Restricted Data

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Author :
Publisher : University of Chicago Press
ISBN 13 : 0226833445
Total Pages : 558 pages
Book Rating : 4.2/5 (268 download)

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Book Synopsis Restricted Data by : Alex Wellerstein

Download or read book Restricted Data written by Alex Wellerstein and published by University of Chicago Press. This book was released on 2024-04-23 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first full history of US nuclear secrecy, from its origins in the late 1930s to our post–Cold War present. The American atomic bomb was born in secrecy. From the moment scientists first conceived of its possibility to the bombings of Hiroshima and Nagasaki and beyond, there were efforts to control the spread of nuclear information and the newly discovered scientific facts that made such powerful weapons possible. The totalizing scientific secrecy that the atomic bomb appeared to demand was new, unusual, and very nearly unprecedented. It was foreign to American science and American democracy—and potentially incompatible with both. From the beginning, this secrecy was controversial, and it was always contested. The atomic bomb was not merely the application of science to war, but the result of decades of investment in scientific education, infrastructure, and global collaboration. If secrecy became the norm, how would science survive? Drawing on troves of declassified files, including records released by the government for the first time through the author’s efforts, Restricted Data traces the complex evolution of the US nuclear secrecy regime from the first whisper of the atomic bomb through the mounting tensions of the Cold War and into the early twenty-first century. A compelling history of powerful ideas at war, it tells a story that feels distinctly American: rich, sprawling, and built on the conflict between high-minded idealism and ugly, fearful power.

Occupational Outlook Handbook

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Author :
Publisher :
ISBN 13 :
Total Pages : 740 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Occupational Outlook Handbook by : United States. Bureau of Labor Statistics

Download or read book Occupational Outlook Handbook written by United States. Bureau of Labor Statistics and published by . This book was released on 1957 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Restricted Data

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022602041X
Total Pages : 558 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Restricted Data by : Alex Wellerstein

Download or read book Restricted Data written by Alex Wellerstein and published by University of Chicago Press. This book was released on 2021-04-09 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first full history of US nuclear secrecy, from its origins in the late 1930s to our post–Cold War present. The American atomic bomb was born in secrecy. From the moment scientists first conceived of its possibility to the bombings of Hiroshima and Nagasaki and beyond, there were efforts to control the spread of nuclear information and the newly discovered scientific facts that made such powerful weapons possible. The totalizing scientific secrecy that the atomic bomb appeared to demand was new, unusual, and very nearly unprecedented. It was foreign to American science and American democracy—and potentially incompatible with both. From the beginning, this secrecy was controversial, and it was always contested. The atomic bomb was not merely the application of science to war, but the result of decades of investment in scientific education, infrastructure, and global collaboration. If secrecy became the norm, how would science survive? Drawing on troves of declassified files, including records released by the government for the first time through the author’s efforts, Restricted Data traces the complex evolution of the US nuclear secrecy regime from the first whisper of the atomic bomb through the mounting tensions of the Cold War and into the early twenty-first century. A compelling history of powerful ideas at war, it tells a story that feels distinctly American: rich, sprawling, and built on the conflict between high-minded idealism and ugly, fearful power.

Sharing Clinical Trial Data

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Author :
Publisher : National Academies Press
ISBN 13 : 0309316324
Total Pages : 304 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Sharing Clinical Trial Data by : Institute of Medicine

Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research--from funders, to researchers, to journals, to physicians, and ultimately, to patients.

Guidelines Manual

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Publisher :
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Guidelines Manual by : United States Sentencing Commission

Download or read book Guidelines Manual written by United States Sentencing Commission and published by . This book was released on 1988-10 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pensions in the Health and Retirement Study

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Publisher : Harvard University Press
ISBN 13 : 9780674048669
Total Pages : 404 pages
Book Rating : 4.0/5 (486 download)

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Book Synopsis Pensions in the Health and Retirement Study by : Alan L. Gustman

Download or read book Pensions in the Health and Retirement Study written by Alan L. Gustman and published by Harvard University Press. This book was released on 2010-05 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a careful analysis of pension data collected by the Health and Retirement Study, a unique survey of people over the age of fifty conducted by the University of Michigan for the National Institute on Aging. The authors studied pensions as they evolve over individuals’ work lives and into retirement: how pension coverage and plans change over a lifetime, how many pensions workers have by the time they retire and what these pensions are worth, what pensions contribute to individual retirement incomes, and how trends and policy changes affect retirement plans. The book focuses on the major features of pensions, including plan type and participation, ages of eligibility for retirement, values of different pension types, how pension values are influenced by retirement age, how plans are settled when a worker leaves a firm, how well people understand their pensions, the importance of pensions in retirement saving and as a share of household wealth, and the vulnerability of the retirement age population to the current financial crisis. This book provides readers with an invaluable look at the crucial but ever-changing role of pensions in supporting retirees.

Innovations in Federal Statistics

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Author :
Publisher : National Academies Press
ISBN 13 : 030945428X
Total Pages : 151 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Innovations in Federal Statistics by : National Academies of Sciences, Engineering, and Medicine

Download or read book Innovations in Federal Statistics written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-21 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Federal government statistics provide critical information to the country and serve a key role in a democracy. For decades, sample surveys with instruments carefully designed for particular data needs have been one of the primary methods for collecting data for federal statistics. However, the costs of conducting such surveys have been increasing while response rates have been declining, and many surveys are not able to fulfill growing demands for more timely information and for more detailed information at state and local levels. Innovations in Federal Statistics examines the opportunities and risks of using government administrative and private sector data sources to foster a paradigm shift in federal statistical programs that would combine diverse data sources in a secure manner to enhance federal statistics. This first publication of a two-part series discusses the challenges faced by the federal statistical system and the foundational elements needed for a new paradigm.

The Freedom to Read

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Author :
Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis The Freedom to Read by : American Library Association

Download or read book The Freedom to Read written by American Library Association and published by . This book was released on 1953 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Econometric Analysis of Cross Section and Panel Data, second edition

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Author :
Publisher : MIT Press
ISBN 13 : 0262232588
Total Pages : 1095 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis Econometric Analysis of Cross Section and Panel Data, second edition by : Jeffrey M. Wooldridge

Download or read book Econometric Analysis of Cross Section and Panel Data, second edition written by Jeffrey M. Wooldridge and published by MIT Press. This book was released on 2010-10-01 with total page 1095 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a comprehensive state-of-the-art graduate level text on microeconometric methods, substantially revised and updated. The second edition of this acclaimed graduate text provides a unified treatment of two methods used in contemporary econometric research, cross section and data panel methods. By focusing on assumptions that can be given behavioral content, the book maintains an appropriate level of rigor while emphasizing intuitive thinking. The analysis covers both linear and nonlinear models, including models with dynamics and/or individual heterogeneity. In addition to general estimation frameworks (particular methods of moments and maximum likelihood), specific linear and nonlinear methods are covered in detail, including probit and logit models and their multivariate, Tobit models, models for count data, censored and missing data schemes, causal (or treatment) effects, and duration analysis. Econometric Analysis of Cross Section and Panel Data was the first graduate econometrics text to focus on microeconomic data structures, allowing assumptions to be separated into population and sampling assumptions. This second edition has been substantially updated and revised. Improvements include a broader class of models for missing data problems; more detailed treatment of cluster problems, an important topic for empirical researchers; expanded discussion of "generalized instrumental variables" (GIV) estimation; new coverage (based on the author's own recent research) of inverse probability weighting; a more complete framework for estimating treatment effects with panel data, and a firmly established link between econometric approaches to nonlinear panel data and the "generalized estimating equation" literature popular in statistics and other fields. New attention is given to explaining when particular econometric methods can be applied; the goal is not only to tell readers what does work, but why certain "obvious" procedures do not. The numerous included exercises, both theoretical and computer-based, allow the reader to extend methods covered in the text and discover new insights.

The Prevention and Treatment of Missing Data in Clinical Trials

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Author :
Publisher : National Academies Press
ISBN 13 : 030918651X
Total Pages : 163 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council

Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide

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Author :
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by . This book was released on 1999 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atomic Energy Programs

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Publisher :
ISBN 13 :
Total Pages : 108 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Atomic Energy Programs by : U.S. Atomic Energy Commission

Download or read book Atomic Energy Programs written by U.S. Atomic Energy Commission and published by . This book was released on 1973 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Model Rules of Professional Conduct

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Publisher : American Bar Association
ISBN 13 : 9781590318737
Total Pages : 216 pages
Book Rating : 4.3/5 (187 download)

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Book Synopsis Model Rules of Professional Conduct by : American Bar Association. House of Delegates

Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Gambling with Armageddon

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Author :
Publisher : Vintage
ISBN 13 : 0525659315
Total Pages : 624 pages
Book Rating : 4.5/5 (256 download)

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Book Synopsis Gambling with Armageddon by : Martin J. Sherwin

Download or read book Gambling with Armageddon written by Martin J. Sherwin and published by Vintage. This book was released on 2020-10-13 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Pulitzer Prize-winning author of American Prometheus comes the first effort to set the Cuban Missile Crisis, with its potential for nuclear holocaust, in a wider historical narrative of the Cold War—how such a crisis arose, and why at the very last possible moment it didn't happen. In this groundbreaking look at the Cuban Missile Crisis, Martin Sherwin not only gives us a riveting sometimes hour-by-hour explanation of the crisis itself, but also explores the origins, scope, and consequences of the evolving place of nuclear weapons in the post-World War II world. Mining new sources and materials, and going far beyond the scope of earlier works on this critical face-off between the United States and the Soviet Union—triggered when Khrushchev began installing missiles in Cuba at Castro's behest—Sherwin shows how this volatile event was an integral part of the wider Cold War and was a consequence of nuclear arms. Gambling with Armageddon looks in particular at the original debate in the Truman Administration about using the Atomic Bomb; the way in which President Eisenhower relied on the threat of massive retaliation to project U.S. power in the early Cold War era; and how President Kennedy, though unprepared to deal with the Bay of Pigs debacle, came of age during the Cuban Missile Crisis. Here too is a clarifying picture of what was going on in Khrushchev's Soviet Union. Martin Sherwin has spent his career in the study of nuclear weapons and how they have shaped our world. Gambling with Armegeddon is an outstanding capstone to his work thus far.

The Apocalypse Factory: Plutonium and the Making of the Atomic Age

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 0393634981
Total Pages : 352 pages
Book Rating : 4.3/5 (936 download)

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Book Synopsis The Apocalypse Factory: Plutonium and the Making of the Atomic Age by : Steve Olson

Download or read book The Apocalypse Factory: Plutonium and the Making of the Atomic Age written by Steve Olson and published by W. W. Norton & Company. This book was released on 2020-07-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thrilling narrative of scientific triumph, decades of secrecy, and the unimaginable destruction wrought by the creation of the atomic bomb. It began with plutonium, the first element ever manufactured in quantity by humans. Fearing that the Germans would be the first to weaponize the atom, the United States marshaled brilliant minds and seemingly inexhaustible bodies to find a way to create a nuclear chain reaction of inconceivable explosive power. In a matter of months, the Hanford nuclear facility was built to produce and weaponize the enigmatic and deadly new material that would fuel atomic bombs. In the desert of eastern Washington State, far from prying eyes, scientists Glenn Seaborg, Enrico Fermi, and many thousands of others—the physicists, engineers, laborers, and support staff at the facility—manufactured plutonium for the bomb dropped on Nagasaki, and for the bombs in the current American nuclear arsenal, enabling the construction of weapons with the potential to end human civilization. With his characteristic blend of scientific clarity and storytelling, Steve Olson asks why Hanford has been largely overlooked in histories of the Manhattan Project and the Cold War. Olson, who grew up just twenty miles from Hanford’s B Reactor, recounts how a small Washington town played host to some of the most influential scientists and engineers in American history as they sought to create the substance at the core of the most destructive weapons ever created. The Apocalypse Factory offers a new generation this dramatic story of human achievement and, ultimately, of lethal hubris.

Cochrane Handbook for Systematic Reviews of Interventions

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Author :
Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

The Code of Federal Regulations of the United States of America

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Author :
Publisher :
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Code of Federal Regulations of the United States of America by :

Download or read book The Code of Federal Regulations of the United States of America written by and published by . This book was released on 1999 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Code of Federal Regulations is the codification of the general and permanent rules published in the Federal Register by the executive departments and agencies of the Federal Government.