Sensitivity To Change

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Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Author : Agency for Health Care Research and Quality (U.S.)
Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Sensitivity to Change

Author : Emin Özsoy
Publisher : Springer Science & Business Media
ISBN 13 : 9401157588
Total Pages : 520 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Sensitivity to Change by : Emin Özsoy

Download or read book Sensitivity to Change written by Emin Özsoy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent decades have seen a degradation of the environmental quality in semi-enclosed seas, which are particularly sensitive to population pressures due to their naturally low flushing rates related to their geometry. The North Sea, Baltic Sea and the Black Sea are amongst the most seriously threatened seas in the Euro-Asian region. Each semi-enclosed sea has a distinct pattern of circulation, transport, mixing, associated with the particular geometry, topography, boundary processes, interior stratification, atmospheric forcing, ice fonnation, straits / sill controls, and the specific inputs of freshwater, nutrients and pollutants. The workshop investigated the distinctive physical and ecological characteristics of the three seas in a comparative manner, in order to identify the types of driving forces and dynamic controls operating on productivity, nutrient cycling, physical transport and mixing mechanisms. A comparative study of these controlling mechanisms would allow us to better understand ecosystem sensitivity in these different environments. The workshop presentations highlighted the complexity of the semi-enclosed seas related to the interaction amongst the physical, chemical and biological fields, and differences in time and space scales in each of the systems. Further, a strong climate signal exists in these systems, manifest in the interannual, interdecadal and longer term variability. Part of the variability appears connected with background climatic variability.

The Prevention and Treatment of Missing Data in Clinical Trials

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030918651X
Total Pages : 163 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Motor Control

Author : Anne Shumway-Cook
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975217667
Total Pages : 1270 pages
Book Rating : 4.9/5 (752 download)

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Book Synopsis Motor Control by : Anne Shumway-Cook

Download or read book Motor Control written by Anne Shumway-Cook and published by Lippincott Williams & Wilkins. This book was released on 2023-04-05 with total page 1270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor Control: Translating Research into Clinical Practice, 6th Edition, is the only text that bridges the gap between current and emerging motor control research and its application to clinical practice. Written by leading experts in the field, this classic resource prepares users to effectively assess, evaluate, and treat clients with problems related to postural control, mobility, and upper extremity function using today’s evidence-based best practices. This extensively revised 6th Edition reflects the latest advances in research and features updated images, clinical features, and case studies to ensure a confident transition to practice. Each chapter follows a consistent, straightforward format to simplify studying and reinforce understanding of normal control process issues, age-related issues, research on abnormal function, clinical applications of current research, and evidence to support treatments used in the rehabilitation of patients with motor control problems.

Emergent Techniques for Assessment of Visual Performance

Author : National Research Council
Publisher : National Academies Press
ISBN 13 :
Total Pages : 75 pages
Book Rating : 4./5 ( download)

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Book Synopsis Emergent Techniques for Assessment of Visual Performance by : National Research Council

Download or read book Emergent Techniques for Assessment of Visual Performance written by National Research Council and published by National Academies Press. This book was released on 1985-01-01 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent vision research has led to the emergence of new techniques that offer exciting potential for a more complete assessment of vision in clinical, industrial, and military settings. Emergent Techniques for Assessment of Visual Performance examines four areas of vision testing that offer potential for improved assessment of visual capability including: contrast sensitivity function, dark-focus of accommodation, dynamic visual acuity and dynamic depth tracking, and ambient and focal vision. In contrast to studies of accepted practices, this report focuses on emerging techniques that could help determine whether people have the vision necessary to do their jobs. In addition to examining some of these emerging techniques, the report identifies their usefulness in predicting performance on other visual and visual-motor tasks, and makes recommendations for future research. Emergent Techniques for Assessment of Visual Performance provides summary recommendations for research that will have significant value and policy implications for the next 5 to 10 years. The content and conclusions of this report can serve as a useful resource for those responsible for screening industrial and military visual function.

Sensitivity Analysis

Author : Emanuele Borgonovo
Publisher : Springer
ISBN 13 : 3319522590
Total Pages : 291 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Sensitivity Analysis by : Emanuele Borgonovo

Download or read book Sensitivity Analysis written by Emanuele Borgonovo and published by Springer. This book was released on 2017-04-19 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an expository introduction to the methodology of sensitivity analysis of model output. It is primarily intended for investigators, students and researchers that are familiar with mathematical models but are less familiar with the techniques for performing their sensitivity analysis. A variety of sensitivity methods have been developed over the years. This monograph helps the analyst in her/his first exploration of this world. The main goal is to foster the recognition of the crucial role of sensitivity analysis methods as the techniques that allow us to gain insights from quantitative models. Also, exercising rigor in performing sensitivity analysis becomes increasingly relevant both to decision makers and modelers. The book helps the analyst in structuring her/his sensitivity analysis quest properly, so as to obtain the correct answer to the corresponding managerial question. The first part of the book covers Deterministic Methods, including Tornado Diagrams; One-Way Sensitivity Analysis; Differentiation-Based Methods and Local Sensitivity Analysis with Constraints. The second part looks at Probabilistic Methods, including Regression-Based methods, Variance-Based Methods, and Distribution-Based methods. The final section looks at Applications, including capital budgeting, sensitivity analysis in climate change modelling and in the risk assessment of a lunar space mission.

Sensitivity Analysis: Matrix Methods in Demography and Ecology

Author : Hal Caswell
Publisher : Springer
ISBN 13 : 3030105342
Total Pages : 308 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Sensitivity Analysis: Matrix Methods in Demography and Ecology by : Hal Caswell

Download or read book Sensitivity Analysis: Matrix Methods in Demography and Ecology written by Hal Caswell and published by Springer. This book was released on 2019-04-02 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book shows how to use sensitivity analysis in demography. It presents new methods for individuals, cohorts, and populations, with applications to humans, other animals, and plants. The analyses are based on matrix formulations of age-classified, stage-classified, and multistate population models. Methods are presented for linear and nonlinear, deterministic and stochastic, and time-invariant and time-varying cases. Readers will discover results on the sensitivity of statistics of longevity, life disparity, occupancy times, the net reproductive rate, and statistics of Markov chain models in demography. They will also see applications of sensitivity analysis to population growth rates, stable population structures, reproductive value, equilibria under immigration and nonlinearity, and population cycles. Individual stochasticity is a theme throughout, with a focus that goes beyond expected values to include variances in demographic outcomes. The calculations are easily and accurately implemented in matrix-oriented programming languages such as Matlab or R. Sensitivity analysis will help readers create models to predict the effect of future changes, to evaluate policy effects, and to identify possible evolutionary responses to the environment. Complete with many examples of the application, the book will be of interest to researchers and graduate students in human demography and population biology. The material will also appeal to those in mathematical biology and applied mathematics.

Global Sensitivity Analysis

Author : Andrea Saltelli
Publisher : John Wiley & Sons
ISBN 13 : 9780470725177
Total Pages : 304 pages
Book Rating : 4.7/5 (251 download)

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Book Synopsis Global Sensitivity Analysis by : Andrea Saltelli

Download or read book Global Sensitivity Analysis written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.

Sensitivity Analysis in Practice

Author : Andrea Saltelli
Publisher : John Wiley & Sons
ISBN 13 : 047087094X
Total Pages : 232 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Sensitivity Analysis in Practice by : Andrea Saltelli

Download or read book Sensitivity Analysis in Practice written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitivity analysis should be considered a pre-requisite for statistical model building in any scientific discipline where modelling takes place. For a non-expert, choosing the method of analysis for their model is complex, and depends on a number of factors. This book guides the non-expert through their problem in order to enable them to choose and apply the most appropriate method. It offers a review of the state-of-the-art in sensitivity analysis, and is suitable for a wide range of practitioners. It is focussed on the use of SIMLAB – a widely distributed freely-available sensitivity analysis software package developed by the authors – for solving problems in sensitivity analysis of statistical models. Other key features: Provides an accessible overview of the current most widely used methods for sensitivity analysis. Opens with a detailed worked example to explain the motivation behind the book. Includes a range of examples to help illustrate the concepts discussed. Focuses on implementation of the methods in the software SIMLAB - a freely-available sensitivity analysis software package developed by the authors. Contains a large number of references to sources for further reading. Authored by the leading authorities on sensitivity analysis.

The Clinician's Guide to Anxiety Sensitivity Treatment and Assessment

Author : Jasper Smits
Publisher : Academic Press
ISBN 13 : 9780128134955
Total Pages : 0 pages
Book Rating : 4.1/5 (349 download)

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Book Synopsis The Clinician's Guide to Anxiety Sensitivity Treatment and Assessment by : Jasper Smits

Download or read book The Clinician's Guide to Anxiety Sensitivity Treatment and Assessment written by Jasper Smits and published by Academic Press. This book was released on 2018-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinician's Guide to Anxiety Sensitivity Treatment and Assessment provides evidence-based strategies for clinicians looking to treat, assess and better understand anxiety sensitivity in their patients. The book delivers detailed guidance on the theoretical background and empirical support for anxiety sensitivity treatment methods, assessment strategies, and how clinicians can best prepare for sessions with their clients. Bolstered by case studies throughout, it highlights anxiety sensitivity as a transdiagnostic risk factor while also looking at the importance of lower-order sensitivity factors (physical, social, cognitive) in treatment planning, implementation and evaluation.

Prevention of Treatment Failure

Author : Michael J. Lambert
Publisher : American Psychological Association (APA)
ISBN 13 : 9781433807824
Total Pages : 0 pages
Book Rating : 4.8/5 (78 download)

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Book Synopsis Prevention of Treatment Failure by : Michael J. Lambert

Download or read book Prevention of Treatment Failure written by Michael J. Lambert and published by American Psychological Association (APA). This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical evidence shows that treatment failure is a significant problem and one that practitioners routinely overlook. A substantial minority of patients either fail to gain a benefit from the treatments offered to them, or they outright worsen by the time they leave treatment. Intervening in a timely fashion with such individuals cannot occur if practitioners are unaware of which cases are likely to have this outcome. Prevention of Treatment Failure describes procedures and techniques that can be used by clinical practitioners and administrators to identify patients who are at risk for treatment failure. The book summarizes evidence that convincingly shows that a shift in routine care is needed, and that such a shift can be accomplished easily through integrating specific methods of monitoring patient treatment response on a frequent basis in routine care. Treatment response is placed in the context of historical views of healthy functioning and operationalized through the use of brief self-report scales. Providing alert-signals to therapists, along with problem-solving tools, is suggested as an evidence-based practice that substantially reduces patient deterioration and increases the chances of the return to normal functioning. The book also provides illustrations on how accumulated data resulting from monitoring patient treatment response can be used to improve systems of care.

Peabody Developmental Motor Scales

Author : M. Rhonda Folio
Publisher :
ISBN 13 : 9780761618218
Total Pages : 0 pages
Book Rating : 4.6/5 (182 download)

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Book Synopsis Peabody Developmental Motor Scales by : M. Rhonda Folio

Download or read book Peabody Developmental Motor Scales written by M. Rhonda Folio and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design Sensitivity

Author : Mark W. Lipsey
Publisher : SAGE
ISBN 13 : 9780803930636
Total Pages : 216 pages
Book Rating : 4.9/5 (36 download)

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Book Synopsis Design Sensitivity by : Mark W. Lipsey

Download or read book Design Sensitivity written by Mark W. Lipsey and published by SAGE. This book was released on 1990 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: All researchers face an important challenge - designing research that will have sufficient sensitivity to detect those effects it purports to investigate. Through careful explanations and selection of examples, this title examines the concept of design sensitivity and explains statistical power and the elements that determine it.

Sensitivity of Ecological Landscapes and Regions to Global Climatic Change

Author :
Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Sensitivity of Ecological Landscapes and Regions to Global Climatic Change by :

Download or read book Sensitivity of Ecological Landscapes and Regions to Global Climatic Change written by and published by . This book was released on 1989 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sensitivity Analysis in Linear Systems

Author : Assem Deif
Publisher : Springer Science & Business Media
ISBN 13 : 364282739X
Total Pages : 235 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Sensitivity Analysis in Linear Systems by : Assem Deif

Download or read book Sensitivity Analysis in Linear Systems written by Assem Deif and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: A text surveying perturbation techniques and sensitivity analysis of linear systems is an ambitious undertaking, considering the lack of basic comprehensive texts on the subject. A wide-ranging and global coverage of the topic is as yet missing, despite the existence of numerous monographs dealing with specific topics but generally of use to only a narrow category of people. In fact, most works approach this subject from the numerical analysis point of view. Indeed, researchers in this field have been most concerned with this topic, although engineers and scholars in all fields may find it equally interesting. One can state, without great exaggeration, that a great deal of engineering work is devoted to testing systems' sensitivity to changes in design parameters. As a rule, high-sensitivity elements are those which should be designed with utmost care. On the other hand, as the mathematical modelling serving for the design process is usually idealized and often inaccurately formulated, some unforeseen alterations may cause the system to behave in a slightly different manner. Sensitivity analysis can help the engineer innovate ways to minimize such system discrepancy, since it starts from the assumption of such a discrepancy between the ideal and the actual system.

Sensitivity of Mangrove Ecosystem to Changing Climate

Author : Abhijit Mitra
Publisher : Springer Science & Business Media
ISBN 13 : 8132215095
Total Pages : 338 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Sensitivity of Mangrove Ecosystem to Changing Climate by : Abhijit Mitra

Download or read book Sensitivity of Mangrove Ecosystem to Changing Climate written by Abhijit Mitra and published by Springer Science & Business Media. This book was released on 2013-08-13 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mangroves are basically salt tolerant forest ecosystems found mainly in tropical and sub-tropical inter-tidal regions. Till about 1960s, mangroves were largely viewed as “economically unproductive areas” and were therefore destroyed for reclaiming land for various economic and commercial activities. Gradually, with the passage of time, the economic and ecological benefits of mangroves have become visible and their importance is now well appreciated. Today, mangroves are observed in about 30 countries in tropical subtropical regions covering an area of about 99,300 Sq.Km. However, during the past 50 years, over 50% of the mangrove cover has been lost, mainly because of the increased pressure of human activities like shrimp farming and agriculture, forestry, salt extraction, urban development, tourist development and infrastructure. Also, dam on rivers, contamination of sea waters caused by heavy metals, oil spills, pesticides and other products etc. have been found to be responsible for the decline of mangroves. Although the temperature effect on growth and species diversity is not known, sea-level rise may pose a serious threat to these ecosystems The present book addresses all these important issues in separate chapters with some interesting case studies whose data may serve as pathfinder for future researches in the sphere of the influence of climate change on mangrove ecosystem. The role of mangroves in the sector of bioremediation is a unique feather in the crown of this coastal and brackishwater vegetation that may be taken up by the coastal industries in order to maintain the health of ambient environment. This book seeks to discover and to assess the vulnerability of climate change on mangrove flora and fauna, their role in carbon sequestration and some interesting case studies by some groups of dedicated researchers that may serve as the basis of future climate related policies.

Assessment Sensitivity

Author : John Gordon MacFarlane
Publisher :
ISBN 13 : 0199682755
Total Pages : 361 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Assessment Sensitivity by : John Gordon MacFarlane

Download or read book Assessment Sensitivity written by John Gordon MacFarlane and published by . This book was released on 2014 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: John MacFarlane debates how we might make sense of the idea that truth is relative, and how we might use this idea to give satisfying accounts of parts of our thought and talk that have resisted traditional methods of analysis. Although there is a substantial philosophical literature on relativism about truth, going back to Plato's Theaetetus, this literature (both pro and con) has tended to focus on refutations of the doctrine, or refutations of these refutations, at the expense of saying clearly what the doctrine is. In contrast, Assessment Sensitivity begins with a clear account of what it is to be a relativist about truth, and uses this view to give satisfying accounts of what we mean when we talk about what is tasty, what we know, what will happen, what might be the case, and what we ought to do. The book seeks to provide a richer framework for the description of linguistic practices than standard truth-conditional semantics affords: one that allows not just standard contextual sensitivity (sensitivity to features of the context in which an expression is used), but assessment sensitivity (sensitivity to features of the context from which a use of an expression is assessed). The Context and Content series is a forum for outstanding original research at the intersection of philosophy, linguistics, and cognitive science. The general editor is Francois Recanati (Institut Jean-Nicod, Paris).