Response And Adaptation To Hypoxia

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Response and Adaptation to Hypoxia

Author : Sukhamay Lahiri
Publisher : Springer
ISBN 13 : 1461475740
Total Pages : 251 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Response and Adaptation to Hypoxia by : Sukhamay Lahiri

Download or read book Response and Adaptation to Hypoxia written by Sukhamay Lahiri and published by Springer. This book was released on 2013-05-27 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The underlying theme of this book is the biology of oxygen. The 22 chapters cover aspects of molecular, cellular, and integrative physiological functions. A fundamental evolutionary feature of the oxygen-consuming organism is that it developed a oxygen-sensing mechanism as apart of feedback control at the levels of molecules, organelles, organs, and systems. Oxygen sensing is partic ularly expressed in certain specific cells and tissues like peripheral chemore ceptors, erythroprotein-producing cells, and vascular smooth muscle. Apart of the book is focused on the current issues of this basic question of chemosen sing. Mitrochondria as the major site for cellular oxygen consumption is a nat ural candidate for cellular oxygen sensitivity and adaptation. A section deals with this question. A perennial question concerns chronic environment al oxy gen and the organism's response and adaptation to it. This theme runs through several chapters. Because comparative physiology often provides insight into the mechanisms of environment al adaptation, a chapter on respiration of high altitude birds has been incorporated. Obviously this book gives only glimpses of the immense field of oxygen biology. The book grew out of two meetings where these subjects were discussed. These meetings were sponsored by the American Physiological Society and the Federation of American Societies for Experimental Biology. We are grateful to the FASEB Program Committee and APS publication committee for their sup port. We owe much to Ms. Anne Miller for her editorial assistance. S. L. Philadelphia N. S . C. Cleveland R. S. F.

Low-Oxygen Stress in Plants

Author : Joost T. van Dongen
Publisher : Springer Science & Business Media
ISBN 13 : 3709112540
Total Pages : 426 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Low-Oxygen Stress in Plants by : Joost T. van Dongen

Download or read book Low-Oxygen Stress in Plants written by Joost T. van Dongen and published by Springer Science & Business Media. This book was released on 2014-01-17 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, knowledge about the multitude of adaptive responses of plants to low oxygen stress has grown immensely. The oxygen sensor mechanism has been discovered, the knowledge about the interaction network of gene expression is expanding and metabolic adaptations have been described in detail. Furthermore, morphological changes were investigated and the regulative mechanisms triggered by plant hormones or reactive oxygen species have been revealed. This book provides a broad overview of all these aspects of low oxygen stress in plants. It integrates knowledge from different disciplines such as molecular biology, biochemistry, ecophysiology and agricultural / horticultural sciences to comprehensively describe how plants cope with low oxygen stress and discuss its ecological and agronomical consequences. This book is written for plant scientists, biochemists and scientists in agriculture and ecophysiology.

Hypoxia and Human Diseases

Author : Jing Zheng
Publisher : BoD – Books on Demand
ISBN 13 : 9535128957
Total Pages : 456 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Hypoxia and Human Diseases by : Jing Zheng

Download or read book Hypoxia and Human Diseases written by Jing Zheng and published by BoD – Books on Demand. This book was released on 2017-02-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Hypoxia

Author : Robert C. Roach
Publisher : Springer Science & Business Media
ISBN 13 : 9780306466960
Total Pages : 466 pages
Book Rating : 4.4/5 (669 download)

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Book Synopsis Hypoxia by : Robert C. Roach

Download or read book Hypoxia written by Robert C. Roach and published by Springer Science & Business Media. This book was released on 2002-01-31 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Mosaic Evolution of Subterranean Mammals

Author : Eviatar Nevo
Publisher : Oxford University Press, USA
ISBN 13 : 9780198575726
Total Pages : 0 pages
Book Rating : 4.5/5 (757 download)

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Book Synopsis Mosaic Evolution of Subterranean Mammals by : Eviatar Nevo

Download or read book Mosaic Evolution of Subterranean Mammals written by Eviatar Nevo and published by Oxford University Press, USA. This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Subterranean life exists within an extraordinary environment and has evolved among different groups of mammals all over the globe. With relatively constant temperature, few opportunities to meet organisms other than the immediate family, and a completely different sensory environment, the evolution of such life is fascinating. Locomotion, communication, food-finding, navigation, circadian rhythms, and indeed the whole of the animals' physiology may be specialized to cope with life underground. And from burrowing to blindness, magnetic communication to the weird bee-like eusociality of blind mole rats, specialization has been extreme and has led to speciation in a whole range of new contexts. That the subterranean way of life occurs in different species of mammals across the globe has provided scientists with one of nature's best studied global evolutionary demonstrations of adaptive radiation and speciation. The revolution in molecular biology that has occurred over the last ten years has massively expanded these horizons, allowing scientists to explore, map, and clone the genes underlying the basis of adaptation and speciation and translate their fascinating structural and functional evolution into genes and genomic language. This book draws together the burgeoning literature about all aspects of the biology of subterranean mammals. Beginning with their evolutionary history and the processes that led to the subterranean way of life, the author reviews ecology, behavior, and physiology within the context of the highly stressful subterranean context, considers the specialization that has evolved in response, and then compares the eleven families of extant subterranean mammals. The incredible circumstances surrounding subterranean mammals present a unique, global, 'natural experiment' in evolution that has implications throughout biology. As such, this broad survey will stand as an invaluable reference to evolutionary biologists, ecologists, and molecular biologists for years to come.

High Altitude

Author : Erik R. Swenson
Publisher : Springer Science & Business Media
ISBN 13 : 1461487722
Total Pages : 496 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis High Altitude by : Erik R. Swenson

Download or read book High Altitude written by Erik R. Swenson and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. High Altitude: Human Adaptation to Hypoxia is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases.

Life in Extreme Environments

Author : Ricardo Amils Pibernat
Publisher : Springer Science & Business Media
ISBN 13 : 1402062850
Total Pages : 450 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Life in Extreme Environments by : Ricardo Amils Pibernat

Download or read book Life in Extreme Environments written by Ricardo Amils Pibernat and published by Springer Science & Business Media. This book was released on 2007-07-21 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an intriguing look at how life can adapt to many different extreme environments. It addresses the limits for life development and examines different strategies used by organisms to adapt to different extreme environments.

Adaptation to Altitude-Hypoxia in Vertebrates

Author : P. Bouverot
Publisher : Springer Science & Business Media
ISBN 13 : 3642823165
Total Pages : 188 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Adaptation to Altitude-Hypoxia in Vertebrates by : P. Bouverot

Download or read book Adaptation to Altitude-Hypoxia in Vertebrates written by P. Bouverot and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adaptation to altitude hypoxia is characterized by a variety offunctional changes which collectively facilitate oxygen trans port from the ambient medium to the cells of the body. All of these changes can be seen at one time or another in the course of hypoxic exposure. Yet, as already stressed (Hannon and Vogel, 1977), an examination of the literature gives only a sketchy and often conflicting picture of the exact nature of these changes and how they interact as a function of exposure duration. This is partly because of the limited number of variables explored in a given study, but it is also attributable to differences in experimental design, differences among species in susceptibility to hypoxia, nonstandardized experimental conditions, lack of proper control of physical (e. g. , temperature) and physiological variables (e. g. , body mass), failure to take measurements at key periods of exposure, and gaps in knowledge about some fundamental mechanisms. Furthermore the available data on animals native to high altitude are meager and/or inconclusive. Extensive further work under well-controlled experimental conditions is required before a detailed picture can be made. Nevertheless, it has been a guiding principle in the prepara tion of this monograph rather to summarize the vastly dis persed material that constitutes the comparative physiology of adaptation to high altitude into a coherent picture, than to provide a comprehensive survey of the field.

Prediction of Maternal and Fetal Syndrome of Preeclampsia

Author : Nidhi Sharma
Publisher : BoD – Books on Demand
ISBN 13 : 1789847222
Total Pages : 156 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Prediction of Maternal and Fetal Syndrome of Preeclampsia by : Nidhi Sharma

Download or read book Prediction of Maternal and Fetal Syndrome of Preeclampsia written by Nidhi Sharma and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical syndrome of preeclampsia is due to vasospasm, endothelial dysfunction, and altered red cell zeta potential. It is a culmination of multiple etiologies and pathophysiologies modified by epigenetics and the human immune system. Since the etiology and pathogenesis of preeclampsia are segregated and multifactorial, there is no single clinical, biophysical, or biochemical marker that can predict all types of this condition. This book provides a set of tentative specific prediction markers that can be used to identify different subtypes of preeclampsia, classify pathogenesis, categorize treatment, and identify early signs of complications.

Plant Responses to Hypoxia

Author : Elena Loreti
Publisher : MDPI
ISBN 13 : 3036501487
Total Pages : 288 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Plant Responses to Hypoxia by : Elena Loreti

Download or read book Plant Responses to Hypoxia written by Elena Loreti and published by MDPI. This book was released on 2021-03-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular oxygen deficiency leads to altered cellular metabolism and can dramatically reduce crop productivity. Nearly all crops are negatively affected by a lack of oxygen (hypoxia) due to adverse environmental conditions such as excessive rain and soil waterlogging. Extensive efforts to fully understand how plants sense oxygen deficiency and their ability to respond using different strategies are crucial to increase hypoxia tolerance. Progress in our understanding has been significant in recent years. This topic certainly deserves more attention from the academic community; therefore, we have compiled a series of articles reflecting the advancements made thus far.

Respiratory Physiology of Vertebrates

Author : Göran E. Nilsson
Publisher : Cambridge University Press
ISBN 13 : 1139485350
Total Pages : 351 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Respiratory Physiology of Vertebrates by : Göran E. Nilsson

Download or read book Respiratory Physiology of Vertebrates written by Göran E. Nilsson and published by Cambridge University Press. This book was released on 2010-01-28 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do vertebrates get the oxygen they need, or even manage without it for shorter or longer periods of time? How do they sense oxygen, how do they take it up from water or air, and how do they transport it to their tissues? Respiratory system adaptations allow numerous vertebrates to thrive in extreme environments where oxygen availability is limited or where there is no oxygen at all. Written for students and researchers in comparative physiology, this authoritative summary of vertebrate respiratory physiology begins by exploring the fundamentals of oxygen sensing, uptake and transport in a textbook style. Subsequently, the reader is shown important examples of extreme respiratory performance, like diving and high altitude survival in mammals and birds, air breathing in fish, and those few vertebrates that can survive without any oxygen at all for several months, showing how evolution has solved the problem of life without oxygen.

Hypoxia

Author : Robert C. Roach
Publisher : Springer
ISBN 13 : 1489976787
Total Pages : 772 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Hypoxia by : Robert C. Roach

Download or read book Hypoxia written by Robert C. Roach and published by Springer. This book was released on 2016-06-24 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies. This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include: Epigenetic Variations in Hypoxia High Altitude Adaptation Hypoxia and Sleep Hypoxia and the Brain Molecular Oxygen Sensing Physiological Responses to Hypoxia

Hypoxia

Author : John R. Sutton
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hypoxia by : John R. Sutton

Download or read book Hypoxia written by John R. Sutton and published by . This book was released on 1990 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fish Physiology: Hypoxia

Author : Jeffrey G. Richards
Publisher : Academic Press
ISBN 13 : 9780080877990
Total Pages : 517 pages
Book Rating : 4.8/5 (779 download)

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Book Synopsis Fish Physiology: Hypoxia by : Jeffrey G. Richards

Download or read book Fish Physiology: Hypoxia written by Jeffrey G. Richards and published by Academic Press. This book was released on 2009-03-10 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periods of environmental hypoxia (Low Oxygen Availability) are extremely common in aquatic systems due to both natural causes such as diurnal oscillations in algal respiration, seasonal flooding, stratification, under ice cover in lakes, and isolation of densely vegetated water bodies, as well as more recent anthropogenic causes (e.g. eutrophication). In view of this, it is perhaps not surprising that among all vertebrates, fish boast the largest number of hypoxia tolerant species; hypoxia has clearly played an important role in shaping the evolution of many unique adaptive strategies. These unique adaptive strategies either allow fish to maintain function at low oxygen levels, thus extending hypoxia tolerance limits, or permit them to defend against the metabolic consequences of oxygen levels that fall below a threshold where metabolic functions cannot be maintained. The aim of this volume is two-fold. First, this book will review and synthesize the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure and place them within an environmental and ecological context. Second, through the development of a synthesis chapter this book will serve as the cornerstone for directing future research into the effects of hypoxia exposures on fish physiology and biochemistry. The only single volume available to provide an in-depth discussion of the adaptations and responses of fish to environmental hypoxia Reviews and synthesizes the adaptive behavioural, morphological, physiological, biochemical, and molecular strategies used by fish to survive hypoxia exposure Includes discussion of the evolutionary and ecological consequences of hypoxia exposure in fish

Physiological and Pathological Responses to Hypoxia and High Altitude

Author : Rodrigo Iturriaga
Publisher : Frontiers Media SA
ISBN 13 : 2889638006
Total Pages : 387 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Physiological and Pathological Responses to Hypoxia and High Altitude by : Rodrigo Iturriaga

Download or read book Physiological and Pathological Responses to Hypoxia and High Altitude written by Rodrigo Iturriaga and published by Frontiers Media SA. This book was released on 2020-06-22 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The appearance of photosynthetic organisms about 3 billion years ago increased the partial pressure of oxygen (PO2) in the atmosphere and enabled the evolution of organisms that use glucose and oxygen to produce ATP by oxidative phosphorylation. Hypoxia is commonly defined as the reduced availability of oxygen in the tissues produced by different causes, which include reduction of atmospheric PO2 as in high altitude, and secondary to pathological conditions such as sleep breathing and pulmonary disorders, anemia, and cardiovascular alterations leading to inadequate transport, delivery, and exchange of oxygen between capillaries and cells. Nowadays, it has been shown that hypoxia plays an important role in the genesis of several human pathologies including cardiovascular, renal, myocardial and cerebral diseases in fetal, young and adult life. Several mechanisms have evolved to maintain oxygen homeostasis. Certainly, all cells respond and adapt to hypoxia, but only a few of them can detect hypoxia and initiate a cascade of signals intended to produce a functional systemic response. In mammals, oxygen detection mechanisms have been extensively studied in erythropoietin-producing cells, chromaffin cells, bulbar and cortical neurons, pulmonary neuroepithelial cells, smooth muscle cells of pulmonary arteries, and chemoreceptor cells. While the precise mechanism underpinning oxygen, sensing is not completely known several molecular entities have been proposed as possible oxygen sensors (i.e. Hem proteins, ion channels, NADPH oxidase, mitochondrial cytochrome oxidase). Remarkably, cellular adaptation to hypoxia is mediated by the master oxygen-sensitive transcription factor, hypoxia-inducible factor-1, which can induce up-regulation of different genes to cope the cellular effects related to a decrease in oxygen levels. Short-term responses to hypoxia included mainly chemoreceptor-mediated reflex ventilatory and hemodynamic adaptations to manage the low oxygen concentration while more prolonged exposures to hypoxia can elicit more sustained physiological responses including switch from aerobic to anaerobic metabolism, vascularization, and enhancement of blood O2 carrying capacity. The focus of this research topic is to provide an up-to-date vision on the current knowledge on oxygen sensing mechanism, physiological responses to acute or chronic hypoxia and cellular/tissue/organ adaptations to hypoxic environment.

Surviving Hypoxia

Author : Peter W. Hochachka
Publisher : CRC Press
ISBN 13 : 1000714217
Total Pages : 587 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Surviving Hypoxia by : Peter W. Hochachka

Download or read book Surviving Hypoxia written by Peter W. Hochachka and published by CRC Press. This book was released on 2022-11-30 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms. Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.

Physiological Responses to Intermittent Hypoxia in Humans

Author : Jon C. Kolb
Publisher : Universal-Publishers
ISBN 13 : 1581122411
Total Pages : 196 pages
Book Rating : 4.5/5 (811 download)

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Book Synopsis Physiological Responses to Intermittent Hypoxia in Humans by : Jon C. Kolb

Download or read book Physiological Responses to Intermittent Hypoxia in Humans written by Jon C. Kolb and published by Universal-Publishers. This book was released on 2004 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, endurance athletes and high altitude climbers have gained access to commercially available, portable normobaric hypoxic chambers. Intermittent exposures to hypoxia in these chambers may elicit adaptations similar to those observed during acclimatization to altitude. Manufactures of these systems purport that intermittent exposures may elicit adaptations similar to those observed in response to the hypoxia of high altitude, however there have been no reports in the scientific literature that ventilatory acclimatization or alterations in cerebrovascular dynamics occur following repeated episodes in the portable chambers. The main conclusions are that an intermittent normobaric hypoxic intervention, consisting of five consecutive overnight exposures to a simulated altitude of 4300m, elicits perturbations in the acute cerebrovascular and ventilatory responses to both hypoxia and hypercapnia, which are similar to changes following chronic altitude exposure. Individual variability to intermittent hypoxia may have an impact on the rate at which the process of acclimatization proceeds. The extent of physiological and symptomatic responses to intermittent hypoxia are likely to be associated with the severity of hypoxia as well as the length and number of recurrent episodes of hypoxia.