Analytical Techniques In The Pharmaceutical Sciences

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Analytical Techniques in the Pharmaceutical Sciences

Author : Anette Müllertz
Publisher : Springer
ISBN 13 : 1493940295
Total Pages : 838 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Analytical Techniques in the Pharmaceutical Sciences by : Anette Müllertz

Download or read book Analytical Techniques in the Pharmaceutical Sciences written by Anette Müllertz and published by Springer. This book was released on 2016-08-30 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.

Introduction to Pharmaceutical Analytical Chemistry

Author : Stig Pedersen-Bjergaard
Publisher : John Wiley & Sons
ISBN 13 : 1119362725
Total Pages : 546 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Introduction to Pharmaceutical Analytical Chemistry by : Stig Pedersen-Bjergaard

Download or read book Introduction to Pharmaceutical Analytical Chemistry written by Stig Pedersen-Bjergaard and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die umfassend überarbeitete 2. Auflage enthält ein neues Kapitel zur chemischen Analyse von Biopharmazeutika, in dem die Identifizierung, Reinheitsprüfung und die Analyse on Peptiden und proteinbasierten Formulierungen erläutert werden. Die neue Auflage bietet ebenfalls verbesserte farbige Abbildungen und Tabellen, eine gestraffte Kapitelstruktur und überarbeitete Inhalte, die das Fachgebiet klarer und verständlicher präsentieren. - Bietet eine Einführung in die grundlegenden Konzepte der pharmazeutischen analytischen Chemie und Statistik. - Untersucht systematisch pharmazeutische Anwendungen, die in anderen Lehrbüchern zu dem Fachgebiet fehlen. - Untersucht verschiedene Analysetechniken, die in der Regel in Pharmalaboren zur Anwendung kommen. - Präsentiert Fragestellungen aus der Praxis, aktuelle praktische Beispiele und detaillierte Illustrationen. - Die aktualisierten Inhalte entsprechen den aktuellen europäischen und US-amerikanischen Arzneibuchvorschriften und -richtlinien.

Essentials of Pharmaceutical Analysis

Author : Muhammad Sajid Hamid Akash
Publisher : Springer Nature
ISBN 13 : 9811515476
Total Pages : 235 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Essentials of Pharmaceutical Analysis by : Muhammad Sajid Hamid Akash

Download or read book Essentials of Pharmaceutical Analysis written by Muhammad Sajid Hamid Akash and published by Springer Nature. This book was released on 2019-12-17 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.

Introduction to Pharmaceutical Chemical Analysis

Author : Steen Honoré Hansen
Publisher : John Wiley & Sons
ISBN 13 : 1119954339
Total Pages : 511 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Introduction to Pharmaceutical Chemical Analysis by : Steen Honoré Hansen

Download or read book Introduction to Pharmaceutical Chemical Analysis written by Steen Honoré Hansen and published by John Wiley & Sons. This book was released on 2011-10-18 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Analytical Techniques in Biosciences

Author : Chukwuebuka Egbuna
Publisher : Academic Press
ISBN 13 : 0128227990
Total Pages : 302 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Analytical Techniques in Biosciences by : Chukwuebuka Egbuna

Download or read book Analytical Techniques in Biosciences written by Chukwuebuka Egbuna and published by Academic Press. This book was released on 2021-10-21 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry. The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences. Presents basic analytical protocols and sample-preparation guidelines Details the various analytical techniques, including centrifugation, spectrometry, chromatography, and titrimetry Describes advanced techniques such as hyphenated techniques, electroanalytical techniques, and the application of biosensors in biomedical research Presents biostatistical tools and methods and basic computational models in biosciences

Introduction to Pharmaceutical Chemical Analysis

Author : Steen Hansen
Publisher : John Wiley & Sons
ISBN 13 : 0470661224
Total Pages : 511 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Introduction to Pharmaceutical Chemical Analysis by : Steen Hansen

Download or read book Introduction to Pharmaceutical Chemical Analysis written by Steen Hansen and published by John Wiley & Sons. This book was released on 2011-12-12 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Handbook of Pharmaceutical Analysis

Author : Lena Ohannesian
Publisher : CRC Press
ISBN 13 : 0824741943
Total Pages : 605 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Handbook of Pharmaceutical Analysis by : Lena Ohannesian

Download or read book Handbook of Pharmaceutical Analysis written by Lena Ohannesian and published by CRC Press. This book was released on 2001-11-09 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

Pharmaceutical Analysis E-Book

Author : David G. Watson
Publisher : Elsevier Health Sciences
ISBN 13 : 0702069884
Total Pages : 480 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Pharmaceutical Analysis E-Book by : David G. Watson

Download or read book Pharmaceutical Analysis E-Book written by David G. Watson and published by Elsevier Health Sciences. This book was released on 2015-12-24 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on Biotech products. New chapter on electrochemical methods in diagnostics. Greatly extended chapter on molecular emission spectroscopy to accommodate developments and innovations in the area. Now on StudentConsult

Handbook of Modern Pharmaceutical Analysis

Author : Satinder Ahuja
Publisher : Academic Press
ISBN 13 : 9780123759818
Total Pages : 598 pages
Book Rating : 4.7/5 (598 download)

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Book Synopsis Handbook of Modern Pharmaceutical Analysis by : Satinder Ahuja

Download or read book Handbook of Modern Pharmaceutical Analysis written by Satinder Ahuja and published by Academic Press. This book was released on 2010-11-11 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

Author : M.M.W.B. Hendriks
Publisher : Elsevier
ISBN 13 : 9780080540634
Total Pages : 345 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products by : M.M.W.B. Hendriks

Download or read book Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products written by M.M.W.B. Hendriks and published by Elsevier. This book was released on 1996-12-11 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given. Features of this book: • Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry • Illustrates the different approaches available to attain robustness • Gives ideas on how to use methods in practical situations. The book is intended for those who develop and optimize, and are responsible for the overall quality of, analytical methods and pharmaceutical technological products and procedures.

HPLC Methods for Pharmaceutical Analysis, Volumes 2-4

Author : George Lunn
Publisher : Wiley-Interscience
ISBN 13 : 9780471332961
Total Pages : 0 pages
Book Rating : 4.3/5 (329 download)

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Book Synopsis HPLC Methods for Pharmaceutical Analysis, Volumes 2-4 by : George Lunn

Download or read book HPLC Methods for Pharmaceutical Analysis, Volumes 2-4 written by George Lunn and published by Wiley-Interscience. This book was released on 2000-01-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most commonly used method for analyzing substances, and the first method most researchers turn to, is high performance liquid chromatography (HPLC). Following up on a best-seller, volumes 2-4 continue to provide an easily-accessible collection of procedures for analyzing pharmaceuticals using HPLC.

Validation of Analytical Methods for Pharmaceutical Analysis

Author : Oona McPolin
Publisher : Lulu.com
ISBN 13 : 0956152813
Total Pages : 154 pages
Book Rating : 4.9/5 (561 download)

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Book Synopsis Validation of Analytical Methods for Pharmaceutical Analysis by : Oona McPolin

Download or read book Validation of Analytical Methods for Pharmaceutical Analysis written by Oona McPolin and published by Lulu.com. This book was released on 2009-05-01 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive guide on validating analytical methods. Key features: Full review of the available regulatory guidelines on validation and in particular, ICH. Sections of the guideline, Q2(R1), have been reproduced in this book with the kind permission of the ICH Secretariat; Thorough discussion of each of the validation characteristics (Specificity; Linearity; Range; Accuracy; Precision; Detection Limit; Quantitation Limit; Robustness; System Suitability) plus practical tips on how they may be studied; What to include in a validation protocol with advice on the experimental procedure to follow and selection of appropriate acceptance criteria; How to interpret and calculate the results of a validation study including the use of suitable statistical calculations; A fully explained case study demonstrating how to plan a validation study, what to include in the protocol, experiments to perform, setting acceptance criteria, interpretation of the results and reporting the study.

Analytical Method Development and Validation

Author : Michael E. Swartz
Publisher : CRC Press
ISBN 13 : 1482229773
Total Pages : 95 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Analytical Method Development and Validation by : Michael E. Swartz

Download or read book Analytical Method Development and Validation written by Michael E. Swartz and published by CRC Press. This book was released on 2018-10-03 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.

Drug Stereochemistry

Author : Krzysztof Jozwiak
Publisher : CRC Press
ISBN 13 : 1420092391
Total Pages : 332 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Drug Stereochemistry by : Krzysztof Jozwiak

Download or read book Drug Stereochemistry written by Krzysztof Jozwiak and published by CRC Press. This book was released on 2012-04-23 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology. Topics include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery How stereochemistry impacts decisions made in the absorption, distribution, metabolism, excretion, and toxicity (ADMET) stages of drug discovery Pharmacokinetics and pharmacodynamics and the issues faced during the final stages of the drug development process The impact of the International Conference on Harmonisation (ICH) on the use of single isomer drugs Chiral switches The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs Patent issues surrounding chiral switches and the marketing of single enantiomer switches The book provides a solid background on stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. It is a one-stop reference for pharmaceutical scientists and chemists working with chiral drug molecules.

Handbook of Analytical Quality by Design

Author : Sarwar Beg
Publisher : Academic Press
ISBN 13 : 0128203331
Total Pages : 225 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Handbook of Analytical Quality by Design by : Sarwar Beg

Download or read book Handbook of Analytical Quality by Design written by Sarwar Beg and published by Academic Press. This book was released on 2021-01-09 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields. Concise language for easy understanding of the novel and holistic concept Covers key aspects of analytical development and validation Provides a robust, flexible, operable range for an analytical method with greater excellence and regulatory compliance

HPLC for Pharmaceutical Scientists

Author : Yuri V. Kazakevich
Publisher : John Wiley & Sons
ISBN 13 : 0470087943
Total Pages : 1136 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis HPLC for Pharmaceutical Scientists by : Yuri V. Kazakevich

Download or read book HPLC for Pharmaceutical Scientists written by Yuri V. Kazakevich and published by John Wiley & Sons. This book was released on 2007-02-16 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES

Author : Dr. Venkata Suresh Jilakara , Dr. Har Govind Garg, Mr. P. S. Minhas , Mrs. Bhanupriya Bhrigu , Dr. Anuja Chopra
Publisher : Shashwat Publication
ISBN 13 : 936087048X
Total Pages : 412 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES by : Dr. Venkata Suresh Jilakara , Dr. Har Govind Garg, Mr. P. S. Minhas , Mrs. Bhanupriya Bhrigu , Dr. Anuja Chopra

Download or read book MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES written by Dr. Venkata Suresh Jilakara , Dr. Har Govind Garg, Mr. P. S. Minhas , Mrs. Bhanupriya Bhrigu , Dr. Anuja Chopra and published by Shashwat Publication. This book was released on 2024-05-13 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the ever-evolving landscape of pharmaceutical sciences, the role of analytical techniques cannot be overstated. The quality, safety, and efficacy of pharmaceutical products hinge upon the precision and reliability of analytical methods employed throughout their development, manufacturing, and regulatory approval processes. The past few decades have witnessed remarkable strides in analytical instrumentation, methodologies, and data analysis, catalyzing a paradigm shift in pharmaceutical analytics. This book is conceived as a comprehensive guide to modern pharmaceutical analytical techniques, aiming to bridge the gap between theoretical knowledge and practical application in the dynamic pharmaceutical industry. It is designed to serve as an invaluable resource for students, researchers, and professionals engaged in pharmaceutical analysis, providing a systematic overview of the state-of-the-art analytical tools and strategies employed in drug discovery, development, and quality control. Each chapter is meticulously crafted to deliver comprehensive insights into the theoretical foundations, practical considerations, and recent advances pertinent to the respective analytical technique, supplemented with illustrative examples, case studies, and critical discussions. Moreover, special attention is devoted to emerging trends, such as nanotechnology-enabled analytical platforms, microfluidic-based assays, and in silico predictive modeling, underscoring the transformative potential of cutting-edge technologies in reshaping the landscape of pharmaceutical analytics. It is our fervent hope that this book will serve as a catalyst for fostering interdisciplinary collaboration, driving innovation, and advancing best practices in pharmaceutical analytical sciences. We extend our sincere gratitude to the contributors for their scholarly contributions and dedication, as well as to the readers for their interest and engagement in this endeavor.