Processing And Characterization Of Polymer Microparticles For Controlled Drug Delivery Systems

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Processing and Characterization of Polymer Microparticles for Controlled Drug Delivery Systems

Author : Aravind Chakrapani
Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.:/5 (123 download)

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Book Synopsis Processing and Characterization of Polymer Microparticles for Controlled Drug Delivery Systems by : Aravind Chakrapani

Download or read book Processing and Characterization of Polymer Microparticles for Controlled Drug Delivery Systems written by Aravind Chakrapani and published by . This book was released on 2006 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: We report a novel soft lithography based technique to fabricate non-spherical biodegradable polymeric microparticles of different sizes and shapes as drug delivery systems. Geometrical control over the shape and size of these microparticles renders them different aerodynamic and fluidic dynamic properties when compared to conventional spherical microparticles and may prove to be beneficial in certain drug delivery strategies, such as pulmonary and intravenous routes. The surface morphology of the particles was studied using a scanning electron microscope and size distribution of the particles was determined using a Coulter counter. The process is reproducible and millions of uniform biodegradable particles of various sizes and shapes with dimensions ranging from 2-30 um have been fabricated and were collected by a simple vacuum filtration apparatus. In addition, we demonstrated encapsulation of a model drug (FITC), and FITC distributions within the particles were studied by confocal microscopy. Particle size is a critical parameter for several aspects of controlled drug delivery including control of drug-release kinetics, passive targeting to specific cell or tissue types, biodistribution upon administration and available routes of administration. In conclusion, the uniform, biodegradable polymeric microparticles produced have potential to be used in a variety of drug delivery applications and polymer-based microfabrication technology holds promise to produce sophisticated, multi-functional drug delivery devices.

Polymers for Controlled Drug Delivery

Author : Peter J. Tarcha
Publisher : CRC Press
ISBN 13 : 9780849356520
Total Pages : 300 pages
Book Rating : 4.3/5 (565 download)

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Book Synopsis Polymers for Controlled Drug Delivery by : Peter J. Tarcha

Download or read book Polymers for Controlled Drug Delivery written by Peter J. Tarcha and published by CRC Press. This book was released on 1990-11-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.7/5 (253 download)

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Book Synopsis Polymeric Drug Delivery Systems by : Glen S. Kwon

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Polymers for Controlled Drug Delivery

Author : Peter J. Tarcha
Publisher : CRC Press
ISBN 13 : 1000941116
Total Pages : 298 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Polymers for Controlled Drug Delivery by : Peter J. Tarcha

Download or read book Polymers for Controlled Drug Delivery written by Peter J. Tarcha and published by CRC Press. This book was released on 2023-06-14 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.

A Novel Approach For Controlled Drug Delivery - Microparticles

Author : Shrujal Patel
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783659124488
Total Pages : 108 pages
Book Rating : 4.1/5 (244 download)

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Book Synopsis A Novel Approach For Controlled Drug Delivery - Microparticles by : Shrujal Patel

Download or read book A Novel Approach For Controlled Drug Delivery - Microparticles written by Shrujal Patel and published by LAP Lambert Academic Publishing. This book was released on 2012 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microparticles are one of the key novel drug delivery systems has been widely used to precisely modulate release rate. Microparticles based polymeric systems fabricated using suitable carrier has been extensively explored as an effective matrix for controlled and sustained release delivery of many drugs. With the controlled release systems, the rate of drug release matches the rate of drug elimination, and therefore the drug concentration is within the therapeutic window for the majority of the 24-hr period.The aim of this study was to prepare Eudragit microspheres containing Tramadol HCl by solvent evaporation method to achieve a controlled drug release profile. Investigation of the effect of various processing and formulation factors such as polymer type, drug: polymer ratio, stirring speed to obtain spherical particles. Then yield of production, shape, and mean particle size, particle size distribution, encapsulation efficiency, surface properties and release rate of drug from the microspheres were performed.

Polymer Blends for Drug Release Systems

Author : Nafisa Gull
Publisher : Frontiers Media SA
ISBN 13 : 2832508057
Total Pages : 100 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Polymer Blends for Drug Release Systems by : Nafisa Gull

Download or read book Polymer Blends for Drug Release Systems written by Nafisa Gull and published by Frontiers Media SA. This book was released on 2023-03-17 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery Systems in Cancer Therapy

Author : Dennis M. Brown
Publisher : Springer Science & Business Media
ISBN 13 : 1592594271
Total Pages : 438 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Drug Delivery Systems in Cancer Therapy by : Dennis M. Brown

Download or read book Drug Delivery Systems in Cancer Therapy written by Dennis M. Brown and published by Springer Science & Business Media. This book was released on 2003-09-08 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Polymers in Controlled Drug Delivery

Author : Lisbeth Illum
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Polymers in Controlled Drug Delivery by : Lisbeth Illum

Download or read book Polymers in Controlled Drug Delivery written by Lisbeth Illum and published by Butterworth-Heinemann. This book was released on 1987 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymeric Drugs and Drug Delivery Systems

Author : Raphael M. Ottenbrite
Publisher : CRC Press
ISBN 13 : 1420010255
Total Pages : 328 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Polymeric Drugs and Drug Delivery Systems by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs and Drug Delivery Systems written by Raphael M. Ottenbrite and published by CRC Press. This book was released on 2019-04-30 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Drug Delivery Systems Based on Polymer Blends

Author : Xinyin Liu
Publisher :
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.:/5 (532 download)

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Book Synopsis Drug Delivery Systems Based on Polymer Blends by : Xinyin Liu

Download or read book Drug Delivery Systems Based on Polymer Blends written by Xinyin Liu and published by . This book was released on 2003 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceutical Applications of Polymers for Drug Delivery

Author : David Jones
Publisher : iSmithers Rapra Publishing
ISBN 13 : 9781859574799
Total Pages : 138 pages
Book Rating : 4.5/5 (747 download)

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Book Synopsis Pharmaceutical Applications of Polymers for Drug Delivery by : David Jones

Download or read book Pharmaceutical Applications of Polymers for Drug Delivery written by David Jones and published by iSmithers Rapra Publishing. This book was released on 2004 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The review focuses on the use of pharmaceutical polymer for controlled drug delivery applications. Examples of pharmaceutical polymers and the principles of controlled drug delivery are outlined and applications of polymers for controlled drug delivery are described. The field of controlled drug delivery is vast therefore this review aims to provide an overview of the applications of pharmaceutical polymers. The review is accompanied by approximately 250 abstracts taken from papers and books in the Rapra Polymer Library database, to facilitate further reading on this subject.

Handbook of Ultrasonics and Sonochemistry

Author : Muthupandian Ashokkumar
Publisher :
ISBN 13 : 9789812874702
Total Pages : pages
Book Rating : 4.8/5 (747 download)

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Book Synopsis Handbook of Ultrasonics and Sonochemistry by : Muthupandian Ashokkumar

Download or read book Handbook of Ultrasonics and Sonochemistry written by Muthupandian Ashokkumar and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Applications of Polymers in Drug Delivery by : Ambikanandan Misra

Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. - Explains how polymers can be prepared and utilized for all major drug delivery routes - Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics - Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Polymers in Drug Delivery

Author : Ijeoma F. Uchegbu
Publisher : CRC Press
ISBN 13 : 1000611248
Total Pages : 426 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Polymers in Drug Delivery by : Ijeoma F. Uchegbu

Download or read book Polymers in Drug Delivery written by Ijeoma F. Uchegbu and published by CRC Press. This book was released on 2006-05-19 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together, the nano explosion and the genomic revolution are ushering in a new frontier in drug delivery. In recent years we've seen how polymers can play a crucial role in controlling the rate of drug release, enhancing solubility and uptake, and limiting degradation and toxicity. In the very near future, they may well be used to deliver gene thera

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author : Jorge Coelho
Publisher : Springer Science & Business Media
ISBN 13 : 9400760108
Total Pages : 433 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by : Jorge Coelho

Download or read book Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment written by Jorge Coelho and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Polymeric Site-specific Pharmacotherapy

Author : A. J. Domb
Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Polymeric Site-specific Pharmacotherapy by : A. J. Domb

Download or read book Polymeric Site-specific Pharmacotherapy written by A. J. Domb and published by . This book was released on 1994-07-26 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Site-Specific Pharmacotherapy Edited by A. J. Domb The Hebrew University of Jerusalem, Israel This unique edited volume provides a comprehensive overview of site-specific drug delivery using polymeric implant devices. From the basic concept of localized drug delivery to major applications under active research, the subject is treated from a theoretical and practical viewpoint. Coverage includes the design, development and applications of polymeric devices, including suitable polymers, delivery systems and mechanisms of drug release. Recent advances and ongoing research are included and many subjects are reviewed here for the first time. Contributed to by an international team of acknowledged experts, this volume will have broad appeal amongst researchers, both in academia and industry, with an interest in polymer chemistry, biopolymers, pharmaceutical analysis, pharmacology, bioengineering, and medical and organic chemistry. Contents include: Implantable Biodegradable Polymers for Site-specific Drug Delivery A. J. Domb; Drug Release and Tissue Distribution from a Polymer Implant M. L. Radomsky; Modelling of Drug Delivery to Brain Tissue G. D. Lapin; Polymer Conjugated Macromolecular Drugs for Tumor Specific Targeting H. Maeda; Drug Delivery to the Brain H. Brem, K. A. Walter, R. J. Tamargo, A. Olivi and R. Langer; Microparticulate Systems for Site-specific Therapy — Bone Marrow Targeting C. J. Porter, M. C. Davies, S. S. Davies and L. Illum; Drug Delivery to the Lung K. C. Meyer, W. Auerbach and R. Auerbach; Polymers for the Prevention of Surgical Adhesions A. J. Domb and D. Wiseman

Synthesis and Characterization of Disperse Nanostructured Polymer Microparticles Via Microemulsion Polymerization for Potential Drug Delivery

Download Synthesis and Characterization of Disperse Nanostructured Polymer Microparticles Via Microemulsion Polymerization for Potential Drug Delivery PDF Online Free

Author : R. T. Vickerman
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Synthesis and Characterization of Disperse Nanostructured Polymer Microparticles Via Microemulsion Polymerization for Potential Drug Delivery by : R. T. Vickerman

Download or read book Synthesis and Characterization of Disperse Nanostructured Polymer Microparticles Via Microemulsion Polymerization for Potential Drug Delivery written by R. T. Vickerman and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: