Report of the Expert Meeting on Ciguatera Poisoning

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251325189
Total Pages : 156 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Report of the Expert Meeting on Ciguatera Poisoning by : Food and Agriculture Organization of the United Nations

Download or read book Report of the Expert Meeting on Ciguatera Poisoning written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2020-06-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytoplankton blooms, micro-algal blooms, toxic algae, red tides, or harmful algae, are all terms for naturally occurring phenomena that have occurred throughout recorded history. About 300 hundred species of micro algae are reported at times to form mass occurrence, so called blooms. Nearly one fourth of these species are known to produce toxins. Even non-toxic algal blooms can have devastating impacts when they lead to kills of fish and invertebrates by generating anoxic conditions. Some algal species, although non-toxic to humans, can produce exudates that can cause damage to the delicate gill tissues of fish (raphidophytes Chattonella, Heterosigma, and dinoflagellates Karenia, Karlodinium) . Aquatic animals can suffer devastating mortalities, which could lead economical and food losses, and eventually became a food security problem. Of greatest concern to humans are algal species that produce potent neurotoxins that can find their way through shellfish and fish to human consumers where they evoke a variety of gastrointestinal and neurological illnesses (paralytic shellfish poisoning (PSP), amnesic shellfish poisoning (ASP), diarrhoeic shellfish poisoning (DSP), neurotoxic shellfish poisoning (NSP), azaspiracid shellfish poisoning (AZP) and ciguatera fish poisoning (CFP)). Worldwide, ciguatoxins are estimated to cause around 50 000 cases of ciguatera fish poisoning annually; neurological effects may last for weeks or even years and one percent of these cases are fatal . Climate change and costal water over enrichment create an enabling environment for harmful algal blooms, which seem to have become more frequent, more intense and more widespread in the past decades.

Report of the expert meeting on food safety for seaweed – Current status and future perspectives

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251365903
Total Pages : 92 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Report of the expert meeting on food safety for seaweed – Current status and future perspectives by : ?Food and Agriculture Organization of the United Nations

Download or read book Report of the expert meeting on food safety for seaweed – Current status and future perspectives written by ?Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2022-09-30 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world production of marine macroalgae, or seaweed, has more than tripled since the turn of the millennium, increasing from 10.6 million tonnes in 2000 to 32.4 million tonnes in 2018. Increased cultivation and utilization of seaweed are expected to be important pillars of sustainable food security and a robust aquatic economy in the coming years. It is important, therefore, to consider the food safety implications of (increased) seaweed use for food. Many factors can affect the presence of hazards in seaweed, including: the type of seaweed, its physiology, the season in which it is produced, production waters, harvesting methods and processing. Several hazards such as heavy metals and marine biotoxins have been reported to be (potentially) associated with seaweed. However, legislation and guidance documents on the production and utilization of seaweed are generally still lacking. FAO and the World Health Organization (WHO) have therefore developed this report to identify food safety hazards (microbiological, chemical and physical) linked to the consumption of seaweed and aquatic plants. The present analysis could therefore provide a basis for undertaking further work in this area. Moreover, both FAO and WHO believe that there would be a value in developing relevant Codex guidance on this subject.

Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems for harmful algal blooms

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251377146
Total Pages : 224 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems for harmful algal blooms by : Food and Agriculture Organization of the United Nations

Download or read book Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems for harmful algal blooms written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2023-03-16 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, there are 3 400 to 4 000 described species of marine microalgae but only 1 to 2 percent are considered to be harmful. Harmful algal blooms (HABs) have significant impacts on food safety and security through contamination or mass mortalities of aquatic organisms. The impacts and mass mortalities of marine species caused by harmful algae are not new and have been recorded for decades. However, there is growing concern that these events will increase due to accelerating global warming, climate change and anthropogenic activities. Indeed, if not properly controlled, aquatic products contaminated with HAB biotoxins are responsible for potentially deadly foodborne diseases and when rapidly growing, HAB consequences include reduced dissolved oxygen in the ocean, dead zones, and mass mortalities of aquatic organisms. Improving HAB forecasting is an opportunity to develop early warning systems for HAB events such as food contamination, mass mortalities, or foodborne diseases. Surveillance systems have been developed to monitor HABs in many countries; however, the lead-time or the type of data (i.e. identification at the species-level, determination of toxicity) may not be sufficient to take effective action for food safety management measures or other reasons, such as transfer of aquaculture products to other areas. Having early warning systems could help mitigate the impact of HABs and reduce the occurrence of HAB events. The Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems (EWS) for HABs will guide competent authorities and relevant institutions involved in consumer protection or environmental monitoring to implement early warning systems for HABs present in their areas (marine and brackish waters), specifically those affecting food safety or food security (benthic HABs, fish-killing HABs, pelagic toxic HABs, and cyanobacteria HABs). The guidance provides a roadmap for stakeholders on how to improve or implement an EWS for HABs and biotoxins, where appropriate. It is important to note that not all countries and institutions can implement the same level of EWS for HABs, and this guidance is intended mainly for those who seek to broaden existing early warning systems, or who are just beginning to consider putting a system in place.

Risk assessment of food allergens

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251385793
Total Pages : 102 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Risk assessment of food allergens by : Food and Agriculture Organization of the United Nations

Download or read book Risk assessment of food allergens written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2024-02-08 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Codex Committee on Food Labelling (CCFL) requested scientific advice as to whether certain foods and ingredients, such as highly refined foods and ingredients, that are derived from the list of foods known to cause hypersensitivity can be exempted from mandatory declaration. The objective of this fourth meeting was to expand on the recommendations from the first meeting concerning derivatives of food allergens and establish a framework for evaluating exemptions for food allergens. A pro forma process has been developed and tested against allergen derivatives previously granted exemptions in various countries or regions and found to be effective for consideration in future exemption decisions. The Expert Committee recommends that the process outlined in the pro forma process be used to guide any future development and evaluation of derivative exemptions. Establishment of safety based upon this weight of evidence approach is dependent upon consideration of data quality, outcome of the exposure assessment for all intended ingredient uses (specified for exemption) and review by competent authorities (as needed). When safety is established, exemption can be justified.

Risk Assessment of Food Allergens – Part 5: Review and establish threshold levels for specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat and oats

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251382832
Total Pages : 48 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Risk Assessment of Food Allergens – Part 5: Review and establish threshold levels for specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat and oats by : Food and Agriculture Organization of the United Nations

Download or read book Risk Assessment of Food Allergens – Part 5: Review and establish threshold levels for specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat and oats written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2023-10-24 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Part 2 of the Ad hoc Joint FAO/WHO Expert Consultation on Risk Assessment of Food Allergens, reference doses (RfDs) were recommended for the global priority allergens, which included: walnut (and pecan), cashew (and pistachio), almond, peanut, egg, hazelnut, wheat, fish, shrimp, milk and sesame. Still, RfDs were not recommended for a number of regional or national priority allergens as they did not meet the criteria to be global priority allergens. In an additional request, the Codex Committee on Food Labelling (CCFL) indicated interest in potential RfD derivation for the following specific food allergens: specific tree nuts (Brazil nut, macadamia nut or Queensland nut, pine nut), soy, celery, lupin, mustard, buckwheat, and oats. An overview of the available data and recommended RfDs (or reasons no RfD could be derived) are given here for these specific food allergens. These RfDs were derived following the guidelines described in Part 2 of the Ad hoc Joint FAO/WHO Expert Consultation for deriving an RfD for priority allergenic foods. Details of the available data and discussions of the Expert Committee are presented in this report.

Illuminating Hidden Harvests

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251376824
Total Pages : 376 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Illuminating Hidden Harvests by : Food and Agriculture Organization of the United Nations

Download or read book Illuminating Hidden Harvests written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2023-03-15 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illuminating Hidden Harvests: the contributions of small-scale fisheries to sustainable development (hereinafter IHH) is a global study uncovering the contributions and impacts of small-scale fisheries through a multidisciplinary approach to data collection and analysis. The study provides information that quantifies and improves understanding of the crucial role of small-scale fisheries in the areas of food security and nutrition, sustainable livelihoods, poverty eradication and healthy ecosystems. It also examines gender equality as well as the nature and scope of governance in small-scale fisheries. The IHH study was carried out in support of the implementation of the Voluntary Guidelines for Securing Sustainable Small-Scale Fisheries in the Context of Food Security and Poverty Eradication (SSF Guidelines), themselves developed in recognition of the plight of small-scale fishers, fishworkers and associated communities and released as a contribution to the International Year of Artisanal Fisheries and Aquaculture 2022. The purpose of this report is to contribute to a more holistic understanding of what small-scale fisheries are, their importance, and why they are essential to efforts to achieve the Sustainable Development Goals (SDGs). By using this knowledge wisely within a human rights-based approach in line with the SSF Guidelines, and by empowering small-scale fishers and fishworkers, a more inclusive, equitable, sustainable and resilient small-scale scale fisheries subsector can be achieved. Realizing this goal would benefit hundreds of thousands in fishing communities and society at large. With this in mind, the IHH report is aimed at all those with a stake or an interest in the small-scale fisheries subsector, in particular decision-makers who are concerned with fisheries, poverty eradication, food security and nutrition, and sustainable development more generally. It is also addressed to small-scale fisheries actors themselves and those who support them.

FAO's work on climate change

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251339899
Total Pages : 79 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis FAO's work on climate change by : Food and Agriculture Organization of the United Nations

Download or read book FAO's work on climate change written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2021-05-06 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Food and Agriculture Organization of the United Nations (FAO) works towards ending hunger and poverty while using precious natural resources sustainably. The fisheries and aquaculture sector makes substantial contributions to food security, livelihoods and global trade. Global production of fish and other aquatic animals continued to grow and reached 179 million tonnes in 2018, and about 59.5 million people were engaged in the primary sector of capture fisheries and aquaculture. Fishery net exports generate significantly more revenue for developing countries than other agricultural commodities such as rice, coffee and tea. Millions of people are struggling to maintain reasonable livelihoods through the fisheries and aquaculture sector. These are the people who are the most vulnerable to the impacts of climate change. Climate change adds to the many threats and obstacles that already confront them in their day-to-day lives. Particular attention must be given to the most vulnerable if the sector is to continue to contribute to meeting global goals of poverty reduction and food security. This publication presents FAO’s work on climate change and fisheries and aquaculture. It includes examples of FAO’s support to countries so that they are better able to adapt to the impact of climate change in the fisheries and aquaculture sector. It also brings together FAO’s most up-to-date knowledge on climate change, including a portfolio of adaptation tools and measures used to support countries’ climate commitments and action plans.

Climate Change and Marine and Freshwater Toxins

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110625733
Total Pages : 669 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Climate Change and Marine and Freshwater Toxins by : Luis M. Botana

Download or read book Climate Change and Marine and Freshwater Toxins written by Luis M. Botana and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-12-16 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasingly widespread production of toxins by marine and freshwater microalgae raises serious concerns regarding seafood and drinking water safety. This book compiles studies on the influence of climate change on the spreading of toxin-producing species in aquatic systems. The chemistry and biology of toxin production is revised and an outlook on control and prevention of the toxins' impact on human and animal health is given.

FAO Publications Series 2021

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251341613
Total Pages : 84 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis FAO Publications Series 2021 by : Food and Agriculture Organization of the United Nations

Download or read book FAO Publications Series 2021 written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2021-04-08 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: FAO’s major publications series are presented together in a user-friendly catalogue. The catalogue features all of the most active series, both new and long-standing, and is divided into areas of work, including agriculture, forestry, fisheries, trade and investment, among others. Each series entry includes technical specifications, language versions, most recent titles, relevant ISSNs, and QR codes linking to online resources in the FAO Document Repository.

Oceans and Human Health

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Publisher : Elsevier
ISBN 13 : 0323952283
Total Pages : 834 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Oceans and Human Health by : Lora Fleming

Download or read book Oceans and Human Health written by Lora Fleming and published by Elsevier. This book was released on 2023-07-14 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oceans and Human Health: Opportunities and Impacts, Second Edition explores the inextricably interconnected and complex relationship between oceans and humans. Through the lens of the expanding oceans and human health meta-discipline, this work examines the many invaluable ecosystem services offered by oceans as well as the global anthropogenic impacts, and explores the associated risks and benefits to human health. Written and edited by an interdisciplinary team of experts, the book features international perspectives on the resources available to address these benefits and risks, including enhanced research, policy, and community engagement. The book concludes by examining the future of ocean stewardship and how global populations can unite to nurture and promote our life-enhancing relationship with oceans. This is an indispensable resource for students, researchers, communities, and industry specialists in marine sciences, public health, and international policy. Addresses benefits, opportunities, risks, and impacts resulting from the relationship between oceans and humans, informed by more than 100 international authors Identifies and links necessary tools to relevant disciplines for action, and provides illustrative international case studies Covers scientific, socioeconomic, political, and ethical analyses behind the latest ocean and human health research Provides study questions and horizon scans at the end of each chapter to encourage individual thought and action, offering a resource for course instructors, students, and communities

Environmental Toxicology

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111014444
Total Pages : 364 pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Environmental Toxicology by : Luis M Botana

Download or read book Environmental Toxicology written by Luis M Botana and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-03-18 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book about Non-bacterial toxins will cover those toxins that affect food safety and are produced by fungi (mycotoxins), cyanobacteria (cyanotoxins) and marine microalgae (phycotoxins). These three group of toxins affect food safety and drinking water quality at a global scale, and they pose three main challenges for scientists: 1) Climate change is causing a slow but steady change on the chemical profile of each of these groups, causing intoxications in areas that are geographically new to the intoxications map. For this reason, emerging toxins are a new topic that requires an important reallocation of resources to understand the new toxins trends, their toxicology, their analytical control and how to deal with them from a regulatory standpoint. 2) Toxicological science needs to be updated to determine the impact of the toxins in all kind of vectors (more and more are being discovered) and how they disseminate on the food chain. Also, the mode of action of many of this toxins is not understood or even known, and this affects also to the impact of the coexistence of several toxins in the same matrix. 3) Detection and regulation, as this requires the use of advance technology (mass spectrometry, biosensors, multitask screening etc) that is in many cases underdevelopped or not available, especially for many of the new toxins. Climate change, toxicology and detection affect so many areas of science that this book will try to keep the readers updated about the current state of the art.

Thinking about the future of food safety

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251357838
Total Pages : 158 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Thinking about the future of food safety by : Food and Agriculture Organization of the United Nations

Download or read book Thinking about the future of food safety written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2022-03-04 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Agrifood systems are undergoing a transformation with the aim to provide safer, more affordable, and healthier diets for all, produced in a sustainable manner while delivering just and equitable livelihoods: a key to achieving the UN’s 2030 Agenda for Sustainable Development. However, this transformation needs to be executed in the global context of major challenges facing the food and agriculture sectors, with drivers such as climate change, population growth, urbanization, and natural resources depletion compounding these challenges. Food safety is a keystone to agrifood systems and all food safety actors need to keep pace with the ongoing transformation while preparing to navigate the potential threats, disruptions, and challenges that may arise. Foresight in food safety facilitates the proactive identification of drivers and related trends, both within and outside agrifood systems, that have implications for food safety and therefore also for consumer health, the national economy, and international trade. Early identification and evaluation of drivers and trends promote strategic planning and preparedness to take advantage of emerging opportunities and address challenges in food safety. In this publication, the FAO Food Safety Foresight programme provides an overview of the major global drivers and trends by describing their implications for food safety in particular and for agrifood systems by extrapolation. The various drivers and trends reported include climate change, changing consumer behaviour and preferences, new food sources and production systems, technological advances, microbiome, circular economy, food fraud, among others. The intended audience for this publication is broad – from the policymakers, academia, food business operators, private sector, to all of us, the consumers.

Technical series on adapting to climate sensitive health impacts: diarrhoeal diseases

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Author :
Publisher : World Health Organization
ISBN 13 : 9240064591
Total Pages : 85 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Technical series on adapting to climate sensitive health impacts: diarrhoeal diseases by : World Health Organization

Download or read book Technical series on adapting to climate sensitive health impacts: diarrhoeal diseases written by World Health Organization and published by World Health Organization. This book was released on 2022-12-31 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Marine Biotoxins

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Publisher : Food & Agriculture Org.
ISBN 13 : 9789251051290
Total Pages : 300 pages
Book Rating : 4.0/5 (512 download)

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Book Synopsis Marine Biotoxins by : Hans P. Egmond

Download or read book Marine Biotoxins written by Hans P. Egmond and published by Food & Agriculture Org.. This book was released on 2004 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.

Ensuring Global Food Safety

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Publisher : Academic Press
ISBN 13 : 0128160128
Total Pages : 562 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Ensuring Global Food Safety by : Aleksandra Martinovic

Download or read book Ensuring Global Food Safety written by Aleksandra Martinovic and published by Academic Press. This book was released on 2022-02-10 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ensuring Global Food Safety: Exploring Global Harmonization, Second Edition, examines the policies and practices of food law which remain top contributors to food waste. This fully revised and updated edition offers a rational and multifaceted approach to the science-based issue of "what is safe for consumption?" and how creating a globally acceptable framework of microbiological, toxicological and nutritional standards can contribute to the alleviation of hunger and food insecurity in the world. Currently, many laws and regulations are so stringent that healthy food is destroyed based on scientifically incorrect information upon which laws and regulations are based. This book illuminates these issues, offering guidelines for moving toward a scientifically sound approach to food safety regulation that can also improve food security without putting consumers at risk. Presents the progress and current status of regulatory harmonization for food standards Provides a science-based foundation for global regulatory consensus Approaches challenges from a risk-benefit approach, also including safety assurance Includes global perspectives from governmental, academic and industry experts

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

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Publisher : Elsevier
ISBN 13 : 0323853587
Total Pages : 684 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Toxicological Risk Assessment and Multi-System Health Impacts from Exposure by : Aristidis M. Tsatsakis

Download or read book Toxicological Risk Assessment and Multi-System Health Impacts from Exposure written by Aristidis M. Tsatsakis and published by Elsevier. This book was released on 2021-08-01 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. • Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field • Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease • Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research

Hayes' Principles and Methods of Toxicology

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Publisher : CRC Press
ISBN 13 : 1000875776
Total Pages : 2143 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Hayes' Principles and Methods of Toxicology by : A. Wallace Hayes

Download or read book Hayes' Principles and Methods of Toxicology written by A. Wallace Hayes and published by CRC Press. This book was released on 2023-07-03 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.