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Role Of Glucokinase Expressions In Diabetes Mellitus
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Book Synopsis Role of Glucokinase Expressions in Diabetes Mellitus by : Shankaraiah Puligilla
Download or read book Role of Glucokinase Expressions in Diabetes Mellitus written by Shankaraiah Puligilla and published by LAP Lambert Academic Publishing. This book was released on 2018-12-17 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is one of the important book for knowing about the Glucokinase... The book has covered the Mechanism and functions of the glucokinase in controlling of the Blood glucose. The book also covered the Causes for Glucokinse inactiveness and the effect of different drugs. The important thing is the diet and drugs influences on the glucokinase activity and controlling of the glucose levels in the body. Glucokinase(EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver, pancreas, gut and brain of humans and most other vertebrates. In each of these organs it plays an important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose, such as occur after a meal or when fasting. Mutations of the genefor this enzyme can cause unusual forms of diabetes or hypoglycemia.
Author :Franz M. Matschinsky Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805577443 Total Pages :417 pages Book Rating :4.8/5 (55 download)
Book Synopsis Glucokinase and Glycemic Diseases by : Franz M. Matschinsky
Download or read book Glucokinase and Glycemic Diseases written by Franz M. Matschinsky and published by Karger Medical and Scientific Publishers. This book was released on 2004 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The glucose-phosphorylating enzyme glucokinase (also known as hexokinase IV) plays a preeminent role as a glucose sensor and regulatory metabolic enzyme. The implications of this central position of glucokinase for the understanding and treatment of diabetes mellitus are far reaching. This book addresses the molecular and human genetic, as well as the physiological-chemical and pharmacological aspects of the role glucokinase plays in glucose homeostasis and diseases of glucose metabolism, and how the enzyme serves as the drug target for the treatment of diabetes mellitus. The collection of assays by a team of internationally renowned authors includes basic science chapters dealing with the enzymology, structure and the kinetics of hexokinases, essays describing the biochemical genetics of glucokinase-linked hypo- and hyperglycemia syndromes, and papers that discuss the diverse roles of the enzyme in a variety of tissues. Finally, the book contains the latest information on the recently discovered class of weight drugs that activate glucokinase (i.e. glucokinase activators or GKAs). This volume is of great interest to basic and clinical diabetes researchers, geneticists, biochemists, physiologists and pharmacologists.
Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel
Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
Book Synopsis The Genetic Landscape of Diabetes by : Laura Dean
Download or read book The Genetic Landscape of Diabetes written by Laura Dean and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling
Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enzymes As Sensors by : Carol A. Fierke
Download or read book Enzymes As Sensors written by Carol A. Fierke and published by Academic Press. This book was released on 2017-04-07 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 589, the latest volume in the Methods in Enzymology series, focuses on enzymes as sensors. Contain contributions from leading authorities Informs and updates on all the latest developments in the field
Book Synopsis International Textbook of Diabetes Mellitus by : R. A. DeFronzo
Download or read book International Textbook of Diabetes Mellitus written by R. A. DeFronzo and published by John Wiley & Sons. This book was released on 2015-03-11 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.
Download or read book The Pancreatic Beta Cell written by and published by Academic Press. This book was released on 2014-02-20 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways
Book Synopsis Pediatric Type II Diabetes by : Grace Kim
Download or read book Pediatric Type II Diabetes written by Grace Kim and published by Elsevier Health Sciences. This book was released on 2018-12-04 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally considered an adult disorder, type 2 diabetes in children has been steadily increasing in the past several years. This easy-to-read reference presents a succinct overview of clinically-focused topics covering diagnosis, treatment, management, and complications of type 2 diabetes mellitus in pediatric patients. An ideal reference for both pediatric endocrinologists as well as pediatricians, it’s an excellent overview of this fast-changing and complex field. Covers clinical presentation, diagnostic criteria, screening, and other topics related to diagnosis. Discusses complications such as hypertension, retinopathy, depression, PCOS, fatty liver, and more. Includes information on medications, lifestyle interventions, and surgical treatment. Consolidates today’s available information and experience in this timely area into one convenient resource.
Book Synopsis Glucose Sensing by : Chris D. Geddes
Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.
Book Synopsis Type 2 Diabetes by : Anca Pantea Stoian
Download or read book Type 2 Diabetes written by Anca Pantea Stoian and published by BoD – Books on Demand. This book was released on 2021-09-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.
Book Synopsis Principles of Nutrigenetics and Nutrigenomics by : Raffaele De Caterina
Download or read book Principles of Nutrigenetics and Nutrigenomics written by Raffaele De Caterina and published by Academic Press. This book was released on 2019-09-22 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book
Book Synopsis Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus by :
Download or read book Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus written by and published by Academic Press. This book was released on 2013-12-24 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research. Written by experts in the field Informs on important topics related to the regulation of glucose homeostasis and the pathogenesis of diabetes mellitus, a field of intense research interest
Book Synopsis Teratocarcinomas and Embryonic Stem Cells by : Elizabeth J. Robertson
Download or read book Teratocarcinomas and Embryonic Stem Cells written by Elizabeth J. Robertson and published by Oxford University Press, USA. This book was released on 1987 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Basis of Pancreas Development and Function by : Joel F. Habener
Download or read book Molecular Basis of Pancreas Development and Function written by Joel F. Habener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is rapidly increasing in prevalence throughout both developed and developing countries. The social and economic burden of this disease is estimated to cost 14 billion dollars worldwide. In the USA alone, 15 million individuals are diabetic, nearly half of them unaware of their condition. Complications of diabetes mellitus are the leading causes for blindness, limb amputation and chronic renal failure and kidney transplantation in industrialized countries. Further, diabetes mellitus per se and the metabolic derangement associated with diabetes are important risk factors for cardiovascular disease. Diabetes, as defined by an elevated fasting blood glucose level is presently subdivided in etiologically distinct groups. The most prevalent being type 2 (adult onset) diabetes characterized by insulin resistance and failure of the ~-cell to supply insulin in amounts sufficient to meet the body's needs. Type 1 (juvenile) diabetes, most commonly with an onset during childhood and adolescence, is caused by an auto-immune destruction of the pancreatic ~-cells. The causations of both type 1 and type 2 diabetes involve a combination of complex genetic traits and environmental influences. A third category are the mature onset diabetes of the young (MODY). This comparatively small group of patients (-10% of diabetes) presents relative early in life «30 years of age) compared to the more common late onset type 2 diabetes.
Book Synopsis Williams Textbook of Endocrinology by : Robert Hardin Williams
Download or read book Williams Textbook of Endocrinology written by Robert Hardin Williams and published by W B Saunders Company. This book was released on 2003 with total page 1927 pages. Available in PDF, EPUB and Kindle. Book excerpt: The state-of-the-art, tenth edition of endocrinology's classic text bridges the gap between basic science and endocrinology clinical practice. Thoroughly revised and updated, it includes new material on the thyroid and diabetes mellitus to reflect today's explosive increase in knowledge. Written by an outstanding team of authors, the 10th edition features numerous new authors who provide fresh perspectives. Presents a wealth of clinical information in a manageable size and format Contributors are at the forefronts of their disciplines Serves as a bridge between basic science and clinical endocrinology Diabetes mellitus and it complications has been greatly expanded and now includes 3 separate chapters. 4 new chapters Two new editors provide a fresh perspective on the material Figures have been added to the Diabetes Mellitus chapters Much of the art has been revised and includes new algorithms in many chapters Access to abstracts is available through Medline With 71 expert contributors
Book Synopsis Diabetes Mellitus by : Derek LeRoith
Download or read book Diabetes Mellitus written by Derek LeRoith and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
