Quantification of Biophysical Parameters in Medical Imaging

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Author :
Publisher : Springer
ISBN 13 : 3319659243
Total Pages : 497 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Quantification of Biophysical Parameters in Medical Imaging by : Ingolf Sack

Download or read book Quantification of Biophysical Parameters in Medical Imaging written by Ingolf Sack and published by Springer. This book was released on 2018-02-21 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a selection of essential knowledge on the image-based quantification of biophysical parameters for the purpose of clinical diagnosis. The authors regard clinical imaging scanners as physical measurement systems capable of quantifying intrinsic parameters for depiction of the constitution and biophysical properties of in vivo tissue. On the one hand, this approach supports the development of new methods of imaging highly reproducible, system-independent, and quantitative biomarkers, and these methods receive detailed attention in the book. On the other hand, the reader will also gain a deeper understanding of how physical tissue properties interact with the generation of signals in medical imaging, opening new windows on the intricate and fascinating relationship between the structure and function of living tissues. The book will be of interest to all who recognize the limitations of basing clinical diagnosis primarily on visual inspection of images and who wish to learn more about the diagnostic potential of quantitative and biophysics-based medical imaging markers and the challenges that the paucity of such markers poses for next-generation imaging technologies.

Quantitative Analysis in Nuclear Medicine Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 0387254447
Total Pages : 593 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Quantitative Analysis in Nuclear Medicine Imaging by : Habib Zaidi

Download or read book Quantitative Analysis in Nuclear Medicine Imaging written by Habib Zaidi and published by Springer Science & Business Media. This book was released on 2006-07-11 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.

Fast Quantitative Magnetic Resonance Imaging

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Author :
Publisher : Springer Nature
ISBN 13 : 303101667X
Total Pages : 124 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Fast Quantitative Magnetic Resonance Imaging by : Guido Buonincontri

Download or read book Fast Quantitative Magnetic Resonance Imaging written by Guido Buonincontri and published by Springer Nature. This book was released on 2022-05-31 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.

Quantification of Contrast Kinetics in Clinical Imaging

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Publisher : Springer
ISBN 13 : 3319646389
Total Pages : 184 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Quantification of Contrast Kinetics in Clinical Imaging by : Massimo Mischi

Download or read book Quantification of Contrast Kinetics in Clinical Imaging written by Massimo Mischi and published by Springer. This book was released on 2018-11-02 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive survey of the pharmacokinetic models used for the quantitative interpretation of contrast-enhanced imaging. It discusses all the available imaging technologies and the problems related to the calibration of the imaging system and accuracy of the estimated physiological parameters. Enhancing imaging modalities using contrast agents has opened up new opportunities for going beyond morphological information and enabling minimally invasive assessment of tissue and organ functionality down to the molecular level. In combination with mathematical modeling of the contrast agent kinetics, contrast- enhanced imaging has the potential to provide clinically valuable additional information by estimating quantitative physiological parameters. The book presents the broad spectrum of diagnostic possibilities provided by quantitative contrast-enhanced imaging, with a particular focus on cardiology and oncology, as well as novel developments in the area of quantitative molecular imaging along with their potential clinical applications. Given the variety of available techniques, the choice of the appropriate imaging modality and the most suitable pharmacokinetic model is often challenging. As such, the book provides a valuable technical guide for researchers, clinical scientists, and experts in the field who wish to better understand and properly apply tracer-kinetic modeling for quantitative contrast-enhanced imaging.

Fluorescence Imaging and Biological Quantification

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Publisher : CRC Press
ISBN 13 : 1351647334
Total Pages : 376 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Fluorescence Imaging and Biological Quantification by : Raquel Seruca

Download or read book Fluorescence Imaging and Biological Quantification written by Raquel Seruca and published by CRC Press. This book was released on 2017-09-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.

Quantifying Morphology and Physiology of the Human Body Using MRI

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Author :
Publisher : Taylor & Francis
ISBN 13 : 1439852685
Total Pages : 525 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Quantifying Morphology and Physiology of the Human Body Using MRI by : L. Tugan Muftuler

Download or read book Quantifying Morphology and Physiology of the Human Body Using MRI written by L. Tugan Muftuler and published by Taylor & Francis. This book was released on 2013-05-02 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introduce new frontiers of study into disease mechanisms.

Improving Assessments of Hemodynamics and Vascular Disease

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176850986
Total Pages : 64 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Improving Assessments of Hemodynamics and Vascular Disease by : Magnus Ziegler

Download or read book Improving Assessments of Hemodynamics and Vascular Disease written by Magnus Ziegler and published by Linköping University Electronic Press. This book was released on 2019-04-24 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood vessels are more than simple pipes, passively enabling blood to pass through them. Their form and function are dynamic, changing with both aging and disease. This process involves a feedback loop wherein changes to the shape of a blood vessel affect the hemodynamics, causing yet more structural adaptation. This feedback loop is driven in part by the hemodynamic forces generated by the blood flow, and the distribution and strength of these forces appear to play a role in the initiation, progression, severity, and the outcome of vascular diseases. Magnetic Resonance Imaging (MRI) offers a unique platform for investigating both the form and function of the vascular system. The form of the vascular system can be examined using MR-based angiography, to generate detailed geometric analyses, or through quantitative techniques for measuring the composition of the vessel wall and atherosclerotic plaques. To complement these analyses, 4D Flow MRI can be used to quantify the functional aspect of the vascular system, by generating a full time-resolved three-dimensional velocity field that represents the blood flow. This thesis aims to develop and evaluate new methods for assessing vascular disease using novel hemodynamic markers generated from 4D Flow MRI and quantitative MRI data towards the larger goal of a more comprehensive non-invasive examination oriented towards vascular disease. In Paper I, we developed and evaluated techniques to quantify flow stasis in abdominal aortic aneurysms to measure this under-explored aspect of aneurysmal hemodynamics. In Paper II, the distribution and intensity of turbulence in the aorta was quantified in both younger and older men to understand how aging changes this aspect of hemodynamics. A method to quantify the stresses generated by turbulence that act on the vessel wall was developed and evaluated using simulated flow data in Paper III, and in Paper V this method was utilized to examine the wall stresses of the carotid artery. The hemodynamics of vascular disease cannot be uncoupled from the anatomical changes the vessel wall undergoes, and therefore Paper IV developed and evaluated a semi-automatic method for quantifying several aspects of vessel wall composition. These developments, taken together, help generate more valuable information from imaging data, and can be pooled together with other methods to form a more comprehensive non-invasive examination for vascular disease.

Molecular Imaging: Computer Reconstruction and Practice

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Publisher : Springer Science & Business Media
ISBN 13 : 1402087527
Total Pages : 296 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Molecular Imaging: Computer Reconstruction and Practice by : Yves Lemoigne

Download or read book Molecular Imaging: Computer Reconstruction and Practice written by Yves Lemoigne and published by Springer Science & Business Media. This book was released on 2008-09-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reports the majority of lectures given during the NATO Advanced Study Institute ASI-982440, which was held at the European Scienti?c Institute of Archamps (ESI, Archamps – France) from November 9 to November 21, 2006. The ASI course was structured in two parts, the ?rst was dedicated to individual imaging techniques while the second is the object of this volume and focused on data modelling and processing and on image archiving and distribution. Courses devoted to nuclear medicine and digital imaging techniques are collected in a c- plementary volume of NATO Science Series entitled “Physics for Medical Imaging Applications” (ISBN 978-1-4020-5650-5). Every year in autumn ESI organises the European School of Medical Physics, which covers a large spectrum of topics ranging from Medical Imaging to Rad- therapy, over a period of ?ve weeks. Thanks to the Cooperative Science and Te- nology sub-programme of the NATO Science Division, weeks two and three were replaced this year by the ASI course dedicated to “Molecular Imaging from Physical Principles to Computer Reconstruction and Practice”. This allowed the participation ofexpertsandstudentsfrom20differentcountries,withdiverseculturalbackground and professional experience (Africa, America, Asia, and Europe). A further positive outcome of NATO ASI participation is the publication of this book, which contains the lectures series contributed by speakers during the second week of the ASI.

Innovative Developments in Multi-Modality Elastography

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832506801
Total Pages : 235 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Innovative Developments in Multi-Modality Elastography by : Simon Chatelin

Download or read book Innovative Developments in Multi-Modality Elastography written by Simon Chatelin and published by Frontiers Media SA. This book was released on 2022-11-23 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Medical Imaging

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Publisher : SPIE Press
ISBN 13 : 9780819436238
Total Pages : 976 pages
Book Rating : 4.4/5 (362 download)

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Book Synopsis Handbook of Medical Imaging by : Jacob Beutel

Download or read book Handbook of Medical Imaging written by Jacob Beutel and published by SPIE Press. This book was released on 2000 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes concurrent engineering developments that affect or are expected to influence future development of digital diagnostic imaging. It also covers current developments in Picture Archiving and Communications System (PACS) technology, with particular emphasis on integration of emerging imaging technologies into the hospital environment.

Physics for Medical Imaging Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 1402056532
Total Pages : 403 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Physics for Medical Imaging Applications by : Yves Lemoigne

Download or read book Physics for Medical Imaging Applications written by Yves Lemoigne and published by Springer Science & Business Media. This book was released on 2007-06-14 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the fundamental aspects of digital imaging and covers four main themes: ultrasound techniques and imaging applications, magnetic resonance and MPJ in hospital, digital imaging with X-rays, and emission tomography (PET and SPECT). Each topic is developed by analyzing the underlying physics principles and their implementation, quality and safety aspects, clinical performance, and recent advancements in the field.

Implantable Technologies

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839165367
Total Pages : 323 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Implantable Technologies by : Ved Srivastava

Download or read book Implantable Technologies written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2021-10-20 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.

The Physics of Medical Imaging

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Publisher : CRC Press
ISBN 13 : 9781439822081
Total Pages : 656 pages
Book Rating : 4.8/5 (22 download)

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Book Synopsis The Physics of Medical Imaging by : S. Webb

Download or read book The Physics of Medical Imaging written by S. Webb and published by CRC Press. This book was released on 1988-01-01 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physics of Medical Imaging reviews the scientific basis and physical principles underpinning imaging in medicine. It covers the major imaging methods of x-radiology, nuclear medicine, ultrasound, and nuclear magnetic resonance, and considers promising new techniques. Following these reviews are several thematic chapters that cover the mathematics of medical imaging, image perception, computational requirements, and techniques. Throughout the book, the author encourages readers to consider key questions concerning imaging. This profusely illustrated and extensively indexed text is accessible to graduate physical scientists, advanced undergraduates, and research students. It logically complements books on applications of imaging techniques in medicine, making it useful for clinicians as well.

The Essential Physics of Medical Imaging Study Guide

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975103270
Total Pages : 1240 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis The Essential Physics of Medical Imaging Study Guide by : Jerrold T. Bushberg

Download or read book The Essential Physics of Medical Imaging Study Guide written by Jerrold T. Bushberg and published by Lippincott Williams & Wilkins. This book was released on 2022-07-14 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely regarded as the cornerstone text in the field, the successful series of editions continues to follow the tradition of a clear and comprehensive presentation of the physical principles and operational aspects of medical imaging. The Essential Physics of Medical Imaging, 4th Edition, is a coherent and thorough compendium of the fundamental principles of the physics, radiation protection, and radiation biology that underlie the practice and profession of medical imaging. Distinguished scientists and educators from the University of California, Davis, provide up-to-date, readable information on the production, characteristics, and interactions of non-ionizing and ionizing radiation, magnetic fields and ultrasound used in medical imaging and the imaging modalities in which they are used, including radiography, mammography, fluoroscopy, computed tomography, magnetic resonance, ultrasound, and nuclear medicine. This vibrant, full-color text is enhanced by more than 1,000 images, charts, and graphs, including hundreds of new illustrations. This text is a must-have resource for medical imaging professionals, radiology residents who are preparing for Core Exams, and teachers and students in medical physics and biomedical engineering.

Principles and Advanced Methods in Medical Imaging and Image Analysis

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Author :
Publisher :
ISBN 13 : 9814476064
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Principles and Advanced Methods in Medical Imaging and Image Analysis by :

Download or read book Principles and Advanced Methods in Medical Imaging and Image Analysis written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hepatocellular Carcinoma

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Publisher : Springer
ISBN 13 : 3319342142
Total Pages : 596 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Hepatocellular Carcinoma by : Brian I. Carr

Download or read book Hepatocellular Carcinoma written by Brian I. Carr and published by Springer. This book was released on 2016-08-26 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: • Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. "This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology "...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease

Biomechanics of the Brain

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Publisher : Springer
ISBN 13 : 3030049965
Total Pages : 353 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Biomechanics of the Brain by : Karol Miller

Download or read book Biomechanics of the Brain written by Karol Miller and published by Springer. This book was released on 2019-08-08 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition presents an authoritative account of the current state of brain biomechanics research for engineers, scientists and medical professionals. Since the first edition in 2011, this topic has unquestionably entered into the mainstream of biomechanical research. The book brings together leading scientists in the diverse fields of anatomy, neuroimaging, image-guided neurosurgery, brain injury, solid and fluid mechanics, mathematical modelling and computer simulation to paint an inclusive picture of the rapidly evolving field. Covering topics from brain anatomy and imaging to sophisticated methods of modeling brain injury and neurosurgery (including the most recent applications of biomechanics to treat epilepsy), to the cutting edge methods in analyzing cerebrospinal fluid and blood flow, this book is the comprehensive reference in the field. Experienced researchers as well as students will find this book useful.