Radiobiological Modelling In Radiation Oncology

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Radiobiological Modelling in Radiation Oncology

Author : Roger G. Dale
Publisher : British Inst of Radiology
ISBN 13 : 090574960X
Total Pages : 304 pages
Book Rating : 4.9/5 (57 download)

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Book Synopsis Radiobiological Modelling in Radiation Oncology by : Roger G. Dale

Download or read book Radiobiological Modelling in Radiation Oncology written by Roger G. Dale and published by British Inst of Radiology. This book was released on 2007 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The move towards individually-optimised treatments, using knowledge of normal tissue and tumour radiosensitivity, proliferation rates, etc, in combination with three-dimensional planning, will need mathematical modelling to achieve its full potential. This modelling process will also be capable of helping develop a rational and cost-effective use of resources.Amongst radiation oncologists and medical physicists there is a need for a greater understanding of the scope, applications and limitations of radiobiological modelling, particularly in complex situations that include multiple treatment variables, the respective influence of which are difficult to separate out by randomised trials without using radiobiologically-based analysis.In future there will be increasing use of modelling in practical situations, including treatment gap corrections, normal tissue tolerance predictions, optimisation of therapy determined by predictive assays, multi-modality schedule design, the simulation of clinical trials, testing contemporaneous medico-legal problems and teaching general principals of radiotherapy.

Radiotherapy Treatment Planning

Author : J. Donald Chapman
Publisher : CRC Press
ISBN 13 : 1439862605
Total Pages : 180 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Radiotherapy Treatment Planning by : J. Donald Chapman

Download or read book Radiotherapy Treatment Planning written by J. Donald Chapman and published by CRC Press. This book was released on 2016-04-21 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand Quantitative Radiobiology from a Radiation Biophysics PerspectiveIn the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and of

New Technologies in Radiation Oncology

Author : Wolfgang C. Schlegel
Publisher : Springer Science & Business Media
ISBN 13 : 3540299998
Total Pages : 453 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis New Technologies in Radiation Oncology by : Wolfgang C. Schlegel

Download or read book New Technologies in Radiation Oncology written by Wolfgang C. Schlegel and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Summarizes the state of the art in the most relevant areas of medical physics and engineering applied to radiation oncology - Covers all relevant areas of the subject in detail, including 3D imaging and image processing, 3D treatment planning, modern treatment techniques, patient positioning, and aspects of verification and quality assurance - Conveys information in a readily understandable way that will appeal to professionals and students with a medical background as well as to newcomers to radiation oncology from the field of physics

Radiobiology Self-Assessment Guide

Author : Jennifer Yu, MD, PhD
Publisher : Springer Publishing Company
ISBN 13 : 1617052914
Total Pages : 520 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Radiobiology Self-Assessment Guide by : Jennifer Yu, MD, PhD

Download or read book Radiobiology Self-Assessment Guide written by Jennifer Yu, MD, PhD and published by Springer Publishing Company. This book was released on 2016-11-03 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

Basic Clinical Radiobiology Fourth Edition

Author : Michael C. Joiner
Publisher : CRC Press
ISBN 13 : 0340929669
Total Pages : 392 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis Basic Clinical Radiobiology Fourth Edition by : Michael C. Joiner

Download or read book Basic Clinical Radiobiology Fourth Edition written by Michael C. Joiner and published by CRC Press. This book was released on 2009-03-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.

Basic Clinical Radiobiology

Author : Michael C. Joiner
Publisher : CRC Press
ISBN 13 : 0429955405
Total Pages : 361 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Basic Clinical Radiobiology by : Michael C. Joiner

Download or read book Basic Clinical Radiobiology written by Michael C. Joiner and published by CRC Press. This book was released on 2018-08-28 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Builds on success and reputation of previous editions Draws on the considerable teaching experience of an international author team, most notably the US and European Editors The gold-standard European text for training, adopted by ESTRO as a course book, as a text for the Royal College of Radiologists' radiobiology exam and by courses in the US Highly illustrated with new, 2 colour illustrations Clear and concise style, appropriate for trainees and also practising radiation oncologists requiring a ready reference to the subject Includes new chapters on stem cells, tissue response and the meeting point of meeting point of radiotherapy, radiobiology and physics

Big Data in Radiation Oncology

Author : Jun Deng
Publisher : CRC Press
ISBN 13 : 1351801112
Total Pages : 355 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Big Data in Radiation Oncology by : Jun Deng

Download or read book Big Data in Radiation Oncology written by Jun Deng and published by CRC Press. This book was released on 2019-03-07 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data in Radiation Oncology gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. While basic principles and key analytical and processing techniques are introduced in the early chapters, the rest of the book turns to clinical applications, in particular for cancer registries, informatics, radiomics, radiogenomics, patient safety and quality of care, patient-reported outcomes, comparative effectiveness, treatment planning, and clinical decision-making. More features of the book are: Offers the first focused treatment of the role of big data in the clinic and its impact on radiation therapy. Covers applications in cancer registry, radiomics, patient safety, quality of care, treatment planning, decision making, and other key areas. Discusses the fundamental principles and techniques for processing and analysis of big data. Address the use of big data in cancer prevention, detection, prognosis, and management. Provides practical guidance on implementation for clinicians and other stakeholders. Dr. Jun Deng is a professor at the Department of Therapeutic Radiology of Yale University School of Medicine and an ABR board certified medical physicist at Yale-New Haven Hospital. He has received numerous honors and awards such as Fellow of Institute of Physics in 2004, AAPM Medical Physics Travel Grant in 2008, ASTRO IGRT Symposium Travel Grant in 2009, AAPM-IPEM Medical Physics Travel Grant in 2011, and Fellow of AAPM in 2013. Lei Xing, Ph.D., is the Jacob Haimson Professor of Medical Physics and Director of Medical Physics Division of Radiation Oncology Department at Stanford University. His research has been focused on inverse treatment planning, tomographic image reconstruction, CT, optical and PET imaging instrumentations, image guided interventions, nanomedicine, and applications of molecular imaging in radiation oncology. Dr. Xing is on the editorial boards of a number of journals in radiation physics and medical imaging, and is recipient of numerous awards, including the American Cancer Society Research Scholar Award, The Whitaker Foundation Grant Award, and a Max Planck Institute Fellowship.

Radiobiology for the Radiologist

Author : Eric J. Hall
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781741514
Total Pages : 572 pages
Book Rating : 4.7/5 (415 download)

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Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall

Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review. The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.

Modelling Radiotherapy Side Effects

Author : TIZIANA. FIORINO RANCATI (CLAUDIO.)
Publisher : CRC Press
ISBN 13 : 9780367779719
Total Pages : 494 pages
Book Rating : 4.7/5 (797 download)

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Book Synopsis Modelling Radiotherapy Side Effects by : TIZIANA. FIORINO RANCATI (CLAUDIO.)

Download or read book Modelling Radiotherapy Side Effects written by TIZIANA. FIORINO RANCATI (CLAUDIO.) and published by CRC Press. This book was released on 2021-03-31 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an invaluable tutorial for radiation oncologists, medical physicists, and dosimetrists involved in the planning optimization phase of treatment. It presents a practical, accessible, and comprehensive summary of the field's current research and knowledge regarding the response of normal tissues to radiation.

Practical Radiobiology for Proton Therapy Planning

Author : Bleddyn Jones
Publisher :
ISBN 13 : 9780750313391
Total Pages : 242 pages
Book Rating : 4.3/5 (133 download)

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Book Synopsis Practical Radiobiology for Proton Therapy Planning by : Bleddyn Jones

Download or read book Practical Radiobiology for Proton Therapy Planning written by Bleddyn Jones and published by . This book was released on 2018-01-24 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Radiobiology for Proton Therapy Planning covers the principles, advantages and potential pitfalls that occur in proton therapy, especially its radiobiological modelling applications. This book is intended to educate, inform and to stimulate further research questions. Additionally, it will help proton therapy centres when designing new treatments or when unintended errors or delays occur. The clear descriptions of useful equations for high LET particle beam applications, worked examples of many important clinical situations, and discussion of how proton therapy may be optimized are all important features of the text. This important book blends the relevant physics, biology and medical aspects of this multidisciplinary subject.

Machine Learning With Radiation Oncology Big Data

Author : Jun Deng
Publisher : Frontiers Media SA
ISBN 13 : 2889457303
Total Pages : 146 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Machine Learning With Radiation Oncology Big Data by : Jun Deng

Download or read book Machine Learning With Radiation Oncology Big Data written by Jun Deng and published by Frontiers Media SA. This book was released on 2019-01-21 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Topics in Clinical Radiobiology of Tumors

Author : Hans-Peter Beck-Bornholdt
Publisher : Springer Science & Business Media
ISBN 13 : 3642849180
Total Pages : 364 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Current Topics in Clinical Radiobiology of Tumors by : Hans-Peter Beck-Bornholdt

Download or read book Current Topics in Clinical Radiobiology of Tumors written by Hans-Peter Beck-Bornholdt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of basic science radiobiological research is now being recognized of significant importance in clinical radiation oncology. Observations made in the laboratory using animals as'well as tissue culture have led to a better biologic understanding of techniques for altered fractionation, techniques for measuring tumor cell proliferation, the possi bilities and limitations of methods for evaluation of nonrandomized clinical studies in deriving time dose relationships for human tumors as well as a better understanding of repair kinetics in mammalian cells, fractionation sensitivity and the major impact oftechnologies to improve local/regional control with the subsequent impact on survival. These findings have led to changes in treatment schedules and have led to further close cooperation among the radiation oncologists and radiation biologists. Well support research efforts in radiation biology have a major and significant impact on the clinical care of the cancer patient. Studies that originated in the laboratory are now finding their way into clinical practice resulting in better local and regional control and improved number of patients surviving without disease.

Evolution of Ionizing Radiation Research

Author : Mitsuru Nenoi
Publisher : BoD – Books on Demand
ISBN 13 : 9535121677
Total Pages : 318 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Evolution of Ionizing Radiation Research by : Mitsuru Nenoi

Download or read book Evolution of Ionizing Radiation Research written by Mitsuru Nenoi and published by BoD – Books on Demand. This book was released on 2015-09-17 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The industrial and medical applications of radiation have been augmented and scientific insight into mechanisms for radiation action notably progressed. In addition, the public concern about radiation risk has also grown extensively. Today the importance of risk communication among stakeholders involved in radiation-related issues is emphasized much more than any time in the past. Thus, the circumstances of radiation research have drastically changed, and the demand for a novel approach to radiation-related issues is increasing. It is thought that the publication of the book Evolution of Ionizing Radiation Research at this time would have enormous impacts on the society. The editor believes that technical experts would find a variety of new ideas and hints in this book that would be helpful to them to tackle ionizing radiation.

Radiobiology of Glioblastoma

Author : Luigi Pirtoli
Publisher : Springer
ISBN 13 : 3319283057
Total Pages : 314 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Radiobiology of Glioblastoma by : Luigi Pirtoli

Download or read book Radiobiology of Glioblastoma written by Luigi Pirtoli and published by Springer. This book was released on 2016-06-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and ontologic models. Radiobiology of Glioblastoma: Recent Advances and Related Pathobiology will be of great value to pathologists, medical oncologists, radiation oncologists as well as basic researchers and clinical investigators.

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer

Author : Loredana G. Marcu
Publisher : CRC Press
ISBN 13 : 135100199X
Total Pages : 220 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Radiotherapy and Clinical Radiobiology of Head and Neck Cancer by : Loredana G. Marcu

Download or read book Radiotherapy and Clinical Radiobiology of Head and Neck Cancer written by Loredana G. Marcu and published by CRC Press. This book was released on 2018-05-15 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. Features: Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics Applies content by relating all radiobiological characteristics to their respective clinical implications Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

Handbook of Radiobiology

Author : Thayalan Kuppusamy
Publisher : JP Medical Ltd
ISBN 13 : 9386107430
Total Pages : 1 pages
Book Rating : 4.3/5 (861 download)

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Book Synopsis Handbook of Radiobiology by : Thayalan Kuppusamy

Download or read book Handbook of Radiobiology written by Thayalan Kuppusamy and published by JP Medical Ltd. This book was released on 2016-11-30 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiobiology, also known as radiation biology, is a field of clinical and basic medical sciences that involves the study of the action of ionising radiation on living things. This handbook is a complete guide to radiobiology for postgraduate students. Beginning with an overview of human biology and radiation physics, the following chapters explain the interaction of radiation with cells, its beneficial damage to cancer cells, and adverse effects on normal cells and organs. The final sections of the book cover time, dose and fractionation models, and radiation safety and protection. Enhanced by images and tables, this useful reference text is presented in a logical format with simple terms to assist learning and understanding. Key Points Complete guide to radiobiology for postgraduate students Covers beneficial damage to cancer cells and adverse effects on normal cells Explains time, dose and fractionation models Logical, easy to understand format

The Scientific Basis of Modern Radiotherapy

Author : Nicolas J. McNally
Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Scientific Basis of Modern Radiotherapy by : Nicolas J. McNally

Download or read book The Scientific Basis of Modern Radiotherapy written by Nicolas J. McNally and published by . This book was released on 1989 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews key areas of radiotherapy, examining the scientific basis in relation to clinical practice. It represents the proceedings of a conference held to mark the achievements of John Fowler and includes contributions from leading figures from Europe and the USA.