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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arthur Lesk
Publisher : Oxford University Press, USA
ISBN 13 : 0199541302
Total Pages : 476 pages
Book Rating : 4.1/5 (995 download)
Download or read book Introduction to Protein Science written by Arthur Lesk and published by Oxford University Press, USA. This book was released on 2010-03-25 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its function.
Author : Arthur M. Lesk
Publisher : Turtleback
ISBN 13 : 9780613919517
Total Pages : 347 pages
Book Rating : 4.9/5 (195 download)
Download or read book Introduction To Protein Architecture written by Arthur M. Lesk and published by Turtleback. This book was released on 2000-01-01 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: NULL
Author : Lvov/Mohwald
Publisher : CRC Press
ISBN 13 : 9780824782368
Total Pages : 410 pages
Book Rating : 4.7/5 (823 download)
Download or read book Protein Architecture written by Lvov/Mohwald and published by CRC Press. This book was released on 1999-09-29 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considers the design, structure and biological activity of ordered films comprised of proteins, polymers, amphiphile molecules and colloidal particles, and assesses the ability of protein/polyion multilayers to mimic living organelles. The book discusses how to reach predetermined locations with proteins and orient molecules while preserving their bioactivity.
Author : Gregory A. Petsko
Publisher : New Science Press
ISBN 13 : 0878936637
Total Pages : 220 pages
Book Rating : 4.8/5 (789 download)
Download or read book Protein Structure and Function written by Gregory A. Petsko and published by New Science Press. This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.
Author : Nobuhiko Saito
Publisher : World Scientific
ISBN 13 : 9810247109
Total Pages : 155 pages
Book Rating : 4.8/5 (12 download)
Download or read book The Physical Foundation of Protein Architecture written by Nobuhiko Saito and published by World Scientific. This book was released on 2001 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: A protein requires its own three-dimensional structure for its biological activity. If a chemical agent is added, the biological activity is lost, and the three dimensional structure is destroyed to become a random coil state. But when the chemical agent is removed, the biological activity is recovered, implying that the random coil state turns back into the original complex structure spontaneously. This is an astonishing event. The Physical Foundation of Protein Architecture is intended to solve this mystery from the physicochemical basis by elucidating the mechanism of various processes in protein folding. The main features of protein folding are shown to be described by the island model with long range hydrophobic interaction which is capable of finding the specific residue, and the lampshade criterion for disulfide bonding. Various proteins with known structure are refolded, with the purpose of uncovering the mechanism of protein folding. In addition, ab initio method for predicting protein structure from its amino acid sequence is proposed.
Author : Daniel Chasman
Publisher : CRC Press
ISBN 13 : 0824748166
Total Pages : 534 pages
Book Rating : 4.8/5 (247 download)
Download or read book Protein Structure written by Daniel Chasman and published by CRC Press. This book was released on 2003-03-18 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. A valuable reference, this book reflects current trends in the effort to solve new structures arising from genome initiatives, details methods to detect and identify errors in the prediction of protein structural models, and outlines challenges in the conversion of routine processes into high-throughput platforms.
Author : Carl Ivar Branden
Publisher : Garland Science
ISBN 13 : 1136969896
Total Pages : 425 pages
Book Rating : 4.1/5 (369 download)
Download or read book Introduction to Protein Structure written by Carl Ivar Branden and published by Garland Science. This book was released on 2012-03-26 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815323051Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their bio
Author : Arthur M. Lesk
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.3/5 (91 download)
Download or read book Protein Architecture written by Arthur M. Lesk and published by Oxford University Press, USA. This book was released on 1991 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern computer graphics transforms protein structures into visually exciting images. 'Protein Architecture: A Practical Approach' shows the reader how to visualize protein structures, and how to design an illustration to help understand and appreciate the variety of protein folding patterns.
Author : Arthur M. Lesk
Publisher : Oxford University Press, USA
ISBN 13 : 9780198716846
Total Pages : 0 pages
Book Rating : 4.7/5 (168 download)
Download or read book Introduction to Protein Science written by Arthur M. Lesk and published by Oxford University Press, USA. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are essential to life, having a vital role in all living organisms. They are the ultimate micro machines: some are building blocks, joining with other substances to make the cells from which we are all formed. Some are catalysts, speeding up essential biochemical reactions to keep our cells alive. Yet others help cells to communicate, to move, and to build up the complex mix of tissues that make up our bodies. Introduction to Protein Science provides a broad ranging introduction to the contemporary study of proteins suitable for students on biosciences degrees internationally. Starting by describing the structure of proteins and how these structures can be studied, the book goes on to illustrate the wide range of functions that proteins have, showing how the shape of a protein is intimately linked to the function that it has. The book then describes how new experimental and computational techniques are helping us to predict a protein s structure and function, and how this is paving the way for us to design new proteins with specific characteristics, with exciting implications in areas such as drug design. Written by Arthur Lesk, the author of the highly successful Introduc
Author : James J. L'Italien
Publisher : Springer Science & Business Media
ISBN 13 : 1461317878
Total Pages : 780 pages
Book Rating : 4.4/5 (613 download)
Download or read book Proteins written by James J. L'Italien and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume surveys the current status of many of the important methods and approaches which are central to the study of protein structure and function. Many of the articles in this volume are written to emphasize the general utility of the method or approach which is at its core, and to provide sufficient literature references to enable the reader to adapt the method or approach to other applications. It is hoped that this volume will provide a source from which newcomers as well as experienced scient ists may becom& more familiar with recent developments and future trends in some of the important areas of protein research. The articles which comprise this book are selected proceedings from the Symposium of American Protein Chemists, which was held in San Diego, California, September 30 to October 3, 1985. The goal of the organizers of this first symposium was to provide a forum for discussion and inter action among scientists whose interests span the broad spectrum of protein structure and function research. The concept and timing of the symposium well received as evidenced by the approximately 500 delegates to the was symposium. The inaugural meeting was marked by a strong scientific pro gram with over 140 papers presented in either a lecture or poster format.
Author : Huzefa Rangwala
Publisher : John Wiley & Sons
ISBN 13 : 111809946X
Total Pages : 611 pages
Book Rating : 4.1/5 (18 download)
Download or read book Introduction to Protein Structure Prediction written by Huzefa Rangwala and published by John Wiley & Sons. This book was released on 2011-03-16 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.
Author : Daniel J. Rigden
Publisher : Springer
ISBN 13 : 9402410694
Total Pages : 509 pages
Book Rating : 4.4/5 (24 download)
Download or read book From Protein Structure to Function with Bioinformatics written by Daniel J. Rigden and published by Springer. This book was released on 2017-04-06 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure, covering all structural classes from globular proteins and their membrane-resident counterparts to amyloid structures and intrinsically disordered proteins. The book is split into two broad sections, the first covering methods to generate or infer protein structure, the second dealing with structure-based function annotation. Each chapter is written by world experts in the field. The first section covers methods ranging from traditional homology modelling and fold recognition to fragment-based ab initio methods, and includes a chapter, new for the second edition, on structure prediction using evolutionary covariance. Membrane proteins and intrinsically disordered proteins are each assigned chapters, while two new chapters deal with amyloid structures and means to predict modes of protein-protein interaction. The second section includes chapters covering functional diversity within protein folds and means to assign function based on surface properties and recurring motifs. Further chapters cover the key roles of protein dynamics in protein function and use of automated servers for function inference. The book concludes with two chapters covering case studies of structure prediction, based respectively on crystal structures and protein models, providing numerous examples of real-world usage of the methods mentioned previously. This book is targeted at postgraduate students and academic researchers. It is most obviously of interest to protein bioinformaticians and structural biologists, but should also serve as a guide to biologists more broadly by highlighting the insights that structural bioinformatics can provide into proteins of their interest.
Author : Ying Xu
Publisher : Springer Science & Business Media
ISBN 13 : 0387683720
Total Pages : 408 pages
Book Rating : 4.3/5 (876 download)
Download or read book Computational Methods for Protein Structure Prediction and Modeling written by Ying Xu and published by Springer Science & Business Media. This book was released on 2007-08-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume One of this two-volume sequence focuses on the basic characterization of known protein structures, and structure prediction from protein sequence information. Eleven chapters survey of the field, covering key topics in modeling, force fields, classification, computational methods, and structure prediction. Each chapter is a self contained review covering definition of the problem and historical perspective; mathematical formulation; computational methods and algorithms; performance results; existing software; strengths, pitfalls, challenges, and future research.
Author : Michael J. E. Sternberg
Publisher : Oxford University Press, USA
ISBN 13 : 0191588997
Total Pages : 322 pages
Book Rating : 4.1/5 (915 download)
Download or read book Protein Structure Prediction : A Practical Approach written by Michael J. E. Sternberg and published by Oxford University Press, USA. This book was released on 1996-11-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms. - ;The prediction of the three-dimensional structure of a protein from its sequence is a problem faced by an ever-increasing number of biological scientists as they strive to utilize genetic information. The increasing sizes of the sequence and structural databases, the improvements in computing power, and the deeper understanding of the principles of protein structure have led to major developments in the field in the last few years. This book presents practical computer-based methods using the latest computer modelling algorithms. -
Author : Concettina Guerra
Publisher : Springer Science & Business Media
ISBN 13 : 3540401040
Total Pages : 161 pages
Book Rating : 4.5/5 (44 download)
Download or read book Mathematical Methods for Protein Structure Analysis and Design written by Concettina Guerra and published by Springer Science & Business Media. This book was released on 2003-06-25 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this volume reproduce contributions by leading sch- arstoaninternationalschoolandworkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs for a mix of heterogeneous expertise spanning biology, chemistry, mathematics, computer science, and statistics, among others. Some of the problems encountered in this area are not only important for the scienti?c challenges they pose, but also for the opportunities they disclose intermsofmedicalandindustrialexploitation. Atypicalexampleiso?eredby protein-drug interaction (docking), a problem posing daunting computational problems at the crossroads of geometry, physics and chemistry, and, at the same time, a problem with unimaginable implications for the pharmacopoeia of the future. The schoolfocused on problems posed by the study of the mechanisms - hind protein folding, and explored di?erent ways of attacking these problems under objective evaluations of the methods. Together with a relatively small core of consolidated knowledge and tools, important re?ections were brought to this e?ort by studies in a multitude of directions and approaches. It is obviously impossible to predict which, if any, among these techniques will prove completely successful, but it is precisely the implicit dialectic among them that best conveys the current ?avor of the ?eld. Such unique diversity and richness inspired the format of the meeting, and also explains the slight departure of the present volume from the typical format in this series: the exposition of the current sediment is complemented here by a selection of quali?ed specialized contributions.
Author : Stephen H White
Publisher : Springer
ISBN 13 : 1461475155
Total Pages : 403 pages
Book Rating : 4.4/5 (614 download)
Download or read book Membrane Protein Structure written by Stephen H White and published by Springer. This book was released on 2013-05-27 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of receptors, ion channels, and other membrane proteins require a solid understanding of the structural principles of these important biomolecules. Membrane protein structure is, however, a very challenging field. The structures of only three types of transmembrane proteins have been determined to moderate or high resolution during the last two decades, a period during which the amino acid sequences of hundreds, if not thousands, of membrane proteins have been reported. As a result, the creation of structural models to serve as guides for studies of receptors, channels, and other membrane proteins has become crucially important. This book has been assembled in order to share the experiences and findings of expert researchers in protein structure and structure-prediction methods as well as membrane biophysics and lipid physical chemistry, whose work establishes the basis for the development of suitable model structures. The reviews presented here emphasize fundamental ideas and provide an entry to the diverse and complex literature. The four major sections deal with the general nature of the membrane protein structure problem, biochemical and molecular biological approaches to protein topology, direct structural methods, and model and physicochemical approaches. The work will be of interest to physiologists, cellular and molecular biologists, biophysicists, and biochemists working on the function of membrane proteins such as receptors, ion channels, and transporters, as well as senior graduate students and independent investigators.
