Rational Therapeutics For Infants And Children

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Rational Therapeutics for Infants and Children

Author : Roundtable on Research and Development of Drugs Biologics and Medical Devices
Publisher :
ISBN 13 : 9780309382700
Total Pages : 136 pages
Book Rating : 4.3/5 (827 download)

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Book Synopsis Rational Therapeutics for Infants and Children by : Roundtable on Research and Development of Drugs Biologics and Medical Devices

Download or read book Rational Therapeutics for Infants and Children written by Roundtable on Research and Development of Drugs Biologics and Medical Devices and published by . This book was released on 2000-04-07 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.

Rational Therapeutics for Infants and Children

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309069378
Total Pages : 135 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Rational Therapeutics for Infants and Children by : Institute of Medicine

Download or read book Rational Therapeutics for Infants and Children written by Institute of Medicine and published by National Academies Press. This book was released on 2000-05-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.

Neonatal and Pediatric Pharmacology

Author : Sumner J. Yaffe
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781795389
Total Pages : 1072 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Neonatal and Pediatric Pharmacology by : Sumner J. Yaffe

Download or read book Neonatal and Pediatric Pharmacology written by Sumner J. Yaffe and published by Lippincott Williams & Wilkins. This book was released on 2011 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Neonatal and Pediatric Pharmacology offers guidelines for safe, effective, and rational drug therapy in newborns, children and adolescents. The book provides relevant and useful data on the molecular, physiologic, biochemical, and pharmacologic mechanisms of drug action and therapy in this population. The authors identify areas of innovative basic and translational research necessary for the continuing evaluation and development of drugs for the fetus, newborns, children and adolescents. Neonatal and Pediatric Pharmacology is is a valuable reference for all health care professionals who treat the fetus, newborns, children, and adolescents, including neonatologists, nurses, pediatricians, general practitioners, students, obstetricians, perinatologists, surgeons and allied health professionals. It will be useful anytime during the day and especially in the middle of the night when knowledge of appropriate indications, safe and effective use, dosage, and therapeutic regimen for a certain drug or molecular entity is immediately needed. The book is also directed to those involved in basic, clinical, and other academic pharmacological research, the pharmaceutical industry, and regulatory agencies dealing with drug and therapeutic developments for this population. Those teaching pharmacology and therapeutics will find this compilation of information extremely useful in preparing teaching materials"--Provided by publisher.

Rational Therapeutics for Infants and Children

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309183642
Total Pages : 135 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Rational Therapeutics for Infants and Children by : Institute of Medicine

Download or read book Rational Therapeutics for Infants and Children written by Institute of Medicine and published by National Academies Press. This book was released on 2000-04-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.

Yaffe and Aranda's Neonatal and Pediatric Pharmacology

Author : Jacob V. Aranda
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975112490
Total Pages : 2499 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Yaffe and Aranda's Neonatal and Pediatric Pharmacology by : Jacob V. Aranda

Download or read book Yaffe and Aranda's Neonatal and Pediatric Pharmacology written by Jacob V. Aranda and published by Lippincott Williams & Wilkins. This book was released on 2020-11-05 with total page 2499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.

Neonatal and Pediatric Pharmacology

Author : Sumner J. Yaffe
Publisher : Lippincott Raven
ISBN 13 : 9780781741859
Total Pages : 938 pages
Book Rating : 4.7/5 (418 download)

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Book Synopsis Neonatal and Pediatric Pharmacology by : Sumner J. Yaffe

Download or read book Neonatal and Pediatric Pharmacology written by Sumner J. Yaffe and published by Lippincott Raven. This book was released on 2005 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts at the forefront of current research and clinical practice, this volume provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. Coverage includes specific recommendations for all major drug classes and diseases, a detailed section on drugs and the newborn, and chapters on specific treatment settings such as the pediatric intensive care unit and emergency room. Also included are chapters on adverse effects and interactions and state-of-the-art discussions on pharmacokinetics, pharmacodynamics, pharmacogenetics, drug development, and clinical drug trials in infants and children. Appendices include a neonatal formulary and a pediatric formulary.

The Learning Healthcare System

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309133939
Total Pages : 374 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Learning Healthcare System by : Institute of Medicine

Download or read book The Learning Healthcare System written by Institute of Medicine and published by National Academies Press. This book was released on 2007-06-01 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: As our nation enters a new era of medical science that offers the real prospect of personalized health care, we will be confronted by an increasingly complex array of health care options and decisions. The Learning Healthcare System considers how health care is structured to develop and to apply evidence-from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement-and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers. The Learning Healthcare System is the first in a series that will focus on issues important to improving the development and application of evidence in health care decision making. The Roundtable on Evidence-Based Medicine serves as a neutral venue for cooperative work among key stakeholders on several dimensions: to help transform the availability and use of the best evidence for the collaborative health care choices of each patient and provider; to drive the process of discovery as a natural outgrowth of patient care; and, ultimately, to ensure innovation, quality, safety, and value in health care.

Drug Therapy in Infants

Author : Robert J. Roberts
Publisher : W.B. Saunders Company
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Drug Therapy in Infants by : Robert J. Roberts

Download or read book Drug Therapy in Infants written by Robert J. Roberts and published by W.B. Saunders Company. This book was released on 1984 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Just Babies

Author : Paul Bloom
Publisher : Crown
ISBN 13 : 0307886867
Total Pages : 230 pages
Book Rating : 4.3/5 (78 download)

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Book Synopsis Just Babies by : Paul Bloom

Download or read book Just Babies written by Paul Bloom and published by Crown. This book was released on 2013-11-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading cognitive scientist argues that a deep sense of good and evil is bred in the bone. From John Locke to Sigmund Freud, philosophers and psychologists have long believed that we begin life as blank moral slates. Many of us take for granted that babies are born selfish and that it is the role of society—and especially parents—to transform them from little sociopaths into civilized beings. In Just Babies, Paul Bloom argues that humans are in fact hardwired with a sense of morality. Drawing on groundbreaking research at Yale, Bloom demonstrates that, even before they can speak or walk, babies judge the goodness and badness of others’ actions; feel empathy and compassion; act to soothe those in distress; and have a rudimentary sense of justice. Still, this innate morality is limited, sometimes tragically. We are naturally hostile to strangers, prone to parochialism and bigotry. Bringing together insights from psychology, behavioral economics, evolutionary biology, and philosophy, Bloom explores how we have come to surpass these limitations. Along the way, he examines the morality of chimpanzees, violent psychopaths, religious extremists, and Ivy League professors, and explores our often puzzling moral feelings about sex, politics, religion, and race. In his analysis of the morality of children and adults, Bloom rejects the fashionable view that our moral decisions are driven mainly by gut feelings and unconscious biases. Just as reason has driven our great scientific discoveries, he argues, it is reason and deliberation that makes possible our moral discoveries, such as the wrongness of slavery. Ultimately, it is through our imagination, our compassion, and our uniquely human capacity for rational thought that we can transcend the primitive sense of morality we were born with, becoming more than just babies. Paul Bloom has a gift for bringing abstract ideas to life, moving seamlessly from Darwin, Herodotus, and Adam Smith to The Princess Bride, Hannibal Lecter, and Louis C.K. Vivid, witty, and intellectually probing, Just Babies offers a radical new perspective on our moral lives.

Integrative Pediatrics

Author : Timothy Culbert
Publisher : Oxford University Press
ISBN 13 : 9780199718047
Total Pages : 720 pages
Book Rating : 4.7/5 (18 download)

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Book Synopsis Integrative Pediatrics by : Timothy Culbert

Download or read book Integrative Pediatrics written by Timothy Culbert and published by Oxford University Press. This book was released on 2010-04-10 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is ample evidence that children and adolescents in large numbers are actively using integrative (complementary and alternative) therapies. Various studies now indicate that over 50% of pediatricians surveyed would refer a patient for integrative therapy, and they would welcome more natural therapies for children provided they were safe and effective. However, there has been little training for pediatricians in this area. Integrative Pediatrics addresses these issues and provides guidelines for pediatricians, parents, and general audiences in a balanced, evidence-based manner. In this volume in the Weil Integrative Medicine Library series, the authors describe a rational and evidence-based approach to the integrative therapy of childhood disorders and well-child care, integrating the principles of alternative and complementary therapies into the principles and practice of conventional pediatrics. The authors examine what works and what doesn't and offer practical guidelines for physicians to incorporate integrative medicine into their practice and how to advise patients and their parents on reasonable and effective therapies. The text also covers areas of controversy and identifies areas of uncertainty where future research is needed. Chapters also cite the best available evidence for both safety and efficacy of all therapies discussed. The series editor is Andrew Weil, MD, Professor and Director of the Program of Integrative Medicine at the University of Arizon. Dr. Weil's program was the first academic program in the US and he is the major name in integrative medicine in the US, and well-known around the world. His program's stated goal is "to combine the best ideas and practices of conventional and alternative medicine into cost effective treatments without embracing alternative practices uncritically."

Pediatric Drug Development

Author : Andrew E. Mulberg
Publisher : John Wiley & Sons
ISBN 13 : 1118312058
Total Pages : 782 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Pediatric Drug Development by : Andrew E. Mulberg

Download or read book Pediatric Drug Development written by Andrew E. Mulberg and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions. Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the unique challenges in conducting effective drug research and development in pediatric populations. This new edition covers the legal and ethical issues of consent and assent, the additional legal and safety protections for children, and the appropriate methods of surveillance and assessment for children of varying ages and maturity, particularly for patient reported outcomes. It includes new developments in biomarkers and surrogate endpoints, developmental pharmacology and other novel aspects of global pediatric drug development. It also encompasses the new regulatory initiatives across EU, US and ROW designed to encourage improved access to safe and effective medicines for children globally. From an international team of expert contributors Pediatric Drug Development: Concepts and Applications is the practical guide to all aspects of the research and development of safe and effective medicines for children.

Child of Mine

Author : Ellyn Satter
Publisher : Bull Publishing Company
ISBN 13 : 1936693267
Total Pages : 688 pages
Book Rating : 4.9/5 (366 download)

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Book Synopsis Child of Mine by : Ellyn Satter

Download or read book Child of Mine written by Ellyn Satter and published by Bull Publishing Company. This book was released on 2012-08-01 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely considered the leading book involving nutrition and feeding infants and children, this revised edition offers practical advice that takes into account the most recent research into such topics as: emotional, cultural, and genetic aspects of eating; proper diet during pregnancy; breast-feeding versus; bottle-feeding; introducing solid food to an infant's diet; feeding the preschooler; and avoiding mealtime battles. An appendix looks at a wide range of disorders including allergies, asthma, and hyperactivity, and how to teach a child who is reluctant to eat. The author also discusses the benefits and drawbacks of giving young children vitamins.

Handbook Of Pediatric Drug Therapy And Immunization

Author : Suneja
Publisher : Elsevier India
ISBN 13 : 9788131216729
Total Pages : 508 pages
Book Rating : 4.2/5 (167 download)

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Book Synopsis Handbook Of Pediatric Drug Therapy And Immunization by : Suneja

Download or read book Handbook Of Pediatric Drug Therapy And Immunization written by Suneja and published by Elsevier India. This book was released on 2008 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides comprehensive, up-to-date information about current guidelines for drug therapy in important diseases and emergencies in children; rational antimicrobial therapy; immunization and immunoprophylaxis. Besides others, the important topics covered include Blood Component Therapy and Antidotes for Common Poisoning . Separate sections deal with Drugs , Vaccines, Immunoglobulins and Antitoxins their indications, dosage, mode of use, precautions and other information. About the Author : - RK Suneja, former Head, Department of Pediatrics and Medical Superintendent, Hindu Rao Hospital is one of the leading pediatricians based at New Delhi, India.

Pediatric Manual Medicine

Author : Jane E. Carreiro
Publisher : Elsevier Health Sciences
ISBN 13 : 0702042757
Total Pages : 380 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Pediatric Manual Medicine by : Jane E. Carreiro

Download or read book Pediatric Manual Medicine written by Jane E. Carreiro and published by Elsevier Health Sciences. This book was released on 2009-03 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whilst Carreiro s other title, An Osteopathic Approach to Children, covers the theory on pediatric medicine from an osteopathic perspective exploring conditions and diseases of childhood, and the rational for osteopathic treatment, this new book deals with the practical methods to treating children and infants with osteopathic techniques. She includes background on NMT for children and infants. The text refers to all areas including fascias, ligaments, muscles and bones covering all techniques with regard to osteopathic treatment, including techniques such as BLT, a ligamentous technique, counterstrain using muscles, myofascial trigger points, myofascial realease, myofascial unwinding, etc.Covers practical methods to treating children and infants with osteopatic techniques.Includes NMT for children and infants.Comprehensive, referring to all areas, including the fascia.Elaborately illustrated with many drawings and photographs.Includes dissections showing anatomical changes during growth.Treatment covers different age groups.The perfect companion to Carreiro's first book: An Osteopathic Approach to Children.

Neonatal and Pediatric Pharmacology

Author : Sumner J. Yaffe
Publisher : Lww
ISBN 13 : 9781469875484
Total Pages : 1066 pages
Book Rating : 4.8/5 (754 download)

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Book Synopsis Neonatal and Pediatric Pharmacology by : Sumner J. Yaffe

Download or read book Neonatal and Pediatric Pharmacology written by Sumner J. Yaffe and published by Lww. This book was released on 2015-04-24 with total page 1066 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts at the forefront of current research and clinical practice, this volume provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. Includes updated information on drug interactions and regulatory issues.

Transforming the Workforce for Children Birth Through Age 8

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309324882
Total Pages : 706 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Transforming the Workforce for Children Birth Through Age 8 by : National Research Council

Download or read book Transforming the Workforce for Children Birth Through Age 8 written by National Research Council and published by National Academies Press. This book was released on 2015-07-23 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.

Ethical Conduct of Clinical Research Involving Children

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309133386
Total Pages : 445 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Ethical Conduct of Clinical Research Involving Children by : Institute of Medicine

Download or read book Ethical Conduct of Clinical Research Involving Children written by Institute of Medicine and published by National Academies Press. This book was released on 2004-07-09 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular.