Recent Advances in the Research of Plant-Derived Anti-Fungal Compounds

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Author :
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783659485534
Total Pages : 108 pages
Book Rating : 4.4/5 (855 download)

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Book Synopsis Recent Advances in the Research of Plant-Derived Anti-Fungal Compounds by : Alice Grigore

Download or read book Recent Advances in the Research of Plant-Derived Anti-Fungal Compounds written by Alice Grigore and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elaboration of medicines based on herbal compounds is a potential answer to the desideratum of The World Health Organization concerning the necessity of new therapeutic strategies. Studies concerning the anti-fungal action of certain plant-derived compounds confirm the modern medicine trend of searching for new chemical substances with therapeutic potential using natural sources. Discovering of new anti-fungal agents that are both long-term efficient and safe, causing no side effects is a general desiderate, especially in the modern era when diseases become more and more aggressive. Recent laboratory studies proved the huge potential of herbal compounds in inhibiting diseases caused by various fungi, alone or in combination with standard anti-fungal agents. Even if the mechanism of action of herbal active compounds is not completely understood yet and some pharmacokinetic issues need to be elucidated, the use of plant-derived compounds should be regarded as a future strategy for counteracting fungal diseases.

Recent Trends in Antifungal Agents and Antifungal Therapy

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Author :
Publisher : Springer
ISBN 13 : 8132227824
Total Pages : 254 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Recent Trends in Antifungal Agents and Antifungal Therapy by : Amit Basak

Download or read book Recent Trends in Antifungal Agents and Antifungal Therapy written by Amit Basak and published by Springer. This book was released on 2016-09-21 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students.

Plant-Derived Antimycotics

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Author :
Publisher : CRC Press
ISBN 13 : 9781560229278
Total Pages : 622 pages
Book Rating : 4.2/5 (292 download)

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Book Synopsis Plant-Derived Antimycotics by : M.k. Rai

Download or read book Plant-Derived Antimycotics written by M.k. Rai and published by CRC Press. This book was released on 2003-05-29 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important overview of the state of the art in naturally occurring antimycotics! Here is a comprehensive and innovative examination of the antimycotic potential of essential plant oils and extracts against fungal infections affecting humans, animals, plants, and foodstuffs. Plant-Derived Antimycotics emphasizes the antimycotic activity of plants found in Central America, India, Nepal, Fiji, and China--areas rich in phyto-diversity and traditional botanical/medical knowledge. From editor M.K. Rai: “Since the inception of human civilization men have been using herbs against various mycotic infections. In the recent past, several antimycotic agents have been introduced into the market due to their rapid curative properties. Still, the quest for new antifungal agents of a fungicidal rather than fungistatic nature continues. Furthermore, there has been a dramatic increase in the new spectrum of fungal infections known as opportunistic fungal pathogens. Consequently, plant-derived antimycotics are gaining importance, being natural, cheaper, safer, eco-friendly, and within the reach of the common man.” With a distinguished list of contributors from around the world, Plant-Derived Antimycotics explores: antifungal compounds that strengthen plant-defense systems traditional herbs that have revealed their antifungal properties newer, faster methods of screening and evaluating antifungal drugs natural antimycotics derived from plants in Croatia, South America, South Africa, China, India, and Fiji the mechanism of herbal antimycotic action the diversity of antimycotic efficacy in Asteraceous and Meliaceous plants new bioactive antifungal molecules Plant-Derived Antimycotics is an essential reference for pharmacologists, microbiologists, clinical mycologists, oncologists, immunologists, drug manufacturers, botanists and ethnobotanists, phytochemists, herbalists, and everyone searching for a natural remedy for the new spectrum of opportunistic fungal infections generated by the immunocompromising difficulties encountered by AIDS and cancer patients. Color illustrations, photographs, charts, tables, and graphs make the information easier to absorb and understand.

Medicinal Plants

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Publisher : BoD – Books on Demand
ISBN 13 : 1789858879
Total Pages : 194 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Medicinal Plants by : Bassam Hassan

Download or read book Medicinal Plants written by Bassam Hassan and published by BoD – Books on Demand. This book was released on 2020-03-25 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is focused on clarifying the anticancer effects (i.e., apoptotic, antiproliferative, antimetastatic, antiangiogenic) and mechanisms of most of the medicinal plants found in the world against solid and/or hematological cancers.

Advances in Antifungal Drug Development

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Publisher : Springer
ISBN 13 : 9789819751648
Total Pages : 0 pages
Book Rating : 4.7/5 (516 download)

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Book Synopsis Advances in Antifungal Drug Development by : Nikhat Manzoor

Download or read book Advances in Antifungal Drug Development written by Nikhat Manzoor and published by Springer. This book was released on 2024-09-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the antifungal properties of natural products and reviews their antifungal mechanism. An introductory chapter illustrates the various fungal pathogenic species, common fungal diseases, and general mechanisms of action of various antifungal classes, including natural products. The book comprises seven sections and each section contains chapters on the efficacy and antifungal mode of action of plant extracts, essential oils, natural compounds, their derivatives, and plant-based nanoparticles. A section summarizes the antifungal efficacy of compounds derived from sources other than plants, like microbes. Besides compound toxicity, the book explores the antifungal mode of action and efficacy against the virulence and pathogenicity of fungal pathogens like Candida, Aspergillus, Cryptococcus, Histoplasma, and other pathogenic fungi. Further, the book also describes recent advancements in the discovery of novel drug targets and therapeutic strategies that are non-toxic and more efficacious for combating drug resistance. This book is an invaluable source for researchers working in the field of fungal biochemistry, anti-microbial, and anti-bacterial and undergraduate and postgraduate students of microbiology and pharmacology.

Preparative Chromatography Techniques

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Publisher : Springer Science & Business Media
ISBN 13 : 3662036312
Total Pages : 259 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Preparative Chromatography Techniques by : K. Hostettmann

Download or read book Preparative Chromatography Techniques written by K. Hostettmann and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few years, increasing attention has been paid to the search for bioactive compounds from natural sources. The success of plant-derived products such as paclitaxel (Taxol) in tumor therapy or artemisinin in the treatment of malaria has provided the impetus for the introduction of numerous research programmes, especially in Industry. A great deal of effort is being expended in the generation of novel lead molecules of vegetable, marine and microbial origin by the use of high throughput screening protocols. When interesting hits are found, it is essen tial to have methods available for the rapid isolation of target compounds. For this reason, both industry and academia need efficient preparative chromatographic separation techniques and experience in their application. Purified natural products are required for complete spectro scopic identification and full characterization of new compo unds, for biological testing and for the supply of pharmaceuti cals, standards, and starting materials for synthetic work. Obtaining pure products from an extract can be a very long, te dious and expensive undertaking, involving many steps. Sometimes only minute amounts of the desired compounds are at hand and these entities may be labile. Thus it is an advantage to have access to as many different methods as possible in order to aid the isolation process. Although a certain amount of trial and error may be involved, nowadays there is the possibility of devising suitable rapid separation schemes by a judicious choice of the different techniques available.

The Microbiology of Skin, Soft Tissue, Bone and Joint Infections

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Author :
Publisher : Academic Press
ISBN 13 : 0128110937
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Microbiology of Skin, Soft Tissue, Bone and Joint Infections by : Kateryna Kon

Download or read book The Microbiology of Skin, Soft Tissue, Bone and Joint Infections written by Kateryna Kon and published by Academic Press. This book was released on 2017-04-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Microbiology of Skin, Soft Tissue, Bone and Joint Infections: Volume 2 discusses modern approaches in diagnosis, treatment, and prophylaxis of skin, soft tissue, bone, and joint infections. The volume has been divided into three sections. The first section includes chapters on diagnosis, treatment, and prophylaxis of skin and soft tissue infections. It discusses antimicrobial and surgical treatment of wounds, diabetic foot, and different soft tissue infections. Ten chapters are devoted to cutaneous and musculoskeletal infections in special groups of patients, which have their own specificity, i.e. in pediatric and HIV-infected patients. Together with chapters on commonly present diseases, there are chapters which discuss interesting but not well studied pathologies (natal cleft pilonidal sinus) and pathogens (Malassezia and Shewanella spp.). The second section reviews etiology, pathogenesis, diagnosis and treatment of bone and joint infections, mainly osteomyelitis and prosthetic joint infections. Also, one chapter in this section discusses a newly emerging bacterial pathogen that causes skeletal infections, Kingella kingae. The third section incorporates alternative and new approaches—such as nanotechnology, ultrasound, novel delivery approaches and phyto-derived medicines—to the treatment and prophylaxis of skin, soft tissue, bone, and joint infections. Encompasses a broad range of skin, soft tissue, bone, and joint infections, including questions of etiology, pathogenesis, diagnosis, prognosis, treatment, and prophylaxis Written by highly professional and eminent surgeons, microbiologists, and infectious disease specialists Discusses topics using modern insight, providing all necessary scientific information on each aspect Includes scientific understanding and practical guidelines, which make it interesting for both research scientists and practitioners working with skin, soft tissue, bone, and joint infections

Medicinal Plants and Fungi: Recent Advances in Research and Development

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Author :
Publisher : Springer
ISBN 13 : 9811059780
Total Pages : 557 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Medicinal Plants and Fungi: Recent Advances in Research and Development by : Dinesh Chandra Agrawal

Download or read book Medicinal Plants and Fungi: Recent Advances in Research and Development written by Dinesh Chandra Agrawal and published by Springer. This book was released on 2017-11-03 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest international research on different aspects of medicinal plants and fungi. Studies over the last decade have demonstrated that bioactive compounds isolated from medicinal fungi have promising antitumor, cardiovascular, immunomodulatory, anti-allergic, anti-diabetic, and hepatoprotective properties. In the light of these studies, the book includes chapters (mostly review articles) by eminent researchers from twelve countries across the globe working in different disciplines of medicinal plants and fungi. It discusses topics such as the prevention of major neurodegenerative and neurotoxic mechanisms by Centella asiatica; the medicinal properties and therapeutic applications of several mushrooms species found in different parts of the world; and fungal endophytes as a source of bioactive metabolites including anticancer and cardioprotective agents. There are also chapters on strategies for identifying bioactive secondary metabolites of fungal origin; the use of genomic information to explore the biotechnological potential of medicinal mushrooms; and solid state fermentation of agro-industrial and forestry residues for the production of medicinal mushrooms. It is a valuable resource for the researchers, professionals and students working in the area of medicinal plants and fungi.

Yeast Membrane Transport

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Publisher : Springer
ISBN 13 : 3319253042
Total Pages : 381 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Yeast Membrane Transport by : José Ramos

Download or read book Yeast Membrane Transport written by José Ramos and published by Springer. This book was released on 2015-12-31 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume reviews the recent progress in our understanding of membrane transport in yeast including both Saccharomyces cerevisiae and non-conventional yeasts. The articles provide a summary of the key transport processes and put these in a systems biology context of cellular regulation, signal reception and homeostasis. After a general introduction, readers will find review articles covering the mechanisms and regulation of transport for various substrates ranging from diverse nutrients to cations, water and protons. These articles are complemented by a chapter on extremophilic yeast, a chapter on the mathematical modelling of ion transport and two chapters on the role of transport in pathogenic yeasts and antifungal drug resistance. Each article provides both a general overview of the main transport characteristics of a specific substrate or group of substrates and the unique details that only an expert working in the field is able to transmit to the reader. Researchers and students of the topic will find this book to be a useful resource for membrane transport in yeast collecting information in one complete volume, which is otherwise scattered across many papers. This might also be interesting for scientists investigating other species in order to compare transport mechanisms with known functions in yeast with the cells on which they work.

Modern Phytomedicine

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Publisher : John Wiley & Sons
ISBN 13 : 3527609539
Total Pages : 404 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Modern Phytomedicine by : Iqbal Ahmad

Download or read book Modern Phytomedicine written by Iqbal Ahmad and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.

The Healing Forest

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Author :
Publisher : Timber Press (OR)
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Healing Forest by : Richard Evans Schultes

Download or read book The Healing Forest written by Richard Evans Schultes and published by Timber Press (OR). This book was released on 1990 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1516 species and variants are ethnopharmacologically described

Plant-derived Natural Products

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Publisher : Springer Science & Business Media
ISBN 13 : 0387854983
Total Pages : 588 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Plant-derived Natural Products by : Anne E. Osbourn

Download or read book Plant-derived Natural Products written by Anne E. Osbourn and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Bioactive Compounds from Plants

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Publisher : John Wiley & Sons
ISBN 13 : 0470514019
Total Pages : 254 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Bioactive Compounds from Plants by : Derek J. Chadwick

Download or read book Bioactive Compounds from Plants written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors. The isolation and characterization of plant products, the identification of their role in the plant, and ways of synthesizing identical compounds or more potent analogues are covered. Also includes methods of culturing plant tissues and genetic engineering as a means of increasing the yield of desired substances from plants. Special emphasis is placed on plants previously unknown to Western scientists.

Combating Fungal Infections

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Publisher : Springer Science & Business Media
ISBN 13 : 364212173X
Total Pages : 549 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Combating Fungal Infections by : Iqbal Ahmad

Download or read book Combating Fungal Infections written by Iqbal Ahmad and published by Springer Science & Business Media. This book was released on 2010-08-03 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.

Industrial Biotechnology

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110563339
Total Pages : 234 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Industrial Biotechnology by : Mukesh Yadav

Download or read book Industrial Biotechnology written by Mukesh Yadav and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-10-08 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Industrial Biotechnology summarizes different aspects of plant biotechnology such as using plants as sustainable resources, phytomedical applications, phytoremedation and genetic engineering of plant systems. These topics are discussed from an academic as well industrial perspective and thus highlight recent developments but also practical aspects of modern biotechnology.

Natural Products in Clinical Trials

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Publisher : Bentham Science Publishers
ISBN 13 : 1681082136
Total Pages : 253 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Natural Products in Clinical Trials by : Atta-ur- Rahman

Download or read book Natural Products in Clinical Trials written by Atta-ur- Rahman and published by Bentham Science Publishers. This book was released on 2018-03-03 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume brings reviews contributed by eminent scientists in the field. The first volume covers the following topics: - bioactive compounds from marine invertebrates - natural product derived drugs for immunological and inflammatory diseases - clinical trials of curcumin, camptothecin, astaxanthin, and biochanin - antibacterial and antifungal drugs from natural sources - natural products as anti-HIV medicines.

Nanocellulose and Nanohydrogel Matrices

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527341722
Total Pages : 382 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanocellulose and Nanohydrogel Matrices by : Mohammad Jawaid

Download or read book Nanocellulose and Nanohydrogel Matrices written by Mohammad Jawaid and published by John Wiley & Sons. This book was released on 2017-10-23 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book on nanocellulose and nanohydrogels for biomedical applications is unique in discussing recent advancements in the field, resulting in a comprehensive, well-structured overview of nanocellulose and nanohydrogel materials based nanocomposites. The book covers different types of nanocellulose materials and their recent developments in the drug delivery and nanomedicine sector, along with synthesis, characterization, as well as applications in the biotechnological and biomedical fields. The book also covers the current status and future perspectives of bacterial cellulose and polyester hydrogel matrices, their preparation, characterization, and tissue engineering applications of water soluble hydrogel matrices obtained from biodegradable sources. In addition, the chitosan-based hydrogel and nanogel matrices, their involvement in the current biofabrication technologies, and influencing factors towards the biomedical sector of biosensors, biopharmaceuticals, tissue engineering appliances, implant materials, diagnostic probes and surgical aids are very well documented. Further, the history of cellulose-based and conducting polymer-based nanohydrogels, their classification, synthesis methods and applicability to different sectors, the challenges associated with their use, recent advances on the inhibitors of apoptosis proteins are also included. The recent developments and applications in the drug delivery sector gives an overview of facts about the nanofibrillated cellulose and copoly(amino acid) hydrogel matrices in the biotechnology and biomedicine field. This book serves as an essential reference for researchers and academics in chemistry, pharmacy, microbiology, materials science and biomedical engineering.