Drug Delivery Systems In Cancer Therapy

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Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 572 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advanced Drug Delivery Systems in the Management of Cancer by : Kamal Dua

Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Drug Delivery Systems in Cancer Therapy

Author : Dennis M. Brown
Publisher : Springer Science & Business Media
ISBN 13 : 1592594271
Total Pages : 596 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Drug Delivery Systems in Cancer Therapy by : Dennis M. Brown

Download or read book Drug Delivery Systems in Cancer Therapy written by Dennis M. Brown and published by Springer Science & Business Media. This book was released on 2003-09-08 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128163674
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by : Prashant Kesharwani

Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-01-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Nanoparticle Drug Delivery Systems for Cancer Treatment

Author : Hala Gali-Muhtasib
Publisher : CRC Press
ISBN 13 : 1000681416
Total Pages : 179 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanoparticle Drug Delivery Systems for Cancer Treatment by : Hala Gali-Muhtasib

Download or read book Nanoparticle Drug Delivery Systems for Cancer Treatment written by Hala Gali-Muhtasib and published by CRC Press. This book was released on 2020-02-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Nano Drug Delivery Strategies for the Treatment of Cancers

Author : Awesh K. Yadav
Publisher : Academic Press
ISBN 13 : 0128197943
Total Pages : 374 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nano Drug Delivery Strategies for the Treatment of Cancers by : Awesh K. Yadav

Download or read book Nano Drug Delivery Strategies for the Treatment of Cancers written by Awesh K. Yadav and published by Academic Press. This book was released on 2020-09-03 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128173319
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics by : Prashant Kesharwani

Download or read book Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-06-25 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Nanoparticle Drug Delivery Systems for Cancer Treatment

Author : Hala Gali-Muhtasib
Publisher : CRC Press
ISBN 13 : 1000680878
Total Pages : 342 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanoparticle Drug Delivery Systems for Cancer Treatment by : Hala Gali-Muhtasib

Download or read book Nanoparticle Drug Delivery Systems for Cancer Treatment written by Hala Gali-Muhtasib and published by CRC Press. This book was released on 2020-02-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128136901
Total Pages : 836 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug Targeting and Stimuli Sensitive Drug Delivery Systems by : Alexandru Mihai Grumezescu

Download or read book Drug Targeting and Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-21 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Drug Delivery Systems

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
ISBN 13 : 1588298914
Total Pages : 255 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Drug Delivery Systems by : Kewal K. Jain

Download or read book Drug Delivery Systems written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.

Silk-based Drug Delivery Systems

Author : Elia Bari
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017722
Total Pages : 243 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Silk-based Drug Delivery Systems by : Elia Bari

Download or read book Silk-based Drug Delivery Systems written by Elia Bari and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Drug Delivery in Oncology

Author : Felix Kratz
Publisher : John Wiley & Sons
ISBN 13 : 3527647759
Total Pages : 1828 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Drug Delivery in Oncology by : Felix Kratz

Download or read book Drug Delivery in Oncology written by Felix Kratz and published by John Wiley & Sons. This book was released on 2013-09-30 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Cancer Drug Delivery Systems Based on the Tumor Microenvironment

Author : Yasuhiro Matsumura
Publisher : Springer Nature
ISBN 13 : 4431568808
Total Pages : 325 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Cancer Drug Delivery Systems Based on the Tumor Microenvironment by : Yasuhiro Matsumura

Download or read book Cancer Drug Delivery Systems Based on the Tumor Microenvironment written by Yasuhiro Matsumura and published by Springer Nature. This book was released on 2020-01-07 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophysiology and pharmacology may be leading the development of antitumor drugs in the wrong direction and wasting a lot of money. Although there have been numerous reports of genetic and phenotypic changes in tumors, a large body of pathological and clinical evidence supports the conclusion that there are no pivotal changes in tumor cells that distinguish them consistently and reliably from normal dividing cells. Unlike using antibiotics against bacterial infection, therefore, anticancer agents (ACAs) need to be delivered selectively to tumor tissues and should be kept there long enough to reproduce the concentrations they reach in the Petri dish, which is a closed space where the cytocidal effects of any anticancer agents (ACAs) including molecular targeting agents are very strong. In the body, however, administered ACAs are cleared with the passage of time. Furthermore, most human cancers possess abundant stroma that hinders the penetration of drugs into the tumor microenvironment. Therefore, to overcome these difficulties, novel drug delivery systems have been designed, such as nanoparticles and ACA conjugated antibodies to stromal components and to cancer cell surface antigens. These advances are described in this book after the first section, which describes core features of the pathophysiology of the cancer microenvironment, on which these new developments are based.

Nanopharmaceutical Advanced Delivery Systems

Author : Vivek Dave
Publisher : John Wiley & Sons
ISBN 13 : 1119711681
Total Pages : 467 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Nanopharmaceutical Advanced Delivery Systems by : Vivek Dave

Download or read book Nanopharmaceutical Advanced Delivery Systems written by Vivek Dave and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Handbook of Research on Advancements in Cancer Therapeutics

Author : Kumar, Sumit
Publisher : IGI Global
ISBN 13 : 1799865312
Total Pages : 913 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Handbook of Research on Advancements in Cancer Therapeutics by : Kumar, Sumit

Download or read book Handbook of Research on Advancements in Cancer Therapeutics written by Kumar, Sumit and published by IGI Global. This book was released on 2020-11-27 with total page 913 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity of cancer demands an integrated approach from both a cancer biology standpoint and a pharmaceutical basis to understand the different anticancer modalities. Current research has been focused on conventional and newer anticancer modalities, recent discoveries in cancer research, and also the advancements in cancer treatment. There is a current need for more research on the advances in cancer therapeutics that bridge the gap between basic research (pharmaceutical drug development processes, regulatory issues, and translational experimentation) and clinical application. Recent promising discoveries such as immunotherapies, promising therapies undergoing clinical trials, synthetic lethality, carbon beam radiation, and other exciting targeted therapies are being studied to improve and advance the studies of modern cancer treatment. The Handbook of Research on Advancements in Cancer Therapeutics serves as a comprehensive guide in modern cancer treatment by combining and merging the knowledge from both cancer biology and the pharmacology of anticancer modalities. The chapters come from multi-disciplinary backgrounds, including scientists and clinicians from both academia and various industries, to discuss nascent personalized therapies and big data-driven cancer treatment. While highlighting topic areas that include cancer prevention, cancer therapeutics, and cancer treatments through the lenses of technology, medicine/drugs, and alternate therapies, this book is ideally intended for oncologists, radiation oncologists, surgical oncologists, and cancer biologists, along with practitioners, stakeholders, researchers, academicians, and students who are interested in understanding the most fundamental aspects of cancer and the available therapeutic opportunities.

Liposome-Based Drug Delivery Systems

Author : Wan-Liang Lu
Publisher : Springer
ISBN 13 : 9783662493182
Total Pages : 0 pages
Book Rating : 4.4/5 (931 download)

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Book Synopsis Liposome-Based Drug Delivery Systems by : Wan-Liang Lu

Download or read book Liposome-Based Drug Delivery Systems written by Wan-Liang Lu and published by Springer. This book was released on 2021-07-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the protocols for fabrication of liposomal drug delivery system, and consists of two parts. The first part emphasizes the basic protocols and concepts for fabrication of drug-loaded liposomes. For new investigators, laying the groundwork is the first step. This part focuses on the fabrication details in liposomes formulations, which are the so-called small tricks while usually not disclosed in mostly published research articles. However, these processing details are crucial for the preparation of liposomes. And the second part focuses on the strategies in modified and/or functionalized liposomes to adapt to pathophysiological environment, as well as their application in treating diseases. As new analytical and synthetic technologies become available, and improved understanding of pathophysiology, various functionalized drug liposomes are developing to fit the requirements of different therapeutic purposes, exhibiting a broad range of applications. Accordingly, the objectives of this part are aimed at deeply unearthing the formulation of drug-loaded liposomes, describing the detailed operation of liposomal formulation, and further demonstrating their potential applications. Therefore, this volume shows the features of experimental report or protocol for proving a guide to scientists, research students, and young investigators in pharmaceutical enterprises.

Nanoparticle-Based Drug Delivery in Cancer Treatment

Author : Loutfy H. Madkour
Publisher : CRC Press
ISBN 13 : 100053216X
Total Pages : 558 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Nanoparticle-Based Drug Delivery in Cancer Treatment by : Loutfy H. Madkour

Download or read book Nanoparticle-Based Drug Delivery in Cancer Treatment written by Loutfy H. Madkour and published by CRC Press. This book was released on 2022-03-03 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Focuses on material platforms that establish NPs and both localized and controlled gene silencing Emphasizes the most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment Describes the most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.

Cancer Targeted Drug Delivery

Author : You Han Bae
Publisher : Springer Science & Business Media
ISBN 13 : 1461478766
Total Pages : 720 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Cancer Targeted Drug Delivery by : You Han Bae

Download or read book Cancer Targeted Drug Delivery written by You Han Bae and published by Springer Science & Business Media. This book was released on 2013-08-31 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was conceived from a simple question as to why cancer is so difficult to treat. Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future. This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to tumors. This volume is designed to provide information related to the difficulties in treating cancers through targeted drug delivery, our current understanding of cancer biology, and potential technologies that might be used to achieve enhanced drug delivery to tumors. An ideal drug delivery system for treating cancers would maximize the therapeutic efficacy with minimal side effects in clinical applications. The seemingly improved anticancer efficacy of the current nanoparticle-based formulations needs to be viewed from the context of very poor success rates for translation to human applications. The results of in vitro cell culture models and small animal in vivo experiments have not been extrapolated to clinical applications. Finding the reasons for the lack of successful translation is required if we are to discover approaches to substantially extend the survival time of cancer patients, and hopefully identify cures. Cancer Targeted Drug Delivery: Elusive Dream describes some answers of achieving the so far elusive dream of treating cancers like other chronic diseases with therapies that focus using improved drug delivery systems designed to better align with the unique biological and physiological properties of cancer.