Multiple Sclerosis

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Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Progress in Multiple Sclerosis Research

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Publisher : Springer Science & Business Media
ISBN 13 : 3642675549
Total Pages : 739 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Progress in Multiple Sclerosis Research by : H.J. Bauer

Download or read book Progress in Multiple Sclerosis Research written by H.J. Bauer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the annual meetings of the International Federation of Multiple Sclerosis Socie ties (IFMSS) the representatives of the national MS societies of numerous countries assemble for discussions and reports on work accomplished, under way, and to be undertaken in the future. In addition to publicity work, education, and patient ser vices, there has been an increasing interest in obtaining first hand, reliable, and re alistic information not only on the medical problems relevant to diagnosis, treat ment, and the management of MS, but also on progress in the difficult field of MS research. For this purpose the International Medical Advisory Board (IMAB) was founded. In the past years its members have organized a number of symposia in conjunc tion with the IFMSS meetings in New York, Copenhagen, Barcelona, Toronto, Am sterdam. The program of the G6ttingen symposium, relevant in its focus to the 1978 meeting of the IFMSS in Hannover, had the double purpose of bringing together scientists from many countries with active MS societies, and to inform the organi zers and members of these societies, and thereby also the MS patients, of problems and progress in a number of areas of MS research. The program was conceived as a survey of newer work undertaken in basic and experimental MS research and, on the clinical side, as a reassessment of the prerequisites in the diagnosis of MS, the value of laboratory tests, some therapeutic approaches, and organizational princi ples in the management of MS.

Progress in multiple sclerosis research

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Publisher :
ISBN 13 :
Total Pages : 55 pages
Book Rating : 4.:/5 (221 download)

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Book Synopsis Progress in multiple sclerosis research by :

Download or read book Progress in multiple sclerosis research written by and published by . This book was released on 1992 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Multiple Sclerosis Research

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Publisher : Nova Publishers
ISBN 13 : 9781594542848
Total Pages : 224 pages
Book Rating : 4.5/5 (428 download)

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Book Synopsis Progress in Multiple Sclerosis Research by : Frank H. Columbus

Download or read book Progress in Multiple Sclerosis Research written by Frank H. Columbus and published by Nova Publishers. This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a life-long chronic disease diagnosed primarily in young adults. During an MS attack, inflammation occurs in areas of the white matter of the central nervous system (nerve fibres that are the site of MS lesions) in random patches called plaques. This process is followed by destruction of myelin, which insulates nerve cell fibres in the brain and spinal cord. Myelin facilitates the smooth, high-speed transmission of electrochemical messages between the brain, the spinal cord, and the rest of the body. The initial symptom of MS is often blurred or double vision, red-green colour distortion, or even blindness in one eye. Most MS patients experience muscle weakness in their extremities and difficulty with co-ordination and balance. Most people with MS also exhibit paresthesias, transitory abnormal sensory feeling such as numbness or pins and needles. Some may experience pain or loss of feeling. About half of people with MS experience cognitive impairments such as difficulties with concentration, attention, memory, and judgement. This volume presents leading research from around the globe.

Advances in Multiple Sclerosis Research—Series I

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Publisher : MDPI
ISBN 13 : 3039439472
Total Pages : 334 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Advances in Multiple Sclerosis Research—Series I by : John Matsoukas

Download or read book Advances in Multiple Sclerosis Research—Series I written by John Matsoukas and published by MDPI. This book was released on 2021-04-19 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.

Multiple sclerosis

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Publisher :
ISBN 13 : 9780646109466
Total Pages : pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Multiple sclerosis by : International Federation of Multiple Sclerosis Societies

Download or read book Multiple sclerosis written by International Federation of Multiple Sclerosis Societies and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis Research Progress

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Publisher :
ISBN 13 : 9781604565706
Total Pages : 0 pages
Book Rating : 4.5/5 (657 download)

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Book Synopsis Multiple Sclerosis Research Progress by : Hanna Schwarz

Download or read book Multiple Sclerosis Research Progress written by Hanna Schwarz and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a life-long chronic disease diagnosed primarily in young adults. During an MS attack, inflammation occurs in areas of the white matter of the central nervous system (nerve fibres that are the site of MS lesions) in random patches called plaques. This process is followed by destruction of myelin, which insulates nerve cell fibres in the brain and spinal cord. Myelin facilitates the smooth, high-speed transmission of electrochemical messages between the brain, the spinal cord, and the rest of the body. The initial symptom of MS is often blurred or double vision, red-green colour distortion, or even blindness in one eye. Most MS patients experience muscle weakness in their extremities and difficulty with co-ordination and balance. Most people with MS also exhibit paresthesias, transitory abnormal sensory feeling such as numbness or "pins and needles." Some may experience pain or loss of feeling. About half of people with MS experience cognitive impairments such as difficulties with concentration, attention, memory, and judgement. This book presents leading research from around the globe.

Autoimmune Neurology

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Publisher : Elsevier
ISBN 13 : 0444634460
Total Pages : 568 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Autoimmune Neurology by :

Download or read book Autoimmune Neurology written by and published by Elsevier. This book was released on 2016-03-11 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Advances in Multiple Sclerosis

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Publisher : CRC Press
ISBN 13 : 9781853178719
Total Pages : 236 pages
Book Rating : 4.1/5 (787 download)

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Book Synopsis Advances in Multiple Sclerosis by : Sten Fredrikson

Download or read book Advances in Multiple Sclerosis written by Sten Fredrikson and published by CRC Press. This book was released on 1999-09-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looking at the lastest advances in research into multiple sclerosis, from genetics to the use of magnetic resonance imaging and the organization of MS care.

Progress in Multiple Sclerosis: Research and Treatment

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Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Progress in Multiple Sclerosis: Research and Treatment by : Uri Leibowitz

Download or read book Progress in Multiple Sclerosis: Research and Treatment written by Uri Leibowitz and published by . This book was released on 1972 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis

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Publisher : Demos Medical Publishing
ISBN 13 : 9781934559277
Total Pages : 264 pages
Book Rating : 4.5/5 (592 download)

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Book Synopsis Multiple Sclerosis by : Dr. T. Jock Murray, MS

Download or read book Multiple Sclerosis written by Dr. T. Jock Murray, MS and published by Demos Medical Publishing. This book was released on 2004-12-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis: The History of a Disease won a 2005 ForeWord Book of the Year Silver Medal! The basic facts about multiple sclerosis are well known: it is the most common neurologic disease of young adults, usually beginning with episodic attacks of neurologic symptoms, then entering a progressive phase some years later. Its onset has an average age of 30, and occurs in about 1 in 500 individuals of European ancestry living primarily in temperate climates. There appears to be a complex interaction between a genetic predisposition and an environmental trigger that initiates the disease. But these facts do not convey the impact of the disease on the people whose lives it affects. In this elegantly written and comprehensive history, we meet individuals who suffered with MS in the centuries before the disease had a name, including blessed Lidwina of Holland, who took joy from her misery, believing that she was sent to accept suffering for the sins of others; Augustus d'Est, grandson of George III and cousin of Queen Victoria, whose case shows how someone with access to the best of medical care of the age was understood and managed; and Heinrich Heine, the great German poet, who also had access to all medical services that were available, but who progressed into his mattress grave in two decades, aware of the loss of physical ability while still able to compose great poetry to the end. From these early cases the author demonstrates how progress in diagnosing and managing multiple sclerosis has paralleled the development of medical science, from the early developments in modern studies of anatomy and pathology, to the framing of the disease in the nineteenth century, and eventually to modern diagnosis and treatment. From beginning to end, Dr. Murray takes us on a fascinating journey of discovery, in the process showing how the evolution of our understanding of multiple sclerosis has been part of the greater history of medical knowledge.

Multiple Sclerosis

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Publisher : Springer Science & Business Media
ISBN 13 : 1447112717
Total Pages : 388 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Multiple Sclerosis by : Donald E. Goodkin

Download or read book Multiple Sclerosis written by Donald E. Goodkin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the therapeutic developments in clinical trial design that have resulted in new treatment options for patients suffering from MS. Important ethical considerations that arise with the new treatments are included, as well as the perspective on the emergence of MS as a treatable disease.

Translational Methods for Multiple Sclerosis Research

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Publisher : Humana
ISBN 13 : 9781071612125
Total Pages : 335 pages
Book Rating : 4.6/5 (121 download)

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Book Synopsis Translational Methods for Multiple Sclerosis Research by : Sergiu Groppa

Download or read book Translational Methods for Multiple Sclerosis Research written by Sergiu Groppa and published by Humana. This book was released on 2021-08-03 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

Multiple Sclerosis

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Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Multiple Sclerosis by :

Download or read book Multiple Sclerosis written by and published by . This book was released on 1996 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurobehavioral Aspects of Multiple Sclerosis

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Publisher : Oxford University Press, USA
ISBN 13 : 9780195054002
Total Pages : 300 pages
Book Rating : 4.0/5 (54 download)

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Book Synopsis Neurobehavioral Aspects of Multiple Sclerosis by : Stephen M. Rao

Download or read book Neurobehavioral Aspects of Multiple Sclerosis written by Stephen M. Rao and published by Oxford University Press, USA. This book was released on 1990 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is the most common neurological disease affecting young and middle-aged adults, and while much is known about its classic motor and sensory symptoms, it has only been during the past decade, with the advent of specialized neuropsychological test procedures and brain imaging methods, that the cognitive and behavioral changes associated with the disorder have come to be better understood. This book charts that recent progress. It provides a balanced, interdisciplinary view, covering the prevalence, range, type, and course of cognitive and affective disturbances in multiple sclerosis; the interrelationship of the neurobehavioral disturbance with brain abnormalities as visualized by neuroimaging; and the impact of cognitive and behavioral disabilities on patient rehabilitation. The book will be of value to all physicians and psychologists who deal with MS patients. It will update their knowledge of the disease and its ramifications, and will help in communicating this information to patients and their families.

Primary Progressive Multiple Sclerosis

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Publisher : Springer Science & Business Media
ISBN 13 : 8847022347
Total Pages : 188 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Primary Progressive Multiple Sclerosis by : M. Filippi

Download or read book Primary Progressive Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. " Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin ical trials have excluded PPMS patients on two counts. Clinical worsening devel ops slowly in PPMS and may not be recognized during the course of a 2-or 3-year trial even in untreated control patients. This factor alone adds to the potential for a type 2 error or, at the very least, inflates the sample size and duration of the trial. In addition, there is mounting evidence that progressive axonal degeneration and neuronal loss (rather than active, recurrent inflammation) may be important components of the pathology in this form of the disease. Although contemporary trials are evaluating whether PPMS patients may benefit from treatment with the ~-interferons and glatiramer acetate, preliminary, uncontrolled clinical experi ence suggests that the results may not be dramatic.

Multiple Sclerosis

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Multiple Sclerosis by :

Download or read book Multiple Sclerosis written by and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: