A Review of Human Carcinogens

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (815 download)

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Book Synopsis A Review of Human Carcinogens by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference

Download or read book A Review of Human Carcinogens written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carcinogens and Anticarcinogens in the Human Diet

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Publisher : National Academies Press
ISBN 13 : 0309175712
Total Pages : 433 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Carcinogens and Anticarcinogens in the Human Diet by : National Research Council

Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-02-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide

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Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

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Publisher : IARC Monographs on the Evaluat
ISBN 13 : 9789283213246
Total Pages : 0 pages
Book Rating : 4.2/5 (132 download)

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Book Synopsis Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

A Review of Human Carcinogens: Radiation

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis A Review of Human Carcinogens: Radiation by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting

Download or read book A Review of Human Carcinogens: Radiation written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Outdoor Air Pollution

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Publisher : IARC Monographs on the Evaluat
ISBN 13 : 9789283201472
Total Pages : 0 pages
Book Rating : 4.2/5 (14 download)

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Book Synopsis Outdoor Air Pollution by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Outdoor Air Pollution written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."

Smokeless Tobacco and Some Tobacco-specific N-nitrosamines

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Publisher : World Health Organization
ISBN 13 : 9283212894
Total Pages : 642 pages
Book Rating : 4.2/5 (832 download)

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Book Synopsis Smokeless Tobacco and Some Tobacco-specific N-nitrosamines by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Smokeless Tobacco and Some Tobacco-specific N-nitrosamines written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2007 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary smoking (second-hand smoke or environmental tobacco smoke) (IARC 2004a). Volume 85 summarized the evidence on the carcinogenic risk of chewing betel quid with and without tobacco (IARC 2004b). That volume explored the variety of products chewed in South Asia and other parts of the word that contain areca nut in combination with other ingredients, often including tobacco. In this eighty-ninth volume, the carcinogenic risks associated with the use of smokeless tobacco, including chewing tobacco and snuff, are considered in a first monograph. The second monograph reviews some tobacco-specific nitrosamines. These agents were evaluated earlier in Volume 37 of the Monographs (IARC 1985) and information gathered since that time has been summarized and evaluated.

A Review of Human Carcinogens

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Publisher : IARC Monographs on the Evaluat
ISBN 13 :
Total Pages : 604 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis A Review of Human Carcinogens by : International Agency for Research on Cancer

Download or read book A Review of Human Carcinogens written by International Agency for Research on Cancer and published by IARC Monographs on the Evaluat. This book was released on 2012 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 100 compiles information on tumor sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Much can be learned by updating the assessments of agents that are known to cause cancer in humans. Accordingly, IARC has selected A Review of Human Carcinogensto be the topic for Volume 100. It is hoped that this volume, by compiling the knowledge accumulated through several decades of cancer research, will stimulate cancer prevention activities worldwide, and will be a valued resource for future research to identify other agents suspected of causing cancer in humans. Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations. Because the scope of Volume 100 is so broad, its Monographs are focused on key information. Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the agent's toxicokinetics, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results are printed in Volume 100, and more extensive tables that include all studies appear on the Monographs programe website (http://monographs.iarc.fr/). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given.

The Carcinogenicity of Metals

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849737193
Total Pages : 449 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis The Carcinogenicity of Metals by : Alan B. G. Lansdown

Download or read book The Carcinogenicity of Metals written by Alan B. G. Lansdown and published by Royal Society of Chemistry. This book was released on 2013-10-31 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book re-evaluates epidemiological and occupational health studies, experimental studies in animals and in vitro experiments relating to the toxicity of 27 metal and metalloid elements for which evidence of carcinogenicity has been presented. Human carcinogenic risk is substantiated in relation to arsenic, beryllium, thorium, chromium, radioactive elements, probably lead, and some nickel and cobalt compounds, and respirable silica particles, but the carcinogenicity of iron, aluminium, titanium, tungsten, antimony, bismuth, mercury, precious metals, and certain related compounds in humans is unresolved. The toxicity and carcinogenicity of each element is specific but correlates poorly with its position in the Periodic Table. Carcinogenicity differs according to the valency of the ion and its ability to interact with and penetrate membranes in target cells and to bind, denature or induce mutations by genotoxic or epigenetic mechanisms. This important text comprehensively examines each of the elements providing detailed information on the carcinogenicity and toxicity and detailing the most up-to-date research in this area. The book is an essential tool for toxicologists, medicinal and biochemists, and environmental scientists working in both industry and academia.

Chemical Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1617379956
Total Pages : 447 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis Chemical Carcinogenesis by : Trevor M. Penning

Download or read book Chemical Carcinogenesis written by Trevor M. Penning and published by Springer Science & Business Media. This book was released on 2011-03-03 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

A Review of Human Carcinogens: Biological agents

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis A Review of Human Carcinogens: Biological agents by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting

Download or read book A Review of Human Carcinogens: Biological agents written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Some Organophosphate Insecticides and Herbicides

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Publisher : World Health Organization
ISBN 13 : 9789283201502
Total Pages : 0 pages
Book Rating : 4.2/5 (15 download)

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Book Synopsis Some Organophosphate Insecticides and Herbicides by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Organophosphate Insecticides and Herbicides written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.

A Review of Human Carcinogens. F. Chemical Agents and Related Occupations

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Publisher : International Agency for Research on Cancer
ISBN 13 :
Total Pages : 636 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis A Review of Human Carcinogens. F. Chemical Agents and Related Occupations by : International Agency for Research on Cancer

Download or read book A Review of Human Carcinogens. F. Chemical Agents and Related Occupations written by International Agency for Research on Cancer and published by International Agency for Research on Cancer. This book was released on 2012-09-24 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 100 compiles information on tumor sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Much can be learned by updating the assessments of agents that are known to cause cancer in humans. Accordingly, IARC has selected A Review of Human Carcinogensto be the topic for Volume 100. It is hoped that this volume, by compiling the knowledge accumulated through several decades of cancer research, will stimulate cancer prevention activities worldwide, and will be a valued resource for future research to identify other agents suspected of causing cancer in humans. Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations. Because the scope of Volume 100 is so broad, its Monographs are focused on key information. Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the agent's toxicokinetics, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results are printed in Volume 100, and more extensive tables that include all studies appear on the Monographs programe website (http://monographs.iarc.fr/). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given.

Some Nanomaterials and Some Fibres

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Publisher : IARC Monographs on the Evaluat
ISBN 13 : 9789283201496
Total Pages : 0 pages
Book Rating : 4.2/5 (14 download)

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Book Synopsis Some Nanomaterials and Some Fibres by : International Agency for Research on Cancer

Download or read book Some Nanomaterials and Some Fibres written by International Agency for Research on Cancer and published by IARC Monographs on the Evaluat. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of fluoro-edenite fibrous amphibole, silicon carbide fibres and whiskers, and carbon nanotubes, including single-walled and multiwalled types. None of these agents had been assessed previously by the IARC Monographs Working Group. The Working Group relied mainly on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to fluoro-edenite fibrous amphibole, an environmental contaminant that was reported to cause mesothelioma in the regional population of Biancavilla, Sicily, Italy. Silicon carbide fibres are by-products of the manufacture of silicon carbide particles by the Acheson process; silicon carbide whiskers are produced by other processes. The evaluations of the fibres and of the occupational exposures associated with the Acheson process were mainly based on epidemiological studies, whereas the assessment of the whiskers--in the absence of epidemiological--was based on carcinogenicity bioassays and consideration of their physical properties. In view of the absence of epidemiological studies on carbon nanotubes and the limited information available from mechanistic data, the evaluations of single-walled and multiwalled carbon nanotubes relied essentially on carcinogenicity bioassays.

The American Cancer Society's Principles of Oncology

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Publisher : John Wiley & Sons
ISBN 13 : 1119468841
Total Pages : 472 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The American Cancer Society's Principles of Oncology by : The American Cancer Society

Download or read book The American Cancer Society's Principles of Oncology written by The American Cancer Society and published by John Wiley & Sons. This book was released on 2018-03-20 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners is a comprehensive reference covering the diagnosis of cancer, and a range of related issues that are key to a multidisciplinary approach to cancer and critical to cancer control and may be used in conjunction with the book, The American Cancer Society's Oncology in Practice: Clinical Management. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a deeper understanding of cancer prevention, screening, and follow-up, which are central to the ACS's worldwide mission on cancer control.

A Review of Human Carcinogens: Pharmaceuticals

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis A Review of Human Carcinogens: Pharmaceuticals by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting

Download or read book A Review of Human Carcinogens: Pharmaceuticals written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: