Precision Medicine And Distributive Justice

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Precision Medicine and Distributive Justice

Author : Leonard M. Fleck
Publisher : Oxford University Press
ISBN 13 : 0197647723
Total Pages : 433 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis Precision Medicine and Distributive Justice by : Leonard M. Fleck

Download or read book Precision Medicine and Distributive Justice written by Leonard M. Fleck and published by Oxford University Press. This book was released on 2022 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastatic cancer and costly precision medicines generate extremely complex problems of health care justice. Targeted cancer therapies yield only very marginal gains in life expectancy for most patients at very great cost, thereby threatening the just allocation of limited health care resources. Philosophers have high hopes for the utility of their theories of justice in addressing the challenges of resource allocation; however, none of these theories can address adequately the "wicked" ethical problems that have resulted from these targeted therapies. What we need instead, bioethicist Leonard M. Fleck argues, is a political conception of health care justice, following Rawls, and a fair and inclusive process of rational democratic deliberation governed by public reason. His account makes the basic assumption that we have only limited health care resources to meet unlimited health care needs generated by emerging medical technologies. The primary ethical and political virtue of rational democratic deliberation is that it allows citizens to fashion autonomously shared understandings of how to fairly address the complex problems of health care justice generated by precision medicine. While ideally just outcomes are a moral and political impossibility, "wicked" problems can metastasize if rationing decisions are made invisibly--in ways effectively hidden from those affected by those decisions. As Fleck demonstrates, a fair and inclusive process of democratic deliberation could make these "wicked" problems visible, and subject, to public reason.

Global Perspectives on Precision Medicine

Author : Evangel Sarwar
Publisher : Springer Nature
ISBN 13 : 303128593X
Total Pages : 239 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Global Perspectives on Precision Medicine by : Evangel Sarwar

Download or read book Global Perspectives on Precision Medicine written by Evangel Sarwar and published by Springer Nature. This book was released on 2023-04-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the promises of Precision Medicine (PM) and the challenges of its implementation in daily clinical routine, while addressing the anticipated ethical and social implications. It is the first book that critically analyzes the potential and the dilemmas relevant to genomics and precision medicine from healthcare, public health and global perspectives. The nine chapters presented in this book elaborate on pharmacogenomics' crucial role in maximizing the potential benefits and minimizing medication's potential risks in groups of people, especially in cancer treatment and other health conditions. Infectious and non-communicable diseases (NCDs) are also discussed in this book by identifying challenges and ways to overcome them. Essential concepts are addressed, such as health-related benefits and harm to individuals and the broader community, including threats to individual privacy and autonomy, which warrant just distribution of scarce resources. The book also identifies and addresses the lack of competency in the healthcare workforce in the era of PM and discusses the path to laying the ethical foundation for the implementation of PM in healthcare organizations.

Distributive Justice and the New Medicine

Author : George Patrick Smith
Publisher : Edward Elgar Pub
ISBN 13 : 9781847207579
Total Pages : 187 pages
Book Rating : 4.2/5 (75 download)

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Book Synopsis Distributive Justice and the New Medicine by : George Patrick Smith

Download or read book Distributive Justice and the New Medicine written by George Patrick Smith and published by Edward Elgar Pub. This book was released on 2008-01-01 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major new work by one of the world's leading medical lawyers. 'While much has been written about the various issues addressed in this book - genetics, cloning, informed consent, organ donation - Smith's book moves beyond traditional legal analysis, tying these issues together by examining them through the lens of distributive justice. He thus provides the reader with a unique and valuable perspective on this important area. Distributive Justice and the New Medicine will be of interest to all those interested in health law and bioethics and in particular for those interested in distributive justice.' - Belinda Bennett, Journal of Law, Social Justice and Global Development

Progress and Challenges in Precision Medicine

Author : Mukesh Verma
Publisher : Academic Press
ISBN 13 : 0128095024
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Progress and Challenges in Precision Medicine by : Mukesh Verma

Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Summarizing Population Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309060990
Total Pages : 91 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Summarizing Population Health by : Institute of Medicine

Download or read book Summarizing Population Health written by Institute of Medicine and published by National Academies Press. This book was released on 1998-05-01 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Personalized Medicine in Healthcare Systems

Author : Nada Bodiroga-Vukobrat
Publisher : Springer
ISBN 13 : 3030164659
Total Pages : 405 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Personalized Medicine in Healthcare Systems by : Nada Bodiroga-Vukobrat

Download or read book Personalized Medicine in Healthcare Systems written by Nada Bodiroga-Vukobrat and published by Springer. This book was released on 2019-08-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers scientific contributions on comprehensive approaches to personalized medicine. In a systematic and clear manner, it provides extensive information on the methodological, technological, and clinical aspects of high-throughput analytics, nanotechnology approaches, microbiota/human interactions, in-vitro fertilization and preimplantation, and various diseases like cancer.Moreover, the book analyzes the social and legal aspects of social security systems, healthcare systems and EU law – e.g. the role of solidarity, regulatory possibilities and obstacles, justice and equality, privacy/disclosure of data, and the right to know – from an interdisciplinary perspective. Lastly, it explores the economical and ethical context in the fields of business models, intellectual property issues, the patient/physician relationship, and price discrimination.

Personalised Medicine, Individual Choice and the Common Good

Author : Britta Chongkol van Beers
Publisher : Cambridge University Press
ISBN 13 : 1108473911
Total Pages : 321 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Personalised Medicine, Individual Choice and the Common Good by : Britta Chongkol van Beers

Download or read book Personalised Medicine, Individual Choice and the Common Good written by Britta Chongkol van Beers and published by Cambridge University Press. This book was released on 2018-11-22 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asks whether personalised medicine is superior to 'one-size-fits-all' treatment. Does it elevate individual choice above the common good?

The Postgenomic Condition

Author : Jenny Reardon
Publisher : University of Chicago Press
ISBN 13 : 022651045X
Total Pages : 320 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis The Postgenomic Condition by : Jenny Reardon

Download or read book The Postgenomic Condition written by Jenny Reardon and published by University of Chicago Press. This book was released on 2017-12-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue

Just Caring

Author : Leonard M. Fleck
Publisher : Oxford University Press
ISBN 13 : 0195128044
Total Pages : 479 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Just Caring by : Leonard M. Fleck

Download or read book Just Caring written by Leonard M. Fleck and published by Oxford University Press. This book was released on 2009 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to be a "just" and "caring" society when we have only limited resources to meet unlimited health care needs? Do we believe that all lives are of equal value? Is human life priceless? Should a "just" and "caring" society refuse to put limits on health care spending? In Just Caring, Leonard Fleck reflects on the central moral and political challenges of health reform today. He cites the millions of Americans who go without health insurance, thousands of whom die prematurely, unable to afford the health care needed to save their lives. Fleck considers these deaths as contrary to our deepest social values, and makes a case for the necessity of health care rationing decisions. The core argument of this book is that no one has a moral right to impose rationing decisions on others if they are unwilling to impose those same rationing decisions on themselves in the same medical circumstances. Fleck argues we can make health care rationing fair, in ways that are mutually respectful, if we engage in honest rational democratic deliberation. Such civic engagement is rare in our society, but the alternative is endless destructive social controversy that is neither just nor caring.

Targeted Therapies in Oncology, Second Edition

Author : Giuseppe Giaccone
Publisher : CRC Press
ISBN 13 : 1842145452
Total Pages : 500 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Targeted Therapies in Oncology, Second Edition by : Giuseppe Giaccone

Download or read book Targeted Therapies in Oncology, Second Edition written by Giuseppe Giaccone and published by CRC Press. This book was released on 2013-10-21 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.

Precision Public Health

Author : Tarun Weeramanthri
Publisher : Frontiers Media SA
ISBN 13 : 2889455017
Total Pages : 149 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Precision Public Health by : Tarun Weeramanthri

Download or read book Precision Public Health written by Tarun Weeramanthri and published by Frontiers Media SA. This book was released on 2018-06-25 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.

Precision Medicine and Artificial Intelligence

Author : Michael Mahler
Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 300 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Precision Medicine and Artificial Intelligence by : Michael Mahler

Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Personalized Medicine

Author : Barbara Prainsack
Publisher : NYU Press
ISBN 13 : 1479856908
Total Pages : 288 pages
Book Rating : 4.4/5 (798 download)

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Book Synopsis Personalized Medicine by : Barbara Prainsack

Download or read book Personalized Medicine written by Barbara Prainsack and published by NYU Press. This book was released on 2017-12-19 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside today's data-driven personalized medicine, and the time, effort, and information required from patients to make it a reality Medicine has been personal long before the concept of “personalized medicine” became popular. Health professionals have always taken into consideration the individual characteristics of their patients when diagnosing, and treating them. Patients have cared for themselves and for each other, contributed to medical research, and advocated for new treatments. Given this history, why has the notion of personalized medicine gained so much traction at the beginning of the new millennium? Personalized Medicine investigates the recent movement for patients’ involvement in how they are treated, diagnosed, and medicated; a movement that accompanies the increasingly popular idea that people should be proactive, well-informed participants in their own healthcare. While it is often the case that participatory practices in medicine are celebrated as instances of patient empowerment or, alternatively, are dismissed as cases of patient exploitation, Barbara Prainsack challenges these views to illustrate how personalized medicine can give rise to a technology-focused individualism, yet also present new opportunities to strengthen solidarity. Facing the future, this book reveals how medicine informed by digital, quantified, and computable information is already changing the personalization movement, providing a contemporary twist on how medical symptoms or ailments are shared and discussed in society. Bringing together empirical work and critical scholarship from medicine, public health, data governance, bioethics, and digital sociology, Personalized Medicine analyzes the challenges of personalization driven by patient work and data. This compelling volume proposes an understanding that uses novel technological practices to foreground the needs and interests of patients, instead of being ruled by them.

Medicine and Social Justice

Author : Rosamond Rhodes
Publisher : Oxford University Press
ISBN 13 : 0199930813
Total Pages : pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Medicine and Social Justice by : Rosamond Rhodes

Download or read book Medicine and Social Justice written by Rosamond Rhodes and published by Oxford University Press. This book was released on 2012-07-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Because medicine can preserve life, restore health and maintain the body's functions, it is widely acknowledged as a basic good that just societies should provide for their members. Yet, there is wide disagreement over the scope and content of what to provide, to whom, how, when, and why. In this unique and comprehensive volume, some of the best-known philosophers, physicians, legal scholars, political scientists, and economists writing on the subject discuss what social justice in medicine should be. Their contributions deepen our understanding of the theoretical and practical issues that run through the contemporary debate. The forty-two chapters in this reorganized second edition of Medicine and Social Justice update and expand upon the thirty-four chapters of the 2002 first edition. Eighteen chapters from the original volume are revised to address policy changes and challenging issues that have emerged in the intervening decade. Twenty-two of the chapters in this edition are entirely new. The treatment of foundational theory and conceptual issues related to access to health care and rationing medical resources have been expanded to provide a more comprehensive and nuanced discussion of the background concepts that underlie distributive justice debates, with global perspectives on health and well-being added. New additions to the section on health care justice for specific populations include chapters on health care for the chronically ill, soldiers, prisoners, the severely cognitively disabled, and the LGBT population. The section devoted to dilemmas and priorities addresses an array of topics that have recently become especially pressing because of new technologies or altered policies. New chapters address questions of justice related to genetics, medical malpractice, research on human subjects, pandemic and disaster planning, newborn screening, and justice for the brain dead and those with profound neurological injury. Reviews of the first edition: "This compilation brings a variety of perspectives, national settings, and disciplinary backgrounds to the topic and provides a unique survey of theoretical and applied thinking about the connections between health care and social justice... Physicians and others interested in this field will find this book an engaging introduction to the theoretical and practical challenges pertaining to social justice and health care." New England Journal of Medicine "Although much work in bioethics has focused on clinical encounters, there has been a current of discussion about questions of social justice for decades-at least since the allocation of access to dialysis was widely understood in the 1960s to be a matter of justice, not of medical judgment. This volume will facilitate heightened awareness and deeper discussion of such issues." JAMA "Impressively, the editors have chosen an array of essays that explore the philosophical and bioethical foundations of distributive justice; review the current practice of rationing and patients' access to care in a number of different countries; highlight the issues raised by various special needs groups; and then wrestle with some dilemmas in assessing priorities in distributing healthcare... This book is an excellent resource. " Doody's

Beyond Bioethics

Author : Osagie K. Obasogie
Publisher : Univ of California Press
ISBN 13 : 0520277821
Total Pages : 546 pages
Book Rating : 4.5/5 (22 download)

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Book Synopsis Beyond Bioethics by : Osagie K. Obasogie

Download or read book Beyond Bioethics written by Osagie K. Obasogie and published by Univ of California Press. This book was released on 2018-03-13 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: "For several decades, the field of bioethics has played a dominant role in shaping the way society thinks about ethical problems related to developments in science, technology, and medicine. But its traditional emphases on, for example, doctor-patient relationships, informed consent, and individual autonomy have led the field to not be fully responsive to the challenges posed by new human biotechnologies such as assisted reproduction, human genetic enhancement, and DNA forensics. Beyond Bioethics provides a focused overview for students and others grappling with the profound social dilemmas posed by these developments. It brings together the work of cutting-edge thinkers from diverse fields of study and public engagement, all of them committed to a new perspective that is grounded in social justice and public interest values. The contributors to this volume seek to define an emerging field of scholarly, policy, and public concern: a new biopolitics."--Provided by publisher.

Applying Big Data to Address the Social Determinants of Health in Oncology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309679060
Total Pages : 83 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Applying Big Data to Address the Social Determinants of Health in Oncology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Applying Big Data to Address the Social Determinants of Health in Oncology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-14 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Academies of Sciences, Engineering, and Medicine held the workshop Applying Big Data to Address the Social Determinants of Health in Oncology on October 28â€"29, 2019, in Washington, DC. This workshop examined social determinants of health (SDOH) in the context of cancer, and considered opportunities to effectively leverage big data to improve health equity and reduce disparities. The workshop featured presentations and discussion by experts in technology, oncology, and SDOH, as well as representatives from government, industry, academia, and health care systems. This publication summarizes the presentations and discussions from the workshop.

Me Medicine Vs. We Medicine

Author : Donna Dickenson
Publisher :
ISBN 13 : 9780231159753
Total Pages : 0 pages
Book Rating : 4.1/5 (597 download)

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Book Synopsis Me Medicine Vs. We Medicine by : Donna Dickenson

Download or read book Me Medicine Vs. We Medicine written by Donna Dickenson and published by . This book was released on 2016-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized healthcare--or what the award-winning author Donna Dickenson calls "Me Medicine"--is radically transforming our longstanding "one-size-fits-all" model. Technologies such as direct-to-consumer genetic testing, pharmacogenetically developed therapies in cancer care, private umbilical cord blood banking, and neurocognitive enhancement claim to cater to an individual's specific biological character, and, in some cases, these technologies have shown powerful potential. Yet in others they have produced negligible or even negative results. Whatever is behind the rise of Me Medicine, it isn't just science. So why is Me Medicine rapidly edging out We Medicine, and how has our commitment to our collective health suffered as a result? In her cogent, provocative analysis, Dickenson examines the economic and political factors fueling the Me Medicine phenomenon and explores how, over time, this paradigm shift in how we approach our health might damage our individual and collective well-being. Historically, the measures of "We Medicine," such as vaccination and investment in public-health infrastructure, have radically extended our life spans, and Dickenson argues we've lost sight of that truth in our enthusiasm for "Me Medicine." Dickenson explores how personalized medicine illustrates capitalism's protean capacity for creating new products and markets where none existed before--and how this, rather than scientific plausibility, goes a long way toward explaining private umbilical cord blood banks and retail genetics. Drawing on the latest findings from leading scientists, social scientists, and political analysts, she critically examines four possible hypotheses driving our Me Medicine moment: a growing sense of threat; a wave of patient narcissism; corporate interests driving new niche markets; and the dominance of personal choice as a cultural value. She concludes with insights from political theory that emphasize a conception of the commons and the steps we can take to restore its value to modern biotechnology.