Receptor-Mediated Binding and Internalization of Toxins and Hormones

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Author :
Publisher : Elsevier
ISBN 13 : 0323141331
Total Pages : 389 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Receptor-Mediated Binding and Internalization of Toxins and Hormones by : John Middlebrook

Download or read book Receptor-Mediated Binding and Internalization of Toxins and Hormones written by John Middlebrook and published by Elsevier. This book was released on 2012-12-02 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptor-Mediated Binding and Internalization of Toxins and Hormones presents the proceedings of a conference conducted for the purpose of exploring relationships between hormones and toxins, specifically, receptor-mediated internalization of toxins and hormones and the role of this internalization in message transmission and biodegradatory processes. This book is divided into three sections, with the first focusing on model systems of internalization. It presents pictorial illustrations of the receptor-mediated endocytosis of low-density lipoprotein via coated regions of membrane and discusses the receptor for lysosomal enzymes on the surface of cultured fibroblasts. The second section focuses on toxins and hormones and discusses such topics as receptor-mediated internalization of diphtheria toxin, diphtheria toxin interactions with an inhibitory activity from plasma membranes, and uptake mechanisms for ADP-ribosylating toxins. The third and final section focuses on hybrids and discusses such topics as chimeric toxins containing fragment A from diphtheria toxin, directed entry of hybrid proteins into cells via alternate receptors, and a hybrid protein of monoclonal anti-THY 1.2 and diphtheria toxin fragment A. This book will be of interest to practitioners in the fields of endocrinology, cell biology, and molecular genetics.

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1174 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1174 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Immunotoxins

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Publisher : Springer Science & Business Media
ISBN 13 : 1461310830
Total Pages : 550 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Immunotoxins by : Arthur E. Frankel

Download or read book Immunotoxins written by Arthur E. Frankel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Published Scientific Papers of the National Institutes of Health

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Publisher :
ISBN 13 :
Total Pages : 480 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Published Scientific Papers of the National Institutes of Health by : National Institutes of Health (U.S.)

Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.) and published by . This book was released on 1982 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue lists papers published during the preceding year.

Scientific Directory and Annual Bibliography

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Scientific Directory and Annual Bibliography by : National Institutes of Health (U.S.)

Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1982 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Receptor Regulation

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Publisher : Springer Science & Business Media
ISBN 13 : 146132131X
Total Pages : 446 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Mechanisms of Receptor Regulation by : George Poste

Download or read book Mechanisms of Receptor Regulation written by George Poste and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is less than 80 years since John Newport Langley first proposed the role of "receptive substances" as the site of drug action from his obser vations on the effects of nicotine and curare at the myoneural junction. The many advances in our understanding of receptor biology that have occurred during the intervening period mirror the extraordinary growth of knowledge in the biological sciences and in cell and molecular biology in particular. Receptor biology, in common with many other topics in contemporary biology, is on the threshold of a transition from being a descriptive, phenomenological discipline to one in which underlying mechanisms and regulatory principles can be defined with increasing pre cision. This change, together with the evolution of powerful analytical techniques and timely convergence of ideas from a number of previously separate fields of inquiry, is generating an increasingly unified theoretical and experimental framework for the study of receptor function. These themes, and the mood of anticipation that a real understanding of receptor function in health and disease is emerging, are reflected in in this volume, which summarizes the proceedings of the Sec the papers ond Smith Kline & French Research Symposium on New Horizons in Therapeutics held in Philadelphia in 1984.

Handbook of Natural Toxins

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Publisher : CRC Press
ISBN 13 : 9780824778408
Total Pages : 510 pages
Book Rating : 4.7/5 (784 download)

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Book Synopsis Handbook of Natural Toxins by : M. Carolyn Hardegree

Download or read book Handbook of Natural Toxins written by M. Carolyn Hardegree and published by CRC Press. This book was released on 1988-08-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4.

Investigation of Membrane-Located Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 1468446312
Total Pages : 542 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Investigation of Membrane-Located Receptors by : Eric Reid

Download or read book Investigation of Membrane-Located Receptors written by Eric Reid and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prefaces tend to be platitudinous and unconducive to perusal. To this hardened Editor, the appearance of the book represents the end of a stamina-testing saga surpassing any past experience. Amongst the numerous authors - a notably eminent bevy - some were angelic and others suffered harassment to produce, amidst day-to-day pressures, an eventual article in the cause of receptor investigation; few took exception to the strong editing that their material underwent. The reader of this book will be interested rather in its aims and ba- ground.- Does it merit a n his bookshelf? The book is not a 'Proceedings', but has sponsored-meeting parentage. Wi th company support, notably from BetaHED Pharmaceuti cals of Indianapolis, the 8th International Subcellular Hethodology Forum was held in July 1982 at the University of Surrey in Guildford. The vigorous debates, partly on aspects such as hormonal receptors and drug targeting, then narrowed to Neuroreceptor Hethodology at a NATO Advanced Research Workshop, perforce set up at short notice. But 'Proceedings' are proverbially ephemeral material reflecting an array of solo performances, whereas this book is hopefully more like an orchestra's performance, of classical together with new material. Retrievability of receptor 'know-how' has been a key aim. Locations in the text, including comments and supplementary material (designated 'NC'), are thoroughly indexed, whilst for some aspects a 'Retrieval Key' (p. 545) should be used. Related to receptor methodo logy, receptor features and phenomena get due attention in the text.

Tracer Kinetics and Physiologic Modeling

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Publisher : Springer Science & Business Media
ISBN 13 : 3642500366
Total Pages : 518 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Tracer Kinetics and Physiologic Modeling by : R.M. Lambrecht

Download or read book Tracer Kinetics and Physiologic Modeling written by R.M. Lambrecht and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Progress Report

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Annual Progress Report by :

Download or read book Annual Progress Report written by and published by . This book was released on with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diarrhea and Malnutrition

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Publisher : United Nations University Press
ISBN 13 : 9780306410468
Total Pages : 334 pages
Book Rating : 4.4/5 (14 download)

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Book Synopsis Diarrhea and Malnutrition by : Lincoln C. Chen

Download or read book Diarrhea and Malnutrition written by Lincoln C. Chen and published by United Nations University Press. This book was released on 1983-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are several reasons why a consolidation of recent advances in our understanding of the interaction of diarrhea and malnutrition is indi cated and timely. It is now widely recognized that diarrhea is a major cause of morbidity and mortality among children of poor countries. Due to recent advances in laboratory and field diagnostic techniques, many of the previously unrecognized etiologic agents responsible for diarrhea have been identified, thereby providing new scientific knowledge for rational control strategies. Increasingly these advances suggest that the morbidity burden of diarrhea may be of equal, if not greater, public health consequence than mortality. Diarrhea only rarely causes disease severe enough to require institutionalized medical care. The vast major ity of diseases are of mild or moderate severity, and because of high prev alence, diarrhea imposes an enormous morbidity burden and exerts a sig nificant negative impact on child growth and development. Moreover, the effects of successive episodes of diarrhea are likely to be cumulative. In contrast to several other childhood infections, the treatment of the diarrheal diseases is feasible because it uses simple, effective, and low cost medical technologies. Within the context of these developments, there has been a major resurgence of international interest in, and commitment to, the control of the diarrheal diseases. The World Health Organization recently has launched a global program for the control of diarrhea, and simulta neously, an independent international research center on diarrhea has been established in Bangladesh.

Diarrhea and Malnutrition

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461592844
Total Pages : 317 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Diarrhea and Malnutrition by : Lincoln Chen

Download or read book Diarrhea and Malnutrition written by Lincoln Chen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are several reasons why a consolidation of recent advances in our understanding of the interaction of diarrhea and malnutrition is indi cated and timely. It is now widely recognized that diarrhea is a major cause of morbidity and mortality among children of poor countries. Due to recent advances in laboratory and field diagnostic techniques, many of the previously unrecognized etiologic agents responsible for diarrhea have been identified, thereby providing new scientific knowledge for rational control strategies. Increasingly these advances suggest that the morbidity burden of diarrhea may be of equal, if not greater, public health consequence than mortality. Diarrhea only rarely causes disease severe enough to require institutionalized medical care. The vast major ity of diseases are of mild or moderate severity, and because of high prev alence, diarrhea imposes an enormous morbidity burden and exerts a sig nificant negative impact on child growth and development. Moreover, the effects of successive episodes of diarrhea are likely to be cumulative. In contrast to several other childhood infections, the treatment of the diarrheal diseases is feasible because it uses simple, effective, and low cost medical technologies. Within the context of these developments, there has been a major resurgence of international interest in, and commitment to, the control of the diarrheal diseases. The World Health Organization recently has launched a global program for the control of diarrhea, and simulta neously, an independent international research center on diarrhea has been established in Bangladesh.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1184 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Critical Reviews in Tropical Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1461334241
Total Pages : 568 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Critical Reviews in Tropical Medicine by : R. K. Chandra

Download or read book Critical Reviews in Tropical Medicine written by R. K. Chandra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous economic, sociocultural, and health problems continue to impede the optimal progress of many millions of people in the developing countries in tropical and other geographic regions of the world. Thus, tropical medicine has many aspects including parasitology, bacteriology, and virology, environmental sanitation and hygiene, nutrition, pharmacology, immunology, agriculture, eco nomics, political science, anthropology, sociology, and behavioral sciences. Like the mythical Proteus, the individual dealing with tropical medicine must assume many roles. There is a growing recognition of the unique problems of the tropical countries. This has led to concerted efforts by many international agencies to attempt to obtain new tools to control many of the tropical diseases that have defied previous attempts at large-scale control. The involvement of the world's leading scientists and institutions as well as the best talents and resources of the developing countries themselves has inspired considerable research in tropical medicine with an inevitable exponential growth in publications. The new series Critical Reviews in Tropical Medicine is being launched to provide topical state of-the-art critiques of selected subjects in this burgeoning field. Authored by active investigators in their chosen topics, these reviews should be useful for all health professionals, social scientists, and administrators involved in planning interventions, both preventive and therapeutic, in developing regions of the world. Contributions included in Volume 1 span parasitology, infectious disease, immunology, gastroenterology, liver disease, and nutrition.

Pediatric Tumors

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Publisher : CRC Press
ISBN 13 : 1000141926
Total Pages : 202 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Pediatric Tumors by : John T. Kemshead

Download or read book Pediatric Tumors written by John T. Kemshead and published by CRC Press. This book was released on 2020-10-28 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph explains the considerable impact that monoclonal antibodies and molecular probes have had on the diagnosis of tumor types and sub-types. It explains how radiolabelled monoclonal antibodies have also been used as imaging agents to try to improve the oncologist's ability to define residual tumor deposits after combination chemo/radiotherapy. Finally, the childhood malignancies that still have a poor prognosis are presented, and new novel ways of therapy are explained.

Annual Progress Report

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Annual Progress Report by : U.S. Army Medical Research Institute of Infectious Diseases

Download or read book Annual Progress Report written by U.S. Army Medical Research Institute of Infectious Diseases and published by . This book was released on 1980 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Progress Report - U. S. Army Medical Research Institute of Infectious Diseases

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Author :
Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Annual Progress Report - U. S. Army Medical Research Institute of Infectious Diseases by : U.S. Army Medical Research Institute of Infectious Diseases

Download or read book Annual Progress Report - U. S. Army Medical Research Institute of Infectious Diseases written by U.S. Army Medical Research Institute of Infectious Diseases and published by . This book was released on 1980 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: