first demonstration of Bose-Einstein condensation of atomic and molecular vapors. Some of the applications are high precision atomic clocks, gyroscopes, the measurement of gravity, cryptology, atomic computers, cavity quantum electrodynamics and coherent atom lasers.A major application in biophysics is the study of the mechanical properties of the many types of motor molecules, mechanoenzymes, and other macromolecules responsible for the motion of organelles within cells and the locomotion of entire cells. Unique in vitro and in vivo assays study the driving forces, stepping motion, kinetics, and efficiency of these motors as they move along the cell's cytoskeleton. Positional and temporal resolutions have been achieved, making possible the study of RNA and DNA polymerases, as they undergo their various copying, backtracking, and error correcting functions on a single base pair basis.Many applications in nanotechnology involve particle and cell sorting, particle rotation, microfabrication of simple machines, microfluidics, and other micrometer devices. The number of applications continues to grow at a rapid rate.The author is the discoverer of optical trapping and optical tweezers. With his colleagues, he first demonstrated optical levitation, the trapping of atoms, and tweezer trapping and manipulation of living cells and biological particles.This is the only review volume covering the many fields of optical trapping and manipulation. The intention is to provide a selective guide to the literature and to teach how optical traps really work.

Manipulation of Micro Scale Particles in an Optical Trap Using Interferometry

Author : National Aeronautics and Space Adm Nasa
Publisher : Independently Published
ISBN 13 : 9781724096661
Total Pages : 26 pages
Book Rating : 4.0/5 (966 download)

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Book Synopsis Manipulation of Micro Scale Particles in an Optical Trap Using Interferometry by : National Aeronautics and Space Adm Nasa

Download or read book Manipulation of Micro Scale Particles in an Optical Trap Using Interferometry written by National Aeronautics and Space Adm Nasa and published by Independently Published. This book was released on 2018-09-27 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research shows that micro particles can be manipulated via interferometric patterns superimposed on an optical tweezers beam. Interferometry allows the manipulation of intensity distributions, and thus, force distributions on a trapped particle. To demonstrate the feasibility of such manipulation, 458 nm light, from an argon-ion laser, was injected into a Mach Zender interferometer. One mirror in the interferometer was oscillated with a piezoelectric phase modulator. The light from the interferometer was then injected into a microscope to trap a 9.75 micron polystyrene sphere. By varying the phase modulation, the sphere was made to oscillate in a controlled fashion. Seibel, Robin Glenn Research Center NASA/CR-2002-211975, NAS 1.26:211975, E-13644

Characterization of Single Nanoparticles

Author : Steven Jones
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (954 download)

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Book Synopsis Characterization of Single Nanoparticles by : Steven Jones

Download or read book Characterization of Single Nanoparticles written by Steven Jones and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical trapping is a method which uses focused laser light to manipulate small objects. This optical manipulation can be scaled below the diffraction limit by using interactions between light and apertures in a metal film to localize electric fields. This method can trap objects as small as several nanometers. The ability to determine the properties of a trapped nanoparticle is among the most pressing issues to the utilization of this method to a broader range of research and industrial applications. Presented here are two methods which demonstrate the ability to determine the properties of a trapped nanoparticle.The first method incorporates Raman spectroscopy into a trapping setup to obtain single particle identification. Raman spectroscopy provides a way to uniquely identify an object based on the light it scatters. Because Raman scattering is an intrinsically weak process, it has been difficult to obtain single particle sensitivity. Using localized electric fields at the trapping aperture, the Raman integrated trapping setup greatly enhances the optical interaction with the trapped particle enabling the required sensitivity. In this work, the trapping and identification of 20 nm titania and polystyrene nanoparticles is demonstrated.The second method uses an aperture assisted optical trap to detect the response of a magnetite nanoparticle to a varying applied magnetic field. This information is then used to determine the magnetic susceptibility, remanence, refractive index, and size distribution of the trapped particle.

Thermoplasmonics

Author : Guillaume Baffou
Publisher : Cambridge University Press
ISBN 13 : 1108307868
Total Pages : 310 pages
Book Rating : 4.1/5 (83 download)

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Book Synopsis Thermoplasmonics by : Guillaume Baffou

Download or read book Thermoplasmonics written by Guillaume Baffou and published by Cambridge University Press. This book was released on 2017-10-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasmonics is an important branch of optics concerned with the interaction of metals with light. Under appropriate illumination, metal nanoparticles can exhibit enhanced light absorption, becoming nanosources of heat that can be precisely controlled. This book provides an overview of the exciting new field of thermoplasmonics and a detailed discussion of its theoretical underpinning in nanophotonics. This topic has developed rapidly in the last decade, and is now a highly-active area of research due to countless applications in nanoengineering and nanomedicine. These important applications include photothermal cancer therapy, drug and gene delivery, nanochemistry and photothermal imaging. This timely and self-contained text is suited to all researchers and graduate students working in plasmonics, nano-optics and thermal-induced processes at the nanoscale.

Optical Tweezers

Author : Miles J. Padgett
Publisher : CRC Press
ISBN 13 : 1420074148
Total Pages : 510 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Optical Tweezers by : Miles J. Padgett

Download or read book Optical Tweezers written by Miles J. Padgett and published by CRC Press. This book was released on 2010-06-02 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The technical development of optical tweezers, along with their application in the biological and physical sciences, has progressed significantly since the demonstration of an optical trap for micron-sized particles based on a single, tightly focused laser beam was first reported more than twenty years ago. Bringing together many landmark papers on

Structured Light Fields

Author : Mike Wördemann
Publisher : Springer Science & Business Media
ISBN 13 : 3642293239
Total Pages : 139 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Structured Light Fields by : Mike Wördemann

Download or read book Structured Light Fields written by Mike Wördemann and published by Springer Science & Business Media. This book was released on 2012-05-16 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The optical trapping of colloidal matter is an unequalled field of technology for enabling precise handling of particles on microscopic scales, solely by the force of light. Although the basic concept of optical tweezers, which are based on a single laser beam, has matured and found a vast number of exciting applications, in particular in the life sciences, there are strong demands for more sophisticated approaches. This thesis gives an introductory overview of existing optical micromanipulation techniques and reviews the state-of-the-art of the emerging field of structured light fields and their applications in optical trapping, micromanipulation, and organisation. The author presents established, and introduces novel concepts for the holographic and non-holographic shaping of a light field. A special emphasis of the work is the demonstration of advanced applications of the thus created structured light fields in optical micromanipulation, utilising various geometries and unconventional light propagation properties. While most of the concepts developed are demonstrated with artificial microscopic reference particles, the work concludes with a comprehensive demonstration of optical control and alignment of bacterial cells, and hierarchical supramolecular organisation utilising dedicated nanocontainer particles.

Optical Pulling, Optical Deflection, and Optical Trapping of Single Airborne Particles Using Negative Photophoresis

Author : Adam Hart
Publisher :
ISBN 13 :
Total Pages : 65 pages
Book Rating : 4.:/5 (951 download)

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Book Synopsis Optical Pulling, Optical Deflection, and Optical Trapping of Single Airborne Particles Using Negative Photophoresis by : Adam Hart

Download or read book Optical Pulling, Optical Deflection, and Optical Trapping of Single Airborne Particles Using Negative Photophoresis written by Adam Hart and published by . This book was released on 2016 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical manipulation is the use of light to control the motion of objects. This thesis focuses on the development of optical transportation technology via optical pulling with application to the characterization of single airborne particles. Optical pulling, optical deflection, and optical trapping of single airborne particles using negative photophoresis force were demonstrated for the first time. Optical pulling and deflection were demonstrated for multiple absorbing particles. Raman scattering spectra of optically pulled particles were collected, thus demonstrating a method for particle identification. Using photography, digital video images were collected and analyzed for optically pulled and deflected particles. Optically pulled particles moved at a constant velocity for a given laser beam power. The velocity of optically pulled particles increased nonlinearly as laser power increased, approaching a saturation limitation. This saturation limitation was found to change with the atmospheric pressure. The efficiency for optical deflection was found to increase as the beam power ratio, deflection to pulling, increased approaching the limit of 100\%. Using a fast photodiode, scattering light signals were collected from optically pulled and deflected particles, which were found to be periodic, suggesting a constant rotational frequency in the motion. This rotational frequency was found to depend on laser beam power. From the video images and scattering light data, theoretical models for optical pulling and optical deflection were derived. Optical manipulation and characterization of single airborne particles is of significance for the analysis related to air pollution, human health, and global climate change.

Microrheology with Optical Tweezers

Author : Manlio Tassieri
Publisher : CRC Press
ISBN 13 : 1315341220
Total Pages : 356 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Microrheology with Optical Tweezers by : Manlio Tassieri

Download or read book Microrheology with Optical Tweezers written by Manlio Tassieri and published by CRC Press. This book was released on 2016-10-14 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to the pioneering works of Ashkin and coworkers, optical tweezers (OTs) have become an invaluable tool for myriad studies throughout the natural sciences. Their success relies on the fact that they can be considered as exceptionally sensitive transducers that are able to resolve pN forces and nm displacements, with high temporal resolution, down to μs. Hence their application to study a wide range of biological phenomena such as measuring the compliance of bacterial tails, the forces exerted by a single motor protein, and the mechanical properties of human red blood cells and of individual biological molecules. The number of articles related to them totals to a whopping 58,000 (source Google Scholar)! Microrheology is a branch of rheology, but it works at micrometer length scales and with microliter sample volumes. Therefore, microrheology techniques have been revealed to be very useful tools for all those rheological/mechanical studies where rare or precious materials are employed, such as in biological and biomedical studies. The aim of this book is to provide a pedagogical introduction to the physics principles governing both the optical tweezers and their application in the field of microrheology of complex materials. This is achieved by following a linear path that starts from a narrative introduction of the "nature of light," followed by a rigorous description of the fundamental equations governing the propagation of light through matter. Moreover, some of the many possible instrumental configurations are presented, especially those that better adapt to perform microrheology measurements. In order to better appreciate the microrheological methods with optical tweezers explored in this book, informative introductions to the basic concepts of linear rheology, statistical mechanics, and the most popular microrheology techniques are also given. Furthermore, an enlightening prologue to the general applications of optical tweezers different from rheological purposes is provided at the end of the book.

Handbook of Single-Molecule Biophysics

Author : Peter Hinterdorfer
Publisher : Springer Science & Business Media
ISBN 13 : 0387764976
Total Pages : 634 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Handbook of Single-Molecule Biophysics by : Peter Hinterdorfer

Download or read book Handbook of Single-Molecule Biophysics written by Peter Hinterdorfer and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

The Mie Theory

Author : Wolfram Hergert
Publisher : Springer
ISBN 13 : 3642287387
Total Pages : 268 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis The Mie Theory by : Wolfram Hergert

Download or read book The Mie Theory written by Wolfram Hergert and published by Springer. This book was released on 2012-06-30 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents in a concise way the Mie theory and its current applications. It begins with an overview of current theories, computational methods, experimental techniques, and applications of optics of small particles. There is also some biographic information on Gustav Mie, who published his famous paper on the colour of Gold colloids in 1908. The Mie solution for the light scattering of small spherical particles set the basis for more advanced scattering theories and today there are many methods to calculate light scattering and absorption for practically any shape and composition of particles. The optics of small particles is of interest in industrial, atmospheric, astronomic and other research. The book covers the latest developments in divers fields in scattering theory such as plasmon resonance, multiple scattering and optical force.

Manipulating Microscopic Objects. A Study on Optical Tweezers and Acoustic Levitation

Author : Marius Martin
Publisher : GRIN Verlag
ISBN 13 : 3346846970
Total Pages : 37 pages
Book Rating : 4.3/5 (468 download)

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Book Synopsis Manipulating Microscopic Objects. A Study on Optical Tweezers and Acoustic Levitation by : Marius Martin

Download or read book Manipulating Microscopic Objects. A Study on Optical Tweezers and Acoustic Levitation written by Marius Martin and published by GRIN Verlag. This book was released on 2023-03-30 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bachelor Thesis from the year 2023 in the subject Physics - Applied physics, University of Aberdeen, language: English, abstract: This thesis investigates two powerful techniques for manipulating and studying microscopic particles: optical tweezers and acoustic levitation. Optical tweezers use the force of light to trap and manipulate small particles, while acoustic levitation uses sound waves to levitate particles in mid-air. The first part of the thesis focuses on the construction and optimization of an optical tweezers system. The system is build using high-powered laser, optics for focusing the laser beam, and a position detection and control system. the second part of this thesis explores the use of acoustic levitation for the manipulation of micro spheres. The acoustic levitation system is designed and constructed using 72 transducers. The system is characterized using measurements of the acoustic field and the resulting levitation forces. The levitation of micro spheres is demonstrated. This thesis would provide a detailed investigation of two powerful techniques for the manipulation of microscopic particles.

Optical Nanomanipulation

Author : David L Andrews
Publisher : Morgan & Claypool Publishers
ISBN 13 : 168174466X
Total Pages : 135 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis Optical Nanomanipulation by : David L Andrews

Download or read book Optical Nanomanipulation written by David L Andrews and published by Morgan & Claypool Publishers. This book was released on 2017-01-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad introductory survey of this remarkable field, aiming to establish and clearly differentiate its physical principles, and also to provide a snapshot portrait of many of the most prominent current applications. Primary emphasis is placed on developing an understanding of the fundamental photonic origin behind the mechanism that operates in each type of effect. To this end, the first few chapters introduce and develop core theory, focusing on the physical significance and source of the most salient parameters, and revealing the detailed interplay between the key material and optical properties. Where appropriate, both classical and photonic (quantum mechanical) representations are discussed. The number of equations is purposely kept to a minimum, and only a broad background in optical physics is assumed. With copious examples and illustrations, each of the subsequent chapters then sets out to explain and exhibit the main features and uses of the various distinct types of mechanism that can be involved in optical nanomanipulation, including some of the very latest developments. To complete the scene, we also briefly discuss applications to larger, biological particles. Overall, this book aims to deliver to the non-specialist an amenable introduction to the technically more advanced literature on individual manipulation methods. Full references to the original research papers are given throughout, and an up-to-date bibliography is provided for each chapter, which directs the reader to other selected, more specialised sources.