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Author : Lawrence Archer
Publisher : Pluto Press (UK)
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.3/5 (555 download)
Download or read book Ricin! written by Lawrence Archer and published by Pluto Press (UK). This book was released on 2010-10-15 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the ways in which parliamentary committees can enhance democratic governance.
Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Nilgun E. Tumer
Publisher : MDPI
ISBN 13 : 3039285122
Total Pages : 154 pages
Book Rating : 4.0/5 (392 download)
Download or read book Ricin Toxins written by Nilgun E. Tumer and published by MDPI. This book was released on 2020-12-14 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plant toxin ricin is one of the most potent and lethal substances known. Due to its wide availability and the ease of production, ricin has been exploited as an agent of bioterrorism and biological warfare and is classified as a level B threat. Tons of ricin are produced annually worldwide as a by-product of castor oil, leading to exposure. Currently, there is no proven safe treatment for ricin intoxication. Ricin consists of an active A subunit (RTA) covalently linked to a cell binding B subunit (RTB). RTA depurinates a universally conserved adenine in the sarcin–ricin loop (SRL) of the large rRNA and inhibits protein synthesis. RTA-antibody complexes have been explored as immunotoxins against cancer cells. The articles published in this book address the history of ricin research, how ricin enters cells and traffics to the ribosome, how it inactivates ribosomes, how it induces inflammatory signaling pathways and programmed cell death, the design of therapies against ricin intoxication, and innovative assays for ricin detection.
Author : P. Gopalakrishnakone
Publisher : Springer
ISBN 13 : 9789400758681
Total Pages : 0 pages
Book Rating : 4.7/5 (586 download)
Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Author :
Publisher : DIANE Publishing
ISBN 13 : 9781422328590
Total Pages : 12 pages
Book Rating : 4.3/5 (285 download)
Download or read book Methods to Characterize Ricin for the Development of Reference Materials written by and published by DIANE Publishing. This book was released on with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nicholas Mantis
Publisher : Springer Science & Business Media
ISBN 13 : 3642274692
Total Pages : 283 pages
Book Rating : 4.6/5 (422 download)
Download or read book Ricin and Shiga Toxins written by Nicholas Mantis and published by Springer Science & Business Media. This book was released on 2012-01-16 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: In May of 2011, Western Europe experienced a severe outbreak of Shiga toxin (Stx)-producing E. coli (STEC) that culminated in more than 3200 cases and 39 deaths. While Stx is not the only virulence factor associated with STEC, it is certainly the primary determinant associated with the onset of hemolytic uremic syndrome (HUS). At the present time, there are no clinically approved measures to neutralize Stx in individuals suffering from STEC infection. Nor are there any preventatives or therapeutics for ricin toxin. Although incidents of ricin exposure are largely unheard of, federal agencies and public health officials consider it a significant threat. It is well documented that domestic and international terrorist groups have stockpiled, and in some cases weaponized ricin with the intent of releasing it into the public sphere and causing panic, illness and/or death on a local, regional, or possibly national scale. The chapters, written by leading experts in the field, are organized so as to cover all aspects of ricin and Stx, including pathogenesis, immunity, vaccines and therapeutics. This outstanding collection of reviews will serve as an important and readily accessible resource for the research community in the coming years.
Author : Arthur E. Frankel
Publisher : Springer Science & Business Media
ISBN 13 : 9780898389845
Total Pages : 606 pages
Book Rating : 4.3/5 (898 download)
Download or read book Immunotoxins written by Arthur E. Frankel and published by Springer Science & Business Media. This book was released on 1988-05-31 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Author : Neil Bradbury, Ph.D.
Publisher : St. Martin's Press
ISBN 13 : 1250270766
Total Pages : 234 pages
Book Rating : 4.2/5 (52 download)
Download or read book A Taste for Poison written by Neil Bradbury, Ph.D. and published by St. Martin's Press. This book was released on 2022-02-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A fascinating tale of poisons and poisonous deeds which both educates and entertains.” --Kathy Reichs A brilliant blend of science and crime, A TASTE FOR POISON reveals how eleven notorious poisons affect the body--through the murders in which they were used. As any reader of murder mysteries can tell you, poison is one of the most enduring—and popular—weapons of choice for a scheming murderer. It can be slipped into a drink, smeared onto the tip of an arrow or the handle of a door, even filtered through the air we breathe. But how exactly do these poisons work to break our bodies down, and what can we learn from the damage they inflict? In a fascinating blend of popular science, medical history, and true crime, Dr. Neil Bradbury explores this most morbidly captivating method of murder from a cellular level. Alongside real-life accounts of murderers and their crimes—some notorious, some forgotten, some still unsolved—are the equally compelling stories of the poisons involved: eleven molecules of death that work their way through the human body and, paradoxically, illuminate the way in which our bodies function. Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin & tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom, A Taste for Poison leads readers on a riveting tour of the intricate, complex systems that keep us alive—or don’t.
Author :
Publisher : Simon and Schuster
ISBN 13 : 1668008718
Total Pages : 464 pages
Book Rating : 4.6/5 (68 download)
Download or read book written by and published by Simon and Schuster. This book was released on with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tony Hargreaves
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162988
Total Pages : 199 pages
Book Rating : 4.8/5 (391 download)
Download or read book Poisons and Poisonings written by Tony Hargreaves and published by Royal Society of Chemistry. This book was released on 2020-08-28 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is London in the 1890s. A young woman has just taken a dose of a tonic she’s been given in the belief that it will improve her complexion. About ten minutes pass and she starts to experience breathing difficulties. Another minute and she collapses. Mercifully, death arrives but the poison has not yet finished, for the process of rigor mortis has set in with unusual speed. Her body is frozen into a rigid and contorted mass. This is the horror of strychnine, the nastiest of poisons. Despite knowing all the dreadfulness of this poison, Dr Thomas Neill Cream, the Lambeth Poisoner, used it to kill several prostitutes. And who knows how many other victims experienced the horror of strychnine, for it was by no means an uncommon poison. Today, there may well be more poisons available to the individual than ever before, but there are also advances in medical examination and forensic analysis that increase the likelihood of the poisoner being caught. This book will examine poisons, both natural and man-made menaces, and cases based on a particular poison as well as information about how forensic analysis is conducted. Appealing to scientists and non-scientists alike, this enthralling book will entertain and educate and bring the reader up to date with how important chemical analysis is in crime detection.
Author : Peter Macinnis
Publisher : Allen & Unwin
ISBN 13 : 1741154375
Total Pages : 257 pages
Book Rating : 4.7/5 (411 download)
Download or read book The Killer Bean of Calabar and Other Stories written by Peter Macinnis and published by Allen & Unwin. This book was released on 2004-07-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: A triumphantly toxic tome. As a dedicated Macinnis fan, I relish this latest display of erudition, story-telling and fun. One of his very best.' Robyn Williams, Head, ABC Science Unit Was Abraham Lincoln really as mad as a hatter? Who poisoned Phar Lap? Can wallpaper really kill? Was Jack the Ripper an arsenic eater? Painting a broad canvas, from the early Egyptians to the arsenical tube wells in Bangladesh and the Sarin gas attacks in a Tokyo subway, The Killer Bean of Calabar explores the accidental and intentional tales of poisons and their use throughout history. Historically difficult substances to trace, poisons have been used by many for their own dastardly purposes, from the Great Poisoners such as Nero and Madame de Brinvilliers to the mass gassings of World War II. But the truly great poisoners are those who make selective use of poisons to save human life, not the few who use poison to take human life. Most of the medicines we take are themselves poisons - therapeutic only by virtue of being more deadly to our viruses than to us. Poisons are all around us - from the plants in our gardens and lead in our homes, to the bacteria and toxins in our bodies. With ripping yarns and unusual views of famous people, Macinnis explains the whys and wherefores of poisons and poisoning.
Author : Alan Woolf
Publisher : Academic Press
ISBN 13 : 0128222190
Total Pages : 648 pages
Book Rating : 4.1/5 (282 download)
Download or read book History of Modern Clinical Toxicology written by Alan Woolf and published by Academic Press. This book was released on 2021-10-13 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are. - Offers descriptions of the key regulatory advances affecting clinical toxicology - Provides synopses of modern-day poisoning disasters - Outlines the development of modern antidotes and future directions in clinical toxicology - Describes the origins and development of the U.S. poison control system - Includes the origins and features of professional clinical toxicology societies from around the world - Includes descriptions of the history of clinical toxicology and poison control in more than 35 countries
Author : William Powell
Publisher : Lulu.com
ISBN 13 : 1387570226
Total Pages : 164 pages
Book Rating : 4.3/5 (875 download)
Download or read book The Anarchist Cookbook written by William Powell and published by Lulu.com. This book was released on 2018-02-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Anarchist Cookbook will shock, it will disturb, it will provoke. It places in historical perspective an era when "Turn on, Burn down, Blow up" are revolutionary slogans of the day. Says the author" "This book... is not written for the members of fringe political groups, such as the Weatherman, or The Minutemen. Those radical groups don't need this book. They already know everything that's in here. If the real people of America, the silent majority, are going to survive, they must educate themselves. That is the purpose of this book." In what the author considers a survival guide, there is explicit information on the uses and effects of drugs, ranging from pot to heroin to peanuts. There i detailed advice concerning electronics, sabotage, and surveillance, with data on everything from bugs to scramblers. There is a comprehensive chapter on natural, non-lethal, and lethal weapons, running the gamut from cattle prods to sub-machine guns to bows and arrows.
Author : Brian J. Lukey
Publisher : CRC Press
ISBN 13 : 1420046624
Total Pages : 752 pages
Book Rating : 4.4/5 (2 download)
Download or read book Chemical Warfare Agents written by Brian J. Lukey and published by CRC Press. This book was released on 2007-12-17 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.
Author : Ernest Hodgson
Publisher : Academic Press
ISBN 13 : 0124158137
Total Pages : 452 pages
Book Rating : 4.1/5 (241 download)
Download or read book Toxicology and Human Environments written by Ernest Hodgson and published by Academic Press. This book was released on 2012-09-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments. The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis. Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them
Author : Arthur Frankel
Publisher : CRC Press
ISBN 13 : 9780824784546
Total Pages : 516 pages
Book Rating : 4.7/5 (845 download)
Download or read book Genetically Engineered Toxins written by Arthur Frankel and published by CRC Press. This book was released on 1992-06-19 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting all preclinical and clinical information available on genetically engineered toxins, this unique, single-source reference provides the most up-to-date methods and practical examples for conducting clinical studies in toxin molecular biology.;Reviewing difficult problems and their solutions, Genetically Engineered Toxins discusses techniques for clo;ning, expressing, and purifying recombinant toxins and genetically modified recombinant toxins; documents structure-function relationships in toxins, including comparative information; supplies theory and illustrations of chimeric toxins; delineates the preclinical assessments of new reagents; and summarizes approaches to drug design.;With over 1100 literature citations, Genetically Engineered Toxins is an invaluable resource for biochemists, molecular biologists, biotechnologists, pharmacologists, toxicologists, X-ray crystallographers, enzymologists, oncologists, hematologists, immunologists, rheumatologists, botanists, and graduate-level students in molecular biology, biotechnology, and clinical oncology courses.
Author : John Emsley
Publisher : Royal Society of Chemistry
ISBN 13 : 1782627995
Total Pages : 255 pages
Book Rating : 4.7/5 (826 download)
Download or read book Molecules of Murder written by John Emsley and published by Royal Society of Chemistry. This book was released on 2015-12-07 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecules of Murder is about infamous murderers and famous victims; about people like Harold Shipman, Alexander Litvinenko, Adelaide Bartlett, and Georgi Markov. Few books on poisons analyse these crimes from the viewpoint of the poison itself, doing so throws a new light on how the murders or attempted murders were carried out and ultimately how the perpetrators were uncovered and brought to justice. Part I includes molecules which occur naturally and were originally used by doctors before becoming notorious as murder weapons. Part II deals with unnatural molecules, mainly man-made, and they too have been dangerously misused in famous crimes. The book ends with the most famous poisoning case in recent years, that of Alexander Litvinenko and his death from polonium chloride. The first half of each chapter starts by looking at the target molecule itself, its discovery, its history, its chemistry, its use in medicine, its toxicology, and its effects on the human body. The second half then investigates a famous murder case and reveals the modus operandi of the poisoner and how some were caught, some are still at large, and some literally got away with murder. Molecules of Murder will explain how forensic chemists have developed cunning ways to detect minute traces of dangerous substances, and explain why some of these poisons, which appear so life-threatening, are now being researched as possible life-savers. Award winning science writer John Emsley has assembled another group of true crime and chemistry stories to rival those of his highly acclaimed Elements of Murder.
