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Risking Antimicrobial Resistance
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Book Synopsis Risking Antimicrobial Resistance by : Carsten Strøby Jensen
Download or read book Risking Antimicrobial Resistance written by Carsten Strøby Jensen and published by Springer. This book was released on 2018-07-14 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial resistance (AMR) is predicted to be one of the greatest threats to public health in the twenty-first century. In this context, understanding the reasons why perceptions of antibiotic risk differ between different groups is crucial when it comes to tackling antibiotic misuse. This innovative volume gathers together chapters written by sociologists, psychologists and linguists with the common aim of examining the social factors that affect use of antibiotics among humans and animals. A unique focus on Denmark – one of the world’s most progressive countries when it comes to antibiotic regulation – as well as Europe more broadly, makes this book a valuable resource for regulatory deliberations on future antibiotic policy to effectively combat AMR.
Book Synopsis Antibiotic Resistance by : Adriel R. Bonilla
Download or read book Antibiotic Resistance written by Adriel R. Bonilla and published by Nova Biomedical Books. This book was released on 2009 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance is the ability of a micro-organism to withstand the effects of antibiotics. There are three mechanisms that can cause antibiotic resistance: prevention of interaction of drug with target, decreased uptake due to either an increased efflux or a decreased influx of the antimicrobial agent and enzymatic modification or destruction of the compound. In the past couple years, antibiotic resistance has become an increasing public health concern. Tuberculosis, gonorrhoea, malaria and childhood ear infections are just a few of the diseases that have become hard to treat with antibiotic drugs. This book addresses the concern that over the past few years, there has been a major rise in resistance to antibiotics among gram-negative bacteria. New antibacterial drugs with novel modes of actions are urgently required in order to fight against infection. Novel antibiotics such as linezolid, carbapenem ertapenem, daptomycin and gemifloxacin are examined in this book. The genetic approaches used in risk assessment of antibiotic resistance dissemination are looked at as well. Furthermore, this book discusses the present studies on the use of veterinary antibiotics in agriculture, on the occurrence of antibiotic compounds and resistant bacteria in soil and water and clearly demonstrates the need for further studies.
Book Synopsis Extending the Cure by : Ramanan Professor Laxminarayan
Download or read book Extending the Cure written by Ramanan Professor Laxminarayan and published by Routledge. This book was released on 2010-09-30 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309466520 Total Pages :173 pages Book Rating :4.3/5 (94 download)
Book Synopsis Combating Antimicrobial Resistance by : National Academies of Sciences, Engineering, and Medicine
Download or read book Combating Antimicrobial Resistance written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-08 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment. To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop.
Book Synopsis Antibiotic Resistance by : Institute of Medicine
Download or read book Antibiotic Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-10 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.
Book Synopsis Ethics and Drug Resistance: Collective Responsibility for Global Public Health by : Euzebiusz Jamrozik
Download or read book Ethics and Drug Resistance: Collective Responsibility for Global Public Health written by Euzebiusz Jamrozik and published by Springer. This book was released on 2021-08-21 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.
Book Synopsis Antimicrobial Resistance by : Institute of Medicine
Download or read book Antimicrobial Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 1998-06-13 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problemâ€"especially of multidrug resistanceâ€"in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.
Book Synopsis Antimicrobial Resistance by : J. Todd Weber
Download or read book Antimicrobial Resistance written by J. Todd Weber and published by Karger Medical and Scientific Publishers. This book was released on 2010-01-01 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preventing, controlling and treating drug-resistant infections is one of the major challenges in modern medicine. Antimicrobial Resistance goes beyond simple definitions and microbiological data to fully explore this rapidly changing area, describing evidence for effective interventions, costs, treatment strategies and directions for future research. Each chapter provides essential background and examines the evidence for an important aspect of prevention and control, treatment strategy or policy decision. Prevention and control strategies are analyzed for inappropriate antimicrobial use, fluoroquinolone-resistant organisms, health-care associated infections and parasitic diseases. Furthermore, treatment strategies for changing resistance patterns are explored for community-acquired pneumonia during an influenza pandemic and infections with community-associated MRSA, extended-spectrum beta-lactamase producing organisms and fungi. Data for policy making are presented in articles that detail the costs of antimicrobial-resistant infections in healthcare settings and the threat of resistance with the introduction of antiretroviral therapy for large populations in the developing world. These reviews show where interventions, surveillance and research will be most useful in the future. Antimicrobial Resistance is an invaluable contribution for infectious disease physicians and public health officials who are interested in the prevention of antimicrobial-resistant infections.
Book Synopsis Exposure, Risks, and Drivers of the Mobile Antimicrobial Resistance Genes in the Environment – a Global Perspective by : Abasiofiok Mark Ibekwe
Download or read book Exposure, Risks, and Drivers of the Mobile Antimicrobial Resistance Genes in the Environment – a Global Perspective written by Abasiofiok Mark Ibekwe and published by Frontiers Media SA. This book was released on 2022-01-19 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Risk Profile on Antimicrobial Resistance Transmissible from Food Animals to Humans by : Pieternella Laura Geenen
Download or read book Risk Profile on Antimicrobial Resistance Transmissible from Food Animals to Humans written by Pieternella Laura Geenen and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Global Antimicrobial Resistance Surveillance System by : World Health Organization
Download or read book Global Antimicrobial Resistance Surveillance System written by World Health Organization and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In May 2015, the Sixty-eighth World Health Assembly adopted the Global action plan on antimicrobial resistance, which reflects the global consensus that AMR poses a profound threat to human health. One of the five strategic objectives of the Global action plan is to strengthen the evidence base through enhanced global surveillance and research. The Global Antimicrobial Resistance Surveillance System (GLASS) has been developed to facilitate and encourage a standardized approach to AMR surveillance globally and in turn support the implementation of the Global action plan on antimicrobial resistance. This manual addresses the early phase of implementation of GLASS, focussing on surveillance of resistance in common human bacterial pathogens. The intended readership of this publication is public health professionals and health authorities responsible for national AMR surveillance. It outlines the GLASS standards and describes the road map for implementation of the system between 2015 and 2019. Further development of GLASS will be based on the lessons learnt during this period"--Publisher's description.
Book Synopsis One Health and the Politics of Antimicrobial Resistance by : Laura H. Kahn
Download or read book One Health and the Politics of Antimicrobial Resistance written by Laura H. Kahn and published by JHU Press. This book was released on 2016-08-15 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the use of low-dose antibiotics in livestock put human health at risk? Zoonoses—infectious diseases, such as SARS and mad cow, that originate in animals and spread to humans—reveal how intimately animal and human health are linked. Complicating this relationship further, when livestock are given antibiotics to increase growth, it can lead to resistant bacteria. Unfortunately, there are few formal channels for practitioners of human medicine and veterinary medicine to communicate about threats to public health. To address this problem, Dr. Laura H. Kahn and her colleagues are promoting the One Health concept, which seeks to increase communication and collaboration between professionals in human, animal, and environmental health. In One Health and the Politics of Antimicrobial Resistance, Dr. Kahn investigates the use of antibiotics and the surge in antimicrobial resistance in food animals and humans from a One Health perspective. Although the medical community has blamed the problem on agricultural practices, the agricultural community insists that antibiotic resistance is the result of indiscriminate use of antibiotics in human medicine. Dr. Kahn argues that this blame game has fueled the politics of antibiotic resistance and hindered the development of effective policies to address the worsening crisis. Combining painstaking research with unprecedented access to international data, the book analyzes the surprising outcomes of differing policy approaches to antibiotic resistance around the globe. By integrating the perspectives of both medicine and agriculture and exploring the history and science behind the widespread use of growth-promoting antibiotics, One Health and the Politics of Antimicrobial Resistance examines the controversy in a unique way while offering policy recommendations that all sides can accept.
Book Synopsis Risk-Taking in International Politics by : Rose McDermott
Download or read book Risk-Taking in International Politics written by Rose McDermott and published by University of Michigan Press. This book was released on 2001 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses the way leaders deal with risk in making foreign policy decisions
Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Book Synopsis Antimicrobial Resistance by : World Health Organization
Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
Book Synopsis UCL Hospitals Injectable Medicines Administration Guide by : University College London Hospitals
Download or read book UCL Hospitals Injectable Medicines Administration Guide written by University College London Hospitals and published by John Wiley & Sons. This book was released on 2013-07-19 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: "I would definitely recommend this book to all staff with an interest and involvement in intravenous drug therapy." —The Pharmaceutical Journal "There is no doubt that nurses will find this small book useful. It should be available for consultation in any clinical area where drugs are administered to patients by the injectable routes." —Journal of Clinical Nursing The safe administration of injectable medicines is key to patient safety. The NPSA recognises the use of injectable medicines is a high risk activity and recommends written information about injectables to be available at the point of preparation. The UCL Hospitals Injectable Medicines Administration Guide is a practical, accessible guide covering many important aspects of administering medicines by injection. It provides clear, concise information on the preparation and administration of over 245 injectable medicines for adults, paediatrics and neonates. It is an essential resource for nurses and other healthcare professionals: it provides the key information and advice needed for the safe and effective administration of injectable medicines. The Guide’s introductory section provides a concise yet comprehensive overview of injectable therapy, including the risks and benefits of IV administration, infusion devices, and pharmaceutical aspects of injectable therapy. For each drug the alphabetically tabulated monographs provide: A practical method of preparation and administration via the IV, IM and SC routes, with risk reduction in mind at every step Expert advice from the team of specialist pharmacists at UCLH to ensure safe and pragmatic use of each medicine Monitoring advice for the management of reactions that may occur during administration Y-site and syringe driver compatibility data Minimum infusion volume data for fluid restricted patients Extravasation warnings, pH, sodium content, displacement values, stability and flush data New to this edition: 40 new monographs including recently marketed, unlicensed, rarely used and specialist medicines Detailed advice for the administration of high risk medicines such as heparin, with access to UCLH’s medicine related guidelines at www.wiley.com/go/UCLH A colour-coded NPSA risk assessment for every mode of administration for every medicine, to highlight the safest method of administration A user guide and tutorial to give new readers confidence in using and understanding the Guide Revised chapters on administration methods and devices, aseptic non-touch technique, and latex allergy Fully revised and expanded Y-site compatibility section Spiral binding to allow the book to be left open at the relevant page The Guide is also available electronically at www.uclhguide.com.
Download or read book Risk and Decision Making written by and published by National Academies Press. This book was released on 1982-01-01 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
