Plga Based Drug Carrier And Pharmaceutical Applications

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PLGA Based Drug Carrier and Pharmaceutical Applications

Author : Maria Carmo Pereira
Publisher : MDPI
ISBN 13 : 3036502203
Total Pages : 328 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis PLGA Based Drug Carrier and Pharmaceutical Applications by : Maria Carmo Pereira

Download or read book PLGA Based Drug Carrier and Pharmaceutical Applications written by Maria Carmo Pereira and published by MDPI. This book was released on 2021-03-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers used for producing therapeutic devices, such as drug carriers (DC). PLGA is one of the few polymers that the Food and Drug Administration (FDA) has approved for human administration due to its biocompatibility and biodegradability. In recent years, DC produced with PLGA has gained enormous attention for its versatility in transporting different type of drugs, e.g., hydrophilic or hydrophobic small molecules, or macromolecules with a controlled drug release without modifying the physiochemical properties of the drugs. These drug delivery systems have the possibility/potential to modify their surface properties with functional groups, peptides, or other coatings to improve the interactions with biological materials. Furthermore, they present the possibility to be conjugated with specific target molecules to reach specific tissues or cells. They are also used for different therapeutic applications, such as in vaccinations, cancer treatment, neurological disorder treatment, and as anti-inflammatory agents. This book aims to focus on the recent progress of PLGA as a drug carrier and their new pharmaceutical applications.

PLGA Based Drug Carrier and Pharmaceutical Applications

Author : Maria Carmo Pereira
Publisher :
ISBN 13 : 9783036502212
Total Pages : 328 pages
Book Rating : 4.5/5 (22 download)

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Book Synopsis PLGA Based Drug Carrier and Pharmaceutical Applications by : Maria Carmo Pereira

Download or read book PLGA Based Drug Carrier and Pharmaceutical Applications written by Maria Carmo Pereira and published by . This book was released on 2021 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers used for producing therapeutic devices, such as drug carriers (DC). PLGA is one of the few polymers that the Food and Drug Administration (FDA) has approved for human administration due to its biocompatibility and biodegradability. In recent years, DC produced with PLGA has gained enormous attention for its versatility in transporting different type of drugs, e.g., hydrophilic or hydrophobic small molecules, or macromolecules with a controlled drug release without modifying the physiochemical properties of the drugs. These drug delivery systems have the possibility/potential to modify their surface properties with functional groups, peptides, or other coatings to improve the interactions with biological materials. Furthermore, they present the possibility to be conjugated with specific target molecules to reach specific tissues or cells. They are also used for different therapeutic applications, such as in vaccinations, cancer treatment, neurological disorder treatment, and as anti-inflammatory agents. This book aims to focus on the recent progress of PLGA as a drug carrier and their new pharmaceutical applications.

Pharmaceutical Applications of Polymers for Drug Delivery

Author : David Jones
Publisher : iSmithers Rapra Publishing
ISBN 13 : 9781859574799
Total Pages : 138 pages
Book Rating : 4.5/5 (747 download)

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Book Synopsis Pharmaceutical Applications of Polymers for Drug Delivery by : David Jones

Download or read book Pharmaceutical Applications of Polymers for Drug Delivery written by David Jones and published by iSmithers Rapra Publishing. This book was released on 2004 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The review focuses on the use of pharmaceutical polymer for controlled drug delivery applications. Examples of pharmaceutical polymers and the principles of controlled drug delivery are outlined and applications of polymers for controlled drug delivery are described. The field of controlled drug delivery is vast therefore this review aims to provide an overview of the applications of pharmaceutical polymers. The review is accompanied by approximately 250 abstracts taken from papers and books in the Rapra Polymer Library database, to facilitate further reading on this subject.

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Applications of Polymers in Drug Delivery by : Ambikanandan Misra

Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Drug Delivery

Author : Prashant Kesharwani
Publisher : Elsevier
ISBN 13 : 032391215X
Total Pages : 532 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Drug Delivery by : Prashant Kesharwani

Download or read book Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Drug Delivery written by Prashant Kesharwani and published by Elsevier. This book was released on 2023-03 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail. The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials.

The Blood Brain Barrier (BBB)

Author : Gert Fricker
Publisher : Springer
ISBN 13 : 3662437872
Total Pages : 169 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis The Blood Brain Barrier (BBB) by : Gert Fricker

Download or read book The Blood Brain Barrier (BBB) written by Gert Fricker and published by Springer. This book was released on 2014-10-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Handbook of Polymers for Pharmaceutical Technologies, Processing and Applications

Author : Vijay Kumar Thakur
Publisher : John Wiley & Sons
ISBN 13 : 1119041406
Total Pages : 496 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Handbook of Polymers for Pharmaceutical Technologies, Processing and Applications by : Vijay Kumar Thakur

Download or read book Handbook of Polymers for Pharmaceutical Technologies, Processing and Applications written by Vijay Kumar Thakur and published by John Wiley & Sons. This book was released on 2015-07-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Fundamentals and Applications of Controlled Release Drug Delivery

Author : Juergen Siepmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461408806
Total Pages : 593 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Fundamentals and Applications of Controlled Release Drug Delivery by : Juergen Siepmann

Download or read book Fundamentals and Applications of Controlled Release Drug Delivery written by Juergen Siepmann and published by Springer Science & Business Media. This book was released on 2011-12-14 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pitched at a level comprehensible to those new to the field, this authoritative text covers the scientific and technological fundamentals of drug delivery as well as clinical applications and the developmental potential in controlled release drug delivery.

Silk-based Drug Delivery Systems

Author : Elia Bari
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017722
Total Pages : 243 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Silk-based Drug Delivery Systems by : Elia Bari

Download or read book Silk-based Drug Delivery Systems written by Elia Bari and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Nanoparticulates as Drug Carriers

Author : Vladimir P Torchilin
Publisher : World Scientific
ISBN 13 : 1908979976
Total Pages : 756 pages
Book Rating : 4.9/5 (89 download)

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Book Synopsis Nanoparticulates as Drug Carriers by : Vladimir P Torchilin

Download or read book Nanoparticulates as Drug Carriers written by Vladimir P Torchilin and published by World Scientific. This book was released on 2006-09-29 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Contents:Nanoparticle Flow: Implications for Drug Delivery (A T Florence)Polymer Micelles as Drug Carriers (E V Batrakova et al.)Lipoproteins as Pharmaceutical Carriers (S Liu et al.)Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia)Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero)Magnetic Nanoparticles as Drug Carriers (U O Häfeli & M Chastellain)Liposomal Drug Carriers in Cancer Therapy (A A Gabizon)Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw)Nanoparticles for Targeting Lymphatics (W Phillips)Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso)and other papers Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging. Keywords:Drug Delivery;Drug Targeting;Drug Carriers;Nanomedicine;Nanotechnology;Pharmaceutical Biotechnology;Experimental TherapyKey Features:Chapters are written by leading scientists such as Prof Gregoriadis, Prof Moghimi, Prof Kabanov, Prof Tomalia, Prof Couvreur, Prof Mueller, Prof Gabizon and Prof Kreuter

Delivery of Drugs

Author : Ranjita Shegokar
Publisher : Elsevier
ISBN 13 : 0128177772
Total Pages : 242 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Delivery of Drugs by : Ranjita Shegokar

Download or read book Delivery of Drugs written by Ranjita Shegokar and published by Elsevier. This book was released on 2020-02-01 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems, Volume Two examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects. This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders. This level of discussion makes it a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about the status of drug delivery systems. Delivery of Drugs examines the fabrication, optimization, scale-up, biological aspects, regulatory and clinical success of various micro and nano drug delivery systems. The volume covers site and organ specific targeting approaches, technologies used in preparation of micro - nanoparticles, challenges of complex type of drug delivery forms and role of physical methods in achieving targeted drug effect. Written by a diverse range of international researchers the chapters examine the specific aspects of characterization and manufacturing of drug delivery system for pharmaceutical application and its regulatory aspects. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

Handbook of Polyester Drug Delivery Systems

Author : M. N. V. Ravi Kumar
Publisher : CRC Press
ISBN 13 : 1315341166
Total Pages : 401 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Polyester Drug Delivery Systems by : M. N. V. Ravi Kumar

Download or read book Handbook of Polyester Drug Delivery Systems written by M. N. V. Ravi Kumar and published by CRC Press. This book was released on 2017-03-27 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.

Bio-inspired Polymers

Author : Nico Bruns
Publisher : Royal Society of Chemistry
ISBN 13 : 1782626662
Total Pages : 612 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Bio-inspired Polymers by : Nico Bruns

Download or read book Bio-inspired Polymers written by Nico Bruns and published by Royal Society of Chemistry. This book was released on 2016-10-14 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many key aspects of life are based on naturally occurring polymers, such as polysaccharides, proteins and DNA. Unsurprisingly, their molecular functionalities, macromolecular structures and material properties are providing inspiration for designing new polymeric materials with specific functions, for example, responsive, adaptive and self-healing materials. Bio-inspired Polymers covers all aspects of the subject, ranging from the synthesis of novel polymers, to structure-property relationships, materials with advanced properties and applications of bio-inspired polymers in such diverse fields as drug delivery, tissue engineering, optical materials and lightweight structural materials. Written and edited by leading experts on the topic, the book provides a comprehensive review and essential graduate level text on bio-inspired polymers for biochemists, materials scientists and chemists working in both industry and academia.

Pharmaceutical Dosage Forms and Drug Delivery

Author : Ram I. Mahato
Publisher : CRC Press
ISBN 13 : 1420009206
Total Pages : 334 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Pharmaceutical Dosage Forms and Drug Delivery by : Ram I. Mahato

Download or read book Pharmaceutical Dosage Forms and Drug Delivery written by Ram I. Mahato and published by CRC Press. This book was released on 2007-06-07 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating aspects of physical pharmacy, biopharmaceuticals, drug delivery, and biotechnology, Pharmaceutical Dosage Forms and Drug Delivery elucidates basic physicochemical principles and their application in the design of dosage forms. The author addresses the relevance of these principles to the biopharmaceutical aspects of drugs. He explores the latest developments in the application of biomaterials, including polymers and biotechnology-based agents, to the development of novel dosage forms. The book covers physicochemical principles of dosage design, biopharmaceutical and physiological considerations, types of commonly used pharmaceutical dosage forms, introduction to polymeric biomaterials, protein and nucleic acid-based dosage forms, and novel and targeted drug delivery systems. It highlights the physicochemical parameters used for the design, development, and evaluation of biotechnological dosage forms and describes the biological barriers to drug absorption. Containing the right blend of mathematics, equations, diagrams, pictorials, and other pertinent information, this book provides a unified perspective that creates a greater overall understanding of basic science and cutting-edge technology.

Nanoparticulate Drug Delivery Systems

Author : Deepak Thassu
Publisher : CRC Press
ISBN 13 : 1000654745
Total Pages : 345 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanoparticulate Drug Delivery Systems by : Deepak Thassu

Download or read book Nanoparticulate Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2007-03-30 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.7/5 (253 download)

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Book Synopsis Polymeric Drug Delivery Systems by : Glen S. Kwon

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Advanced Drug Delivery

Author : Ashim Mitra
Publisher : John Wiley & Sons
ISBN 13 : 1118662849
Total Pages : 844 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Advanced Drug Delivery by : Ashim Mitra

Download or read book Advanced Drug Delivery written by Ashim Mitra and published by John Wiley & Sons. This book was released on 2013-08-26 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.