Regulation Of Mrna Decay In Saccharomyces Cerevisiae By The Sequence Specific Rna Binding Protein Vts1

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Protein-Based Inheritance

Author : Dr. Yury O. Chernoff
Publisher : CRC Press
ISBN 13 : 1498712509
Total Pages : 154 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Protein-Based Inheritance by : Dr. Yury O. Chernoff

Download or read book Protein-Based Inheritance written by Dr. Yury O. Chernoff and published by CRC Press. This book was released on 2007-09-04 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a topic that has been neglected for years and has returned to the spotlight only recently. Until the genetic role of DNA was firmly established, many researchers suspected that proteins, rather than nucleic acids, could be carriers of heritable information. However, these models were completely forgotten with the triumphal march of the double helix and the development of a central dogma postulating that information flow occurs strictly from DNA, through RNA, to protein, making it seemingly impossible for the proteins to possess a coding potential. Proteins were downgraded to the role of simple perpetuators and executors of DNA orders. Taken together, data included in this book prove beyond a reasonable doubt that proteins and multiprotein complexes are able to control heritable traits, and that, at least in some examples, this control occurs in a template-like fashion, so that new structures strictly reproduce patterns of pre-existing structures that were not specifically coded in DNA. Thus, protein-based inheritance has left the area of speculation and has emerged as a new topic amenable to high-quality experimental analysis.

RNA-protein Interactions

Author : Kiyoshi Nagai
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis RNA-protein Interactions by : Kiyoshi Nagai

Download or read book RNA-protein Interactions written by Kiyoshi Nagai and published by Oxford University Press, USA. This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.

Dictyostelium

Author : Richard H. Kessin
Publisher : Cambridge University Press
ISBN 13 : 0521583640
Total Pages : 318 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Dictyostelium by : Richard H. Kessin

Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

Regulation of microRNAs

Author : Helge Großhans
Publisher : Springer
ISBN 13 : 9781441978240
Total Pages : 160 pages
Book Rating : 4.9/5 (782 download)

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Book Synopsis Regulation of microRNAs by : Helge Großhans

Download or read book Regulation of microRNAs written by Helge Großhans and published by Springer. This book was released on 2011-08-25 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book.

Control of Messenger RNA Stability

Author : Joel G. Belasco
Publisher : Elsevier
ISBN 13 : 008091652X
Total Pages : 537 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Control of Messenger RNA Stability by : Joel G. Belasco

Download or read book Control of Messenger RNA Stability written by Joel G. Belasco and published by Elsevier. This book was released on 2012-12-02 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive review of mRNA stability and its implications for regulation of gene expression. Written by experts in the field, Control of Messenger RNA Stability serves both as a reference for specialists in regulation of mRNA stability and as a general introduction for a broader community of scientists. - Provides perspectives from both prokaryotic and eukaryotic systems - Offers a timely, comprehensive review of mRNA degradation, its regulation, and its significance in the control of gene expression - Discusses the mechanisms, RNA structural determinants, and cellular factors that control mRNA degradation - Evaluates experimental procedures for studying mRNA degradation

Structures of Large RNA Molecules and Their Complexes

Author :
Publisher : Academic Press
ISBN 13 : 0128019360
Total Pages : 675 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Structures of Large RNA Molecules and Their Complexes by :

Download or read book Structures of Large RNA Molecules and Their Complexes written by and published by Academic Press. This book was released on 2015-06-06 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in RNA folding and dynamics, RNA-protein interactions and large RNPs. - Continues the legacy of this premier serial with quality chapters on structures of large RNA molecules and their complexes

Origin and Evolution of Viruses

Author : Esteban Domingo
Publisher : Elsevier
ISBN 13 : 0080564968
Total Pages : 573 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Origin and Evolution of Viruses by : Esteban Domingo

Download or read book Origin and Evolution of Viruses written by Esteban Domingo and published by Elsevier. This book was released on 2008-06-23 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. - NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution - UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups - SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

The Genome of Drosophila Melanogaster

Author : Dan L. Lindsley
Publisher : Academic Press
ISBN 13 : 0323139841
Total Pages : 1144 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Genome of Drosophila Melanogaster by : Dan L. Lindsley

Download or read book The Genome of Drosophila Melanogaster written by Dan L. Lindsley and published by Academic Press. This book was released on 2012-12-02 with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dedicated to the memory of George Lefevre in recognition of his exhaustive cytogenetic analysis of the X chromosome, The Genome of Drosophila melanogaster is the complete compendium of what is known about the genes and chromosomes of this widely used model organism. The volume is an up-to-date revision of Lindsley and Grell's 1968 work, Genetic Variations of Drosophila melanogaster. The new edition contains complete descriptions of normal and mutant genes including phenotypic, cytological, molecular, and bibliographic information. In addition, it describes thousands of recorded chromosome rearrangements used in research on Drosophila. This handbook and its accompanying polytene chromosome maps, are sturdily bound into the book as foldouts and available as a separate set, are essential research tools for the Drosophila community. - Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature - Describes normal chromosome complement, special chromosome constructs, transposable elements, departures from diploidy, satellite sequences, and nonchromosomal inheritance - Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the end of 1989 Contains the cytogenetic map of all genes as of mid-1991 - Contains the original polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the detailed maps of the chromosome arms produced by C.B. and P.M. Bridges - All maps are reprinted as high-quality foldouts sturdily bound into the volume - Maps may also be purchased separately in an eight-map packet, for laboratory and student use

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Author : Jan Gorodkin
Publisher : Humana
ISBN 13 : 9781627037082
Total Pages : 0 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods by : Jan Gorodkin

Download or read book RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods written by Jan Gorodkin and published by Humana. This book was released on 2014-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.

TDP-43 and Neurodegeneration

Author : Vijay Kumar
Publisher : Elsevier
ISBN 13 : 0128200669
Total Pages : 270 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis TDP-43 and Neurodegeneration by : Vijay Kumar

Download or read book TDP-43 and Neurodegeneration written by Vijay Kumar and published by Elsevier. This book was released on 2021-10-27 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside

Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding

Author : Daniel Herschlag
Publisher :
ISBN 13 :
Total Pages : 502 pages
Book Rating : 4.:/5 (891 download)

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Book Synopsis Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding by : Daniel Herschlag

Download or read book Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding written by Daniel Herschlag and published by . This book was released on 2009 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay

Author : Lynne E. Maquat
Publisher : Academic Press
ISBN 13 : 0080922074
Total Pages : 661 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay by : Lynne E. Maquat

Download or read book RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay written by Lynne E. Maquat and published by Academic Press. This book was released on 2009-01-30 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover, which are central to the process of gene expression - Offers step-by-step lab instructions, including necessary equipment and reagents

Emerging Model Organisms

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (699 download)

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Book Synopsis Emerging Model Organisms by :

Download or read book Emerging Model Organisms written by and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systems Genetics

Author : Florian Markowetz
Publisher : Cambridge University Press
ISBN 13 : 131638098X
Total Pages : 287 pages
Book Rating : 4.3/5 (163 download)

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Book Synopsis Systems Genetics by : Florian Markowetz

Download or read book Systems Genetics written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.

Natural and Engineered Resistance to Plant Viruses

Author : Michael Buchmeier
Publisher : Academic Press
ISBN 13 : 9780123745255
Total Pages : 269 pages
Book Rating : 4.7/5 (452 download)

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Book Synopsis Natural and Engineered Resistance to Plant Viruses by : Michael Buchmeier

Download or read book Natural and Engineered Resistance to Plant Viruses written by Michael Buchmeier and published by Academic Press. This book was released on 2010 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral hemorrhagic fevers (VHFs) are a group of illnesses that are caused by several distinct families of viruses. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause severe life-threatening disease. Some examples include: Lassa fever, Marburg virus, Ebola virus, Bolivian hemorrhagic fever, Korean hemorrhagic fever, Crimean-Congo hemorrhagic fever and Dengue hemorrhagic fever. No current treatment can cure viral hemorrhagic fevers, and immunizations exist for only two (yellow fever and Argentine hemorrhagic fever) of the many VHFs. Researchers are working to develop other vaccines, but in the meantime, the best approach is prevention. This volume will provide a review of what is known to date on these virus families as well as highlighting recent advances and future needs. Key features: * Provides comprehensive overview of what is known to date, recent advances and future needs * Examines transmission and risk factors * Highlights what has been done to help in outbreak control * Discusses the need for vaccines and antivirals

Chemistry for Green Environment

Author : M. M. Srivastava
Publisher : Alpha Science Int'l Ltd.
ISBN 13 : 9788173196201
Total Pages : 384 pages
Book Rating : 4.1/5 (962 download)

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Book Synopsis Chemistry for Green Environment by : M. M. Srivastava

Download or read book Chemistry for Green Environment written by M. M. Srivastava and published by Alpha Science Int'l Ltd.. This book was released on 2005 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of the current status of chemistry; regarding the implementation of clean, eco-friendly, less improvident manufacturing processes. This book acknowledges a more eco-conscious face of multi-dimensional chemistry: the need, principle, evolution, strategies and bioethical concerns for sustainable development of environment.

Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications

Author :
Publisher : Academic Press
ISBN 13 : 9780121822439
Total Pages : 517 pages
Book Rating : 4.8/5 (224 download)

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Book Synopsis Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications by :

Download or read book Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications written by and published by Academic Press. This book was released on 2001-10-05 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume on ribonucleases provides up-to-date, methods-related information on these enzymes. Of particular interest to researchers will be the discussion of artificial and engineered ribonucleases, as well as the application of ribonucleases in medicine and biotechnology. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.