Author : Soheir Kotob
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783848446063
Total Pages : 288 pages
Book Rating : 4.4/5 (46 download)
Book Synopsis Promising Role of Natural Products Against Alzheimer's Disease by : Soheir Kotob
Download or read book Promising Role of Natural Products Against Alzheimer's Disease written by Soheir Kotob and published by LAP Lambert Academic Publishing. This book was released on 2014-03 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most well-known type of neurodegenerative dementia is Alzheimer's disease (AD) in elderly, an age-dependent neurodegenerative disease, proceeds at stages from mild, moderate to severe and gradually destroys the brain. Advancing age, age related diseases such as cardiovascular disease, diabetes, obesity and cancer, head trauma and exposure to heavy metals such as Al, cupper, iron and zinc are the major cause for AD. The current study was designed to explore the potent role of Salvia triloba, Piper nigrum, Ruta graveolens and Pegenum harmala in management of neuroinflammatory insults characterizing AD in experimental rat model. The present study suggested that the studied medicinal plant extracts have a different degree of potentiality in alleviating AD. This promising effect was achieved through their powerful anti-cholinesterase activity, anti-inflammatory property and anti-apoptotic capacity. The current study represented good therapeutic approach for intervention against progressive neurological damage associated with AD.