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Author : Andreas Martin Seitz
Publisher : Frontiers Media SA
ISBN 13 : 2889760197
Total Pages : 141 pages
Book Rating : 4.8/5 (897 download)
Download or read book Post-Traumatic Osteoarthritis After Meniscus Injury written by Andreas Martin Seitz and published by Frontiers Media SA. This book was released on 2022-04-28 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Steven A. Olson, MD
Publisher : Springer
ISBN 13 : 148997606X
Total Pages : 362 pages
Book Rating : 4.4/5 (899 download)
Download or read book Post-Traumatic Arthritis written by Steven A. Olson, MD and published by Springer. This book was released on 2015-06-29 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.
Author : Ian Lodge Roberts
Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (957 download)
Download or read book Novel Biomechanical and Biochemical Signatures of Post-Traumatic Osteoarthritis written by Ian Lodge Roberts and published by . This book was released on 2016 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post-traumatic osteoarthritis (PTOA) is an inflammatory-based cartilage degenerating disease that develops after joint injury. It results in the breakdown of articular cartilage in the joints, leading to pain and loss of mobility over time, eventually requiring surgical intervention. Approximately 50% of patients who suffer a serious joint injury such as an anterior cruciate ligament (ACL) tear will develop diagnosable PTOA within 10-15 years. In the United States, more than 5 million people have various degrees of PTOA in the hip, ankle, or knee. Despite its prevalence, there are few treatments for cartilage injury, with most medical intervention centered around palliative care once PTOA has been diagnosed. Pharmacological solutions are limited, due to the complexity and difficulty of studying chondrocyte behavior and the cartilage matrix structure-function relationship in vivo. In this study, cartilage injury was induced in a murine model by the destabilization of the medial meniscus (DMM) surgery on the right knee joint. After the procedure, chondrocyte signaling behavior was studied by examining the expression of bone morphogenetic protein-2 (BMP2) and its associated intracellular downstream mediator, pSmad1/5/8, using immunohistochemistry. These two proteins are important homeostatic cytokines in cartilage, instructing chondrocytes to synthesize new extra-cellular matrix (ECM), mainly type II collagen and aggrecan. Changes in the matrix structure of cartilage were examined via changes in aggrecan and decorin. Aggrecan is a large, highly charged protein that binds to water, reducing its flow, and giving cartilage its innate force-cushioning properties. Decorin is an important, small leucine-rich proteoglycan, which regulates the formation and homeostasis of cartilage ECM through binding to other proteoglycans, such as aggrecan. In addition, changes in function-relevant mechanical properties were also examined by atomic force microscopy (AFM)-based Nanoindentation on condyle cartilage surfaces. After the DMM surgery, cartilage homeostasis was disrupted. BMP2 and pSmad1/5/8 staining increased, suggesting anabolic and catabolic changes to chondrocyte function. Aggrecan concentration was reduced, signifying degradation of the ECM. Meanwhile, the active involvement of decorin in the ECM degradation process is indicated by the substantial reduction of aggrecan in decorin-null mice. Furthermore, cartilage after DMM showed significantly lower nanoindentation modulus than the control after Sham surgery, highlighting OA-induced loss of joint function. These biochemical and biomechanical results prove insights into the concomitant biological and biomechanical changes of cartilage during the progression of injury-induced PTOA.
Author : Christian Lattermann
Publisher : Springer Nature
ISBN 13 : 3030794857
Total Pages : 335 pages
Book Rating : 4.0/5 (37 download)
Download or read book Early Osteoarthritis written by Christian Lattermann and published by Springer Nature. This book was released on 2021-10-09 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the joint surface or ligamentous stability is not sufficient to restore the homeostatic environment in the joint, and this leads to osteoarthritis, despite mechanical stability and alignment. This book sheds light on the various mechanisms and systems involved in the gradual decline of the injured joint toward manifest osteoarthritis. Published in collaboration with ISAKOS, this volume appeals to all stakeholders in surgical orthopaedics and sports medicine.
Author : Beth A. Winkelstein
Publisher : CRC Press
ISBN 13 : 1439860947
Total Pages : 637 pages
Book Rating : 4.4/5 (398 download)
Download or read book Orthopaedic Biomechanics written by Beth A. Winkelstein and published by CRC Press. This book was released on 2012-12-18 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review o
Author : James Alan Rand
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)
Download or read book Total Knee Arthroplasty written by James Alan Rand and published by Lippincott Williams & Wilkins. This book was released on 1993 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference on total knee arthroplasty describes all surgical techniques and prosthetic designs for primary and revision arthroplasty, discusses every aspect of patient selection, preoperative planning, and intraoperative and postoperative care.
Author : Sadegh Khodabandeloo
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)
Download or read book Biomechanical Outcomes 1 Year After Acl Reconstruction and Meniscus Surgery written by Sadegh Khodabandeloo and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post-traumatic osteoarthritis (PTOA) is a long-term outcome following anterior cruciate ligament reconstruction (ACLR) surgery. PTOA is defined by pain limitations during movement and the degeneration of articular cartilage. This study aimed to investigate side-to-side differences in arthrokinematics and quantitative magnetic resonance imaging (qMRI) in patients who underwent ACLR with meniscal surgery. Nine participants who had undergone ACLR surgery with meniscal repair and/or partial meniscectomy were included in this study. Arthrokinematic analysis was performed during walking and jogging activities. qMRI measurements, including T1[rho] and T2* relaxation times, were assessed to evaluate cartilage composition. qMRI measurements were acquired with patients laying supine in the MR scanner without an external load applied, as is performed normally, and while a MR-compatible device applied an axial load equivalent to 50% of body weight. The results showed posterior shifts in contact locations during walking, increased cartilage overlap during walking and jogging, and higher sliding velocities in the posterior direction in the injured knee compared to the uninjured knee. The qMRI analysis revealed increased T1[rho], decreased loaded T2* relaxation times and the higher effect of load in the injured knees. These findings contribute to our understanding of the effects of ACLR surgery on arthrokinematics and cartilage composition.
Author : Philippe Beaufils
Publisher : Springer Science & Business Media
ISBN 13 : 3642024505
Total Pages : 397 pages
Book Rating : 4.6/5 (42 download)
Download or read book The Meniscus written by Philippe Beaufils and published by Springer Science & Business Media. This book was released on 2010-04-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide focuses on the normal meniscal mechanism, body and function. Meniscal pathology and therapy are depicted in detail, followed by a presentation of long-term experience of meniscal transplantation and a look into the future of meniscal surgery.
Author : Jack Farr
Publisher : Springer Science & Business Media
ISBN 13 : 1461404274
Total Pages : 251 pages
Book Rating : 4.4/5 (614 download)
Download or read book Cartilage Restoration written by Jack Farr and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attempting to bridge the gap between the science and art of cartilage restoration, Cartilage Restoration: Practical Clinical Applications combines an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. With chapters written by internationally-renowned orthopedic surgeons, topics include an overview of current surgical options, debridement and marrow stimulation, autograft plug transfer, allografts, cell therapy, and meniscal issues. Cartilage Restoration is a valuable resource for orthopedic surgeons, residents, and fellows.
Author : Savyasachi C. Thakkar
Publisher : Springer Nature
ISBN 13 : 3030504131
Total Pages : 223 pages
Book Rating : 4.0/5 (35 download)
Download or read book Post-Traumatic Arthritis written by Savyasachi C. Thakkar and published by Springer Nature. This book was released on 2020-09-30 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence and prevalence of post-traumatic arthritis (PTA) is increasing globally due to longevity of life and increased activity and injuries. Compared to the non-traumatic etiology of arthritis, post-traumatic arthritis differs in presentation, severity and complexity of management. This book illustrates all pertinent facets of post-traumatic arthritis, from the basic science and diagnostic modalities to their management and outcomes. The opening section reviews the current scientific literature on PTA and presents the preferred imaging techniques and interpretation methods. A unique chapter on the economic impact of PTA is also included here. The subsequent two sections discuss both the upper and lower extremity, respectively, with each joint covered in a dedicated chapter of its own, describing the mechanisms of injury, assessment, management strategies and outcomes. Case material provides real-world context for the concepts and techniques presented, supported by generous radiology and intraoperative photos and figures. With Post-Traumatic Arthritis, orthopedic surgeons, as well as trauma surgeons, rheumatologists and associated clinical staff, will receive a comprehensive framework on which to base their clinical decisions and enhance their post-operative outcomes.
Author : Ali Guermazi
Publisher : Clinics: Internal Medicine
ISBN 13 : 9781437717501
Total Pages : 0 pages
Book Rating : 4.7/5 (175 download)
Download or read book State of the Art Imaging of Osteoarthritis written by Ali Guermazi and published by Clinics: Internal Medicine. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue takes a multimodality approach to imaging of osteoarthritis. Clinical issues including an overview of the disease and imaging as an aid to evaluate patient functionality are also reviewed. Not only are current standards for imaging covered, but also newer techniques under development.
Author : Christophe Hulet
Publisher : Springer
ISBN 13 : 3662491885
Total Pages : 565 pages
Book Rating : 4.6/5 (624 download)
Download or read book Surgery of the Meniscus written by Christophe Hulet and published by Springer. This book was released on 2016-03-29 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, published in cooperation with ESSKA, provides an exhaustive review of the meniscus and its pathology, covering all aspects from the basic science of the normal meniscus to clinical and imaging diagnosis, meniscus repair and meniscectomy, outcomes and complications, postoperative management, and emerging technologies. The book opens by examining in depth aspects such as anatomy, histology, physiology, biomechanics, and physiopathology. Clear guidance is offered on arthroscopy and the classification of meniscal lesions, with consideration of the full range of meniscal pathology, including traumatic lesions, degenerative lesions, root tears, meniscal cysts, and congenital lesions. Choice of treatment in different settings is explained, and the various surgical techniques – meniscectomy, meniscal repair, and reconstruction with allografts – are described in detail with the aid of accompanying videos and with presentation of long-term results. The concluding chapter takes a look into the future of meniscus reconstruction, for example through regeneration using mesenchymal stem cells.
Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 3030712818
Total Pages : 293 pages
Book Rating : 4.0/5 (37 download)
Download or read book Musculoskeletal Diseases 2021-2024 written by Juerg Hodler and published by Springer Nature. This book was released on 2021 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.
Author : Michel Bonnin
Publisher : Springer Science & Business Media
ISBN 13 : 2287993533
Total Pages : 1027 pages
Book Rating : 4.2/5 (879 download)
Download or read book The Knee Joint written by Michel Bonnin and published by Springer Science & Business Media. This book was released on 2013-07-04 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pushed by the progress of biology, technology and biomechanics, knee surgery has dramatically evolved in the last decades. This book is a "state of the art" concerning all aspects of knee surgery from ligament reconstruction to Total Knee Arthroplasty. An international panel of renowned authors have worked on this didactic fully illustrated book. It will help young surgeons to understand basic sciences and modern sugical techniques. The experienced surgeon will find help to deal with difficult cases and clarifications in recent technologic advances such as cartilage surgery, navigation and mini invasive surgery.
Author : James M. Fox
Publisher : McGraw-Hill Professional Publishing
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Patellofemoral Joint written by James M. Fox and published by McGraw-Hill Professional Publishing. This book was released on 1993 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul A. Banaszkiewicz
Publisher : Cambridge University Press
ISBN 13 : 1107627362
Total Pages : 301 pages
Book Rating : 4.1/5 (76 download)
Download or read book Postgraduate Orthopaedics written by Paul A. Banaszkiewicz and published by Cambridge University Press. This book was released on 2012-08-16 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).
Author : Mahmut Nedim Doral
Publisher : Springer Nature
ISBN 13 : 3642365698
Total Pages : 3295 pages
Book Rating : 4.6/5 (423 download)
Download or read book Sports Injuries written by Mahmut Nedim Doral and published by Springer Nature. This book was released on 2015-06-29 with total page 3295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.
