Single Molecule Tools For Bioanalysis

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Single-Molecule Tools for Bioanalysis

Author : Shuo Huang
Publisher : CRC Press
ISBN 13 : 1000409171
Total Pages : 278 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Single-Molecule Tools for Bioanalysis by : Shuo Huang

Download or read book Single-Molecule Tools for Bioanalysis written by Shuo Huang and published by CRC Press. This book was released on 2022-05-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last three decades, the fast development of single-molecule techniques has revolutionized the way we observe and understand biological processes. Some of these techniques have been further adapted as tools for bioanalysis. This book summarizes and details the frontiers of the development of these tools as well as their applications. The contributors are young and established researchers in their respective fields. The main content originates from the lecture notes of a chemistry graduate course taught by the book editor at Nanjing University. This book is suitable to be used as a textbook for a high-level undergraduate or an entry-level graduate course. The systematically written content provides a thorough illustration of the mechanisms of each methodology presented.

Single Molecule Analysis

Author : Iddo Heller
Publisher : Humana
ISBN 13 : 9781071633762
Total Pages : 0 pages
Book Rating : 4.6/5 (337 download)

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Book Synopsis Single Molecule Analysis by : Iddo Heller

Download or read book Single Molecule Analysis written by Iddo Heller and published by Humana. This book was released on 2023-11-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition volume expands on the previous editions with new discussions on the latest techniques and developments in the field. The chapters in this book are organized into four parts, and cover topics such as optical tweezers; single-molecule fluorescence tools; atomic force microscopy; magnetic tweezers; applications to virus protein shells, unfolding of proteins, nucleic acids, motor proteins, in vivo and in vitro; and protocols to establish specific surface interactions and perform force calibration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Single Molecule Analysis: Methods and Protocols, Third Edition is a valuable resource for all researchers who want to learn more about this exciting and still expanding field. Chapters 2, 7, 8, 9, 12, 18, and 19 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Single Molecule Tools, Part A: Fluorescence Based Approaches

Author :
Publisher : Academic Press
ISBN 13 : 9780080959276
Total Pages : 528 pages
Book Rating : 4.9/5 (592 download)

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Book Synopsis Single Molecule Tools, Part A: Fluorescence Based Approaches by :

Download or read book Single Molecule Tools, Part A: Fluorescence Based Approaches written by and published by Academic Press. This book was released on 2010-08-17 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule tools have begun to revolutionize the molecular sciences, from biophysics to chemistry to cell biology. They hold the promise to be able to directly observe previously unseen molecular heterogeneities, quantitatively dissect complex reaction kinetics, ultimately miniaturize enzyme assays, image components of spatially distributed samples, probe the mechanical properties of single molecules in their native environment, and "just look at the thing" as anticipated by the visionary Richard Feynman already half a century ago. Single Molecule Tools, Part A: Fluorescence Based Approaches captures a snapshot of this vibrant, rapidly expanding field, presenting articles from pioneers in the field intended to guide both the newcomer and the expert through the intricacies of getting single molecule tools. Includes time-tested core methods and new innovations applicable to any researcher employing single molecule tools Methods included are useful to both established researchers and newcomers to the field Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

New Frontiers in Ultrasensitive Bioanalysis

Author : Xiao-Hong Nancy Xu
Publisher : John Wiley & Sons
ISBN 13 : 0470119497
Total Pages : 338 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis New Frontiers in Ultrasensitive Bioanalysis by : Xiao-Hong Nancy Xu

Download or read book New Frontiers in Ultrasensitive Bioanalysis written by Xiao-Hong Nancy Xu and published by John Wiley & Sons. This book was released on 2007-06-04 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of current research and developments in ultrasensitive bioanalysis New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.

Tools and Trends in Bioanalytical Chemistry

Author : Lauro Tatsuo Kubota
Publisher : Springer Nature
ISBN 13 : 3030823814
Total Pages : 559 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Tools and Trends in Bioanalytical Chemistry by : Lauro Tatsuo Kubota

Download or read book Tools and Trends in Bioanalytical Chemistry written by Lauro Tatsuo Kubota and published by Springer Nature. This book was released on 2021-11-25 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.

Methods in Enzymology

Author : Nils G. Walter
Publisher :
ISBN 13 : 9780123814821
Total Pages : 663 pages
Book Rating : 4.8/5 (148 download)

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Book Synopsis Methods in Enzymology by : Nils G. Walter

Download or read book Methods in Enzymology written by Nils G. Walter and published by . This book was released on 2010 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods

Author :
Publisher : Academic Press
ISBN 13 : 9780123814838
Total Pages : 720 pages
Book Rating : 4.8/5 (148 download)

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Book Synopsis Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods by :

Download or read book Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods written by and published by Academic Press. This book was released on 2010-07-09 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule tools have begun to revolutionize the molecular sciences, from biophysics to chemistry to cell biology. They hold the promise to be able to directly observe previously unseen molecular heterogeneities, quantitatively dissect complex reaction kinetics, ultimately miniaturize enzyme assays, image components of spatially distributed samples, probe the mechanical properties of single molecules in their native environment, and "just look at the thing" as anticipated by the visionary Richard Feynman already half a century ago. Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods captures a snapshot of this vibrant, rapidly expanding field, presenting articles from pioneers in the field intended to guide both the newcomer and the expert through the intricacies of getting single molecule tools. Includes time-tested core methods and new innovations applicable to any researcher employing single molecule tools Methods included are useful to both established researchers and newcomers to the field Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

Magnetic Tweezers for the Study of Protein Structure and Function

Author :
Publisher : Elsevier
ISBN 13 : 0443222304
Total Pages : 374 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Magnetic Tweezers for the Study of Protein Structure and Function by :

Download or read book Magnetic Tweezers for the Study of Protein Structure and Function written by and published by Elsevier. This book was released on 2024-03-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Tweezers for the Study of Protein Structure and Function, Volume 694 in the Methods in Enzymology serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Single membrane protein tethering for magnetic tweezer experiments, Membrane protein folding studies using a robust magnetic tweezer method, Magnetic tweezers in cell mechanics, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology serials Updated release includes the latest information on Magnetic Tweezers for the Study of Protein Structure and Function

Recent Advances in Fluorescent Probes for Super-Resolution Microscopy

Author : Chayan Kanti Nandi
Publisher : Frontiers Media SA
ISBN 13 : 2889710718
Total Pages : 105 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Recent Advances in Fluorescent Probes for Super-Resolution Microscopy by : Chayan Kanti Nandi

Download or read book Recent Advances in Fluorescent Probes for Super-Resolution Microscopy written by Chayan Kanti Nandi and published by Frontiers Media SA. This book was released on 2021-07-21 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods

Author :
Publisher : Academic Press
ISBN 13 : 9780123814821
Total Pages : 720 pages
Book Rating : 4.8/5 (148 download)

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Book Synopsis Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods by :

Download or read book Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods written by and published by Academic Press. This book was released on 2010-08-16 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule tools have begun to revolutionize the molecular sciences, from biophysics to chemistry to cell biology. They hold the promise to be able to directly observe previously unseen molecular heterogeneities, quantitatively dissect complex reaction kinetics, ultimately miniaturize enzyme assays, image components of spatially distributed samples, probe the mechanical properties of single molecules in their native environment, and "just look at the thing" as anticipated by the visionary Richard Feynman already half a century ago. Single Molecule Tools, Part B: Super-Resolution, Particle Tracking, Multiparameter, and Force Based Methods captures a snapshot of this vibrant, rapidly expanding field, presenting articles from pioneers in the field intended to guide both the newcomer and the expert through the intricacies of getting single molecule tools. Includes time-tested core methods and new innovations applicable to any researcher employing single molecule tools Methods included are useful to both established researchers and newcomers to the field Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

Single Molecule Tools

Author : Nils G. Walter
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.:/5 (781 download)

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Book Synopsis Single Molecule Tools by : Nils G. Walter

Download or read book Single Molecule Tools written by Nils G. Walter and published by . This book was released on 2010 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Micro and Nano Technologies in Bioanalysis

Author : James W. Lee
Publisher : Methods in Molecular Biology
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Micro and Nano Technologies in Bioanalysis by : James W. Lee

Download or read book Micro and Nano Technologies in Bioanalysis written by James W. Lee and published by Methods in Molecular Biology. This book was released on 2009-07-21 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, large-scale advances in technology have led to greater understanding of the world at the biomolecular level. In this book, expert researchers from across the globe explore the technology which makes this analysis possible.

Paper-Based Medical Diagnostic Devices

Author : Jeong Hoon Lee
Publisher : Springer Nature
ISBN 13 : 981158723X
Total Pages : 184 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Paper-Based Medical Diagnostic Devices by : Jeong Hoon Lee

Download or read book Paper-Based Medical Diagnostic Devices written by Jeong Hoon Lee and published by Springer Nature. This book was released on 2020-12-09 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book disseminates information on paper-based diagnostics devices and describes novel paper materials, fabrication techniques, and Basic Paper-based microfluidics/electronics theory. The section on sample preparation, paper-based electronics/sensors for developing paper-based point-of-care (POC) systems also contains detailed descriptions. In the application sections this book covers sensing technique for DNA/RNA, bacteria/virus and integration of lateral flow assay. The book provides deep understanding and knowledge of paper-based diagnostic device development in terms of concept, materials, fabrication and applications.

Laser Doppler Vibrometry for Non-Contact Diagnostics

Author : Kristian Kroschel
Publisher : Springer Nature
ISBN 13 : 3030466914
Total Pages : 187 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Laser Doppler Vibrometry for Non-Contact Diagnostics by : Kristian Kroschel

Download or read book Laser Doppler Vibrometry for Non-Contact Diagnostics written by Kristian Kroschel and published by Springer Nature. This book was released on 2020-06-09 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent outcomes of the collaborative “Tricorder” project, which brings together partners from industry, research institutes and hospitals to deliver an easy contactless alternative for electrocardiograms (ECG). Featuring contributions investigating the possible applications of laser Doppler vibrometry (LDV) signals for the remote measurement of vital parameters of the heart, the book provides insights into the vision and the history of the "Tricorder" project and the basic differences between the vibrocardiograms and electrocardiograms. It also discusses topics such as signal processing, heartbeat measurement techniques, respiration frequency and oxygen saturation determination, with a particular focus on the diagnostic value of the method presented, e.g., diagnosis of atrial fibrillation and estimation of the oxygen saturation in premature infants. Further, the authors review the advantages and drawbacks of the new method and the specific fields of application. This book will appeal to researchers and industry leaders interested in laser remote sensing for medical applications as well as medical professionals curious about new healthcare technologies.

Biomedical and Resonance Optics

Author : Leonid V. Tanin
Publisher : Springer Nature
ISBN 13 : 3030607739
Total Pages : 518 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Biomedical and Resonance Optics by : Leonid V. Tanin

Download or read book Biomedical and Resonance Optics written by Leonid V. Tanin and published by Springer Nature. This book was released on 2020-12-10 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses fundamentally new biomedical imaging methods, such as holography, holographic and resonant interferometry, and speckle optics. It focuses on the development of holographic interference microscopy and its use in the study of phase objects such as nerve and muscle fibers subjected to the influence of laser radiation, magnetic fields, and hyperbaric conditions. The book shows how the myelin sheath and even the axon itself exhibit waveguide properties, enabling a fresh new look at the mechanisms of information transmission in the human body. The book presents theoretically and experimentally tested holographic and speckle-optical methods and devices used for investigating complex, diffusely scattering surfaces such as skin and muscle tissue. Additionally, it gives broad discussion of the authors’ own original fundamental and applied research dedicated to helping physicians introduce new contact-less methods of diagnosis and treatment of diseases of the cardiovascular and neuromuscular systems into medical practice. The book is aimed at a broad spectrum of scientific specialists in the fields of speckle optics, holography, laser physics, morphology and cytochemistry, as well as medical professionals such as physiologists, neuropathologists, neurosurgeons, cardiologists and dentists.

Single-molecule Studies of Proteins

Author : Andres F. Oberhauser
Publisher : Springer Science & Business Media
ISBN 13 : 1461449219
Total Pages : 274 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Single-molecule Studies of Proteins by : Andres F. Oberhauser

Download or read book Single-molecule Studies of Proteins written by Andres F. Oberhauser and published by Springer Science & Business Media. This book was released on 2012-11-09 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.

Single Molecule Biology

Author : Alex Knight
Publisher : Academic Press
ISBN 13 : 9780123742278
Total Pages : 332 pages
Book Rating : 4.7/5 (422 download)

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Book Synopsis Single Molecule Biology by : Alex Knight

Download or read book Single Molecule Biology written by Alex Knight and published by Academic Press. This book was released on 2009 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert's perspective on future developments.