Pocket Guide To Biomolecular Nmr

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Pocket Guide to Biomolecular NMR

Author : Michaeleen Doucleff
Publisher : Springer Science & Business Media
ISBN 13 : 3642162517
Total Pages : 166 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Pocket Guide to Biomolecular NMR by : Michaeleen Doucleff

Download or read book Pocket Guide to Biomolecular NMR written by Michaeleen Doucleff and published by Springer Science & Business Media. This book was released on 2011-01-03 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steering clear of quantum mechanics and product operators, "Pocket Guide to Biomolecular NMR" uses intuitive, concrete analogies to explain the theory required to understand NMR studies on the structure and dynamics of biological macromolecules. For example, instead of explaining nuclear spin with angular momentum equations or Hamiltonians, the books describes nuclei as "bells" in a choir, ringing at specific frequencies depending on the atom type and their surrounding electromagnetic environment.This simple bell analogy, which is employed throughout the book, has never been used to explain NMR and makes it surprisingly easy to learn complex, bewildering NMR concepts, such as dipole-dipole coupling and CPMG pulse sequences. Other topics covered include the basics of multi-dimensional NMR, relaxation theory, and Model Free analysis. The small size and fast pace of “Pocket Guide to Biomolecular NMR” makes the book a perfect companion to traditional biophysics and biochemistry textbooks, but the book's unique perspective will provide even seasoned spectroscopists with new insights and handy “thought” short-cuts.

Biomolecular NMR Spectroscopy

Author : Andrew J. Dingley
Publisher : IOS Press
ISBN 13 : 1607506947
Total Pages : 488 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Biomolecular NMR Spectroscopy by : Andrew J. Dingley

Download or read book Biomolecular NMR Spectroscopy written by Andrew J. Dingley and published by IOS Press. This book was released on 2011 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

NMR in Biological Systems

Author : K.V.R. Chary
Publisher : Springer Science & Business Media
ISBN 13 : 1402066805
Total Pages : 552 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis NMR in Biological Systems by : K.V.R. Chary

Download or read book NMR in Biological Systems written by K.V.R. Chary and published by Springer Science & Business Media. This book was released on 2008-04-01 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.

Recent Developments in Biomolecular NMR

Author : Marius Clore
Publisher : Royal Society of Chemistry
ISBN 13 : 1849735395
Total Pages : 250 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Recent Developments in Biomolecular NMR by : Marius Clore

Download or read book Recent Developments in Biomolecular NMR written by Marius Clore and published by Royal Society of Chemistry. This book was released on 2012-08-21 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy is widely used in biomolecular science particularly for structure determination of proteins, nucleic acids and carbohydrates. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an important technique in structural biology. Filling a gap in the literature, this book draws together experts in the field to discuss the real advances in NMR methods that have occurred or have an impact on the biomolecular field in the last few years. The coverage includes recent developments in using NMR for determination of protein structures, membrane proteins, the dynamics of RNA and advances in NMR in drug discovery. Edited by leading biological NMR spectroscopists, the book is essential reference for researchers in industry and academia interested in or joining this bioanalytical field.

NMR of Biomolecules

Author : Ivano Bertini
Publisher : John Wiley & Sons
ISBN 13 : 3527328505
Total Pages : 15 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis NMR of Biomolecules by : Ivano Bertini

Download or read book NMR of Biomolecules written by Ivano Bertini and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.

Fundamentals of Protein NMR Spectroscopy

Author : Gordon S. Rule
Publisher : Springer Science & Business Media
ISBN 13 : 1402034997
Total Pages : 543 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Fundamentals of Protein NMR Spectroscopy by : Gordon S. Rule

Download or read book Fundamentals of Protein NMR Spectroscopy written by Gordon S. Rule and published by Springer Science & Business Media. This book was released on 2005-10-28 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.

Isotope labeling in Biomolecular NMR

Author : Hanudatta S. Atreya
Publisher : Springer Science & Business Media
ISBN 13 : 9400749546
Total Pages : 219 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Isotope labeling in Biomolecular NMR by : Hanudatta S. Atreya

Download or read book Isotope labeling in Biomolecular NMR written by Hanudatta S. Atreya and published by Springer Science & Business Media. This book was released on 2012-10-18 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Paramagnetism in Experimental Biomolecular NMR

Author : Enrico Ravera
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010868
Total Pages : 340 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Paramagnetism in Experimental Biomolecular NMR by : Enrico Ravera

Download or read book Paramagnetism in Experimental Biomolecular NMR written by Enrico Ravera and published by Royal Society of Chemistry. This book was released on 2018-08-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paramagnetic NMR is a growing technique that represents an increasingly important tool for the investigation of biomolecules. This book presents an update and overview of the paramagnetic NMR phenomena and effects as well as guidelines for practical implementation of state-of-the-art experiments. All experiments are supported by a solid theoretical foundation. Areas mentioned are the development of solid state NMR, the use of paramagnetic tags providing information on the structure and mobility of the investigated systems, and dynamic nuclear polarization to increase sensitivity. Compiled by experts in the field, this book has international appeal for researchers as well as students interested in magnetic resonance and structural biology who require experimental support and accessible information.

NMR for Chemists and Biologists

Author : Rodrigo J Carbajo
Publisher : Springer Science & Business Media
ISBN 13 : 9400769768
Total Pages : 125 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis NMR for Chemists and Biologists by : Rodrigo J Carbajo

Download or read book NMR for Chemists and Biologists written by Rodrigo J Carbajo and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intends to be an easy and concise introduction to the field of nuclear magnetic resonance or NMR, which has revolutionized life sciences in the last twenty years. A significant part of the progress observed in scientific areas like Chemistry, Biology or Medicine can be ascribed to the development experienced by NMR in recent times. Many of the books currently available on NMR deal with the theoretical basis and some of its main applications, but they generally demand a strong background in Physics and Mathematics for a full understanding. This book is aimed to a wide scientific audience, trying to introduce NMR by making all possible effort to remove, without losing any formality and rigor, most of the theoretical jargon that is present in other NMR books. Furthermore, illustrations are provided that show all the basic concepts using a naive vector formalism, or using a simplified approach to the particular NMR-technique described. The intention has been to show simply the foundations and main concepts of NMR, rather than seeking thorough mathematical expressions.

Biomolecular NMR Spectroscopy

Author : Jeremy N. S. Evans
Publisher : Oxford University Press, USA
ISBN 13 : 9780198547662
Total Pages : 444 pages
Book Rating : 4.5/5 (476 download)

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Book Synopsis Biomolecular NMR Spectroscopy by : Jeremy N. S. Evans

Download or read book Biomolecular NMR Spectroscopy written by Jeremy N. S. Evans and published by Oxford University Press, USA. This book was released on 1995 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The technique of nuclear magnetic resonance (NMR) spectroscopy is an important tool in biochemistry and biophysics for the understanding of the structure and ultimately, the function of biomolecules. This textbook explains the salient features of biological NMR spectroscopy to undergraduates and postgraduates taking courses in NMR, biological NMR, physical biochemistry, and biophysics. Unlike other books in the general field of NMR (except the advanced treatises), the approach here is tointroduce and make use of quantum mechanical product operators as well as the classical vector method of explaining the bewildering array of pulse sequences available today. The book covers two- dimensional, three- dimensional, and four- dimensional NMR and their application to protein and DNA structure determination. A unique feature is the coverage of the biological aspects of solid- state NMR spectroscopy. The author provides many selected examples from the research literature, illustratingthe applications of NMR spectroscopy to biological proteins.

Biological NMR

Author : A.Joshua Wand
Publisher : Academic Press
ISBN 13 : 0128138610
Total Pages : 440 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biological NMR by : A.Joshua Wand

Download or read book Biological NMR written by A.Joshua Wand and published by Academic Press. This book was released on 2019-01-03 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs and micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, Structure determination and computer analysis, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods of Enzymology series Updated release includes the latest information on the Biological NMR

Understanding NMR Spectroscopy

Author : James Keeler
Publisher : Wiley
ISBN 13 : 9780470017869
Total Pages : 476 pages
Book Rating : 4.0/5 (178 download)

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Book Synopsis Understanding NMR Spectroscopy by : James Keeler

Download or read book Understanding NMR Spectroscopy written by James Keeler and published by Wiley. This book was released on 2005-12-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding NMR Spectroscopy James Keeler Department of Chemistry, University of Cambridge, UK This text discusses the high-resolution NMR of liquid samples and concentrates exclusively on spin-half nuclei (mainly 1H and 13C). It is aimed at people who are familiar with the use of routine NMR for structure determination and who wish to deepen their understanding of just exactly how NMR experiments work. It demonstrates that in NMR it is possible, quite literally on the back of an envelope, to make exact predictions of the outcome of quite sophisticated experiments. The experiments chosen are likely to be encountered in the routine NMR of small to medium-sized molecules, but are also applicable to the study of large biomolecules, such as proteins and nucleic acids. The book starts off at a gentle pace, working through some more-or-less familiar ideas, and then elaborating these as the book progresses. Each chapter ends with exercises which are designed to assist in the understanding of the ideas presented and to grasp the underlying ideas.

Characterization of Biological Membranes

Author : Mu-Ping Nieh
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110544652
Total Pages : 647 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Characterization of Biological Membranes by : Mu-Ping Nieh

Download or read book Characterization of Biological Membranes written by Mu-Ping Nieh and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes. The current book is an excellent introduction to the area, which explains how modern analytical methods can be applied to study biological membranes and membrane proteins and the bioprocesses they are involved to.

Protein NMR Spectroscopy

Author : John Cavanagh
Publisher : Elsevier
ISBN 13 : 008047103X
Total Pages : 915 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Protein NMR Spectroscopy by : John Cavanagh

Download or read book Protein NMR Spectroscopy written by John Cavanagh and published by Elsevier. This book was released on 2010-07-21 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein NMR Spectroscopy, Second Edition combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments. Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced. The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field. Provides an understanding of the theoretical principles important for biological NMR spectroscopy Demonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments Allows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics Includes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods

NMR and Chemistry

Author : J.W. Akitt
Publisher : CRC Press
ISBN 13 : 9780748743445
Total Pages : 422 pages
Book Rating : 4.7/5 (434 download)

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Book Synopsis NMR and Chemistry by : J.W. Akitt

Download or read book NMR and Chemistry written by J.W. Akitt and published by CRC Press. This book was released on 2000-02-17 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keeping mathematics to a minimum, this book introduces nuclear properties, nuclear screening, chemical shift, spin-spin coupling, and relaxation. It is one of the few books that provides the student with the physical background to NMR spectroscopy from the point of view of the whole of the periodic table rather than concentrating on the narrow applications of 1H and 13C NMR spectroscopy. Aids to structure determination, such as decoupling, the nuclear Overhauser effect, INEPT, DEPT, and special editing, and two dimensional NMR spectroscopy are discussed in detail with examples, including the complete assignment of the 1H and 13C NMR spectra of D-amygdain. The authors examine the requirements of a modern spectrometer and the effects of pulses and discuss the effects of dynamic processes as a function of temperature or pressure on NMR spectra. The book concludes with chapters on some of the applications of NMR spectroscopy to medical and non-medical imaging techniques and solid state chemistry of both I = F1/2 and I > F1/2 nuclei. Examples and problems, mainly from the recent inorganic/organometallic chemistry literature support the text throughout. Brief answers to all the problems are provided in the text with full answers at the end of the book.

Isotope labeling in Biomolecular NMR

Author : Hanudatta S. Atreya
Publisher : Springer
ISBN 13 : 9789400749559
Total Pages : 219 pages
Book Rating : 4.7/5 (495 download)

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Book Synopsis Isotope labeling in Biomolecular NMR by : Hanudatta S. Atreya

Download or read book Isotope labeling in Biomolecular NMR written by Hanudatta S. Atreya and published by Springer. This book was released on 2012-10-18 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Dynamics and Kinetics in Structural Biology

Author : Keith Moffat
Publisher : John Wiley & Sons
ISBN 13 : 1119696283
Total Pages : 292 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Dynamics and Kinetics in Structural Biology by : Keith Moffat

Download or read book Dynamics and Kinetics in Structural Biology written by Keith Moffat and published by John Wiley & Sons. This book was released on 2024-01-03 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the latest experimental tools in structural biology with this pioneering work Structural biology seeks to understand the chemical mechanisms and functions of biological molecules, such as proteins, based on their atomic structures. Until recently, these structures have been studied only statically, using procedures which deliberately freeze atomic motion. However, freezing eliminates the rapid structural motions so essential to biological activity and function; the molecules are inactive. But with the recent development of X-ray free electron laser (XFEL) sources, efforts to conduct dynamic experiments have expanded using the principles of dynamics and kinetics to capture active biological molecules as they function. Dynamics and Kinetics in Structural Biology promotes the development of these experiments and their successful application. It grounds readers in the foundational principles of dynamics and kinetics; proceeds through extended discussions of experimental procedures, data analysis techniques; and explores experimental frontiers in structural dynamics. The book will aid researchers to gather and interpret cutting-edge data on the dynamic structure of biological molecules, under conditions where they retain their biological functions. Dynamics and Kinetics in Structural Biology offers readers: Authorship by founding figures in the field In-depth presentation of time-resolved X-ray crystallography, solution scattering, and more A pioneering contribution to a rapidly developing field of study Dynamics and Kinetics in Structural Biology is essential reading for graduate students, scientists, researchers and industry professionals engaged in structural studies of biological systems. Industry professionals considering dynamic studies in the development of new product lines will also benefit.