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Principles Of Drug Therapy In Neurology
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Book Synopsis Principles of Drug Therapy in Neurology by : Michael V. Johnston
Download or read book Principles of Drug Therapy in Neurology written by Michael V. Johnston and published by Oxford University Press, USA. This book was released on 1992 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once considered largely untreatable, neurologic disorders have become the newest frontier for breakthrough research in pharmacology. Principles of Drug Therapy in Neurology discusses the latest investigatinal strategies and theories and how they affect current clinical practice. The book details the mechanisms, delivery systems, and efficacy of the latest medication, as the editors outline a "method" for thinking about the action of clinically useful drugs, based on modern information about kinetics, transport to the brain, interaction with neurotransmitter systems and membrane action, etc. All types of major neurologic disorders are discussed.
Book Synopsis The Epilepsies by : Chrysostomos P. Panayiotopoulos
Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.
Book Synopsis Principles of Pharmacology by : David E. Golan
Download or read book Principles of Pharmacology written by David E. Golan and published by Lippincott Williams & Wilkins. This book was released on 2011-12-15 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309450268 Total Pages :97 pages Book Rating :4.3/5 (94 download)
Book Synopsis Developing Multimodal Therapies for Brain Disorders by : National Academies of Sciences, Engineering, and Medicine
Download or read book Developing Multimodal Therapies for Brain Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-13 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.
Book Synopsis Principles and Practice of Restorative Neurology by : Robert R. Young
Download or read book Principles and Practice of Restorative Neurology written by Robert R. Young and published by Butterworth-Heinemann. This book was released on 1992 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Restorative Neurology is a collection of topics in clinical neurology where progress through research has brought concepts of patient management. The collection emphasizes research done clinically and in experimental laboratories and attempts to discuss restorative neurology in the larger context, encompassing biology, neurobiology, and rehabilitative engineering. The book discusses the concept that neurology should be more therapeutic instead of being just diagnostic because of advances in techniques and drugs. An epidemiology of disability and the evaluation of re ...
Book Synopsis Principles of Rehabilitation Medicine by : Raj Mitra
Download or read book Principles of Rehabilitation Medicine written by Raj Mitra and published by McGraw Hill Professional. This book was released on 2018-10-12 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: A high-yield board review and quick reference for Rehabilitation Medicine Rehabilitation Medicine Rapid Review is written primarily for Physical Medicine and Rehabilitation residents preparing for their board exams, and is also an excellent reference for practicing physicians who need a primer on this rapidly growing specialty. With content organized around the American board of Physical Medicine and Rehabilitation core curriculum, this powerful review is enhanced by more than 500 review questions and answers, and concise, bulleted, high-yield text. Readers will find quick answers to common and infrequent issues encountered in rehabilitation medicine
Book Synopsis Principles of Pharmacology for Athletic Trainers by : Joel E. Houglum
Download or read book Principles of Pharmacology for Athletic Trainers written by Joel E. Houglum and published by SLACK Incorporated. This book was released on 2011 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Pharmacology for Athletic Trainers, Second Edition has expanded the comprehensive and unique aspect of pharmacology presented in the best-selling first edition by introducing new information on: * Drug and treatment strategies. * Aspects of Type 1 and Type 2 diabetes, including treatment strategies, the disease process, diagnosis & monitoring of diabetes, and issues that are important for the athletic trainer. * The foundational concepts and pharmacological treatment of schizophrenia, depression, bipolar disorder, various anxiety disorders, and attention deficit-hyperactivity disorder. * Discussion of herbal supplements, federal regulations, and safety & quality issues related to herbal supplements. Dr. Joel Houglum and Dr. Gary Harrelson have updated Principles of Pharmacology for Athletic Trainers, Second Edition to be more user-friendly by incorporating revised information on pharmacokinetic and pharmacodynamic principles, making it even easier for students to understand, while still providing the depth of information desired by faculty. Features of the Second Edition: * Educational prompts are provided in each chapter in the form of an advanced chapter organizer. * Shadow boxes throughout to remind students of previously discussed topics. * Summaries at the end of each section to reinforce learning. * A section in each chapter on the role of the athletic trainer regarding the disease process and drug therapy. * New ancillary materials specifically for faculty that include PowerPoint slides and test bank questions. Principles of Pharmacology for Athletic Trainers, Second Edition will be the go-to resource to determine the best pharmacological treatment strategy and management by athletic trainers.
Book Synopsis Practical Neurology by : José Biller
Download or read book Practical Neurology written by José Biller and published by Lippincott Williams & Wilkins. This book was released on 2012-10-22 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical, concise alternative to existing neurology textbooks. The outline format and standard chapter template offers the reader immediate, comprehensive information. The author is a well-respected educator who has a talent for making neurologic information accessible and understandable. Significant changes have been made to the therapeutics/management portion of the book as well as specific diagnosis-related chapters have been updated. More tables and figures allow the reader to find the information quickly. This book sits between a handbook and a textbook and distinguishes itself in its presentation of material in a problem-oriented format: 35 chapters discuss how to approach the patient with a variety of disorders; the second half of the book discusses treatment options.
Book Synopsis Pharmacotherapy Bedside Guide by : Christopher P. Martin
Download or read book Pharmacotherapy Bedside Guide written by Christopher P. Martin and published by McGraw Hill Professional. This book was released on 2013-07-22 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Select the most appropriate drug in any clinical situation--quickly and easily Developed for use at the point of care, Pharmacotherapy Bedside Guide helps you decide which pharmacotherapy to employ in specific clinical situations. Comprised exclusively of quick-hit tables and algorithms, this carryanywhere companion tells you what treatment the evidence suggests for each illness or disorder. It also details essential drug information, such as benefits, risks, adverse reactions, dosage, interactions with other drugs, and responses. Conveniently organized by specialty and disorder rather than drug, Pharmacotherapy Bedside Guide will prove invaluable when treating patients.
Book Synopsis CURRENT Diagnosis & Treatment Neurology, Second Edition by : John Brust
Download or read book CURRENT Diagnosis & Treatment Neurology, Second Edition written by John Brust and published by McGraw Hill Professional. This book was released on 2011-10-19 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A handy, practical, and management-oriented neurology sourcebook – delivering everything you need in one easy-to-carry volume CURRENT Diagnosis & Treatment Neurology, 2e provides busy clinicians with practical, up-to-date strategies for assessing and managing the most frequently seen neurologic conditions in adults and children. Features Consistent presentation includes Essentials of Diagnosis, Symptoms and Signs, Diagnostic Studies, Differential Diagonsis, Treatment, and Prognosis Coverage of disorders in both adults and children Practical information on common conditions such as headaches, movement disorders, and central nervous system infections Expert help with ischemicand hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, psychiatric problems, and more Thorough coverage of diagnostic tests More than 100 informative photos and illustrations Updated with the latest findings and developments This second edition will be valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic.
Book Synopsis Practical Epilepsy by : Aatif M. Husain, MD
Download or read book Practical Epilepsy written by Aatif M. Husain, MD and published by Springer Publishing Company. This book was released on 2015-09-11 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for busy practitioners and trainees, Practical Epilepsy is the only concise yet exhaustive reference encompassing the broad scope of clinical epilepsy. It contains core information for professionals who wish gain a breadth and depth of knowledge about epilepsy in a shorter amount of time than is required to read large reference books, and is a valuable review tool for self-assessment or exam preparation. Designed to be read cover-to-cover, this highly practical reference covers basic science, assessment, and treatment and uses clear, succinct narratives, lists, tables, and illustrations to present the essential information needed to understand all aspects of epilepsy. The first section of the book introduces the clinical aspects of the science of epileptology with chapters on pathophysiology, genetics, classification, syndromes, epidemiology, etiology, and differential diagnosis. The second section is devoted to diagnostic evaluation, including instrumentation, normal and abnormal EEG, ICU EEG monitoring, scalp and intracranial video EEG monitoring, brain mapping, seizure semiology, neuroimaging, and other techniques. Section three covers treatment with a thorough review of basic principles, all classes of antiepileptic drugs, stimulation therapy, surgery, and dietary and alternative therapies. The final section focuses on special situations and associated concerns, ranging from status epilepticus and psychogenic nonepileptic seizures to migraines and reproductive issues. Key Features: Delivers a concise yet thorough review of the clinical science and current practice of epilepsy medicine Chapter contributions come from a wide array of specialists Presents information in crisp, formatted chapters that distill must-know information for maximum utility Useful for practitioners at any level, from trainees to more experienced clinicians Illustrated with over 100 figures, including EEG readouts and other clinical images Serves as a valuable review tool for self-study or exam preparation About the Editor: Aatif M. Husain, MD, Professor, Department of Neurology, Duke University Medical Center, Durham, NC
Book Synopsis Harrison's Manual of Medicine: 16th Edition by : Dennis L. Kasper
Download or read book Harrison's Manual of Medicine: 16th Edition written by Dennis L. Kasper and published by McGraw Hill Professional. This book was released on 2005-03-09 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authority of Harrison’s at the point of care! Covering the full scope of internal medicine, the new edition of this “mini-textbook” is thoroughly revised to reflect new content areas and quicker retrieval of clinical information. The manual continues to focus on diagnosis and therapy with an emphasis on patient care. Features a new section on Care of the Hospitalized Patient, with a new chapter on Procedures in Internal Medicine as well as a section on patient admittance orders.
Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Book Synopsis Disease Control Priorities, Third Edition (Volume 4) by : Vikram Patel
Download or read book Disease Control Priorities, Third Edition (Volume 4) written by Vikram Patel and published by World Bank Publications. This book was released on 2016-03-10 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.
Book Synopsis Levodopa pharmacokinetics -from stomach to brain by : Maria Nord
Download or read book Levodopa pharmacokinetics -from stomach to brain written by Maria Nord and published by Linköping University Electronic Press. This book was released on 2019-01-07 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and it is caused by a loss of dopamine (DA) producing neurons in the basal ganglia in the brain. The PD patient suffers from motor symptoms such as tremor, bradykinesia and rigidity and treatment with levodopa (LD), the precursor of DA, has positive effects on these symptoms. Several factors affect the availability of orally given LD. Gastric emptying (GE) is one factor and it has been shown to be delayed in PD patients resulting in impaired levodopa uptake. Different enzymes metabolize LD on its way from the gut to the brain resulting in less LD available in the brain and more side effects from the metabolites. By adding dopa decarboxylase inhibitors (carbidopa or benserazide) or COMT-inhibitors (e.g. entacapone) the bioavailability of LD increases significantly and more LD can pass the blood-brain-barrier and be converted to DA in the brain. It has been considered of importance to avoid high levodopa peaks in the brain because this seems to induce changes in postsynaptic dopaminergic neurons causing disabling motor complications in PD patients. More continuously given LD, e.g. duodenal or intravenous (IV) infusions, has been shown to improve these motor complications. Deep brain stimulation of the subthalamic nucleus (STN DBS) has also been proven to improve motor complications and to make it possible to reduce the LD dosage in PD patients. In this doctoral thesis the main purpose is to study the pharmacokinetics of LD in patients with PD and motor complications; in blood and subcutaneous tissue and study the effect of GE and PD stage on LD uptake and the effect of continuously given LD (CDS) on LD uptake and GE; in blood and cerebrospinal fluid (CSF) when adding the peripheral enzyme inhibitors entacapone and carbidopa to LD infusion IV; in brain during STN DBSand during oral or IV LD treatment. To conclude, LD uptake is more favorable in PD patients with less severe disease and GE is delayed in PD patients. No obvious relation between LD uptake and GE or between GE and PD stage is seen and CDS decreases the LD levels. Entacapone increases the maximal concentration of LD in blood and CSF. This is more evident with additional carbidopa and important to consider in avoiding high LD peaks in brain during PD treatment. LD in brain increases during both oral and IV LD treatment and the DA levels follows LD well indicating that PD patients still have capacity to metabolize LD to DA despite probable pronounced nigral degeneration. STN DBS seems to increase putaminal DA levels and together with IV LD treatment also increases LD in brain possibly explaining why it is possible to decrease LD medication after STN DBS surgery. Parkinsons sjukdom (PS) är en av de vanligaste s.k. neurodegenerativasjukdomarna och orsakas av förlust av dopamin(DA)producerande nervceller i hjärnan. Detta orsakar motoriska symptom såsom skakningar, stelhet och förlångsammade rörelser. Levodopa (LD) är ett ämne, som kan omvandlas till DA i hjärnan och ge symptomlindring och det är oftast förstahandsval vid behandling av patienter med PS. Flera faktorer påverkar tillgängligheten av LD, bl.a. den hastighet som magsäcken tömmer sig med och denna verkar förlångsammad hos personer med PS vilket ger sämre tillgänglighet av LD i blodet och därmed i hjärnan. LD bryts även ner i hög grad av olika enzym ute i kroppen vilket leder till mindre mängd LD som hamnar i hjärnan och till fler nedbrytningsprodukter som orsakar biverkningar. Tillägg av enzymhämmare leder till ökad mängd LD som kan nå hjärnan och omvandlas till DA. Det anses viktigt att undvika höga toppar av LD i hjärnan då dessa verkar bidra till utvecklandet av besvärliga motoriska komplikationer hos patienter med PS. Om LD ges mer kontinuerligt, exempelvis som en kontinuerlig infusion in i tarmen eller i blodet, så minskar dessa motoriska komplikationer. Inopererande av stimulatorer i vissa delar av hjärnan (DBS) har också visat sig minska dessa motoriska komplikationer och även resultera i att man kan minska LD-dosen. Huvudsyftet med den här avhandlingen är att studera LD hos patienter med PS; i blod och fettvävnad då LD ges i tablettform och se om det finns något samband med LD-upptag och hastigheten på magsäckstömningen (MT) och om kontinuerligt given LD påverkar LD-upptaget eller MT; i blod och i ryggmärgsvätska då enzymhämmarna entakapon och karbidopa tillsätts LD; i hjärna vid behandling med DBS och då LD ges både som tablett och som infusion i blodet. Sammanfattningsvis kan vi se att LD-upptaget är mer gynnsamt hos patienter med PS i tidigare skede av sjukdomens komplikationsfas. MT är förlångsammad hos patienter med PS och det är inget tydligt samband mellan LD-upptag och MT eller mellan MT och sjukdomsgrad. Kontinuerligt given LD minskar LDnivåerna. Enzymhämmaren entakapon ökar den maximala koncentrationen av LD i blod och ryggmärgsvätska och effekten är mer tydlig vid tillägg av karbidopa vilket är viktigt att ta i beaktande vid behandling av PS för att undvika höga toppar av LD i hjärnan. LD ökar i hjärnan då man behandlar med LD i tablettform och som infusion i blodet och DA-nivåerna i hjärnan följer LD väl vilket visar på att patienter med PS fortfarande kan omvandla LD till DA trots trolig uttalad brist av de DA-producerande nervcellerna i hjärnan. DBS verkar öka DA i vissa områden i hjärnan och tillsammans med LD-infusion i blodet verkar det även öka LD i hjärnan och det kan förklara varför man kan sänka LDdosen efter DBS-operation.
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis Fitzpatrick's Dermatology, 9e by : Sewon Kang
Download or read book Fitzpatrick's Dermatology, 9e written by Sewon Kang and published by . This book was released on 2019 with total page 2272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
