Sensitivity Analysis

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Sensitivity Analysis

Author : Emanuele Borgonovo
Publisher : Springer
ISBN 13 : 3319522590
Total Pages : 291 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Sensitivity Analysis by : Emanuele Borgonovo

Download or read book Sensitivity Analysis written by Emanuele Borgonovo and published by Springer. This book was released on 2017-04-19 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an expository introduction to the methodology of sensitivity analysis of model output. It is primarily intended for investigators, students and researchers that are familiar with mathematical models but are less familiar with the techniques for performing their sensitivity analysis. A variety of sensitivity methods have been developed over the years. This monograph helps the analyst in her/his first exploration of this world. The main goal is to foster the recognition of the crucial role of sensitivity analysis methods as the techniques that allow us to gain insights from quantitative models. Also, exercising rigor in performing sensitivity analysis becomes increasingly relevant both to decision makers and modelers. The book helps the analyst in structuring her/his sensitivity analysis quest properly, so as to obtain the correct answer to the corresponding managerial question. The first part of the book covers Deterministic Methods, including Tornado Diagrams; One-Way Sensitivity Analysis; Differentiation-Based Methods and Local Sensitivity Analysis with Constraints. The second part looks at Probabilistic Methods, including Regression-Based methods, Variance-Based Methods, and Distribution-Based methods. The final section looks at Applications, including capital budgeting, sensitivity analysis in climate change modelling and in the risk assessment of a lunar space mission.

Sensitivity Analysis

Author : Andrea Saltelli
Publisher : Wiley
ISBN 13 : 9780470743829
Total Pages : 0 pages
Book Rating : 4.7/5 (438 download)

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Book Synopsis Sensitivity Analysis by : Andrea Saltelli

Download or read book Sensitivity Analysis written by Andrea Saltelli and published by Wiley. This book was released on 2009-03-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wiley Paperback Series makes valuable content more accessible to a new generation of statisticians, mathematicians and scientists. Sensitivity analysis is used to ascertain how a given model output depends upon the input parameters. This is an important method for checking the quality of a given model, as well as a powerful tool for checking the robustness and reliability of its analysis. The topic is acknowledged as essential for good modelling practice and is an implicit part of any modelling field. Offers an accessible introduction to sensitivity analysis. Covers all the latest research. Illustrates concepts with numerous examples, applications and case studies. Includes contributions from the leading researchers active in developing strategies for sensitivity analysis. The principles of sensitivity analysis are carefully described and suitable methods for approaching many types of problems are given. The book introduces the modeller to the entire casual assessment chain, from data to predictions, whilst explaining the impact of source uncertainties and framing assumptions. A ‘hitch-hikers guide’ is included to allow the more experienced reader to readily access specific applications. Modellers from a wide range of disciplines, including biostatistics, economics, environmental impact assessment, chemistry and engineering will benefit greatly from the numerous examples and applications. "Presents many different sensitivity analysis methodologies and demonstrates their usefulness in scientific research." (Zentralblatt MATH)

Sensitivity Analysis in Practice

Author : Andrea Saltelli
Publisher : John Wiley & Sons
ISBN 13 : 047087094X
Total Pages : 232 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Sensitivity Analysis in Practice by : Andrea Saltelli

Download or read book Sensitivity Analysis in Practice written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitivity analysis should be considered a pre-requisite for statistical model building in any scientific discipline where modelling takes place. For a non-expert, choosing the method of analysis for their model is complex, and depends on a number of factors. This book guides the non-expert through their problem in order to enable them to choose and apply the most appropriate method. It offers a review of the state-of-the-art in sensitivity analysis, and is suitable for a wide range of practitioners. It is focussed on the use of SIMLAB – a widely distributed freely-available sensitivity analysis software package developed by the authors – for solving problems in sensitivity analysis of statistical models. Other key features: Provides an accessible overview of the current most widely used methods for sensitivity analysis. Opens with a detailed worked example to explain the motivation behind the book. Includes a range of examples to help illustrate the concepts discussed. Focuses on implementation of the methods in the software SIMLAB - a freely-available sensitivity analysis software package developed by the authors. Contains a large number of references to sources for further reading. Authored by the leading authorities on sensitivity analysis.

The Prevention and Treatment of Missing Data in Clinical Trials

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030918651X
Total Pages : 163 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Global Sensitivity Analysis

Author : Andrea Saltelli
Publisher : John Wiley & Sons
ISBN 13 : 9780470725177
Total Pages : 304 pages
Book Rating : 4.7/5 (251 download)

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Book Synopsis Global Sensitivity Analysis by : Andrea Saltelli

Download or read book Global Sensitivity Analysis written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Author : Agency for Health Care Research and Quality (U.S.)
Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Sensitivity Analysis: Matrix Methods in Demography and Ecology

Author : Hal Caswell
Publisher : Springer
ISBN 13 : 3030105342
Total Pages : 308 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Sensitivity Analysis: Matrix Methods in Demography and Ecology by : Hal Caswell

Download or read book Sensitivity Analysis: Matrix Methods in Demography and Ecology written by Hal Caswell and published by Springer. This book was released on 2019-04-02 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book shows how to use sensitivity analysis in demography. It presents new methods for individuals, cohorts, and populations, with applications to humans, other animals, and plants. The analyses are based on matrix formulations of age-classified, stage-classified, and multistate population models. Methods are presented for linear and nonlinear, deterministic and stochastic, and time-invariant and time-varying cases. Readers will discover results on the sensitivity of statistics of longevity, life disparity, occupancy times, the net reproductive rate, and statistics of Markov chain models in demography. They will also see applications of sensitivity analysis to population growth rates, stable population structures, reproductive value, equilibria under immigration and nonlinearity, and population cycles. Individual stochasticity is a theme throughout, with a focus that goes beyond expected values to include variances in demographic outcomes. The calculations are easily and accurately implemented in matrix-oriented programming languages such as Matlab or R. Sensitivity analysis will help readers create models to predict the effect of future changes, to evaluate policy effects, and to identify possible evolutionary responses to the environment. Complete with many examples of the application, the book will be of interest to researchers and graduate students in human demography and population biology. The material will also appeal to those in mathematical biology and applied mathematics.

Sensitivity Analysis for Neural Networks

Author : Daniel S. Yeung
Publisher : Springer Science & Business Media
ISBN 13 : 3642025323
Total Pages : 89 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Sensitivity Analysis for Neural Networks by : Daniel S. Yeung

Download or read book Sensitivity Analysis for Neural Networks written by Daniel S. Yeung and published by Springer Science & Business Media. This book was released on 2009-11-09 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial neural networks are used to model systems that receive inputs and produce outputs. The relationships between the inputs and outputs and the representation parameters are critical issues in the design of related engineering systems, and sensitivity analysis concerns methods for analyzing these relationships. Perturbations of neural networks are caused by machine imprecision, and they can be simulated by embedding disturbances in the original inputs or connection weights, allowing us to study the characteristics of a function under small perturbations of its parameters. This is the first book to present a systematic description of sensitivity analysis methods for artificial neural networks. It covers sensitivity analysis of multilayer perceptron neural networks and radial basis function neural networks, two widely used models in the machine learning field. The authors examine the applications of such analysis in tasks such as feature selection, sample reduction, and network optimization. The book will be useful for engineers applying neural network sensitivity analysis to solve practical problems, and for researchers interested in foundational problems in neural networks.

Sensitivity Analysis in Earth Observation Modelling

Author : George P. Petropoulos
Publisher : Elsevier
ISBN 13 : 0128030313
Total Pages : 448 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Sensitivity Analysis in Earth Observation Modelling by : George P. Petropoulos

Download or read book Sensitivity Analysis in Earth Observation Modelling written by George P. Petropoulos and published by Elsevier. This book was released on 2016-10-07 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitivity Analysis in Earth Observation Modeling highlights the state-of-the-art in ongoing research investigations and new applications of sensitivity analysis in earth observation modeling. In this framework, original works concerned with the development or exploitation of diverse methods applied to different types of earth observation data or earth observation-based modeling approaches are included. An overview of sensitivity analysis methods and principles is provided first, followed by examples of applications and case studies of different sensitivity/uncertainty analysis implementation methods, covering the full spectrum of sensitivity analysis techniques, including operational products. Finally, the book outlines challenges and future prospects for implementation in earth observation modeling. Information provided in this book is of practical value to readers looking to understand the principles of sensitivity analysis in earth observation modeling, the level of scientific maturity in the field, and where the main limitations or challenges are in terms of improving our ability to implement such approaches in a wide range of applications. Readers will also be informed on the implementation of sensitivity/uncertainty analysis on operational products available at present, on global and continental scales. All of this information is vital in the selection process of the most appropriate sensitivity analysis method to implement. - Outlines challenges and future prospects of sensitivity analysis implementation in earth observation modeling - Provides readers with a roadmap for directing future efforts - Includes case studies with applications from different regions around the globe, helping readers to explore strengths and weaknesses of the different methods in earth observation modeling - Presents a step-by-step guide, providing the principles of each method followed by the application of variants, making the reference easy to use and follow

Structural Sensitivity Analysis and Optimization 2

Author : K. K. Choi
Publisher : Springer Science & Business Media
ISBN 13 : 0387273069
Total Pages : 336 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Structural Sensitivity Analysis and Optimization 2 by : K. K. Choi

Download or read book Structural Sensitivity Analysis and Optimization 2 written by K. K. Choi and published by Springer Science & Business Media. This book was released on 2006-12-22 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive numerical methods for computing design sensitivity are included in the text for practical application and software development. The numerical method allows integration of CAD-FEA-DSA software tools, so that design optimization can be carried out using CAD geometric models instead of FEA models. This capability allows integration of CAD-CAE-CAM so that optimized designs can be manufactured effectively.

Sensitivity Analysis in Linear Systems

Author : Assem Deif
Publisher : Springer Science & Business Media
ISBN 13 : 364282739X
Total Pages : 235 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Sensitivity Analysis in Linear Systems by : Assem Deif

Download or read book Sensitivity Analysis in Linear Systems written by Assem Deif and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: A text surveying perturbation techniques and sensitivity analysis of linear systems is an ambitious undertaking, considering the lack of basic comprehensive texts on the subject. A wide-ranging and global coverage of the topic is as yet missing, despite the existence of numerous monographs dealing with specific topics but generally of use to only a narrow category of people. In fact, most works approach this subject from the numerical analysis point of view. Indeed, researchers in this field have been most concerned with this topic, although engineers and scholars in all fields may find it equally interesting. One can state, without great exaggeration, that a great deal of engineering work is devoted to testing systems' sensitivity to changes in design parameters. As a rule, high-sensitivity elements are those which should be designed with utmost care. On the other hand, as the mathematical modelling serving for the design process is usually idealized and often inaccurately formulated, some unforeseen alterations may cause the system to behave in a slightly different manner. Sensitivity analysis can help the engineer innovate ways to minimize such system discrepancy, since it starts from the assumption of such a discrepancy between the ideal and the actual system.

Advances in Sensitivity Analysis and Parametric Programming

Author : Tomas Gal
Publisher : Springer Science & Business Media
ISBN 13 : 1461561035
Total Pages : 595 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Advances in Sensitivity Analysis and Parametric Programming by : Tomas Gal

Download or read book Advances in Sensitivity Analysis and Parametric Programming written by Tomas Gal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: The standard view of Operations Research/Management Science (OR/MS) dichotomizes the field into deterministic and probabilistic (nondeterministic, stochastic) subfields. This division can be seen by reading the contents page of just about any OR/MS textbook. The mathematical models that help to define OR/MS are usually presented in terms of one subfield or the other. This separation comes about somewhat artificially: academic courses are conveniently subdivided with respect to prerequisites; an initial overview of OR/MS can be presented without requiring knowledge of probability and statistics; text books are conveniently divided into two related semester courses, with deterministic models coming first; academics tend to specialize in one subfield or the other; and practitioners also tend to be expert in a single subfield. But, no matter who is involved in an OR/MS modeling situation (deterministic or probabilistic - academic or practitioner), it is clear that a proper and correct treatment of any problem situation is accomplished only when the analysis cuts across this dichotomy.

Sensitivity Analysis in Linear Regression

Author : Samprit Chatterjee
Publisher : John Wiley & Sons
ISBN 13 : 0470317426
Total Pages : 341 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Sensitivity Analysis in Linear Regression by : Samprit Chatterjee

Download or read book Sensitivity Analysis in Linear Regression written by Samprit Chatterjee and published by John Wiley & Sons. This book was released on 2009-09-25 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treats linear regression diagnostics as a tool for application of linear regression models to real-life data. Presentation makes extensive use of examples to illustrate theory. Assesses the effect of measurement errors on the estimated coefficients, which is not accounted for in a standard least squares estimate but is important where regression coefficients are used to apportion effects due to different variables. Also assesses qualitatively and numerically the robustness of the regression fit.

Estimands, Estimators and Sensitivity Analysis in Clinical Trials

Author : Craig Mallinckrodt
Publisher : CRC Press
ISBN 13 : 0429950055
Total Pages : 208 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Estimands, Estimators and Sensitivity Analysis in Clinical Trials by : Craig Mallinckrodt

Download or read book Estimands, Estimators and Sensitivity Analysis in Clinical Trials written by Craig Mallinckrodt and published by CRC Press. This book was released on 2019-12-23 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plans by explaining fundamental concepts using accessible language, providing technical details, real-world examples, and SAS and R code to implement analyses. The updated ICH guideline raises new analytic and cross-functional challenges for statisticians. Gaps between different communities have come to surface, such as between causal inference and clinical trialists, as well as among clinicians, statisticians, and regulators when it comes to communicating decision-making objectives, assumptions, and interpretations of evidence. This book lays out a path toward bridging some of these gaps. It offers  A common language and unifying framework along with the technical details and practical guidance to help statisticians meet the challenges  A thorough treatment of intercurrent events (ICEs), i.e., postrandomization events that confound interpretation of outcomes and five strategies for ICEs in ICH E9 (R1)  Details on how estimands, integrated into a principled study development process, lay a foundation for coherent specification of trial design, conduct, and analysis needed to overcome the issues caused by ICEs:  A perspective on the role of the intention-to-treat principle  Examples and case studies from various areas  Example code in SAS and R  A connection with causal inference  Implications and methods for analysis of longitudinal trials with missing data Together, the authors have offered the readers their ample expertise in clinical trial design and analysis, from an industrial and academic perspective.

Structural Sensitivity Analysis and Optimization 1

Author : Kyung K. Choi
Publisher : Springer Science & Business Media
ISBN 13 : 0387271694
Total Pages : 457 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Structural Sensitivity Analysis and Optimization 1 by : Kyung K. Choi

Download or read book Structural Sensitivity Analysis and Optimization 1 written by Kyung K. Choi and published by Springer Science & Business Media. This book was released on 2006-12-30 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive numerical methods for computing design sensitivity are included in the text for practical application and software development. The numerical method allows integration of CAD-FEA-DSA software tools, so that design optimization can be carried out using CAD geometric models instead of FEA models. This capability allows integration of CAD-CAE-CAM so that optimized designs can be manufactured effectively.

Missing Data in Longitudinal Studies

Author : Michael J. Daniels
Publisher : CRC Press
ISBN 13 : 1420011189
Total Pages : 324 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Missing Data in Longitudinal Studies by : Michael J. Daniels

Download or read book Missing Data in Longitudinal Studies written by Michael J. Daniels and published by CRC Press. This book was released on 2008-03-11 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing from the authors' own work and from the most recent developments in the field, Missing Data in Longitudinal Studies: Strategies for Bayesian Modeling and Sensitivity Analysis describes a comprehensive Bayesian approach for drawing inference from incomplete data in longitudinal studies. To illustrate these methods, the authors employ

Sensitivity & Uncertainty Analysis, Volume 1

Author : Dan G. Cacuci
Publisher : CRC Press
ISBN 13 : 0203498798
Total Pages : 304 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Sensitivity & Uncertainty Analysis, Volume 1 by : Dan G. Cacuci

Download or read book Sensitivity & Uncertainty Analysis, Volume 1 written by Dan G. Cacuci and published by CRC Press. This book was released on 2003-05-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: As computer-assisted modeling and analysis of physical processes have continued to grow and diversify, sensitivity and uncertainty analyses have become indispensable investigative scientific tools in their own right. While most techniques used for these analyses are well documented, there has yet to appear a systematic treatment of the method based