Semisynthesis Of Bioactive Compounds And Their Biological Activities

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Semisynthesis of Bioactive Compounds and their Biological Activities

Author : Sasadhar Majhi
Publisher : Elsevier
ISBN 13 : 0443152705
Total Pages : 484 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Semisynthesis of Bioactive Compounds and their Biological Activities by : Sasadhar Majhi

Download or read book Semisynthesis of Bioactive Compounds and their Biological Activities written by Sasadhar Majhi and published by Elsevier. This book was released on 2023-11-25 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Semisynthesis of Bioactive Compounds and their Biological Activities explores the potential benefits of semisynthetic derivatives obtained from nature. Sections cover the natural distribution of parent compounds, semisynthesis and biological properties of semisynthetic derivatives, the applications of semisynthetic derivatives in diverse fields such as drug delivery, food production and medicine, an explanation of the current resistance mechanisms of antibiotics, clinical applications of semisynthetic analogues, the functions of plant alkaloids on human health, potential agricultural biotechnology in semisynthetic derivatives, and semisynthesis of natural products under greener conditions, this book provides a comprehensive resource on the topics presented. Sections include information about alternative sources of energy and superior greener technologies (microwave, sonochemistry), alternative reaction media (water, supercritical CO2, ionic liquids) and alternative eco-friendly catalysts (biocatalysts). This book will be an excellent resource for academicians, researchers and students focusing on synthesis as well as the biological community and industry professionals in drug development. - Focuses on the current resistance mechanisms of antibiotics, chemical derivatization of antibiotics, and clinical applications of semisynthetic derivatives. - Includes discussion of the semisynthesis of natural products using green tools, green solvents, and eco-friendly catalysts. - Illustrates the concept of toxicity, the merits of transition-metal-free reactions, and the semisynthesis of natural products by introducing the oxygen atom(s) under transition-metal-free conditions.

Terpenoids and Steroids

Author : K H Overton
Publisher : Royal Society of Chemistry
ISBN 13 : 1847557007
Total Pages : 571 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Terpenoids and Steroids by : K H Overton

Download or read book Terpenoids and Steroids written by K H Overton and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Water Extraction of Bioactive Compounds

Author : Herminia Dominguez
Publisher : Elsevier
ISBN 13 : 0128096152
Total Pages : 486 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Water Extraction of Bioactive Compounds by : Herminia Dominguez

Download or read book Water Extraction of Bioactive Compounds written by Herminia Dominguez and published by Elsevier. This book was released on 2017-09-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Author : Goutam Brahmachari
Publisher : CRC Press
ISBN 13 : 9781032099132
Total Pages : 584 pages
Book Rating : 4.0/5 (991 download)

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Book Synopsis Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds by : Goutam Brahmachari

Chemical and Biological Synthesis

Author : Nick J Westwood
Publisher : Royal Society of Chemistry
ISBN 13 : 178801507X
Total Pages : 317 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Chemical and Biological Synthesis by : Nick J Westwood

Download or read book Chemical and Biological Synthesis written by Nick J Westwood and published by Royal Society of Chemistry. This book was released on 2018-08-16 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : John Wiley & Sons
ISBN 13 : 3527337946
Total Pages : 544 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Bioactive Natural Products by : Goutam Brahmachari

Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by John Wiley & Sons. This book was released on 2015-03-23 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein multidisziplinärer Überblick über die aktuellen Themen und Zukunftstrends in der Erforschung von Naturstoffen mit Schwerpunkt auf pharmazeutischen und medizinischen Anwendungen.

Macrocycles in Drug Discovery

Author : Jeremy I Levin
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737010
Total Pages : 526 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Macrocycles in Drug Discovery by : Jeremy I Levin

Download or read book Macrocycles in Drug Discovery written by Jeremy I Levin and published by Royal Society of Chemistry. This book was released on 2015 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides a comprehensive resource for postgraduate students and for scientists in academia or industry wanting to learn topics outside their own areas of expertise.

Biological Potential and Medical Use of Secondary Metabolites

Author : Ana M. L Seca
Publisher : MDPI
ISBN 13 : 3039211870
Total Pages : 284 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Biological Potential and Medical Use of Secondary Metabolites by : Ana M. L Seca

Download or read book Biological Potential and Medical Use of Secondary Metabolites written by Ana M. L Seca and published by MDPI. This book was released on 2019-07-26 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue.

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : World Scientific
ISBN 13 : 9814335371
Total Pages : 695 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Bioactive Natural Products by : Goutam Brahmachari

Download or read book Bioactive Natural Products written by Goutam Brahmachari and published by World Scientific. This book was released on 2012 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Biochemical Targets of Plant Bioactive Compounds

Author : Gideon Polya
Publisher : CRC Press
ISBN 13 : 0203013719
Total Pages : 864 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Biochemical Targets of Plant Bioactive Compounds by : Gideon Polya

Download or read book Biochemical Targets of Plant Bioactive Compounds written by Gideon Polya and published by CRC Press. This book was released on 2003-05-15 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.

The Role of Natural Products in Drug Discovery

Author : J. Mulzer
Publisher : Springer Science & Business Media
ISBN 13 : 3662040425
Total Pages : 363 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis The Role of Natural Products in Drug Discovery by : J. Mulzer

Download or read book The Role of Natural Products in Drug Discovery written by J. Mulzer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Author : Goutam Brahmachari
Publisher : CRC Press
ISBN 13 : 1439891672
Total Pages : 586 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds by : Goutam Brahmachari

Download or read book Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds written by Goutam Brahmachari and published by CRC Press. This book was released on 2013-02-20 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure–activity relationships.

Plant Functional Genomics

Author : Erich Grotewold
Publisher : Springer Science & Business Media
ISBN 13 : 1592594131
Total Pages : 443 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Plant Functional Genomics by : Erich Grotewold

Download or read book Plant Functional Genomics written by Erich Grotewold and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional genomics is a young discipline whose origin can be traced back to the late 1980s and early 1990s, when molecular tools became available to determine the cellular functions of genes. Today, functional genomics is p- ceived as the analysis, often large-scale, that bridges the structure and organi- tion of genomes and the assessment of gene function. The completion in 2000 of the genome sequence of Arabidopsis thaliana has created a number of new and exciting challenges in plant functional genomics. The immediate task for the plant biology community is to establish the functions of the approximately 25,000 genes present in this model plant. One major issue that will remain even after this formidable task is c- pleted is establishing to what degree our understanding of the genome of one model organism, such as the dicot Arabidopsis, provides insight into the or- nization and function of genes in other plants. The genome sequence of rice, completed in 2002 as a result of the synergistic interaction of the private and public sectors, promises to significantly enrich our knowledge of the general organization of plant genomes. However, the tools available to investigate gene function in rice are lagging behind those offered by other model plant systems. Approaches available to investigate gene function become even more limited for plants other than the model systems of Arabidopsis, rice, and maize.

Production of Biomass and Bioactive Compounds Using Bioreactor Technology

Author : Kee-Yoeup Paek
Publisher : Springer
ISBN 13 : 9401792232
Total Pages : 708 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Production of Biomass and Bioactive Compounds Using Bioreactor Technology by : Kee-Yoeup Paek

Download or read book Production of Biomass and Bioactive Compounds Using Bioreactor Technology written by Kee-Yoeup Paek and published by Springer. This book was released on 2014-09-30 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. This book emphasizes on the fundamental topics like designing of bioreactors for plant cell and organ cultures, various types of bioreactors including stirred tank, airlift, photo-bioreactor, disposable bioreactor used for plant cell and organ cultures and the advantages and disadvantages of bioreactor cultures. Various strategies for biomass production and metabolite accumulation have been discussed in different plant systems including Korean/Chinese ginseng, Siberian ginseng, Indian ginseng, Echinacea, St. John’s wort, Noni, Chinese licorice, Caterpillar fungus and microalgae. Researches on the industrial application of plant cells and organs with future prospects as well as the biosafety of biomass produced in bioreactors are also described. The topics covered in this book, such as plant cell and organ cultures, hairy roots, bioreactors, bioprocess techniques, will be a valuable reference for plant biotechnologists, plant biologists, pharmacologists, pharmacists, food technologists, nutritionists, research investigators of healthcare industry, academia, faculty and students of biology and biomedical sciences. The multiple examples of large-scale applications of cell and organ cultures will be useful and significant to industrial transformation and real commercialization.

Bioactive Compounds from Natural Sources

Author : Corrado Tringali
Publisher : CRC Press
ISBN 13 : 0203212312
Total Pages : 704 pages
Book Rating : 4.2/5 (32 download)

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Book Synopsis Bioactive Compounds from Natural Sources by : Corrado Tringali

Download or read book Bioactive Compounds from Natural Sources written by Corrado Tringali and published by CRC Press. This book was released on 2003-09-02 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.

Marine Bioactive Compounds

Author : Maria Hayes
Publisher : Springer Science & Business Media
ISBN 13 : 1461412471
Total Pages : 239 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Marine Bioactive Compounds by : Maria Hayes

Download or read book Marine Bioactive Compounds written by Maria Hayes and published by Springer Science & Business Media. This book was released on 2011-11-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim and scope of this book is to highlight the sources, isolation, characterization and applications of bioactive compounds from the marine environment and to discuss how marine bioactive compounds represent a major market application in food and other industries. It discusses sustainable marine resources of macroalgal origin and gives examples of bioactive compounds isolated from these and other resources, including marine by-product and fisheries waste streams. In addition, it looks at the importance of correct taxonomic characterization.

Bioactive Compounds in Underutilized Fruits and Nuts

Author : Hosakatte Niranjana Murthy
Publisher : Springer
ISBN 13 : 9783030301811
Total Pages : 0 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Bioactive Compounds in Underutilized Fruits and Nuts by : Hosakatte Niranjana Murthy

Download or read book Bioactive Compounds in Underutilized Fruits and Nuts written by Hosakatte Niranjana Murthy and published by Springer. This book was released on 2020-04-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Reference Work provides a comprehensive overview of bioactive compounds found in underutilized fruits and nuts around the world and it elucidates their pharmacological, biological and health effects. In this book, readers will learn about the potential applications of bioactive molecules presented in several underutilized fruits and nuts rich in carbohydrates, lipids, fats, proteins, polyphenols, carotenoids, vitamins, organic acids, and volatile compounds. Readers will also discover more about the nutraceutical importance of these underutilized crops, and will also find specific case studies of the therapeutic potential of undertilized fruits and nuts. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from students and researchers to healthcare and industry professionals interested in plant biotechnology, biology, pharmacology and food engineering.