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Author : Marc De Schrijver
Publisher :
ISBN 13 : 9789400923867
Total Pages : 224 pages
Book Rating : 4.9/5 (238 download)
Download or read book Scintigraphy of Inflammation with Nanometer-Sized Colloidal Tracers written by Marc De Schrijver and published by . This book was released on 1990-02-28 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marc De Schrijver
Publisher : Springer Science & Business Media
ISBN 13 : 9400923856
Total Pages : 214 pages
Book Rating : 4.4/5 (9 download)
Download or read book Scintigraphy of Inflammation with Nanometer-sized Colloidal Tracers written by Marc De Schrijver and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work presented here is based upon contact with excellent scientists who did not measure their time sparingly to be of assistance. It has also benefited from the infrastructure some col leagues made available to me, and without which considerable delays and expenditure would have been unavoidable. In this respect, I am particularly indebted to a number of people. Dr. J. Abramovici, Professor S. Orloff and Professor R. Fridrich reviewed my data critically and gave me access to their Insti tutes, enabling me to collect the clinical evi dence required to complete this work. The latter benefited also from the efforts of Dr. K. Streule who supervised the cross-over study upon which the final conclusions have been based. Dr. R. Senekowitsch and her staff were of inva luable help with the animal experimental data and was, together with Professor H. Kriegel, kind enough to enable me to complete this particular part. Dr. H.L. Chia's laboratory data provided me with the possibility to widen the radiopharmaceu tical aspects of the theme under discussion. I am also indebted to Dr. K.J. Panek for personal com ments regarding the radiation dosimetry of lll- v vi SCINTIGRAPHY OF INFLAMMATION labelled leukocytes.
Author : P.H. Cox
Publisher : Springer Science & Business Media
ISBN 13 : 9401149909
Total Pages : 232 pages
Book Rating : 4.4/5 (11 download)
Download or read book The Imaging of Infection and Inflammation written by P.H. Cox and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite 50 years of antibiotics, infection remains a major source of both morbidity and mortality. Immunosuppression, either secondary to drugs in transplant recipients or secondary to HIV, has expanded the number of microorganisms that are known to be pathogenic in man. Imaging of infection has a vital role both in the initial diagnosis and in the continuing management of patients with infection or suspected infection. Functional imaging using nuclear medicine techniques has a unique role to play in identifying sites of infection in a wide range of patients with varying clinical conditions. This book, written by a series of experts not just in the fields of nuclear medicine but also infectious disease and radiology, discusses the role of nuclear medicine in three parts: a review of the pathophysiology of infection; a technical description of those nuclear medicine techniques which can be used in imaging infection; an extensive systematic review including thoracic, abdominal and orthopaedic infection as well as a special section on the acutely ill patient, the immunosuppressed patient and the patient with pyrexia of unknown origin. This book will be of interest to all clinicians looking after patients with infection and who need to use imaging techniques. It will also be of use to radiologists and nuclear medicine physicians who will be using these techniques clinically.
Author : K. E. Britton
Publisher : Springer
ISBN 13 : 1489933565
Total Pages : 757 pages
Book Rating : 4.4/5 (899 download)
Download or read book Clinical Nuclear Medicine written by K. E. Britton and published by Springer. This book was released on 2013-11-11 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine is the bridge between a particular clinical problem and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book to approach the subject from a clinical standpoint, including where necessary relevant physiological material. There exist many excellent texts which cover the basic science and technology of nuclear medicine. We have, therefore, severely limited our coverage of these aspects of the subject to matters which we felt to be essential, particularly those which have been less well covered in other texts - for example, the contents of Chapter 21 on Quantitation by Royal and McNeil. Similarly, we have included at the end of some chapters descriptions of particular techniques where we and the authors felt that it would be helpful. In order to emphasize the clinical approach of this book we have inverted the traditional sequence of material in chapters, presenting the clinical problems first in each instance.
Author : J.C Baron
Publisher : Springer Science & Business Media
ISBN 13 : 9401135282
Total Pages : 206 pages
Book Rating : 4.4/5 (11 download)
Download or read book Brain Dopaminergic Systems: Imaging with Positron Tomography written by J.C Baron and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J.C. Baron D. Comar L. Farde J.L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.
Author : Jorg Kreuter
Publisher : CRC Press
ISBN 13 : 1498710565
Total Pages : 366 pages
Book Rating : 4.4/5 (987 download)
Download or read book Colloidal Drug Delivery Systems written by Jorg Kreuter and published by CRC Press. This book was released on 2014-07-22 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a single-source of reviews for all the important colloidal drug delivery systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments. Over 1000 bibliographic citations, as well as tables, drawings, equations and photographs, are provided. Arranged in order of increasing physical complexity, this work ana
Author : Giuseppe Gobbi
Publisher : John Libbey Eurotext
ISBN 13 : 9780861965373
Total Pages : 402 pages
Book Rating : 4.9/5 (653 download)
Download or read book Epilepsy and Other Neurological Disorders in Coeliac Disease written by Giuseppe Gobbi and published by John Libbey Eurotext. This book was released on 1997 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coeliac disease may be manifested with gastrointestinal symptoms, or be latent. It may also be present with dermatitis herpetiformis, dental enamel defects or neurological disorders - especially epilepsy. In the case of the latter symptoms, these appear mostly in relation to occipital seizures, frequently intractable. This book examines these and other neurological manifestations.
Author : Francisco José H.N. Braga
Publisher : Springer Science & Business Media
ISBN 13 : 1461511798
Total Pages : 282 pages
Book Rating : 4.4/5 (615 download)
Download or read book Nuclear Medicine in Tropical and Infectious Diseases written by Francisco José H.N. Braga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: "More than half of the world's population is at risk of the tropical diseases malaria, leprosy, schistosomiasis, lymphatic filariasis, onchocerciasis, Chagas' disease, African trypanosomiasis and leishmaniasis and half a billion are infected with at least one of these diseases". J. H. F. Remme, World Health Organisation, 1993. "If it is true that science is not limited by frontiers and all research Institutions then belong to mankind, so it is natural for each Institution to be responsible for the problems of those who live in the geographic area under its influence. There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology. It is the duty of each Institution to study the particular aspects concerning its geographic region, as missing links of the chain of universal knowledge may be found there." H. L. de Oliveira, fonner Rector of the University ofSiio Paulo, 1967. "Nuclear Medicine is cost effective, especially in the developing countries. ( ... ).
Author : Max Donbrow
Publisher : CRC Press
ISBN 13 : 1000087026
Total Pages : 358 pages
Book Rating : 4.0/5 ( download)
Download or read book Microcapsules and Nanoparticles in Medicine and Pharmacy written by Max Donbrow and published by CRC Press. This book was released on 2020-04-15 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1992: This book provides a comprehensive look at the design and production of microcapsules, microspheres, and nanoparticles. It discusses the diverse aspects and skills that must be mastered to prepare and test products that will work correctly and be clinically acceptable for human or animal use.
Author : B.M. Mazoyer
Publisher : Springer Science & Business Media
ISBN 13 : 9401116202
Total Pages : 270 pages
Book Rating : 4.4/5 (11 download)
Download or read book PET Studies on Amino Acid Metabolism and Protein Synthesis written by B.M. Mazoyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? These questions have been addressed for a long time and no satisfactory answer has yet been given. This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.
Author : G. Stöcklin
Publisher : Springer Science & Business Media
ISBN 13 : 9780792323402
Total Pages : 210 pages
Book Rating : 4.3/5 (234 download)
Download or read book Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects written by G. Stöcklin and published by Springer Science & Business Media. This book was released on 1993-06-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals. Of the several hundred products which have been labelled with positron emitters during the past two decades about 35 are presently considered to be of major interest. The time for a state-of-the-art review is right, since this field has advanced over the past fifteen years to reach a level where guidelines can now be suggested. Chapters of this book deal with each of the main methodological aspects of the chemistry needed to develop an effective radiopharmaceutical, namely radionuclide production, automation and metabolite analysis. A further chapter on QA/QC is written by a broadly-based expert group and is meant to provide a guideline and a base for future monographs and regulations on major PET radiopharmaceuticals of today. This book will help the increasing numbers of scientists who are now entering the field of PET to appreciate the methodological aspects that are normally addressed by chemists in relation to PET radiopharmaceuticals; it provides many useful practical guidelines and will promote early success in their own endeavours, since these will often necessarily begin by establishing chemical methodology of the kind discussed here.
Author : Mrinal K. Dewanjee
Publisher : Springer Science & Business Media
ISBN 13 : 1461535085
Total Pages : 627 pages
Book Rating : 4.4/5 (615 download)
Download or read book Radioiodination: Theory, Practice, and Biomedical Applications written by Mrinal K. Dewanjee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Author : C. Kessler
Publisher : Springer Science & Business Media
ISBN 13 : 9400905815
Total Pages : 307 pages
Book Rating : 4.4/5 (9 download)
Download or read book Clinical Application of Radiolabelled Platelets written by C. Kessler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.
Author : P.H. Cox
Publisher : Springer Science & Business Media
ISBN 13 : 9401102295
Total Pages : 253 pages
Book Rating : 4.4/5 (11 download)
Download or read book The Clinical Applications of SPET written by P.H. Cox and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past nuclear medicine has tended to develop in cycles governed by the development of new radiopharmaceuticals followed or preceded by advances in instrumentation. The development of alternative techniques, such as X-Ray Computer Tomography, NMR Imaging and Ultrasound have also had a stimulating effect and pointed the way to new developments. The development of Positron Emission Tomography, while in itself of limited application because of high costs involved, provided a great deal of information which led to the development of new organ or disease specific, single photon emitting radiopharmaceuticals together with tomographic Gamma cameras, whereby detailed information on the biodistribution of the reagents could be obtained with accurate spatial resolution presented in a form suitable for comparison with the other imaging modalities. This technology, known as Single Photon Emission (Computer) Tomography (SPECT or SPET, as the mood takes you) is now an essential tool in nuclear medicine. The volume presents a basic guideline to the technology involved and discusses the application of the method to the investigation of various anatomical regions of the body. The book is an aide mémoire to the routine practitioner and a source of information for other medical specialists.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1024 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.:/5 (319 download)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1990 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 1196 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1988 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
