Progress in the Chemistry of Organic Natural Products 114

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Publisher : Springer Nature
ISBN 13 : 3030594440
Total Pages : 341 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 114 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 114 written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2021-04-01 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes current understandings and recent progress in four areas: in the first one, the cytochalasans, a group of fungal derived natural products characterized by a perhydro-isoindolone core fused with a macrocyclic ring are shown to exhibit high structural diversity and a broad spectrum of bioactivities. The second one is dedicated to a description of bioactive compounds from the medicinal plants of Myanmar, the third one is dedicated to new structure elucidation techniques in the field of sesquiterpenes. The last one discusses the endogenous natural products that are produced by human cells including endogenous amines, steroids, and fatty acid derived natural products. The co-metabolism and natural product production of the human microbiome is also described including tryptophan, bile acids, choline, and cysteine.

Progress in the Chemistry of Organic Natural Products 115

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Publisher : Springer Nature
ISBN 13 : 3030648532
Total Pages : 214 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 115 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 115 written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2021-04-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3709165296
Total Pages : 368 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products by :

Download or read book Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes of this classic series, now referred to simply as "Zechmeister” after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series’ inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Progress in the Chemistry of Organic Natural Products 99

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Publisher :
ISBN 13 : 9783319049014
Total Pages : 260 pages
Book Rating : 4.0/5 (49 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 99 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 99 written by A. Douglas Kinghorn and published by . This book was released on 2014-08-31 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783211833612
Total Pages : 286 pages
Book Rating : 4.8/5 (336 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products by : W. Herz

Download or read book Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products written by W. Herz and published by Springer Science & Business Media. This book was released on 2000-03-24 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783211830192
Total Pages : 180 pages
Book Rating : 4.8/5 (31 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products by : T. Fukai

Download or read book Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products written by T. Fukai and published by Springer Science & Business Media. This book was released on 1997-12-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Leguminosae is an economically important family in the Dicotyledonae with many cultivated species, e. g., beans and peas. The family also contains many well-known medicinal plants. It is composed of 17,000 or more species that constitute nearly one twelfth of the world's flowering plants (1). Traditionally the family has been divided into three subfamilies, Caesalpinioideae, Mimosoideae and Papilionoi deae, which are sometimes recognized as separate families Caesalpinia ceae, Mimosaceae and Papilionaceae. The International Code of Botanical Nomenclature permits alternative nomenclatures, the family names being replaced by Fabaceae, Fabales and Faboideae, and this usage will be common (2). Licorice (liquorice, kanzoh in Japanese, gancao in Chinese) is the name applied to the roots and stolons of some Glycyrrhiza species (Fabaceae) and has been used by human beings for at least 4000 years. The earliest written reference to the use of licorice is contained in the Codex Hammurabi dating from 2100 B. C., and the subsequent history in the West has been described in the earlier reviews (3-6). In the Far East, references to the effectiveness of licorice are contained in the "Shen Nong Ben Cao Jing," the first Chinese dispensatory whose original anonymous volumes probably appeared by the end of the third century (7, 8)."

Progress in the Chemistry of Organic Natural Products / Fortschritte der Chemie Organischer Naturstoffe / Progrès dans la Chimie des Substances Organiques Naturelles

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Publisher : Springer Science & Business Media
ISBN 13 : 370918164X
Total Pages : 362 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products / Fortschritte der Chemie Organischer Naturstoffe / Progrès dans la Chimie des Substances Organiques Naturelles by : P. R. Ashurst

Download or read book Progress in the Chemistry of Organic Natural Products / Fortschritte der Chemie Organischer Naturstoffe / Progrès dans la Chimie des Substances Organiques Naturelles written by P. R. Ashurst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mit Beiträgen zahlreicher Fachwissenschaftler

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783211828793
Total Pages : 354 pages
Book Rating : 4.8/5 (287 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products by : E. Fattorusso

Download or read book Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products written by E. Fattorusso and published by Springer Science & Business Media. This book was released on 1997-09-30 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes of this classic series, now referred to simply as "Zechmeister” after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series’ inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Progress in the Chemistry of Organic Natural Products 112

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Author :
Publisher : Springer Nature
ISBN 13 : 3030529665
Total Pages : 212 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 112 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 112 written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2020-12-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first chapter describes the oldest method of communication between living systems in Nature, the chemical language. Plants, due to their lack of mobility, have developed the most sophisticated way of chemical communication. Despite that many examples involve this chemical communication process - allelopathy, there is still a lack of information about specific allelochemicals released into the environment, their purpose, as well as in-depth studies on the chemistry underground. These findings are critical to gain a better understanding of the role of these compounds and open up a wide range of possibilities and applications, especially in agriculture and phytomedicine. The most relevant aspects regarding the chemical language of plants, namely, kind of allelochemicals have been investigated, as well as their releasing mechanisms and their purpose, are described in this chapter. The second chapter is focused on the natural products obtained from Hypericum L., a genus of the family Hypericaceae within the dicotyledones. Hypericum has been valued for its important biological and chemical properties and its use in the treatment of depression and as an antibacterial has been well documented in primary literature and ethnobotanical reports. The present contribution gives a comprehensive summary of the chemical constituents and biological effects of this genus. A comprehensive account of the chemical constituents including phloroglucinol derivatives, xanthones, dianthrones, and flavonoids is included. These compounds show a diverse range of biological activities that include antimicrobial, cytotoxic, antidepressant-like, and antinociceptive effects. The third chapter addresses microtubule stabilizers, which are a mainstay in the treatment of many solid cancers and are often used in combination with molecularly targeted anticancer agents and immunotherapeutics. The taccalonolides are a unique class of such microtubule stabilizers isolated from plants of Tacca species that circumvent clinically relevant mechanisms of drug resistance. Although initial reports suggested that the microtubule stabilizing activity of the taccalonolides is independent of direct tubulin binding, additional studies have found that potent C-22,23 epoxidated taccalonolides covalently bind the Aspartate 226 residue of β-tubulin and that this interaction is critical for their microtubule stabilizing activity. Some taccalonolides have demonstrated in vivo antitumor efficacy in drug-resistant tumor models with exquisite potency and long-lasting antitumor efficacy as a result of their irreversible target engagement. The recent identification of a site on the taccalonolide scaffold that is amenable to modification has provided evidence of the specificity of the taccalonolide-tubulin interaction and the opportunity to further optimize the targeted delivery of the taccalonolides to further improve their anticancer efficacy and potential for clinical development.

Progress in the Chemistry of Organic Natural Products 104

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Publisher : Springer
ISBN 13 : 3319456180
Total Pages : 246 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 104 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 104 written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-25 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.

Progress in the Chemistry of Organic Natural Products 113

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Publisher : Springer Nature
ISBN 13 : 3030530280
Total Pages : 247 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 113 by : A Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 113 written by A Douglas Kinghorn and published by Springer Nature. This book was released on 2021-04-16 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, chemical studies are described mainly from literature reports appearing since 2000, inclusive of investigations performed by the present authors, on the diversity in secondary metabolites of Ligularia growing in the Hengduan Mountains area of China, focusing on eremophilane sesquiterpenoids and other metabolites. More than 100 Ligularia species and their related genera in the plant family Senecioneae plants (Cremanthodium, Cacalia, Senecio, and others) grow in East Asia. For many years, researchers have studied the chemical constituents of these plants, and terpenoids, flavonoids, steroids, alkaloids, and aromatic compounds have been isolated. Among these, in particular, numerous sesquiterpenoids were reported. Within this book terpenoids and aromatic compounds (total 1049), both previously unknown and known, are presented. Finally, genetic studies and synthesis investigations are briefly reviewed.

Progress in the Chemistry of Organic Natural Products 111

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Publisher : Springer Nature
ISBN 13 : 3030378659
Total Pages : 158 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 111 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 111 written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2020-02-29 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first chapter in volume 111 summarizes research on the sesterterpenoids, which are known as a relatively small group of natural products. However, they express a variety of simple to complicated chemical structures. This chapter focuses on the chemical structures of sesterterpenoids and how their structures are synthesized in Nature. The second chapter is devoted to marine-derived fungi, which play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological activities that make them useful leads for drug discovery. Marine natural product research in China in general has made enormous progress in the last two decades as described in this chapter on fungal metabolites. This contribution covers 613 new natural products reported from 2001 to 2017 from marine-derived fungi obtained from algae, sponges, corals, and other marine organisms from Chinese waters.

Progress in the Chemistry of Organic Natural Products 102

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Publisher : Springer
ISBN 13 : 3319331728
Total Pages : 252 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products 102 by : A. Douglas Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 102 written by A. Douglas Kinghorn and published by Springer. This book was released on 2016-07-05 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its “reverse-pharmacology” focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.

Fortschritte Der Chemie Organischer Naturstoffe

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (797 download)

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Book Synopsis Fortschritte Der Chemie Organischer Naturstoffe by : H. Grisebach

Download or read book Fortschritte Der Chemie Organischer Naturstoffe written by H. Grisebach and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products 69

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3709165784
Total Pages : 279 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products 69 by :

Download or read book Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products 69 written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes of this classic series, now referred to simply as "Zechmeister” after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series’ inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Progress in the Chemistry of Organic Natural Products

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Publisher : Springer Science & Business Media
ISBN 13 : 3709168872
Total Pages : 508 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Progress in the Chemistry of Organic Natural Products by :

Download or read book Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this ASI was to bring together specialists in several complex variables (many of whom have contributed to complex potential theory) and specialists in potential theory (all of whom have contributed to several complex variables) together with young researchers and graduate students for an interchange of ideas and techniques. Not only was the status of current research presented, but also the relevant background, much of which is not yet available in books. The following topics and interconnections among them were discussed: 1. Real and Complex Potential Theory. Capacity and approximation, basic prop erties of plurisubharmonic functions and methods to manipulate their singularities and study their growth, Green functions, Chebyshev-type quadratures, electrostatic fields and potentials, propagation of smallness. 2. Complex Dynamics. Review of complex dynamics in one variable, Julia sets, Fatou sets, background in several variables, Henon maps, ergodicity, use of potential theory and multifunctions. 3. Banach Algebras and Infinite Dimensional Holomorphy. Analytic multi functions, spectral theory, analytic functions on a Banach space, semigroups of holomor phic isometries, Pick interpolation on uniform algebras and Von Neumann inequalities for operators on a Hilbert space. The basic notion of complex potential theory is that of a plurisubharmonic function.

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 88

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3211493891
Total Pages : 224 pages
Book Rating : 4.2/5 (114 download)

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Book Synopsis Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 88 by : W. Herz

Download or read book Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 88 written by W. Herz and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question.