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Programming The Hpa Axis By Early Life Experience
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Book Synopsis Programming HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation by : Rachel Yehuda
Download or read book Programming HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation written by Rachel Yehuda and published by Frontiers Media SA. This book was released on 2015-03-16 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
Book Synopsis Programming the HPA-axis by Early Life Experience by :
Download or read book Programming the HPA-axis by Early Life Experience written by and published by . This book was released on 2015 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Functional Somatic Symptoms in Children and Adolescents by : Kasia Kozlowska
Download or read book Functional Somatic Symptoms in Children and Adolescents written by Kasia Kozlowska and published by Springer Nature. This book was released on 2020-09-30 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.
Book Synopsis The Hypothalamus-Pituitary-Adrenal Axis by :
Download or read book The Hypothalamus-Pituitary-Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later
Book Synopsis Perinatal Inflammation and Adult Psychopathology by : Antonio L. Teixeira
Download or read book Perinatal Inflammation and Adult Psychopathology written by Antonio L. Teixeira and published by Springer Nature. This book was released on 2020-04-07 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.
Book Synopsis Anxiety Disorders by : Kerry Ressler
Download or read book Anxiety Disorders written by Kerry Ressler and published by Oxford University Press. This book was released on 2015-04-15 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anxiety affects millions, manifesting as generalized anxiety disorder (GAD), obsessive compulsive disorder, panic disorder, phobias, post-traumatic-stress disorder (PTSD), and social anxiety disorder. Not only are anxiety disorders common, but they are also crippling, frequently co-occurring and predict high risk for depressive disorders. Shared mechanisms may explain the overlapping features of many anxiety disorders and account for associations with other highly-impairing conditions, such as major depression and substance use. Beyond risk for specific disorders, anxiety also predicts a number of other adverse outcomes, including suicidal behavior, medical problems, social, and economic difficulties. Conversely, disorder-specific mechanisms may also exist and explain the unique features of each syndrome. Thus, it is important to understand both shared and specific aspects of anxiety. The Primer on Anxiety Disorders provides early-stage practitioners and trainees, as well as seasoned clinicians and researchers, with need-to-know knowledge on diagnosis and treatment. Clinical cases are used throughout the book to enhance understanding of and illustrate specific disorders, comorbid conditions and clinical issues. To facilitate an integrative approach, content allows clinicians to understand patient characteristics and tailor interventions. The integrated approach of each chapter includes recent research on genetics and neuroscience to understand the mechanisms of anxiety disorders, focusing on the forthcoming new nosology in DSM-5. Chapters further integrate innovative advances in clinical research providing research on a range of discoveries regarding biomarkers of illness, biological predictors of treatments and the effect of treatment on neurocircuitry.
Book Synopsis Environmental Experience and Plasticity of the Developing Brain by : Alessandro Sale
Download or read book Environmental Experience and Plasticity of the Developing Brain written by Alessandro Sale and published by John Wiley & Sons. This book was released on 2016-02-04 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Experience and Plasticity of the Developing Brain goes beyond the genetic basis of neurodevelopment. Chapters illuminate the external factors that can dramatically impact the brain early in life and, consequently, the eventual accomplishment of developmental milestones and the construction of adult behavior and personality. Authored and edited by leaders in this rapidly growing field, Environmental Experience and Plasticity of the Developing Brain not only surveys preexisting literature on the effects of environment versus genetics, but also discusses more recent studies on the impacts of neurodevelopment in terms of maternal stimulation, environmental enrichment and sensory deprivation. The book also includes key examples of environmental impacts on preexisting genetic syndromes leading to developmental disabilities. Focus is also given to the consequences of early adverse experience in primates, as well as neurobiological and behavioral consequences in institutionalized human children and the reversibility of such consequences. Environmental Experience and Plasticity of the Developing Brain encompasses a broad area of research in the field of developmental neurobiology and offers a unique combination of different examples of environmental factors affecting brain development and behavior.
Book Synopsis ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology by : Nicole Gallo-Payet
Download or read book ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology written by Nicole Gallo-Payet and published by Frontiers Media SA. This book was released on 2017-07-27 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.
Download or read book Anxiety Disorders written by Yong-Ku Kim and published by Springer. This book was released on 2020-02-17 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews all important aspects of anxiety disorders with the aim of shedding new light on these disorders through combined understanding of traditional and novel paradigms. The book is divided into five sections, the first of which reinterprets anxiety from a network science perspective, examining the altered topological properties of brain networks in anxiety disorders. The second section discusses recent advances in understanding of the neurobiology of anxiety disorders, covering, for example, gene-environmental interactions and the roles of neurotransmitter systems and the oxytocin system. A wide range of diagnostic and clinical issues in anxiety disorders are then addressed, before turning attention to contemporary treatment approaches in the context of novel bio-psychosocial-behavioral models, including bio- and neurofeedback, cognitive behavioral therapy, neurostimulation, virtual reality exposure therapy, pharmacological interventions, psychodynamic therapy, and CAM options. The final section is devoted to precision psychiatry in anxiety disorders, an increasingly important area as we move toward personalized treatment. Anxiety Disorders will be of interest for all researchers and clinicians in the field.
Book Synopsis Behavioral Neurobiology of Stress-related Disorders by : Carmine M. Pariante
Download or read book Behavioral Neurobiology of Stress-related Disorders written by Carmine M. Pariante and published by Springer. This book was released on 2014-11-11 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress is such an over-used word that it is at time difficult to define its core features. When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels. Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects. The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress. Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior.
Book Synopsis Understanding Depression by : Yong-Ku Kim
Download or read book Understanding Depression written by Yong-Ku Kim and published by Springer. This book was released on 2018-01-02 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological issues. Detailed information is presented on a wide range of topics, including genetics, molecular and cellular biology, and aspects at the neural circuit and multicellular system levels. Readers will gain a deeper appreciation of the factors and interactions underlying individual variation in responsiveness to stress and vulnerability to depression, as well as a clear understanding of potential treatment targets and causes of treatment resistance based on the latest research. A concluding section considers progress towards precision psychiatry and gender and cultural differences in depression. The companion volume is dedicated to clinical and management issues in depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.
Book Synopsis Child Psychology by : Lawrence Balter
Download or read book Child Psychology written by Lawrence Balter and published by Psychology Press. This book was released on 2016-02-26 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of Child Psychology continues the tradition of showcasing cutting-edge research in the field of developmental science, including individual differences, dynamic systems and processes, and contexts of development. While retaining a similar structure to the last edition, this revision consists of completely new content with updated programmatic research and contemporary research trends and interests. The first three sections highlight research that is organized chronologically by age: Infancy, Childhood, and Adolescence. Within each section, individual chapters address contemporary research on a specific area of development, such as learning, cognition, social, and emotional development at that period in childhood. The fourth section, Ecological Influences, emphasizes contextual influences relevant to children of all ages, including risk and protective processes, family and neighborhood context, race and ethnicity, peer relations, the effects of poverty, and the impact of the digital world. Child Psychology also features a unique focus on four progressive themes. First, emphasis is placed on theory and explanation—the "why and how" of the developmental process. Second, explanations of a transactional and multidimensional nature of development are at the forefront of all chapters. Third, the multi-faceted approach to development highlights contextual influences and cultural diversity among children from different communities and backgrounds. Finally, methodological innovation is a key concern, and research tools presented across chapters span the full array available to developmental scientists who focus on different systems and levels of analysis. The thoroughness and depth of this book, in addition to its methodological rigor, make it an ideal handbook for researchers, practitioners, policy makers, and advanced students across a range of disciplines, including psychology, education, economics and public policy.
Book Synopsis Fetal Alcohol Spectrum Disorder by : Edward P. Riley
Download or read book Fetal Alcohol Spectrum Disorder written by Edward P. Riley and published by John Wiley & Sons. This book was released on 2011-04-27 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the recent increased public awareness of the topic, this is the first and most comprehensive resource for over a decade on the molecular basis, prevalence, treatment options, socioeconomic impact and prevention strategies of FADS. Edited by world-renowned experts, this compendium includes the latest research results to provide new insights and realistic estimations of FADS frequencies in Western communities. An invaluable resource for every professional dealing with the diagnosis, prevention and treatment of FADS, from researchers via health professionals to social workers.
Book Synopsis Developmental Psychopathology, Volume 2 by : Dante Cicchetti
Download or read book Developmental Psychopathology, Volume 2 written by Dante Cicchetti and published by John Wiley & Sons. This book was released on 2006-03-31 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Psychopathology, Second Edition, contains in three volumes the most complete and current research on every aspect of developmental psychopathology. This seminal reference work features contributions from national and international expert researchers and clinicians who bring together an array of interdisciplinary work to ascertain how multiple levels of analysis may influence individual differences, the continuity or discontinuity of patterns and the pathways by which the same developmental outcomes may be achieved. This volume addresses theoretical perspectives and methodological.
Book Synopsis Why Zebras Don't Get Ulcers by : Robert M. Sapolsky
Download or read book Why Zebras Don't Get Ulcers written by Robert M. Sapolsky and published by Holt Paperbacks. This book was released on 2004-09-15 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renowned primatologist Robert Sapolsky offers a completely revised and updated edition of his most popular work, with over 225,000 copies in print Now in a third edition, Robert M. Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress. As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear-and the ones that plague us now-are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way-through fighting or fleeing. Over time, this activation of a stress response makes us literally sick. Combining cutting-edge research with a healthy dose of good humor and practical advice, Why Zebras Don't Get Ulcers explains how prolonged stress causes or intensifies a range of physical and mental afflictions, including depression, ulcers, colitis, heart disease, and more. It also provides essential guidance to controlling our stress responses. This new edition promises to be the most comprehensive and engaging one yet.
Book Synopsis Soothing and Stress by : Michael Lewis
Download or read book Soothing and Stress written by Michael Lewis and published by Psychology Press. This book was released on 1999-04 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this volume, all leaders in research on stress and coping from a developmental perspectives, examine behavioral and physiological correlates of stress and soothing for infants. For researchers, clinicians, and pediatric specialists.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309493382 Total Pages :621 pages Book Rating :4.3/5 (94 download)
Book Synopsis Vibrant and Healthy Kids by : National Academies of Sciences, Engineering, and Medicine
Download or read book Vibrant and Healthy Kids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-27 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.
