Scorpion Venoms

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Author :
Publisher : Springer
ISBN 13 : 9789400766471
Total Pages : 550 pages
Book Rating : 4.7/5 (664 download)

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Book Synopsis Scorpion Venoms by : P. Gopalakrishnakone

Download or read book Scorpion Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2021-01-14 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Scorpion Venoms

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Author :
Publisher : Springer
ISBN 13 : 9789400764033
Total Pages : 575 pages
Book Rating : 4.7/5 (64 download)

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Book Synopsis Scorpion Venoms by : P. Gopalakrishnakone

Download or read book Scorpion Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-21 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scorpions have fascinated humans for a long time, first and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms. This volume of the Toxinology handbook series covers all those aspects. The subjects are divided into seven sections starting with an introduction to the general aspects of scorpion biology and ecology, followed by the description of the “envenomation” pathophysiology, pharmacokinetics, and pharmacodynamics of venoms and their complex interactions with the immune system. The future of anti-scorpion venom therapy is then covered in two chapters dedicated to alternatives to the century-old techniques currently used to produce “anti-venoms”. The next section presents a world tour of “scorpionism” and dangerous scorpion species and their impact on human health. It is worth remembering that envenomation due to scorpion stings is a substantial health hazard in Asian, Middle Eastern, African, and Latin American countries, with over one million people stung by scorpions every year, resulting in more than 3,000 deaths. Species-centered overviews of “scorpion venoms” are presented in the next section, after which a section details the two main types of “scorpion toxins”. The last section covers high-throughput transcriptome and proteome screenings now known as “venomics”. This volume provides chapters that are accessible to a broad audience, yet also contains the depth of knowledge and detail which makes it of interest to experts in the field. Readers of this reference work will leave well informed on the current state of the art of scorpion venom research.

Greek Fire, Poison Arrows, and Scorpion Bombs

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Author :
Publisher : Penguin
ISBN 13 : 1590203747
Total Pages : 319 pages
Book Rating : 4.5/5 (92 download)

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Book Synopsis Greek Fire, Poison Arrows, and Scorpion Bombs by : Adrienne Mayor

Download or read book Greek Fire, Poison Arrows, and Scorpion Bombs written by Adrienne Mayor and published by Penguin. This book was released on 2008-12-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A comprehensive look at WMD's antecedents, from flamethrowers of the Peloponnesian War to plague-bearing booby traps.... Rich and entertaining." -Newsweek Featuring a new introduction by the author. Flamethrowers, poison gases, incendiary bombs, the large-scale spreading of disease... are these terrifying agents and implements of warfare modern inventions? Not by a long shot. Weapons of biological and chemical warfare have been in use for thousands of years, and Greek Fire, Poison Arrows & Scorpion Bombs, Adrienne Mayor's fascinating exploration of the origins of biological and unethical warfare draws extraordinary connections between the mythical worlds of Hercules and the Trojan War, the accounts of Herodotus and Thucydides, and modern methods of war and terrorism. Greek Fire, Poison Arrows & Scorpion Bombs will catapult readers into the dark and fascinating realm of ancient war and mythic treachery-and their devastating consequences.

Deadly Scorpion Sting!

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Author :
Publisher : Bearport Publishing
ISBN 13 : 1642804053
Total Pages : 28 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Deadly Scorpion Sting! by : Kevin Blake

Download or read book Deadly Scorpion Sting! written by Kevin Blake and published by Bearport Publishing. This book was released on 2018-08-01 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep in the jungles of Thailand, Gareth Pike awoke one sunny morning in 2007. As he was getting dressed, he reached down to grab a pair of shorts off his floor. Suddenly, Gareth felt a horrible stinging pain in his thumb. Then he spotted a deadly black scorpion scurrying away. “I was in dreadful pain,” said Gareth. Would he survive his encounter with a venomous scorpion? Learn all about venomous scorpions in this engrossing new narrative nonfiction book for young readers. It’s packed with exciting wildlife encounters, cutting-edge science, and loads of info about venom and its deadly effects.

Clinical Toxinology in Asia Pacific and Africa

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Author :
Publisher : Springer
ISBN 13 : 9789400763852
Total Pages : 636 pages
Book Rating : 4.7/5 (638 download)

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Book Synopsis Clinical Toxinology in Asia Pacific and Africa by : P. Gopalakrishnakone

Download or read book Clinical Toxinology in Asia Pacific and Africa written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-03-12 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical toxinologic conditions are becoming increasingly frequent, more so than is generally recognized. The conditions comprise of clinical aspects such as the diagnosis, management, and prevention of snakebite envenoming, scorpion sting, mushroom toxins, plant toxins, and other natural toxins. Clinical toxinology also deals with the ecology, epidemiology, regional differences, and varieties of fauna accounting for different envenoming manifestations. This handbook includes 30 chapters addressing various topics on clinical toxinology such as the epidemiology and management of snakebites in different Asian and African countries, disability following snakebite, effect of snake venoms on hemostasis, socioeconomic aspects of snakebites, therapeutic application of snake venom, scorpion sting in the Middle East, jellyfish sting, etc. These titles are written by experts currently working in the subspecialty, many of whom have first-hand experience in the relevant research fields. In virtually all the topics, appropriate illustrations are provided to simplify comprehension including tables, figures and pictures. This reference work on Clinical Toxinology in Asia Pacific and Africa, in the Toxinology handbook series, is designed to keep readers abreast with new knowledge and experience in toxinology regionally and globally. Toxinologists, researchers, scientists, and experts in this field from various working areas considered it necessary to collect all the aspects of clinical toxinology in a single, handy handbook. This can be used by medical students, postgraduate students, general practitioners, specialists in internal medicine, critical care physicians, emergency physicians, and anesthetists worldwide.

Scorpion Venoms—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481631381
Total Pages : 27 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Scorpion Venoms—Advances in Research and Application: 2012 Edition by :

Download or read book Scorpion Venoms—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scorpion Venoms—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Scorpion Venoms in a compact format. The editors have built Scorpion Venoms—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Scorpion Venoms in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Scorpion Venoms—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Arthropod Venom Components and Their Potential Usage

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Author :
Publisher : MDPI
ISBN 13 : 3039285408
Total Pages : 404 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Arthropod Venom Components and Their Potential Usage by : Katsuhiro Konno

Download or read book Arthropod Venom Components and Their Potential Usage written by Katsuhiro Konno and published by MDPI. This book was released on 2020-03-25 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.

Handbook of Biologically Active Peptides

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Author :
Publisher : Elsevier
ISBN 13 : 0080463797
Total Pages : 1640 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar. *Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Venom Genomics and Proteomics

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Author :
Publisher : Springer
ISBN 13 : 9789400764156
Total Pages : 0 pages
Book Rating : 4.7/5 (641 download)

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Book Synopsis Venom Genomics and Proteomics by : P. Gopalakrishnakone

Download or read book Venom Genomics and Proteomics written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-10-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Ion Channel Factsbook

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Author :
Publisher : Academic Press
ISBN 13 : 9780080535197
Total Pages : 426 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Ion Channel Factsbook by :

Download or read book Ion Channel Factsbook written by and published by Academic Press. This book was released on 1995-11-16 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. Nomenclature Expression Sequence analyses Structure and function Electrophysiology Pharmacology Information retrieval

Venoms to Drugs

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782624376
Total Pages : 320 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Venoms to Drugs by : Glenn F. King

Download or read book Venoms to Drugs written by Glenn F. King and published by Royal Society of Chemistry. This book was released on 2015-01-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Venom

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Author :
Publisher : Smithsonian Institution
ISBN 13 : 1588344541
Total Pages : 207 pages
Book Rating : 4.5/5 (883 download)

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Book Synopsis Venom by : Ronald Jenner

Download or read book Venom written by Ronald Jenner and published by Smithsonian Institution. This book was released on 2017-10-17 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Venom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.

Arthropod Venoms

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642455018
Total Pages : 998 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Arthropod Venoms by : S. Bettini

Download or read book Arthropod Venoms written by S. Bettini and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthropod venoms have received much attention and have played an important role in folklore and medicine since ancient times. Scorpion envenomation, "tarant ism," bee and wasp stings are among those subjects about which most has been speculated and written in the past. In the last 50 years or so, a great number of scientific papers have been devoted to arthropod venoms, but only a few volumes have been designed to collect this rapidly increasing material, and these are not recent. Of late, the chemistry and mode of action of several arthropod venoms have been thoroughly studied, and some of these substances will probably be used as pharmacological tools and also as therapeutic agents. The aim of the present volume is to collect in manual form new information as well as the old notions on arthropod venoms. Even though it was our intention to present a volume on arthropod venoms, and not on venomous arthropods, inevitably we were forced to include information on venom-producing organisms as well. We assumed, in fact, that those scientists for whom the present manual is primarily intended (biochemists, particularly com parative biochemists, and pharmacologists) should be familiar with the biologic elements concerning the venom-producing species; which should show them how important it is to operate in close collaboration with biologists specialized in venomous arthropod systematics and biology.

Venoms to Drugs

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737878
Total Pages : 320 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Venoms to Drugs by : Glenn F. King

Download or read book Venoms to Drugs written by Glenn F. King and published by Royal Society of Chemistry. This book was released on 2015-01-27 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Protein and Peptide Nanoparticles for Drug Delivery

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Author :
Publisher : Academic Press
ISBN 13 : 012802870X
Total Pages : 396 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Protein and Peptide Nanoparticles for Drug Delivery by :

Download or read book Protein and Peptide Nanoparticles for Drug Delivery written by and published by Academic Press. This book was released on 2015-03-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Steve Backshall's Venom

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Author :
Publisher : Bloomsbury Publishing
ISBN 13 : 1472930274
Total Pages : 160 pages
Book Rating : 4.4/5 (729 download)

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Book Synopsis Steve Backshall's Venom by : Steve Backshall

Download or read book Steve Backshall's Venom written by Steve Backshall and published by Bloomsbury Publishing. This book was released on 2017-09-21 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: TV presenter Steve Backshall needs no introduction following his performances on TV series such as Deadly 60 and Lost Land of ... This is a reformatted, redesigned edition of a popular title. Poison is an everyday part of the animal world, and an essential tool for hunting and defence. A wide variety of insects, reptiles and amphibians use toxins to subdue their prey or to stop becoming prey to another predator. Even some mammals and birds resort to poison as a means of securing a meal or deterring attack! From species such as the King Cobra, Lionfish, Fat-tail Scorpion and Poison Dart-frog to the diminutive but lethal Black Widow Spider, the author takes a fascinating look at the different types of natural venoms. On a tour of the world's continents, he looks at over 60 of the most venomous creatures, describing their main characteristics and explaining how they administer their venom and what its effects are. Stunning colour photographs and exciting accounts of Steve's own encounters with some of these animals bring the world of natural venom alive.

Management of Wilderness and Environmental Emergencies

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Author :
Publisher :
ISBN 13 :
Total Pages : 682 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Management of Wilderness and Environmental Emergencies by : Paul S. Auerbach

Download or read book Management of Wilderness and Environmental Emergencies written by Paul S. Auerbach and published by . This book was released on 1983 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: