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Book Synopsis Rab GTPases and Membrane Trafficking by : Guangpu Li
Download or read book Rab GTPases and Membrane Trafficking written by Guangpu Li and published by Bentham Science Publishers. This book was released on 2012-05-21 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. Since their discovery over two decades ago, a wealth of information has accumulated about the roles that"
Download or read book Rab written by John Brown and published by . This book was released on 1880 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rab and His Friends written by John Brown and published by . This book was released on 1862 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rab, and Marjorie Fleming by : John Brown
Download or read book Rab, and Marjorie Fleming written by John Brown and published by . This book was released on 1882 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rab and His Friends and Other Papers by : John Brown
Download or read book Rab and His Friends and Other Papers written by John Brown and published by BoD – Books on Demand. This book was released on 2020-08-03 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproduction of the original: Rab and His Friends and Other Papers by John Brown
Download or read book Rab Butler written by Michael Jago and published by Biteback Publishing. This book was released on 2015-10-20 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite his tenure of three of the four Great Offices of State, his popularity with the electorate and the truly revolutionary 1944 Education Act that bears his name, Richard Austen ‘Rab’ Butler narrowly missed out on the premiership on three separate occasions during his political career, earning him the sobriquet that has attached to his name ever since - The Best Prime Minister That Britain Never Had. Banished from the inner council of the War Cabinet for his support of appeasement, Butler used his time as Education Minister wisely to emerge as the progressive face of the post-war Tory Party, going on to spend four years at the Treasury before the gradual but relentless eclipse of his career after Anthony Eden’s accession. Was Butler an over-ambitious, condescending intellectual who had antagonised enough colleagues in the course of his career to ensure he would ultimately be thwarted? Or did he simply not want the leadership enough? Could this liberal Tory, in tune with the electorate, have led the Conservatives to victory in the 1964 election? In this robust and insightful biography of the great nearly-man of British politics, bestselling author Michael Jago looks to answer whether Rab Butler really was ‘The Best Prime Minister We Never Had’.
Book Synopsis Rab GTPase-activating Proteins at the Golgi:endosome Interface by : Ryan Michael Nottingham
Download or read book Rab GTPase-activating Proteins at the Golgi:endosome Interface written by Ryan Michael Nottingham and published by Stanford University. This book was released on 2010 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rab GTPases are master regulators of membrane trafficking in eukaryotic cells. With GTP bound, they regulate trafficking by recruiting effectors to specific membrane-bound compartments. GTPase-activating proteins (GAPs) stimulate a Rab's intrinsic rate of GTP hydrolysis, thus inactivating the Rab by converting bound GTP to GDP. Regulation of Rab proteins links the formation and breakdown of sequential, Rab-regulated membrane domains in the secretory and endocytic pathways. This thesis presents the characterization of a novel RabGAP, RUTBC1. RUTBC1 binds Rab9 in vitro and in cells through interactions with its N-terminus. Overexpression of RUTBC1 only slightly disrupts MPR trafficking and RUTBC1 does not function as a GAP for Rab9. In vitro biochemical screening of Rab proteins revealed that RUTBC1 has GAP activity toward Rab33b and Rab32. These data suggest that RUTBC1 might function to link inactivation of these Rabs in relation to a Rab9 microdomain, in support of the existence of a Rab cascade at the interface between the Golgi apparatus and endosomes. Depletion of RUTBC1 unexpectedly led to concomitant depletion of Atg16L1. Atg16L1 has an established and essential role in macroautophagy, a highly conserved cellular recycling process. Overexpression of Atg16L1 caused the formation of large puncta in the cytoplasm, which are also labeled by endogenous RUTBC1 and may represent autophagosomes. Atg16L1 is a known Rab33b effector, suggesting that Rab33b, RUTBC1 and Atg16L1 function together to regulate autophagosome formation. Finally, RUTBC2, which is highly related to RUTBC1, also binds specifically to Rab9. In vitro biochemical screening for RUTBC2's Rab substrates showed that RUTBC2 had highest GAP activity toward Rab34 and Rab36, two very similar Rabs thought to play a role in secretion. The difference in substrate specificity between RUTBC1 and RUTBC2 further exemplifies the highly complex integration of diverse membrane trafficking pathways in mammalian cells.
Book Synopsis RAB: The Life of R.A. Butler by : Anthony Howard
Download or read book RAB: The Life of R.A. Butler written by Anthony Howard and published by A&C Black. This book was released on 2013-02-07 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richard Austin Butler remains the great enigma of post-war British politics. Independent, indiscreet and never anything but irreverent, Butler commanded the respect of both sides of the Commons and would have been, on several occasions, the people's choice for premier. From his entry into politics in 1929 to his retirement from that arena in 1965, Butler's story is also that of British political life through almost four decades. Scarred by his association with the appeasers of Munich, he won the respect of the nation as the architect of the 1944 Education Act. From the viewpoint of these times of Tory wets and dries, Butler appears the victim of the age that divided gentlemen from players. In these pages, one of our most distinguished political journalists offers a revealing portrait of 'the best Prime Minister we never had'.
Book Synopsis Role-Modeling Socialist Behavior: The Life and Letters of Isaac Rab by : Karla Doris Rab
Download or read book Role-Modeling Socialist Behavior: The Life and Letters of Isaac Rab written by Karla Doris Rab and published by Lulu.com. This book was released on 2010-08-02 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isaac Rab (1893 - 1986) was a well-known agitator for Socialism in the Boston area, as a soap-box orator, a lecturer and a teacher, for most of the Twentieth Century. He was among the founding members of the World Socialist Party and organized a Boston Local in 1932, in which he was a central figure for many years. Today the WSP(US) remains a companion party of the World Socialist Movement.
Book Synopsis Rab and his friends and other papers by : John Brown
Download or read book Rab and his friends and other papers written by John Brown and published by . This book was released on 1861 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rab and his Friends by : John BROWN (M.D., of Edinburgh.)
Download or read book Rab and his Friends written by John BROWN (M.D., of Edinburgh.) and published by . This book was released on 1863 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Spare Hours: Rab and his friends and other papers by : John Brown
Download or read book Spare Hours: Rab and his friends and other papers written by John Brown and published by . This book was released on 1862 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Horae subsecivae. Rab and His Friends, and Other Papers by : John Brown
Download or read book Horae subsecivae. Rab and His Friends, and Other Papers written by John Brown and published by Good Press. This book was released on 2021-05-19 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Horae subsecivae. Rab and His Friends, and Other Papers" by John Brown. Published by Good Press. Good Press publishes a wide range of titles that encompasses every genre. From well-known classics & literary fiction and non-fiction to forgotten−or yet undiscovered gems−of world literature, we issue the books that need to be read. Each Good Press edition has been meticulously edited and formatted to boost readability for all e-readers and devices. Our goal is to produce eBooks that are user-friendly and accessible to everyone in a high-quality digital format.
Book Synopsis Rab and His Friends, and Marjorie Fleming. [With Illustrations.] by : John Brown
Download or read book Rab and His Friends, and Marjorie Fleming. [With Illustrations.] written by John Brown and published by . This book was released on 1876 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rab and his friends and other papers.-ser. 2 John Leech, Marjorie Fleming and other papers.-ser. 3 Locke and Sydenham and other papers by : John Brown
Download or read book Rab and his friends and other papers.-ser. 2 John Leech, Marjorie Fleming and other papers.-ser. 3 Locke and Sydenham and other papers written by John Brown and published by . This book was released on 1861 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rab & his friends, & other papers & essays. Repr by : John Brown
Download or read book Rab & his friends, & other papers & essays. Repr written by John Brown and published by . This book was released on 1907 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Horae Subsecivae: Rab and his friends, and other papers. 11th ed. 1882 by : John Brown
Download or read book Horae Subsecivae: Rab and his friends, and other papers. 11th ed. 1882 written by John Brown and published by . This book was released on 1882 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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