Preclinical Mri Of The Kidney

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Preclinical MRI of the Kidney

Author : Andreas Pohlmann
Publisher : Humana
ISBN 13 : 9781071609804
Total Pages : 0 pages
Book Rating : 4.6/5 (98 download)

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Book Synopsis Preclinical MRI of the Kidney by : Andreas Pohlmann

Download or read book Preclinical MRI of the Kidney written by Andreas Pohlmann and published by Humana. This book was released on 2022-02-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preface... Table of Contents... Contributing Authors... Part I Introduction 1. Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies Andreas Pohlmann, Susan J. Back, Andrea Fekete, Iris Friedli, Stefanie Hectors, Neil Peter Jerome, Min-Chi Ku, Dario Livio Longo, Martin Meier, Jason M. Millward, João S. Periquito, Erdmann Seeliger, Suraj D. Serai, Sonia Waiczies, Steven Sourbron, Christoffer Laustsen, and Thoralf Niendorf Part II Animal Models, Preparation, Monitoring, and Physiological Interventions 2. Animal Models of Renal Pathophysiology and Disease Adam Hosszu, Tamas Kaucsar, Erdmann Seeliger, and Andrea Fekete 3. Preparation and Monitoring of Small Animals in Renal MRI Tamas Kaucsar, Adam Hosszu, Erdmann Seeliger, Henning M. Reimann, and Andrea Fekete 4. Reversible (Patho-)Physiologically Relevant Test Interventions: Rationale and Examples Kathleen Cantow, Mechthild Ladwig-Wiegard, Bert Flemming, Andrea Fekete, Adam Hosszu, Erdmann Seeliger 5. Preparation of Ex Vivo Rodent Phantoms for Developing, Testing, and Training MR Imaging of the Kidney and Other Organs Jason M. Millward, João S. Periquito, Paula Ramos Delgado, Christian Prinz, Thoralf Niendorf, and Sonia Waiczies Part III Basic Concepts of Measurement Techniques 6. Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts Kathleen Cantow, Roger G. Evans, Dirk Grosenick, Thomas Gladytz, Thoralf Niendorf, Bert Flemming, and Erdmann Seeliger 7. Ultrasound and Photoacoustic Imaging of the Kidney: Basic Concepts and Protocols Sandra Meyer, Dieter Fuchs, and Martin Meier 8. Hardware Considerations for Preclinical Magnetic Resonance of the Kidney Paula Ramos Delgado, Ekkehard Küstermann, André Kühne, Jason M. Millward, Thoralf Niendorf, Andreas Pohlmann, and Martin Meier 9. MRI Mapping of Renal T1: Basic Concept Stefanie Hectors, Sabrina Doblas, Philippe Garteiser, Gwenaël Pagé, Bernard E. Van Beers, John C. Waterton, and Octavia Bane 10. MRI Mapping of the Blood Oxygenation Sensitive Parameter T2* in the Kidney: Basic Concept Lu-Ping Li, Bradley Hack, Erdmann Seeliger, and Pottumarthi V. Prasad 11. Renal Diffusion Weighted Imaging (DWI) for Apparent Diffusion Coefficient (ADC), Intra Voxel Incoherent Motion (IVIM), and Diffusion Tensor Imaging (DTI): Basic Concept Neil Peter Jerome, Anna Caroli, and Alexandra Ljimani 12. Dynamic Contrast Enhancement (DCE)-MRI Derived Renal Perfusion and Filtration: Basic Concepts Michael Pedersen, Pietro Irrera, Walter Dastrù, Frank G. Zöllner, Kevin M. Bennett, Scott C. Beeman, G. Larry Bretthorst, Joel R. Garbow, and Dario Livio Longo 13. Non-Invasive Renal Perfusion Measurement Using Arterial Spin Labelling (ASL) MRI: Basic Concept Min-Chi Ku, María A. Fernández-Seara, Frank Kober, and Thoralf Niendorf 14. Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI: Basic Concepts Dario Livio Longo, Pietro Irrera, Lorena Consolino, Phillip Zhe Sun, and Michael T. McMahon 15. Sodium (23Na) MRI of the Kidney: Basic Concept James T. Grist, Esben Søvsø Hansen, Frank G. Zöllner, and Christoffer Laustsen 16. Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concepts Cornelius von Morze, Galen D. Reed, Zhen J. Wang, Michael A. Ohliger, and Christoffer Laustsen 17. Functional Imaging Using Fluorine (19F) MR Methods: Basic Concepts Sonia Waiczies, Christian Prinz, Ludger Starke, Jason M. Millward, Paula Ramos Delgado, Jens Rosenberg, Marc Nazaré, Helmar Waiczies, Andreas Pohlmann, and Thoralf Niendorf 18. MR Elastography of the Abdomen: Basic Concepts Suraj D. Serai and Meng Yin Part IV Experimental Protocols 19. Monitoring Renal H

Preclinical MRI of the Kidney

Author : Andreas Pohlmann
Publisher : Humana
ISBN 13 : 9781071609774
Total Pages : 725 pages
Book Rating : 4.6/5 (97 download)

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Book Synopsis Preclinical MRI of the Kidney by : Andreas Pohlmann

Download or read book Preclinical MRI of the Kidney written by Andreas Pohlmann and published by Humana. This book was released on 2021-01-22 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and improve the reproducibility of renal imaging research. Chapters provide guidance for exploring, using and developing small animal renal MRI in your laboratory as a unique tool for advanced in vivo phenotyping, diagnostic imaging, and research into potential new therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Preclinical MRI of the Kidney: Methods and Protocols is a valuable resource and will be of importance to anyone interested in the preclinical aspect of renal and cardiorenal diseases in the fields of physiology, nephrology, radiology, and cardiology. This publication is based upon work from COST Action PARENCHIMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers.

Preclinical MRI of the Kidney

Author : Andreas Pohlmann
Publisher :
ISBN 13 : 9781071609781
Total Pages : 725 pages
Book Rating : 4.6/5 (97 download)

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Book Synopsis Preclinical MRI of the Kidney by : Andreas Pohlmann

Download or read book Preclinical MRI of the Kidney written by Andreas Pohlmann and published by . This book was released on 2021 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and improve the reproducibility of renal imaging research. Chapters provide guidance for exploring, using and developing small animal renal MRI in your laboratory as a unique tool for advanced in vivo phenotyping, diagnostic imaging, and research into potential new therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Preclinical MRI of the Kidney: Methods and Protocols is a valuable resource and will be of importance to anyone interested in the preclinical aspect of renal and cardiorenal diseases in the fields of physiology, nephrology, radiology, and cardiology. This publication is based upon work from COST Action PARENCHIMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers.

Kidney Mri: Preclinical Applications

Author : Sarah Brown
Publisher : States Academic Press
ISBN 13 : 9781639893171
Total Pages : 252 pages
Book Rating : 4.8/5 (931 download)

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Book Synopsis Kidney Mri: Preclinical Applications by : Sarah Brown

Download or read book Kidney Mri: Preclinical Applications written by Sarah Brown and published by States Academic Press. This book was released on 2021-11-16 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance is a medical imaging technique which is used for taking detailed pictures of the soft tissues and organs of the body through radio waves and magnets. Unlike X-rays and CT scans, it does not make use of ionizing radiation. Therefore it can be used in cases where exposure to radiation is dangerous. The soft tissues as well as masses, cystic structures, lymph nodes and blood vessels can be seen in detail. The MRI functions by directing radio waves at the molecules of water inside the body, exciting and relaxing the protons in them. This energy from the water molecules is read and a 3-D image is produced which shows the different types of tissue. It can be used for the detection of acute renal failure and chronic kidney disease. It also helps in finding out changes in kidney function which could indicate inflammation or obstruction. The book aims to shed light on some of the unexplored aspects of magnetic resonance imaging and its clinical and experimental applications. It is an upcoming technique in the field of medical science that has undergone rapid development over the past few decades. Researchers and students in this field will be assisted by this book.

Magnetic Resonance Elastography

Author : Sudhakar K. Venkatesh
Publisher : Springer
ISBN 13 : 1493915754
Total Pages : 137 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Magnetic Resonance Elastography by : Sudhakar K. Venkatesh

Download or read book Magnetic Resonance Elastography written by Sudhakar K. Venkatesh and published by Springer. This book was released on 2014-10-01 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to cover the groundbreaking development and clinical applications of Magnetic Resonance Elastography, this book is essential for all practitioners interested in this revolutionary diagnostic modality. The book is divided into three sections. The first covers the history of MRE. The second covers technique and clinical applications of MRE in the liver with respect to fibrosis, liver masses, and other diseases. Case descriptions are presented to give the reader a hands-on approach. The final section presents the techniques, sequence and preliminary results of applications in other areas of the body including muscle, brain, lung, heart, and breast.

MRI from Picture to Proton

Author : Donald W. McRobbie
Publisher : Cambridge University Press
ISBN 13 : 1316688259
Total Pages : 405 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis MRI from Picture to Proton by : Donald W. McRobbie

Download or read book MRI from Picture to Proton written by Donald W. McRobbie and published by Cambridge University Press. This book was released on 2017-04-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Chemical Exchange Saturation Transfer Imaging

Author : Michael T. McMahon
Publisher : CRC Press
ISBN 13 : 1315340755
Total Pages : 496 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Chemical Exchange Saturation Transfer Imaging by : Michael T. McMahon

Download or read book Chemical Exchange Saturation Transfer Imaging written by Michael T. McMahon and published by CRC Press. This book was released on 2017-01-12 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo applications. CEST is a powerful MRI contrast mechanism with unique features, and the rapid expansion it has seen over the past 15 years since its original discovery in 2000 has created a need for a graduate-level handbook describing all aspects of pre-clinical, translational, and clinical CEST imaging. The book provides an illustrated historical perspective by leaders at the five key sites who developed CEST imaging, from the initial saturation transfer NMR experiments performed in the 1960s in Stockholm, Sweden, described by Sture Forsén, to the work on integrating the basic principles of CEST into imaging by Robert Balaban, Dean Sherry, Silvio Aime, and Peter van Zijl in the United States and Italy. The editors, Drs. Michael T. McMahon, Assaf A. Gilad, Jeff W. M. Bulte, and Peter C. M. van Zijl, have been pioneers developing this field at the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute including contributions to Nature Medicine, Nature Biotechnology, Nature Materials, and the Proceedings of the National Academy of Sciences. As recognition for their initial development of the field, Drs. van Zijl and Balaban were awarded the Laukien Prize in April 2016, established in 1999 to honor the memory of Professor Gunther Laukien, a co-founder of Bruker Biospin GmbH.

Oxford Textbook of Urological Surgery

Author : Freddie C. Hamdy
Publisher : Oxford University Press
ISBN 13 : 0191022527
Total Pages : 1264 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Urological Surgery by : Freddie C. Hamdy

Download or read book Oxford Textbook of Urological Surgery written by Freddie C. Hamdy and published by Oxford University Press. This book was released on 2017-10-06 with total page 1264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a comprehensive guide, the Oxford Textbook of Urological Surgery is a practical resource mapped to the curriculum for urological training as approved by the General Medical Council (GMC), making it particularly useful in preparation for the Intercollegiate Examination. Presented in a clear and accessible way, this evidence based volume covers all major areas, including functional urology, stone disease, infection, andrology, nephrology, transplantation, uroradiology, and paediatric urology. This highly illustrated full colour textbook has an innovative and user-friendly style, including over 500 photographs, clinical images, and line drawings. Bringing together the expertise of over 100 specialist contributors in the field, the Oxford Textbook of Urological Surgery is a highly valuable source of information, and will become the standard reference text for all who study urological disease and its treatment.

Fluorine Magnetic Resonance Imaging

Author : Ulrich Flogel
Publisher : CRC Press
ISBN 13 : 1315340933
Total Pages : 462 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Fluorine Magnetic Resonance Imaging by : Ulrich Flogel

Download or read book Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and published by CRC Press. This book was released on 2016-10-26 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Metronomic Chemotherapy

Author : Guido Bocci
Publisher : Springer
ISBN 13 : 3662436043
Total Pages : 295 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Metronomic Chemotherapy by : Guido Bocci

Download or read book Metronomic Chemotherapy written by Guido Bocci and published by Springer. This book was released on 2014-09-04 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Cancer and the Kidney

Author : Eric P. Cohen
Publisher : Oxford University Press, USA
ISBN 13 : 0199580197
Total Pages : 382 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Cancer and the Kidney by : Eric P. Cohen

Download or read book Cancer and the Kidney written by Eric P. Cohen and published by Oxford University Press, USA. This book was released on 2010-11-11 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.

Magnetic Particle Imaging

Author : Tobias Knopp
Publisher : Springer Science & Business Media
ISBN 13 : 364204199X
Total Pages : 211 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Magnetic Particle Imaging by : Tobias Knopp

Download or read book Magnetic Particle Imaging written by Tobias Knopp and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.

Advanced Clinical MRI of the Kidney

Author : Suraj D. Serai
Publisher : Springer Nature
ISBN 13 : 3031401697
Total Pages : 463 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Advanced Clinical MRI of the Kidney by : Suraj D. Serai

Download or read book Advanced Clinical MRI of the Kidney written by Suraj D. Serai and published by Springer Nature. This book was released on 2023-12-19 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers the concepts of quantitative MRI for kidney imaging. Kidney MRI holds incredible promise for making a quantum leap in improving diagnosis and care of patients with a multitude of diseases, by moving beyond the limitations and restrictions of current routine clinical practice. Clinical kidney MRI is advancing with ever increasing rapidity, and yet, it is still not good enough. Several roadblocks still slow the pace of progress, particularly inefficient education of renal MR researchers, and lack of harmonization of approaches that limits the sharing of results among multiple research groups. With the help of this book, we aim to address these limitations, by providing a comprehensive collection of more chapters on MRI methods that serve as a foundational resource for clinical kidney MRI studies. This includes chapters describing the fundamental principles underlying a variety of kidney MRI methods, step-by-step protocols for executing kidney MRI studies, and detailed guides for post-processing and data analysis. This collection serves as a crucial part of a roadmap towards conducting kidney MRI studies in a robust and reproducible way, that promotes the standardization and sharing of data, and ultimately, clinical translation. Chapters are divided into three parts: MRI physics and acquisition protocols, post-processing and data analysis methods, and clinical applications. The first section includes MRI physics background and describe a detailed step by step MRI acquisition protocol. If a clinician would like to perform a renal MRI – this would include the parameters to set up the acquisition on the scanner. By this section, the reader should have the details to be able to successfully collect human renal MR images. In the second section, expert authors describe methods on how to post-process and analyze the data. By this section, the reader should have the details to be able to successfully generate quantitative data from the human renal MR images. In the final section, chapters show clinical examples of various methods. Authors share examples of multi-parametric renal MRI that are being used in clinical practice. This is an ideal guide for clinicians from radiology, nephrology, physiology, clinical scientists, and as well as basic scientists and experts in imaging sciences and physics of kidney MRI. It also provides an opportunity to students, trainees, and post-doctoral fellows to learn about these kidney MRI techniques.

Oxford Handbook of Nephrology and Hypertension

Author : Simon Steddon
Publisher : Oxford University Press
ISBN 13 : 0199651612
Total Pages : 1002 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Handbook of Nephrology and Hypertension by : Simon Steddon

Download or read book Oxford Handbook of Nephrology and Hypertension written by Simon Steddon and published by Oxford University Press. This book was released on 2014-03 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the Oxford Textbook of Clinical Nephrology and companion to the Oxford Handbook of Dialysis, this handbook provides clear information and practical advice about the day-to-day management of patients with renal disease.

Genitourinary Pathology E-Book

Author : Ming Zhou
Publisher : Elsevier Health Sciences
ISBN 13 : 0323188338
Total Pages : 723 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Genitourinary Pathology E-Book by : Ming Zhou

Download or read book Genitourinary Pathology E-Book written by Ming Zhou and published by Elsevier Health Sciences. This book was released on 2014-10-20 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genitourinary Pathology, by Drs. Ming Zhou and Cristina Magi-Galluzzi, a volume in the Foundations in Diagnostic Pathology Series, packs all of today's most essential information on genitourinary pathology into a compact, high-yield format! Well-organized and segmented by type of infectious organism, the book's pragmatic approach complemented by abundant full-color, high-quality photomicrographs and clinical photos, and at-a-glance tables makes it easy to access the information you need to quickly and accurately detect and identify molecular and genetic mechanisms of disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Easily review normal histology before examining abnormal findings so you can avoid false positives. Gain a superb visual understanding of important histologic features with hundreds of full-color illustrations representing a wide variety of pathologic lesions. Benefit from the same highly practical format as other titles in this series: consistent headings throughout, summary boxes for pathologic and clinical features, high quality photomicrographs and clinical photos, and a logical organization by type of infectious organism. Avoid incorrect diagnoses with a separate section on artifacts and pitfalls that highlights common problems you may encounter. Get up-to-date, comprehensive coverage of the field, including new renal cell carcinoma subtypes and intraductal carcinoma of the prostate; newer immunohistochemical and molecular markers; and updates to the Gleason Grading system for prostate cancer, Fuhrman Grading system for renal cell carcinoma, and TNM classification for GU malignancies.

Animal Models in Cancer Drug Discovery

Author : Asfar Azmi
Publisher : Academic Press
ISBN 13 : 0128147059
Total Pages : 470 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Animal Models in Cancer Drug Discovery by : Asfar Azmi

Download or read book Animal Models in Cancer Drug Discovery written by Asfar Azmi and published by Academic Press. This book was released on 2019-04-16 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field. Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid systems, humanized and other models in modern biology paradigms that are enhancing research in the field of drug discover Covers the use of these models in personalized medicine, immunotherapy, toxicology, pre-IND assessments and related drug development arenas Presents protocols, procedures, and a comprehensive glossary to help new readers understand technical terms and specialized nomenclature

Translocator Protein (TSPO)

Author : Giovanni Natile
Publisher : MDPI
ISBN 13 : 3038427578
Total Pages : 177 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Translocator Protein (TSPO) by : Giovanni Natile

Download or read book Translocator Protein (TSPO) written by Giovanni Natile and published by MDPI. This book was released on 2018-03-05 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS