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Author : Colleen Kay Smith
Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.3/5 (129 download)
Download or read book Regulation of Energy Balance and Body Composition in the Obese (ob/ob) Mouse written by Colleen Kay Smith and published by . This book was released on 1985 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : V. Daniel Castracane
Publisher : Springer Science & Business Media
ISBN 13 : 0387314164
Total Pages : 375 pages
Book Rating : 4.3/5 (873 download)
Download or read book Leptin written by V. Daniel Castracane and published by Springer Science & Business Media. This book was released on 2006-12-22 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an edited collection of the literature on leptin beginning with the discovery of leptin and a study of its affect on animals and in humans. Chapters will focus on the discovery, history, roles and regulation of leptin in all the major areas of physiology, as well as on assay methods, phylogeny and genetics. The timing of this volume is long overdue and is the first comprehensive coverage of leptin physiology in the field.
Author : Claude Bouchard
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)
Download or read book Regulation of Body Weight written by Claude Bouchard and published by . This book was released on 1996-06-19 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fact that about 30-40% of the adults in the Western world are overweight or obese testifies to the frequency of the disturbances in body weight regulation. Scientists have established that caloric intake, macronutrient composition of the diet, basal and resting metabolic rate, thermic response to food, energy expenditure associated with movement and physical activity, and preferential storage of the surplus of calories as fat or lean tissues are critical determinants of energy balance and body weight. While much has been learned, the field is poised for major advances with the advent of a variety of imaging techniques, progress in quantitative and molecular genetics, use of transgenic rodent models and of breeding experiments with informative inbred strains, availability of stable isotopes for metabolic and behavioral studies, and a growing number of useful experimental animal and human models. This volume takes an integrative approach to obesity. It is structured around four major topics: (1) the animal and human models currently available for the study of body weight regulation with their strengths and limitations, (2) the molecular and genetic basis of the regulation of body weight, (3) the metabolic and physiological mechanisms involved, and (4) the behavioral and social determinants. The 13 background papers provide a critical overview of the present knowledge base while the group reports summarize the extensive deliberations of 38 international experts. Particular emphasis has been given to promising research areas and on the advances needed to ensure a better understanding of the biological and behavioral mechanisms of the regulation of body weight, with a particular emphasis on overweight and obesity.
Author : Pi-Yao Lin
Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.3/5 (129 download)
Download or read book Food Intake, Body Weight Gain, and Body Composition of the Young Obese (ob/ob) Mouse written by Pi-Yao Lin and published by . This book was released on 1977 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Isabelle Romieu
Publisher : IARC Working Group Report
ISBN 13 : 9789283225195
Total Pages : 0 pages
Book Rating : 4.2/5 (251 download)
Download or read book Energy Balance and Obesity written by Isabelle Romieu and published by IARC Working Group Report. This book was released on 2018-01-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the relationship between energy balance and obesity is essential to develop effective prevention programs and policies. The International Agency for Research on Cancer convened a Working Group of world-leading experts in December 2015 to review the evidence regarding energy balance and obesity, with a focus on low- and middle-income countries, and to consider the following scientific questions: (i) Are the drivers of the obesity epidemic related only to energy excess and/or do specific foods or nutrients play a major role in this epidemic? (ii) What are the factors that modulate these associations? (iii) Which types of data and/or studies will further improve our understanding? This book provides summaries of the evidence from the literature as well as the Working Group's conclusions and recommendations to tackle the global epidemic of obesity.
Author :
Publisher :
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.E/5 ( download)
Download or read book Regulation of Energy Balance in Man written by and published by . This book was released on 1975 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Wolfgang Meyerhof
Publisher : Springer Science & Business Media
ISBN 13 : 3642144268
Total Pages : 205 pages
Book Rating : 4.6/5 (421 download)
Download or read book Sensory and Metabolic Control of Energy Balance written by Wolfgang Meyerhof and published by Springer Science & Business Media. This book was released on 2010-09-24 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, the prevalence of obesity has dramatically increased in western and westernized societies. Its devastating health consequences include hypertension, cardiovascular diseases, or diabetes and make obesity the second leading cause of unnecessary deaths in the USA. As a consequence, obesity has a strong negative impact on the public health care systems. Recently emerging scienti?c insight has helped understanding obesity as a complex chronic disease with multiple causes. A multileveled gene–environment interaction appears to involve a substantial number of susceptibility genes, as well as associations with low physical activity levels and intake of high-calorie, low-cost, foods. Unfor- nately, therapeutic options to prevent or cure this disease are extremely limited, posing an extraordinary challenge for today’s biomedical research community. Obesity results from imbalanced energy metabolism leading to lipid storage. Only detailed understanding of the multiple molecular underpinnings of energy metabolism can provide the basis for future therapeutic options. Numerous aspects of obesity are currently studied, including the essential role of neural and endocrine control circuits, adaptive responses of catabolic and anabolic pathways, metabolic fuel sensors, regulation of appetite and satiation, sensory information processing, transcriptional control of metabolic processes, and the endocrine role of adipose tissue. These studies are predominantly fuelled by basic research on mammalian models or clinical studies, but these ?ndings were paralleled by important insights, which have emerged from studying invertebrate models.
Author : Gema Frühbeck
Publisher : CABI
ISBN 13 : 1845934075
Total Pages : 410 pages
Book Rating : 4.8/5 (459 download)
Download or read book Peptides in Energy Balance and Obesity written by Gema Frühbeck and published by CABI. This book was released on 2009 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide an updated, detailed and comprehensive account of the field through a cutting-edge analysis by leading experts in the area. To achieve this, the book is divided into three parts, focusing on the peptides operating both centrally and peripherally at the same time as providing an integral and integrated perspective of the multifaceted and complex regulation of energy balance homeostasis. Part I contains three chapters covering the central pathways involved in the control of food intake. The first of these is devoted to the orexigenic neuropeptides, i.e. those that increase or stimulate appetite, while the second is a description of the peptides with anorexigenic effects, i.e. those that decrease or stop food intake. Since this is a rapidly evolving field, the third chapter concentrates on emerging and newly identified factors and their interaction with the already well-known peptides. Part II encompasses six chapters that deal with the peripheral signals participating in energy homeostasis and their control in health and disease. Regulation of body weight was once considered a simple feedback control system in which the hypothalamus modulated food intake and energy expenditure to compensate for fluctuations in body weight. The existing body of evidence has fostered the transition from the classic adipostat, a sensor of body adiposity that informs the hypothalamus about the abundance of energy stores, to a more dynamic and multifactorial model including signals emerging from several different organs such as the gut, the liver, the pancreas and the vascular system. The underlying molecular mechanisms by which adipose tissue enlargement and the subsequent increase in adipokines contribute to the pathophysiological events in the gastrointestinal, hepatic, pancreatic, musculoskeletal, cardiovascular and immune systems are now beginning to be better understood and are covered in detail in this section of the book. Part III contains six chapters providing an integrative approach to current knowledge in energy balance regulation. Adipose tissue biology and the hierarchy of the neural circuitry controlling energy homeostasis deserve special attention, as does the relevance of food reward signals and the links between the homeostatic and hedonic systems. Specific chapters address the available advances in technology to analyse these complex issues, including functional neuroimaging and the whole range of the 'omics' strategies. The final chapter takes a fresh and innovative look at future potential approaches to obesity management.
Author : Frank P. Brooks
Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)
Download or read book Endocrinology of the Gut written by Frank P. Brooks and published by . This book was released on 1974 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lara Elisabeth Warren
Publisher :
ISBN 13 :
Total Pages : 498 pages
Book Rating : 4.:/5 (66 download)
Download or read book Effects of Gravity on Energy Balance in Rats written by Lara Elisabeth Warren and published by . This book was released on 2003 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : George A. Bray
Publisher : CRC Press
ISBN 13 : 020391337X
Total Pages : 1064 pages
Book Rating : 4.2/5 (39 download)
Download or read book Handbook of Obesity written by George A. Bray and published by CRC Press. This book was released on 2003-12-09 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering perspectives on the history, prevalence and genetics of obesity, this book examines the origins and etiology of obesity. It considers the relationship between behavioural neuroscience and obesity.
Author : Maria Moreno
Publisher : Frontiers Media SA
ISBN 13 : 2889198855
Total Pages : 119 pages
Book Rating : 4.8/5 (891 download)
Download or read book Hormonal and Neuroendocrine Regulation of Energy Balance written by Maria Moreno and published by Frontiers Media SA. This book was released on 2016-07-18 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alteration in adequate energy balance maintenance results in serious disturbances such as obesity and its related metabolic disorders. In Mammals, energy balance is homeostatically controlled through hormonal and neuroendocrine systems which cooperation is based on cross-talk between central and peripheral signals. The hypothalamus as well as peripheral hormones among which adipokines from adipose tissue and thyroid hormones play a crucial role in energy homeostasis. Unraveling the physiological, cellular and molecular mechanisms through which hormonal and neuroendocrine systems regulate energy balance has been a long-standing challenge in biology and is now more necessary when considering the world-wide increasing prevalence of obesity. Indeed, recognizing and understanding the biochemical and nutrient signaling pathways contributing to the nervous and endocrine integration of physiological mechanisms involved in the normal and/or abnormal regulation of energy balance is fundamental also to the development of new, effective, and targeted treatments for obesity. Recent studies have highlighted the role of hypothalamic pro-opiomelanocortin-expressing neurons in the regulation of energy homeostasis by controlling energy expenditure and food intake. This is accomplished through a precise balance of production and degradation of a-melanocyte-stimulating hormone, an anorexigenic neuropeptide which is degraded to an inactive form unable to inhibit food intake by the key enzyme prolyl carboxypeptidase (PRCP), thus suggesting that pharmacologic approaches targeting PRCP may provide a novel and effective option for the management of obesity and its associated metabolic disorders. Indeed, efforts have been made to generate potent, brain-penetrant PRCP inhibitors. Weight loss due to negative energy balance is a goal for obese subjects not always reachable by dietary caloric restriction or increased physical activity. Lipid-lowering therapies have been suggested to have potential benefits, however, the establishment of comprehensive therapeutic strategies is still awaited. Recently, it has been reported that thyroid hormone (TH)- derivatives such as 3,5-diiodothyronine and 3-iodothyronamine possess interesting biological activities, opening new perspectives in thyroid physiology and TH derivatives therapeutic usage. Moreover, several studies, focusing on the interaction between thyroid hormone (TH), the autonomic nervous system and the liver, revealed an important role for the hypothalamus in the differential effects of TH on autonomic outflow to peripheral organs controlling energy balance. This Research Topic aims to give a comprehensive and integrate view of the factors involved in the endocrine and neuroendocrine signaling in energy balance regulation to highlight their involvement into physiological processes and regulatory systems as well as their perturbation during pathological processes.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Author : Michelle Jane Robartson
Publisher :
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.:/5 (131 download)
Download or read book The Effects of Dietary Fats and Voluntary Exercise on Energy Balance and Body Composition in Laboratory Mice written by Michelle Jane Robartson and published by . This book was released on 1992 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ashli Thomas
Publisher :
ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.:/5 (17 download)
Download or read book Acute Effects of Caloric Intake and Macronutrient Type on Body Weight, Body Composition, Resting Energy Expenditure, and Total Metabolic Rate written by Ashli Thomas and published by . This book was released on 2006 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a growing epidemic with no consensus regarding solutions. Thirty healthy overweight and obese female subjects (41.9 " 12 years, 166 cm " 7 cm, a 100.5 kg " 19.6 kg, 46.0% " 4.0% body fat, and BMI 37.4 " 6.9) participated in the study. A 14-day dietary intervention examined acute effects of energy balance and macronutrient type on dietary intake, REE, body weight, body composition, and thyroid panel. Significant changes occurred in weight loss over time (p
Author : Andrea Dunaif
Publisher : Springer Science & Business Media
ISBN 13 : 1597451088
Total Pages : 361 pages
Book Rating : 4.5/5 (974 download)
Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Author :
Publisher : Elsevier
ISBN 13 : 044459454X
Total Pages : 513 pages
Book Rating : 4.4/5 (445 download)
Download or read book The Neurobiology of Circadian Timing written by and published by Elsevier. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
