Proof of Concept Study of a Semiconductor Compton Camera to be Used for Prompt Gamma Ray Imaging During Proton Therapy

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Proof of Concept Study of a Semiconductor Compton Camera to be Used for Prompt Gamma Ray Imaging During Proton Therapy by : Hamed Abdulrzaq T. Alshammari

Download or read book Proof of Concept Study of a Semiconductor Compton Camera to be Used for Prompt Gamma Ray Imaging During Proton Therapy written by Hamed Abdulrzaq T. Alshammari and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design Study of a Compton Camera for Prompts-gamma Imaging During Ion Beam Therapy

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (868 download)

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Book Synopsis Design Study of a Compton Camera for Prompts-gamma Imaging During Ion Beam Therapy by : Marie-Hélène Richard

Download or read book Design Study of a Compton Camera for Prompts-gamma Imaging During Ion Beam Therapy written by Marie-Hélène Richard and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion beam therapy is an innovative radiotherapy technique using mainly carbon ion and proton irradiations. Its aim is to improve the current treatment modalities. Because of the sharpness of the dose distributions, a control of the dose if possible in real time is highly desirable. A possibility is to detect the prompt gamma rays emitted subsequently to the nuclear fragmentations occurring during the treatment of the patient. In a first time two different Compton cameras (double and single scattering) have been optimised by means of Monte Carlo simulations. The response of the camera to a photon point source with a realistic energy spectrum was studied. Then, the response of the camera to the irradiation of a water phantom by a proton beam was simulated. It was first compared with measurement performed with small-size detectors. Then, using the previous measurements, we evaluated the counting rates expected in clinical conditions. In the current set-up of the camera, these counting rates are pretty high. Pile up and random coincidences will be problematic. Finally we demonstrate that the detection system is capable to detect a longitudinal shift in the Bragg peak of +or- 5 mm, even with the current reconstruction algorithm.

Implementation and Characterization of the Data Acquisition System of a Compton Camera for Prompt Gamma Imaging in Protontherapy

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (126 download)

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Book Synopsis Implementation and Characterization of the Data Acquisition System of a Compton Camera for Prompt Gamma Imaging in Protontherapy by : Cairo Pimenta Cheble Caplan

Download or read book Implementation and Characterization of the Data Acquisition System of a Compton Camera for Prompt Gamma Imaging in Protontherapy written by Cairo Pimenta Cheble Caplan and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hadrontherapy uses a beam of charged particles (protons or carbon ions) to destroy tumour cells. Compared to conventional radiotherapy hadrontherapy represents a promising technique to treat cancer because of its concentrated dose delivery within the Bragg peak. Monitoring of dose delivery can thus be addressed by verifying the range of the beam particles.CLaRyS, which stands for online control of hadrontherapy by secondary radiation, is a project regrouping several laboratories that aims at improving dose delivery control by imaging the emission of prompt-gamma rays issued from inelastic collisions of the beam particles with target nuclei. This requires to detect prompt-gamma rays using either a mechanical or the electronic collimation resulting from the Compton interactions of the gamma rays in a scatterer.As part of this development, a high-performance and compact Back-End (BE) electronics was developed at CPPM to perform data acquisition from the detectors through 34 optical links of 3 Gb/s. Data are packed and sent to a PC on a 1 Gb/s Ethernet link, guaranteeing 300 Mb/s throughput as specified for the Compton camera by Monte Carlo simulations for a beam intensity of 10 power of 8 proton/s. My thesis work comprised the development of the FPGA firmware for the BE electronics of CLaRyS, while contributing to the development and evaluation of its detection system. Measurements with the collimated camera and beam hodoscope were performed on the 65 MeV proton beam line of the Mediterranean Protontherapy Institute in Nice.

Proton Therapy Physics

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Publisher : CRC Press
ISBN 13 : 1439836450
Total Pages : 691 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Proton Therapy Physics by : Harald Paganetti

Download or read book Proton Therapy Physics written by Harald Paganetti and published by CRC Press. This book was released on 2016-04-19 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

On Compton Imaging

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ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (794 download)

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Book Synopsis On Compton Imaging by : Sara Mattafirri

Download or read book On Compton Imaging written by Sara Mattafirri and published by . This book was released on 2010 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract On Compton Imaging by Sara Mattafirri Doctor of Philosophy in Engineering-Nuclear Engineering University of California, Berkeley Professor Stanley G. Prussin, Co-Chair Professor Kai Vetter, Co-Chair Professor Jasmina Vujic Professor Steven Conolly The feasibility of producing an image of radioactivity distribution within a patient or confined region of space using information carried by the gamma-rays emitted from the source is investigated. The imaging approach makes use of parameters related to the gamma-rays which undergo Compton scattering within a detection system, it does not involve the use of pin-holes, and it employs gamma-rays of energy ranging from a few hundreds of keVs to MeVs. Energy range of the photons and absence of pin-holes aim to provide larger pool of radioisotopes and larger efficiency than other emission imaging modalities, such as single photon emission computed tomography and positron emission tomography, making it possible to investigate larger pool of functions and smaller radioactivity doses. The observables available to produce the image are the gamma-ray position of interaction and energy deposition during Compton scattering within the detection systems. Image reconstruction methodologies such as backprojection and list-mode maximum likelihood expectation maximization algorithm are characterized and applied to produce images of simulated and experimental sources on the basis of the observed parameters. Given the observables and image reconstruction methodologies, imaging systems based on minimizing the variation of the impulse response with position within the field of view are developed. The approach allows imaging of three-dimensional sources when an imaging system which provides full 4 pi view of the object is used and imaging of two-dimensional sources when a single block-type detector which provides one view of the object is used. Geometrical resolution of few millimeters is obtained at few centimeters from the detection system if employing gamma-rays of energy in the order of few hundreds of keVs and current state of the art semi-conductor detectors; At this level of resolution, detection efficiency is in the order of 10-̂3 at few centimeters from the detector when a single block detector few centimeters in size is used. The resolution significantly improves with increasing energy of the photons and it degrades roughly linearly with increasing distance from the detector; Larger detection efficiency can be obtained at the expenses of resolution or via targeted configurations of the detector. Results pave the way for image reconstruction of practical gamma-ray emitting sources.

Magnetic Particle Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 364204199X
Total Pages : 211 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Magnetic Particle Imaging by : Tobias Knopp

Download or read book Magnetic Particle Imaging written by Tobias Knopp and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.

Semiconductor Detector Systems

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Publisher : OUP Oxford
ISBN 13 : 0191523658
Total Pages : 513 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Semiconductor Detector Systems by : Helmuth Spieler

Download or read book Semiconductor Detector Systems written by Helmuth Spieler and published by OUP Oxford. This book was released on 2005-08-25 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Semiconductor sensors patterned at the micron scale combined with custom-designed integrated circuits have revolutionized semiconductor radiation detector systems. Designs covering many square meters with millions of signal channels are now commonplace in high-energy physics and the technology is finding its way into many other fields, ranging from astrophysics to experiments at synchrotron light sources and medical imaging. This book is the first to present a comprehensive discussion of the many facets of highly integrated semiconductor detector systems, covering sensors, signal processing, transistors and circuits, low-noise electronics, and radiation effects. The diversity of design approaches is illustrated in a chapter describing systems in high-energy physics, astronomy, and astrophysics. Finally a chapter "Why things don't work" discusses common pitfalls. Profusely illustrated, this book provides a unique reference in a key area of modern science.

Radiation Oncology Physics

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Publisher : IAEA
ISBN 13 :
Total Pages : 704 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiation Oncology Physics by : International Atomic Energy Agency

Download or read book Radiation Oncology Physics written by International Atomic Energy Agency and published by IAEA. This book was released on 2005 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is aimed at students and teachers involved in teaching programmes in field of medical radiation physics, and it covers the basic medical physics knowledge required in the form of a syllabus for modern radiation oncology. The information will be useful to those preparing for professional certification exams in radiation oncology, medical physics, dosimetry or radiotherapy technology.

Particle Detectors

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Publisher : Oxford University Press
ISBN 13 : 0191899232
Total Pages : 949 pages
Book Rating : 4.1/5 (918 download)

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Book Synopsis Particle Detectors by : Hermann Kolanoski

Download or read book Particle Detectors written by Hermann Kolanoski and published by Oxford University Press. This book was released on 2020-06-30 with total page 949 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fundamentals of particle detectors as well as their applications. Detector development is an important part of nuclear, particle and astroparticle physics, and through its applications in radiation imaging, it paves the way for advancements in the biomedical and materials sciences. Knowledge in detector physics is one of the required skills of an experimental physicist in these fields. The breadth of knowledge required for detector development comprises many areas of physics and technology, starting from interactions of particles with matter, gas- and solid-state physics, over charge transport and signal development, to elements of microelectronics. The book's aim is to describe the fundamentals of detectors and their different variants and implementations as clearly as possible and as deeply as needed for a thorough understanding. While this comprehensive opus contains all the materials taught in experimental particle physics lectures or modules addressing detector physics at the Master's level, it also goes well beyond these basic requirements. This is an essential text for students who want to deepen their knowledge in this field. It is also a highly useful guide for lecturers and scientists looking for a starting point for detector development work.

Radiation Physics for Medical Physicists

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Publisher : Springer Science & Business Media
ISBN 13 : 3642008755
Total Pages : 774 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Radiation Physics for Medical Physicists by : Ervin B. Podgorsak

Download or read book Radiation Physics for Medical Physicists written by Ervin B. Podgorsak and published by Springer Science & Business Media. This book was released on 2010-02-02 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes basic knowledge of atomic, nuclear, and radiation physics that professionals need for efficient and safe use of ionizing radiation. Concentrating on the underlying principles of radiation physics, it covers prerequisite knowledge for medical physics courses on the graduate and post-graduate levels, providing the link between elementary physics on the one hand and the intricacies of the medical physics specialties on the other.

Medical Imaging Systems

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Publisher : Springer
ISBN 13 : 3319965204
Total Pages : 263 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Medical Imaging Systems by : Andreas Maier

Download or read book Medical Imaging Systems written by Andreas Maier and published by Springer. This book was released on 2018-08-02 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.

Radiation and Health

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Publisher : CRC Press
ISBN 13 : 0203166353
Total Pages : 241 pages
Book Rating : 4.2/5 (31 download)

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Book Synopsis Radiation and Health by : Thormod Henriksen

Download or read book Radiation and Health written by Thormod Henriksen and published by CRC Press. This book was released on 2002-09-05 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation and the effects of radioactivity have been known for more than 100 years. International research spanning this period has yielded a great deal of information about radiation and its biological effects and this activity has resulted in the discovery of many applications in medicine and industry including cancer therapy, medical diagnostics

Applications of Research Reactors

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Publisher : International Atomic Energy Agency
ISBN 13 : 9789201450104
Total Pages : 108 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Applications of Research Reactors by : International Atomic Energy Agency

Download or read book Applications of Research Reactors written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2014 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is a comprehensive study that reviews the current situation in a great number of applications of research reactors. It revises the contents of IAEA TECDOC-1234, The Applications of Research Reactors, giving detailed updates on each field of research reactor uses worldwide. Reactors of all sizes and capabilities can benefit from the sharing of current practices and research enabled via this updated version, which describes the requirements for practicing methods as diverse as neutron activation analysis, education and training, neutron scattering and neutron imaging, silicon doping and radioisotope production, material/fuel irradiation and testing, and some others. Many underutilised research reactors can learn how to diversify their technical capabilities, staff and potential commercial partners and users seeking research reactor services and products. The content of the publication has also been strengthened in terms of current issues facing the vast majority of research reactors by including sections describing user and customer relations as well as strategic planning considerations.

Medical Gamma-ray Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 84 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Gamma-ray Spectrometry by : D. A. Ross

Download or read book Medical Gamma-ray Spectrometry written by D. A. Ross and published by . This book was released on 1959 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:

SPECT and SPECT/CT

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Publisher : Thieme
ISBN 13 : 162623339X
Total Pages : 355 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis SPECT and SPECT/CT by : Chun K. Kim

Download or read book SPECT and SPECT/CT written by Chun K. Kim and published by Thieme. This book was released on 2017-06-14 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: FOUR STARS from Doody's Star Ratings™ Internationally renowned authorities in the field of hybrid imaging contribute firsthand expertise on the practical application of single-photon emission computed tomography (SPECT) and SPECT/CT. By combining clear anatomic markers from CT with functional knowledge from SPECT, SPECT/CT provides added value for patient evaluation and is becoming increasingly prevalent in routine clinical practice. Indeed, hybrid imaging is touted by many as a game changer in nuclear medicine. The first two chapters of this book provide a foundation for understanding SPECT and SPECT/CT technological principles, including the associated radiopharmaceuticals. The remaining chapters detail the utility of SPECT and SPECT/CT in clinical practice including neuroscience and pediatrics, as well as specific pathologies. The book concludes with in-depth discussion of select case studies. Key Features Efficacious use of SPECT and SPECT/CT for primary body systems, including the central nervous, cardiovascular, respiratory, and skeletal systems Value for the assessment of neoplastic disease, infection/inflammation, thyroid and parathyroid gland disorders Fourteen high-quality videos delineate specific techniques and clinical applications Meticulous, four-color graphics clearly elucidate key concepts Illustrative case studies offer educational teaching pearls Together, the concise, evidence-based text and wealth of SPECT/CT images deliver a solid knowledge base, enabling practitioners to learn the effective use of this technology. This must-have book is certain to be an invaluable resource for a diverse spectrum of practicing and trainee clinicians in fields such as radiology, nuclear medicine, and radiation oncology.

Physics in Nuclear Medicine

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Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Physics in Nuclear Medicine by : Simon R. Cherry

Download or read book Physics in Nuclear Medicine written by Simon R. Cherry and published by . This book was released on 2003 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, the authors provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labelled tracers. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.

Diagnostic Radiology Physics

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Publisher :
ISBN 13 : 9789201310101
Total Pages : 0 pages
Book Rating : 4.3/5 (11 download)

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Book Synopsis Diagnostic Radiology Physics by : International Atomic Energy Agency

Download or read book Diagnostic Radiology Physics written by International Atomic Energy Agency and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is aimed at students and teachers involved in programmes that train medical physicists for work in diagnostic radiology. It provides a comprehensive overview of the basic medical physics knowledge required in the form of a syllabus for the practice of modern diagnostic radiology. This makes it particularly useful for graduate students and residents in medical physics programmes. The material presented in the publication has been endorsed by the major international organizations and is the foundation for academic and clinical courses in both diagnostic radiology physics and in emerging areas such as imaging in radiotherapy.