Nutraceuticals in Brain Health and Beyond

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Author :
Publisher : Academic Press
ISBN 13 : 0128206101
Total Pages : 476 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nutraceuticals in Brain Health and Beyond by : Dilip Ghosh

Download or read book Nutraceuticals in Brain Health and Beyond written by Dilip Ghosh and published by Academic Press. This book was released on 2020-11-12 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer’s, Parkinson’s, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses "herb-nutra psychiatry" which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health. Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health. • Addresses nutritional psychiatry and cognitive health at all stages of the lifespan • Contains extensive coverage of vitamins, minerals, botanicals, and other nutrients • Offers novel insight into cognitive dysfunctions including depression and other neurodegenerative disorders • Explores the role of genomics and epigenetics, including discussion of the gut–brain axis

Brain Health for Life

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Author :
Publisher :
ISBN 13 : 9781629011547
Total Pages : 306 pages
Book Rating : 4.0/5 (115 download)

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Book Synopsis Brain Health for Life by : Karen V. Unger

Download or read book Brain Health for Life written by Karen V. Unger and published by . This book was released on 2014-11 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 5.2 million people in the U.S. were suffering from Alzheimer's in 2014, a number that is expected to triple by 2050. There is growing evidence that diet and lifestyle can affect your brain and impact your cognitive aging. Learn what to eat, what to avoid, and how to change your lifestyle to prevent disease, be vibrantly healthy and intellectually sharp throughout your life. Brain Health for Life: Beyond Pills, Politics, and Popular Diets will tell you: How the current food supply and environment is making you sick How misinformation and outdated medical practices are hurting you How the brain and body work together to promote overall health How nutritious food and regular exercise can protect your brain How to avoid inflammation, the source of many preventable diseases How simple lifestyle changes can enhance your brain health"

Nutrition for Brain Health and Cognitive Performance

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Author :
Publisher : CRC Press
ISBN 13 : 1466570032
Total Pages : 373 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Nutrition for Brain Health and Cognitive Performance by : Talitha Best

Download or read book Nutrition for Brain Health and Cognitive Performance written by Talitha Best and published by CRC Press. This book was released on 2015-06-12 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public awareness of the role diet plays in brain function has been steadily increasing. This has led to significant development of new products, dietary supplements, functional foods, nutraceuticals and public health recommendations for maintaining brain function. Nutrition for Brain Health and Cognitive Performance presents a detailed and innovative scientific summary of nutrition–cognition research to provide valuable information regarding nutrition and lifestyle choices for cognitive health. Internationally recognised scholars along with the next generation of researchers have contributed chapters that present a valuable resource for health professionals, teachers, researchers and the general public. The book critically reviews the evidence surrounding the impact of dietary patterns and nutrition on brain function and cognitive performance. It covers diverse topics such as: Innovative new technologies that assess brain function Tools for measuring mood and its relation to nutrition How a diet rich in fruits and vegetables coupled with low consumption of meats can prevent cognitive decline in ageing adults Effects of glucose, omega 3s, vitamins and minerals, nutraceuticals and flavonoids on cognitive performance Cognitive benefits of herbal extracts such as ginseng, ginkgo biloba and green tea Use of technology such as neuroimaging and noninvasive brain stimulation (NBS) to capture nutrition effects on cognition and brain function Presenting state-of-the-art scientific evidence, challenges, and potential applications within this exciting field, the book promotes and extends the research, teaches the process of research in this area, and promotes a collaborative understanding of the field between industry and academia. It gives you a balance of rigorous scientific information and analysis on the impact of dietary patterns, nutritional components and research processes to support brain health and performance claims and knowledge.

Bioactive Nutraceuticals for Brain Disorders

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Author :
Publisher : Nova Science Publishers
ISBN 13 : 9781536194630
Total Pages : 0 pages
Book Rating : 4.1/5 (946 download)

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Book Synopsis Bioactive Nutraceuticals for Brain Disorders by : Aman B. Upaganlawar

Download or read book Bioactive Nutraceuticals for Brain Disorders written by Aman B. Upaganlawar and published by Nova Science Publishers. This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Over the past several years research concerning brain health and nutraceuticals has received much attention due to their potential neuroprotective properties and few or no side effects. Nutraceuticals exert copious effects in several biological processes, including antioxidant defenses, cell proliferation and differentiation, gene expression, signal transduction, and safeguarding of mitochondrial integrity. It is very likely that the brain health of an individual is affected by his or her dietary pattern. Intake of a well-nourished diet in the earliest stages of life builds a strong foundation of the brain which helps to maintain brain health in later stages of life. On the other hand, nutritional deficiency can disrupt the structure and function of the human nervous system and increases the risk of brain disorders and early death, affecting all age groups. Although nutraceuticals are popular for health, wellbeing, and illness, the efficacy of common supplements to combat brain disorders is not clearly understood. Bioactive Nutraceuticals for Brain Disorders aims to describe the importance of nutraceutical intervention on different brain disorders to highlight the therapeutic as well as preventive potential"--

Beyond Alzheimer's

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Author :
Publisher : Government Institutes
ISBN 13 : 1590771583
Total Pages : 273 pages
Book Rating : 4.5/5 (97 download)

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Book Synopsis Beyond Alzheimer's by : Scott D. Mendelson

Download or read book Beyond Alzheimer's written by Scott D. Mendelson and published by Government Institutes. This book was released on 2009-09-16 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking explanation of the causes and treatment of Alzheimer's disease rests on the author's belief that Alzheimer's is merely one of several types of dementia—and that in most cases dementia is avoidable. He further explains that the various forms of dementia may well be different manifestations of the same set of underlying problems. Rather than being the inevitable result of aging, the author asserts dementia is primarily the result of bad diet, stress, lack of mental and physical exercise, and other poor lifestyle choices. Dr. Mendelson begins his book with a straightforward explanation of how the brain ages—physically, structurally, and chemically. He then explains the various methods for diagnosing dementia, as well as how it can often be misdiagnosed if a person has suffered a head injury or stroke, has a hormone or vitamin deficiency, or is taking a medication whose side effects can mimic dementia. The remainder of the book is prescriptive, and offers hope to both Alzheimer's patients and their caregivers by recommending scientifically tested herbs, vitamins and nutraceuticals that can help mitigate or delay the effects of dementia. Finally, the author suggests lifestyle changes that might help a person avoid dementia altogether, commonsense health tips that include steps to prevent heart disease and diabetes, treatment for sleep apnea, maintaining an ideal body weight, and even engaging in a more active social life.

Nutraceuticals

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Author :
Publisher : Academic Press
ISBN 13 : 0128212462
Total Pages : 1397 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nutraceuticals by : Ramesh C Gupta

Download or read book Nutraceuticals written by Ramesh C Gupta and published by Academic Press. This book was released on 2021-01-27 with total page 1397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines. Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects Provides effective tools to evaluate the potential toxicity of any nutraceutical Includes details of regulatory issues as written by international experts

Preventing Cognitive Decline and Dementia

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Author :
Publisher : National Academies Press
ISBN 13 : 0309459591
Total Pages : 181 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Preventing Cognitive Decline and Dementia by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Varcarolis's Canadian Psychiatric Mental Health Nursing - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323778801
Total Pages : 741 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Varcarolis's Canadian Psychiatric Mental Health Nursing - E-Book by : Cheryl L. Pollard

Download or read book Varcarolis's Canadian Psychiatric Mental Health Nursing - E-Book written by Cheryl L. Pollard and published by Elsevier Health Sciences. This book was released on 2022-05-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain the knowledge and skills you need to provide psychiatric mental health nursing care in Canada! Varcarolis's Canadian Psychiatric Mental Health Nursing, 3rd Edition uses a practical clinical perspective to provide a clear understanding of this often-intimidating subject. It provides a foundation in nursing techniques and a guide to psychobiological disorders such as bipolar and depressive disorders, trauma interventions, and interventions for distinct populations such as children and older adults. Adapted to meet the needs of Canadian nurses by Cheryl L. Pollard and Sonya L. Jakubec, this market-leading text prepares you for practice with real-world examples presented within a Canadian legal, ethical, and cultural context. Canadian focus throughout includes key considerations such as our nation’s cultural and social diversity with federal/provincial/territorial distinctions. Canadian research and statistics reflect mental health and mental health practice in Canada. Research Highlight boxes are updated with examples of Indigenous research methodologies by Indigenous researchers and settler allies. DSM-5 boxes provide criteria for disorders covered by the American Psychological Association. Learning features include key terms and concepts, learning objectives, key points to remember, critical thinking, and chapter reviews, reinforcing important information and helping to apply textbook content to the clinical setting. Assessment Guidelines boxes summarize the steps of patient assessment for various disorders. Drug Treatment boxes feature the most current generic and trade names for drugs used in Canada. Patient and Family Teaching boxes provide important details that should be discussed with patients and care givers. Integrative Therapy boxes highlight the different types of therapy may be used to enhance treatment. Considering Culture boxes discuss the importance of cultural safety in providing competent care to diverse populations within various clinical situations. NEW! Safety Tip boxes highlight important issues of safety for psychiatric mental health care, patient experiences, and nursing interventions. NEW! Added mental health content covers Indigenous populations, migrant populations, and gender differences with a focus on cultural safety, equity-informed approaches, relational and trauma-informed practices. Updated Chapter 29 covers recovery, survivorship, and public mental health approaches. Enhanced topics include substance use disorders, harm reduction, and support among nurses; changes related to Medical Assistance in Dying (MAiD) legislation; and mental health in view of climate change and the COVID-19 pandemic.

Ayurvedic Herbal Preparations in Neurological Disorders

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Author :
Publisher : Elsevier
ISBN 13 : 0443153965
Total Pages : 752 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Ayurvedic Herbal Preparations in Neurological Disorders by : Murali Muralidhara

Download or read book Ayurvedic Herbal Preparations in Neurological Disorders written by Murali Muralidhara and published by Elsevier. This book was released on 2023-08-07 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer’s disease, Parkinson’s disease, depressive mood disorders, epilepsy, schizophrenia, and more. More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention. Provides a focused introduction to major Ayurvedic plants and their therapeutic potential in the management of neurodegenerative diseases Discusses various mechanisms underlying the neuromodulatory potential of several ayurvedic herbal preparations in preclinical and clinical settings Examines major subsets of ayurvedic plants (e.g., Bacopa monnieri, Centella asiatica, Withaniasomnifera, and others) and potential of several other plants in various neurological disorders Outlines the importance of integrative approaches along with existing treatments in the intervention/management of depressive mood disorders, epilepsy, schizophrenia, and more Highlights recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection

Preserving Brain Health in a Toxic Age

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Author :
Publisher : Rowman & Littlefield
ISBN 13 : 1538158086
Total Pages : 281 pages
Book Rating : 4.5/5 (381 download)

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Book Synopsis Preserving Brain Health in a Toxic Age by : Arnold R. Eiser

Download or read book Preserving Brain Health in a Toxic Age written by Arnold R. Eiser and published by Rowman & Littlefield. This book was released on 2021-10-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to reduce the impact of environmental toxins on brain development, functioning, and health. The human brain is a marvelously complex organ that has evolved great new capabilities over the past 250,000 years. During most of that period, daily life was vastly different from our lives today. Exercise was not optional - one literally had to run for one’s life, livelihood, and sustenance. The Stone Age diet was not a fad, but the only food available. Periods of fasting arose from food scarcity, and hence the earliest keto-diet was commonplace. Life changed greatly with the advent of agriculture and industry. Diseases that were previously unknown or uncommon began to surface as by-products of civilization’s advance. Changes in our ways of living have altered the nature of illness as well as its diagnosis and treatment. From the 1970s to the present, tens of thousands of chemicals with applications in all aspects of our lives have grown more than 40-fold. Exposure to these new substances has impacted many aspects of our health, especially the delicate parts of the brain and nervous system. In parallel with the changes in our environment, we have seen the growth of brain disorders including Alzheimer’s Disease and autism in previously unimaginable ways. Here, Arnold Eiser elucidates some features of diseases affecting the nervous system that are increasing in incidence with a focus on those disorders that appear related to environmental toxins that modern life has introduced. He takes readers behind the scenes of the science itself to discover the human stories involved in the discovery and management of these illnesses. Offering insights from a variety of scientific disciplines, Eiser clearly and succinctly illustrates the impact of toxins on our brains and how we might better protect ourselves from negative outcomes. With interviews from leading authorities in the field of neuroscience, environmental toxicology, integrative medicine, neurology, immunology, geriatrics, and microbiology (re the gut microbiome), this book offers a robust understanding of the complex threats to our brains, and the healthy brain’s dependence upon many other systems within our bodies. This is a voyage of discovery into the science, history, and human struggle regarding disorders challenging the brain as well as their possible prevention.

Green Coffee Bean Extract in Human Health

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Author :
Publisher : CRC Press
ISBN 13 : 1315353989
Total Pages : 185 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Green Coffee Bean Extract in Human Health by : Debasis Bagchi

Download or read book Green Coffee Bean Extract in Human Health written by Debasis Bagchi and published by CRC Press. This book was released on 2016-08-05 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of green coffee bean (GCB) in human health is of emerging interest to the nutraceutical field, especially given its role in improving metabolic syndrome, including weight management, hypertension, diabetes, and neuroprotection. GCB extract contains a novel antioxidant known as chlorogenic acid (also caffeoylquinic acid), which has been shown to positively affect blood pressure, brain health, diabetes, and weight management. This book provides information on the diverse health benefits of green coffee bean extract, molecular mechanisms and signaling pathways, safety of GCB, dosage, and recommended usage. It focuses on the chemistry, biochemistry, pharmacology, and safety of GCB extract. GCB extract has brought a remarkable revolution in the nutraceutical marketplace. However, some controversies have been demonstrated recently. This book presents the state-of-the-art research studies from eminent scientists around the world on the potential and diversified health benefits of GCB extracts, with particular emphasis placed on the importance to standardize the appropriate extraction technology, quality control and assurance, and broad spectrum safety studies and human clinical studies to substantiate the regulatory claims and position the product in the marketplace.

Dietary Supplements

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Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Dietary Supplements by : United States. Federal Trade Commission. Bureau of Consumer Protection

Download or read book Dietary Supplements written by United States. Federal Trade Commission. Bureau of Consumer Protection and published by . This book was released on 1998 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fenugreek

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Author :
Publisher : CRC Press
ISBN 13 : 1000542890
Total Pages : 475 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Fenugreek by : Dilip Ghosh

Download or read book Fenugreek written by Dilip Ghosh and published by CRC Press. This book was released on 2022-05-29 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many centuries, fenugreek has been one of the most popular spices and vegetables serving as an integral part of culinary practices across many cultures. Fenugreek contains exceptional nutritional and medicinal properties, but scientific evidence for its potential health benefits has been considerably understudied and is beginning to grow. This book is a comprehensive compilation and documentation on the scientific profile of fenugreek and its phytoconstituents, including their most known applications and health benefits. It features a wide range of chapters written by highly experienced academics and industrial professionals. Topics cover applications of fenugreek including information on nutrition, fitness supplements, functional food, and excipients of novel drug delivery systems. In addition, it features topics on related products in the areas of nutraceuticals, functional food preparations, and complementary medicines. Features: · Comprehensive review of traditional wisdom and modern scientific evidence on fenugreek · Presents scientific evidence of fenugreek as an ingredient for product development formulation · Contains information on extraction methods, risk assessment, claim validations, and the regulatory status of fenugreek-based products · Covers broad physiological benefits of fenugreek in management of diabetes mellitus, primary hyperlipidemia, inflammation and pain, neuropathy and neuroinflammation, neurological and psychological disorders, kidney and lung disorders, as well as immunological, infectious, and malignant disorders · Enhances awareness of existing scientific knowledge surrounding fenugreek, whilst encouraging future scientific research towards better and safer nutritional and medicinal applications This book is a valuable resource of information on fenugreek for researchers, students, nutritionists, sport medicine practitioners, fitness enthusiasts and trainers, naturopaths, traditional practitioners, and toxicologists. This book helps industries in the fields of nutraceuticals, fitness and sports medicine products to develop their future products. However, this book is not a substitute for medical advice or recommendations.

The Nervous System, Third Edition

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Author :
Publisher : Infobase Holdings, Inc
ISBN 13 : 1646937228
Total Pages : 216 pages
Book Rating : 4.6/5 (469 download)

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Book Synopsis The Nervous System, Third Edition by : F. Evans-Martin

Download or read book The Nervous System, Third Edition written by F. Evans-Martin and published by Infobase Holdings, Inc. This book was released on 2022-01-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system allows us to move, feel, and think, and it is involved in nearly all of the functions of the human body. Nerves communicate signals between the brain and muscles, allowing us to move our hands and feet. Or, they relay messages about the environment through touch, taste, sight, and smell. Nerves can also communicate information about how we are feeling at any particular time and help to maintain homeostasis, or a stable state of equilibrium. The Nervous System, Third Edition discusses the development and organization of this diverse system, its functions, and potential injuries and complications. Packed with full-color photographs and illustrations, this absorbing book provides students with sufficient background information through references, websites, and a bibliography.

Gerontology

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 178923252X
Total Pages : 278 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Gerontology by : Grazia D’Onofrio

Download or read book Gerontology written by Grazia D’Onofrio and published by BoD – Books on Demand. This book was released on 2018-07-04 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging well and actively is the real objective of human being. This book is an up-to-date and realistic view on physiopathological mechanisms of aging and age-related diseases. The book includes topical contributions from multiple disciplines to support the fundamental goals of extending active life and enhancing its quality.

Chemically Modified Minds

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Author :
Publisher : Springer Nature
ISBN 13 : 9811567719
Total Pages : 189 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Chemically Modified Minds by : Matthew Hall

Download or read book Chemically Modified Minds written by Matthew Hall and published by Springer Nature. This book was released on 2020-10-30 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative edited collection brings together leading international academics to explore the use of various non-prescription and prescription substances. From a psychosocial perspective, the authors discuss the complex reasons behind their adoption, the ways in which they are misused, and links between use and cognitive enhancement. While studies on substance use to date have examined the aetiology and effects in the context of sporting performance, addiction and recreational use, there has been little work which explores their wider misuse to improve cognitive enhancement. With medical sociology and social psychology at its core, this important volume shows the complex reasons behind the misuse of various substances, how these are connected to contemporary desire for increased mental performance, and why the potential health risks and possibly harmful side effects do not act as deterrents.

Dietary Supplements in Health Promotion

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Author :
Publisher : CRC Press
ISBN 13 : 1498760309
Total Pages : 406 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Dietary Supplements in Health Promotion by : Taylor C. Wallace

Download or read book Dietary Supplements in Health Promotion written by Taylor C. Wallace and published by CRC Press. This book was released on 2015-05-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The supplement market continues to grow annually with more than half of the population using these products for reasons spanning from health maintenance to disease prevention and/or treatment. Dietary Supplements in Health Promotion presents clear and concise evidence on how dietary supplements may contribute to maintaining health status. The book