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Author : P. D. Sethi
Publisher :
ISBN 13 : 9788123905600
Total Pages : 692 pages
Book Rating : 4.9/5 (56 download)
Download or read book Quantitative Analysis of Drugs in Pharmaceutical Formulations, 3e written by P. D. Sethi and published by . This book was released on 2008-02-01 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Prabhu Dayal Sethi
Publisher :
ISBN 13 : 9788190000505
Total Pages : 478 pages
Book Rating : 4.0/5 (5 download)
Download or read book Quantitative Analysis of Drugs in Pharmaceutical Formulations written by Prabhu Dayal Sethi and published by . This book was released on 1985 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Donald Clarence. Garratt
Publisher : Springer Science & Business Media
ISBN 13 : 1461333806
Total Pages : 937 pages
Book Rating : 4.4/5 (613 download)
Download or read book The Quantitative Analysis of Drugs written by Donald Clarence. Garratt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 937 pages. Available in PDF, EPUB and Kindle. Book excerpt: General Monographs, Alphabetically Arranged and Consisting of Methods for Quantitative Determination of the Substance, its Salts, and Preparations of Which it is a Principal Con- Stituent.- Synthetic Organic Compounds, Methods for Determination of Substances not Included in the General Monographs.- Essential Oils.- Oils, Fats and Waxes.- Appendices.- I. Determination of Alcohol Content.- II. Complexometric Titrations.- III. Non-aqueous Titrations.- IV. The Oxygen-Flask Combustion Technique.- V. Determination of Water.- VI. Extraneous Matter in Food and Drugs.- VII. Microbiological Assays.- VII.
Author : Iwona Wawer
Publisher : Elsevier
ISBN 13 : 0080558194
Total Pages : 528 pages
Book Rating : 4.0/5 (85 download)
Download or read book NMR Spectroscopy in Pharmaceutical Analysis written by Iwona Wawer and published by Elsevier. This book was released on 2008-08-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership
Author : S. Görög
Publisher : Elsevier
ISBN 13 : 9780080534404
Total Pages : 772 pages
Book Rating : 4.5/5 (344 download)
Download or read book Identification and Determination of Impurities in Drugs written by S. Görög and published by Elsevier. This book was released on 2000-05-19 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis. Due to the very rapid development of the analytical methodologies available for this purpose and the similarly rapid increase of the demands as regards the purity of drugs it is an important task to give a summary of the problems and the various possibilities offered by modern analytical chemistry for their solution. That is the aim of this book. The book is methodology-oriented. In the first chapter some important aspects of the background of impurity-related analytical studies (toxicological, pharmacopoeial aspects, the characterisation of the sources of impurities and the role of impurity profiling in various fields of drug research, production and therapeutic use) are summarised. Chapter two deals with related organic impurities, the strategies for impurity profiling, the use of chromatographic and related separation methods, spectroscopic, and hyphenated techniques. The subject of the third chapter is the identification and determination of residual solvents. The determination of inorganic impurities is discussed in chapter four. The special problems of degradation products as impurities are dealt with in chapter five. A separate chapter has been compiled to deal with one of the most up-to-date problems in contemporary pharmaceutical analysis, the estimation of enantiomeric purity of chiral drugs. Chapter seven is devoted to various approaches to solve the problem of polymorphic modifications as impurities. Since in the broader sense of the word the microbiological purity of drugs and drug products also belongs to this circle, the most important information from this field is summarised in chapter eight. After the mainly methodology-oriented chapters, the final one concentrates on four groups of drugs (peptides, biotechnological products, antibiotics and steroids) in order to demonstrate the use of the methods described earlier.
Author : Olga V. Marchenko
Publisher : Springer Nature
ISBN 13 : 3030485552
Total Pages : 445 pages
Book Rating : 4.0/5 (34 download)
Download or read book Quantitative Methods in Pharmaceutical Research and Development written by Olga V. Marchenko and published by Springer Nature. This book was released on 2020-09-24 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
Author : Anette Müllertz
Publisher : Springer
ISBN 13 : 1493940295
Total Pages : 838 pages
Book Rating : 4.4/5 (939 download)
Download or read book Analytical Techniques in the Pharmaceutical Sciences written by Anette Müllertz and published by Springer. This book was released on 2016-08-30 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.
Author : Rajat Sethi
Publisher :
ISBN 13 : 9788123918693
Total Pages : 493 pages
Book Rating : 4.9/5 (186 download)
Download or read book Sethi's Hplc High Performance Liquid Chromatography: Quantitative Analysis Of Pharmaceutical Formulations, Vol. 3 (hb) written by Rajat Sethi and published by . This book was released on 2010-01-01 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P. D. Sethi
Publisher : CBS Publishers & Distributors Pvt Limited, India
ISBN 13 : 9788123921877
Total Pages : pages
Book Rating : 4.9/5 (218 download)
Download or read book Sethi's Quantitative Analysis of Pharmaceutical Formulations written by P. D. Sethi and published by CBS Publishers & Distributors Pvt Limited, India. This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9788123926568
Total Pages : pages
Book Rating : 4.9/5 (265 download)
Download or read book SETHIS HPLC HIGH PERF LIQ CHROM written by and published by . This book was released on 2015-01-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9788123926537
Total Pages : pages
Book Rating : 4.9/5 (265 download)
Download or read book SETHIS HPLC HIGH PERF LIQ CHROM written by and published by . This book was released on 2015-01-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9788123926544
Total Pages : pages
Book Rating : 4.9/5 (265 download)
Download or read book SETHIS HPLC HIGH PERF LIQ CHROM written by and published by . This book was released on 2015-01-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309269393
Total Pages : 377 pages
Book Rating : 4.3/5 (92 download)
Download or read book Countering the Problem of Falsified and Substandard Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adulteration and fraudulent manufacture of medicines is an old problem, vastly aggravated by modern manufacturing and trade. In the last decade, impotent antimicrobial drugs have compromised the treatment of many deadly diseases in poor countries. More recently, negligent production at a Massachusetts compounding pharmacy sickened hundreds of Americans. While the national drugs regulatory authority (hereafter, the regulatory authority) is responsible for the safety of a country's drug supply, no single country can entirely guarantee this today. The once common use of the term counterfeit to describe any drug that is not what it claims to be is at the heart of the argument. In a narrow, legal sense a counterfeit drug is one that infringes on a registered trademark. The lay meaning is much broader, including any drug made with intentional deceit. Some generic drug companies and civil society groups object to calling bad medicines counterfeit, seeing it as the deliberate conflation of public health and intellectual property concerns. Countering the Problem of Falsified and Substandard Drugs accepts the narrow meaning of counterfeit, and, because the nuances of trademark infringement must be dealt with by courts, case by case, the report does not discuss the problem of counterfeit medicines.
Author : Gus R. Rosania
Publisher : Humana
ISBN 13 : 9781071612491
Total Pages : 453 pages
Book Rating : 4.6/5 (124 download)
Download or read book Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery written by Gus R. Rosania and published by Humana. This book was released on 2021-07-12 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.
Author : Donald Clarence. Garratt
Publisher : Springer
ISBN 13 : 9780412148101
Total Pages : 926 pages
Book Rating : 4.1/5 (481 download)
Download or read book The Quantitative Analysis of Drugs written by Donald Clarence. Garratt and published by Springer. This book was released on 1976-09-09 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Satish Gabhe
Publisher : GRIN Verlag
ISBN 13 : 3656633231
Total Pages : 109 pages
Book Rating : 4.6/5 (566 download)
Download or read book Simultaneous Estimation of Some Drugs in Bulk and in their Formulation by Chromatographic Methods. written by Satish Gabhe and published by GRIN Verlag. This book was released on 2014-04-09 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, Pharmacy, , course: MASTER OF PHARMACY (Quality Assurance Techniques), language: English, abstract: A number of new drug entities, modifications of existing ones, and multi-component formulations are entering the market, every year. Development of simple analytical methods for analysis of various drugs in multi - component formulations is a tricky task for an analytical researcher. As analytical techniques are used throughout drug development, manufacturing, release of drug products, the reliability of their results is essential. Chromatographic methods are most useful and powerful techniques for qualitative and quantitative determination of drug/s. Therefore, appropriate validation to demonstrate the performance and suitability of the analytical method is much more than a formal requirement. Hence, there is need to develop and validate correct analytical method for these medicine/s. This book details, - Development and validation of HPTLC - densitometric method for concurrent estimation of metformin hydrochloride, pioglitazone hydrochloride and gliclazide in combined dosage form. - Development and validation of HPTLC method for simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in combined pharmaceutical dosage form. - Development and validation of RP - HPLC method for simultaneous estimation of ciprofloxacin hydrochloride and dexamethasone in combined dosage form, which is better alternative to existing one. The developed analytical methods are simple, selective, accurate, robust, and precise with shorter analysis time for the analysis of drug/s in combined pharmaceutical dosage forms. All the developed HPTLC and HPLC methods have been validated as per ICH Q2 (R1) guidelines. Developed analytical methods could boost analytical researcher to work more efficiently in the field of analytical method development and validation of Pharmaceutical dosage forms.
Author : Prabhu Dayal Sethi
Publisher :
ISBN 13 : 9788123907314
Total Pages : 895 pages
Book Rating : 4.9/5 (73 download)
Download or read book HPLC written by Prabhu Dayal Sethi and published by . This book was released on 2001 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt:
