Principles Of Biochemical Toxicology Second Edition

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Principles of Biochemical Toxicology, Third Edition

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 0748407367
Total Pages : 405 pages
Book Rating : 4.7/5 (484 download)

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Book Synopsis Principles of Biochemical Toxicology, Third Edition by : John Timbrell

Download or read book Principles of Biochemical Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Principles of Biochemical Toxicology, Second Edition

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 9780850668322
Total Pages : 415 pages
Book Rating : 4.6/5 (683 download)

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Book Synopsis Principles of Biochemical Toxicology, Second Edition by : John Timbrell

Download or read book Principles of Biochemical Toxicology, Second Edition written by John Timbrell and published by CRC Press. This book was released on 1991-10-28 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following the acclaimed first two editions of Principles of Biochemical Toxicology, the author has expanded the text to include summary sections, questions and model answers and thoroughly revised artwork. These features, plus the new easy-to-read format, will make biochemical toxicology more accessible to undergraduates and postgraduates encountering the subject for the first time. This comprehensive textbook provides a thorough explanation of dose-response relationships, disposition and metabolism, toxic responses to foreign compounds and detailed examples to illustrate mechanisms of toxicity. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Principles of Biochemical Toxicology

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 9781135737849
Total Pages : 405 pages
Book Rating : 4.7/5 (378 download)

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Book Synopsis Principles of Biochemical Toxicology by : John Timbrell

Download or read book Principles of Biochemical Toxicology written by John Timbrell and published by CRC Press. This book was released on 1999-11-01 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology

Author : John A. Timbrell
Publisher :
ISBN 13 : 9781003004301
Total Pages : 405 pages
Book Rating : 4.0/5 (43 download)

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Book Synopsis Principles of Biochemical Toxicology by : John A. Timbrell

Download or read book Principles of Biochemical Toxicology written by John A. Timbrell and published by . This book was released on 1999 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading textbook in biochemical toxicology. Addresses dose-response relationships; metabolism; toxic responses, and provides detailed examples to illustrate mechanisms of toxicity.

Principles of Biochemical Toxicology, Fourth Edition

Author : John A. Timbrell
Publisher : CRC Press
ISBN 13 : 9780849373022
Total Pages : 0 pages
Book Rating : 4.3/5 (73 download)

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Book Synopsis Principles of Biochemical Toxicology, Fourth Edition by : John A. Timbrell

Download or read book Principles of Biochemical Toxicology, Fourth Edition written by John A. Timbrell and published by CRC Press. This book was released on 2008-11-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research into the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. Principles of Biochemical Toxicology, Fourth Edition thoroughly explains dose-response relationships, disposition and metabolism, and toxic responses to foreign compounds, and presents detailed examples to make the mechanisms of toxicity more accessible to students encountering the subject for the first time. Comprehensive in scope with a clear and concise approach, the text includes summary sections, questions and model answers, and thoroughly revised artwork that serves as an essential aid to learning and teaching. New to the Fourth Edition: reorganized sections that cover basic principles followed by sections on different types of toxicity extensive use of examples throughout and numerous explanatory diagrams new material on risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen and asbestos proliferators, domoic acid, bone marrow (benzene), heart (adriamycin), blood (primaquine), biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, ethanol, botox, arsenic, and more questions with answers for each chapter for review and self-checking expanded and updated chapter bibliographies

Principles of Toxicology, Second Edition

Author : Stine Karen
Publisher : CRC Press
ISBN 13 : 084932856X
Total Pages : 392 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Principles of Toxicology, Second Edition by : Stine Karen

Download or read book Principles of Toxicology, Second Edition written by Stine Karen and published by CRC Press. This book was released on 2006-01-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Introduction to Toxicology, Third Edition

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 9780415247634
Total Pages : 238 pages
Book Rating : 4.2/5 (476 download)

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Book Synopsis Introduction to Toxicology, Third Edition by : John Timbrell

Download or read book Introduction to Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 2001-11-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Clinical Toxicology

Author : Frank A. Barile
Publisher : CRC Press
ISBN 13 : 142009226X
Total Pages : 484 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Clinical Toxicology by : Frank A. Barile

Download or read book Clinical Toxicology written by Frank A. Barile and published by CRC Press. This book was released on 2010-02-15 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare

Principles of Toxicology

Author : Stephen M. Roberts
Publisher : John Wiley & Sons
ISBN 13 : 0470907916
Total Pages : 496 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Principles of Toxicology by : Stephen M. Roberts

Download or read book Principles of Toxicology written by Stephen M. Roberts and published by John Wiley & Sons. This book was released on 2015-01-12 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

In Vitro Toxicology, Second Edition

Author : Shayne C. Gad
Publisher : CRC Press
ISBN 13 : 1560327693
Total Pages : 419 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis In Vitro Toxicology, Second Edition by : Shayne C. Gad

Download or read book In Vitro Toxicology, Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2000-11-02 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.

Molecular and Biochemical Toxicology

Author : Robert C. Smart
Publisher : John Wiley & Sons
ISBN 13 : 1119042410
Total Pages : 1060 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Molecular and Biochemical Toxicology by : Robert C. Smart

Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2018-01-04 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Principles of Toxicology

Author : Phillip L. Williams
Publisher : John Wiley & Sons
ISBN 13 : 0471459232
Total Pages : 625 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Principles of Toxicology by : Phillip L. Williams

Download or read book Principles of Toxicology written by Phillip L. Williams and published by John Wiley & Sons. This book was released on 2003-10-10 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms

Principles of Toxicology Testing, Second Edition

Author : Frank A Barile
Publisher : CRC Press
ISBN 13 : 1842145282
Total Pages : 368 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Principles of Toxicology Testing, Second Edition by : Frank A Barile

Download or read book Principles of Toxicology Testing, Second Edition written by Frank A Barile and published by CRC Press. This book was released on 2013-04-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.

Principles and Practice of Toxicology in Public Health

Author : Ira S. Richards
Publisher : Jones & Bartlett Learning
ISBN 13 : 1284065995
Total Pages : 559 pages
Book Rating : 4.2/5 (84 download)

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Book Synopsis Principles and Practice of Toxicology in Public Health by : Ira S. Richards

Download or read book Principles and Practice of Toxicology in Public Health written by Ira S. Richards and published by Jones & Bartlett Learning. This book was released on 2013-07-26 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: All public health professionals should have some level of knowledge of the basic principles of Toxicology. Whether dealing with issues as diverse as a workers’ compensation claim for a job-related exposure and injury or the removal of toxic wastes from an urban community, public health professionals must be able to communicate with each other, the public, and our political leaders concerning how chemicals can, and the conditions under which they may, realistically produce harm. Principles and Practice of Toxicology in Public Health provides students with an understanding of the nature and scope of the discipline, so that they may be prepared to participate in a meaningful way in the often highly visible problem-solving and decision-making processes required of public health professionals. In four sections, it offers an introduction to the field, as well as the basics of toxicology principles, systemic toxicity, and toxicology practice. The text is immediately readable for the student with little technical background. The Second Edition is a thorough update that has been expaneded with a new chapter on endocrine toxicology. Instructor Resources: Instructor Manual, PowerPoint, TestBank

Mechanistic Toxicology

Author : Urs A. Boelsterli
Publisher : CRC Press
ISBN 13 : 9780849372728
Total Pages : 424 pages
Book Rating : 4.3/5 (727 download)

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Book Synopsis Mechanistic Toxicology by : Urs A. Boelsterli

Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Study Toxicology Through Questions

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 0203484010
Total Pages : 144 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Study Toxicology Through Questions by : John Timbrell

Download or read book Study Toxicology Through Questions written by John Timbrell and published by CRC Press. This book was released on 2017-08-25 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of questions with answers for students of toxicology. The questions are a mixture of short answer, problem-solving, data interpretation and multiple choice and cover all the major areas of toxicology.

Introduction to Toxicology

Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 1000026981
Total Pages : 238 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Introduction to Toxicology by : John Timbrell

Download or read book Introduction to Toxicology written by John Timbrell and published by CRC Press. This book was released on 2019-10-30 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.