The Hypothalamus-Pituitary-Adrenal Axis

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Author :
Publisher : Elsevier
ISBN 13 : 0080559360
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Hypothalamus-Pituitary-Adrenal Axis by :

Download or read book The Hypothalamus-Pituitary-Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later

Central Regulation of the Pituitary-Adrenal Complex

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468416146
Total Pages : 200 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Central Regulation of the Pituitary-Adrenal Complex by : E. V. Naumenko

Download or read book Central Regulation of the Pituitary-Adrenal Complex written by E. V. Naumenko and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph gives an up-to-date account of the original results of the author's research in the complex field of the central control over relationships which have become established in the course of evolution between the hypothalamus and the pituitary gland. The author has limited the scope of this research on logical grounds to the study of central chemically reactive structures in the regulation of the adrenal glands through the intermediary of the hypothalamo-hypophyseal system. Through the author's skill and expertise in the analysis of the extensive and sometimes complicated literature he has successfully undertaken a differential approach to the analysis of the concrete role of catecholamines, acetylcholine, and serotonin in relation to the endocrine system. The vast range of experimental investigations and results of clinical observations published in the last few decades have revealed the humoral neurosecretory factors of the hypothalamus as impor tant regulators of the princ ipal functions of the pituitary gland and, through it, of the cyclic activity of the peripheral group of endocrine glands. Until recently the region of the cascade of regulatory in fluences preceding the hypothalamus was terra incognita. It is for this reason that Evgenii Vladimirovich Naumenko's monograph ac quires its special importance for the neurophysiologist, for its author has striven, by the use of experimental methods, to ascertain in detail the nature of influences which for a long time were in terpreted as the general dogmas of an abstract "nervism.

Clinical Neuroendocrinology

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Publisher : Cambridge University Press
ISBN 13 : 1316645193
Total Pages : 207 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Clinical Neuroendocrinology by : Michael Wilkinson

Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Gynecology

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Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology

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Publisher : Frontiers Media SA
ISBN 13 : 2889452328
Total Pages : 421 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology by : Nicole Gallo-Payet

Download or read book ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology written by Nicole Gallo-Payet and published by Frontiers Media SA. This book was released on 2017-07-27 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.

Pituitary-adrenal Function

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Author :
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.:/5 (38 download)

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Book Synopsis Pituitary-adrenal Function by : American Association for the Advancement of Science. Section on Medical Sciences

Download or read book Pituitary-adrenal Function written by American Association for the Advancement of Science. Section on Medical Sciences and published by . This book was released on 1951 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anxiety Disorders

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Publisher : Oxford University Press
ISBN 13 : 0199395144
Total Pages : 529 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Anxiety Disorders by : Kerry Ressler

Download or read book Anxiety Disorders written by Kerry Ressler and published by Oxford University Press. This book was released on 2015-04-15 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anxiety affects millions, manifesting as generalized anxiety disorder (GAD), obsessive compulsive disorder, panic disorder, phobias, post-traumatic-stress disorder (PTSD), and social anxiety disorder. Not only are anxiety disorders common, but they are also crippling, frequently co-occurring and predict high risk for depressive disorders. Shared mechanisms may explain the overlapping features of many anxiety disorders and account for associations with other highly-impairing conditions, such as major depression and substance use. Beyond risk for specific disorders, anxiety also predicts a number of other adverse outcomes, including suicidal behavior, medical problems, social, and economic difficulties. Conversely, disorder-specific mechanisms may also exist and explain the unique features of each syndrome. Thus, it is important to understand both shared and specific aspects of anxiety. The Primer on Anxiety Disorders provides early-stage practitioners and trainees, as well as seasoned clinicians and researchers, with need-to-know knowledge on diagnosis and treatment. Clinical cases are used throughout the book to enhance understanding of and illustrate specific disorders, comorbid conditions and clinical issues. To facilitate an integrative approach, content allows clinicians to understand patient characteristics and tailor interventions. The integrated approach of each chapter includes recent research on genetics and neuroscience to understand the mechanisms of anxiety disorders, focusing on the forthcoming new nosology in DSM-5. Chapters further integrate innovative advances in clinical research providing research on a range of discoveries regarding biomarkers of illness, biological predictors of treatments and the effect of treatment on neurocircuitry.

The Adrenal Cortex

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Publisher :
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Adrenal Cortex by : Albert B. Eisenstein

Download or read book The Adrenal Cortex written by Albert B. Eisenstein and published by . This book was released on 1967 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Overcoming Adrenal Fatigue

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Publisher : New Harbinger Publications
ISBN 13 : 1572249536
Total Pages : 162 pages
Book Rating : 4.5/5 (722 download)

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Book Synopsis Overcoming Adrenal Fatigue by : Kathryn Simpson

Download or read book Overcoming Adrenal Fatigue written by Kathryn Simpson and published by New Harbinger Publications. This book was released on 2011-05-01 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your adrenal glands play a key role in helping you control stress and maintain energy throughout the day. When these small but important glands malfunction, you may start to notice the telltale signs of adrenal fatigue. Decreased energy, weight gain, mood changes, inability to handle stress, and a weakened immune system are just a few of the symptoms of adrenal imbalance. It can slow you down, interfere with your overall sense of wellness, and even make you feel depressed. If you suspect that adrenal imbalance is causing symptoms for you, this book will help you figure out what's going wrong and partner with your health care provider to find solutions. In Overcoming Adrenal Fatigue, you'll find clear self-evaluations and treatment guidelines that will empower you to take charge of your adrenal health through nutrition, vitamins, herbs, bioidentical adrenal hormone supplementation, and self-care practices. This complete guide to optimizing adrenal health will give you the tools you'll need to get your symptoms under control and regain the energy to enjoy your active lifestyle. The complete program in this workbook will help you: Rebuild fatigued adrenals with balancing herbs and supplements Eat for all-day energy and improved concentration Practice mindfulness and relaxation techniques to reduce stress Learn about medications that can help

Functional Somatic Symptoms in Children and Adolescents

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Publisher : Springer Nature
ISBN 13 : 303046184X
Total Pages : 397 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Functional Somatic Symptoms in Children and Adolescents by : Kasia Kozlowska

Download or read book Functional Somatic Symptoms in Children and Adolescents written by Kasia Kozlowska and published by Springer Nature. This book was released on 2020-09-30 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.

Glucocorticoid Action

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Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Glucocorticoid Action by : Tomoshige Kino

Download or read book Glucocorticoid Action written by Tomoshige Kino and published by . This book was released on 2004 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glucocorticoids regulate multiple metabolic and developmental processes and play a vital role in the maintenance of basal and stress-related homeostasis. For the last 50 years, pharmacologic doses of glucocorticoids have been used in the treatment of inflammatory, autoimmune, and lymphoproliferative diseases and in the prevention of allograft rejection, while substitution doses have been employed in the management of adrenocortical insufficiency. aspects of glucocorticoid action, in particular, (i) the impact of maternal and early life stress on stress-related gene regulation in the offspring; (ii) the importance of glucocorticoids and their receptors; (iii) further understanding of the mechanisms of GR action, including its effect on chromatin modulation, its interaction with coactivators and corepressors, and the genetic dissection of GR function in mice; (iv) The interaction of hGR with other transcription factors, such as NF-kappa-B, p53, transforming growth factor beta (TGF-beta) and the chicken ovalbumin upstream promoter transcription factor II (COUP-TFII); recycling, ubiquitination and degradation of the receptor, actions of the GR-beta isoform, a novel synthetic nonsteroidal target gene-specific agonist, the importance of target tissue activity of 11-beta-hydroxysteroid dehydrogenase type 1 in glucocorticoid action in health and disease, the interaction of the receptor with the nutrient carnitine, the anthrax products protective antigen (PA) and lethal factor (LF), and the human immunodeficiency virus type-1 (HIV-1)-encoded molecules Vpr and Tat; (vi) an update on the effects of glucocorticoids on the immune system; and (vii) the clinical implications of glucocorticoid action, including glucocorticoid resistance/hypersensitivity, familial and sporadic glucocorticoid resistance, and the effects of stress and depression.

The Pituitary Gland and Adrenal Glands

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Author :
Publisher :
ISBN 13 : 9781536176056
Total Pages : 222 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis The Pituitary Gland and Adrenal Glands by : Noemi Barta

Download or read book The Pituitary Gland and Adrenal Glands written by Noemi Barta and published by . This book was released on 2020 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Pituitary Gland and Adrenal Glands: New Research, the authors first discuss pituicytomas, rare primary glial neoplasms that arise in the neurohypophysis (or posterior portion) of the pituitary gland. They typically present with signs and symptoms of a slow growing, non-hormonally active mass of the sellar and suprasellar region, compressing adjacent structures.Following this, the clinical and pathologic features of spindle cell oncocytomas are discussed. Spindle cell oncocytomas are rare tumors, accounting for less than 0.5% of sellar masses. Tumors typically present in adults and most commonly manifest with visual disturbances and pituitary hypofunction.Additionally, the authors review the clinical and pathological features of gangliocytomas, rare benign tumors of the neuroaxis. They are most commonly seen in children and young adults, and most often arise in the cerebellum as part of Cowden's disease, or in the sellar region.The clinicopathologic features of granular tumors, rare neoplasms that most commonly arise in the neurohypophysis or posterior portion of the pituitary gland, are also discussed.This compilation goes on to examine the adrenal glands, paired structures located superior to the kidneys in the retroperitoneal space. Mineralocorticoids, glucocorticoids and adrenal androgens are synthesized respectively in the zona glomerulosa, zona fasciculatis and zona reticularis that make up the cortex, while the inner adrenal medulla produces the catecholamines and peptides.The risk of developing adrenal insufficiency among glucocorticoid users is assessed, and risk factors are identified. Glucocorticoids are widely used for the treatment of various inflammatory conditions and malignancies, as well as after organ transplantation.The closing study explores hypothalamic-pituitary-adrenal axis activation, a potent and complex response to heat stress in domestic livestock. The hypothalamic-pituitary-adrenal axis is activated during stress, which leads to the secretion of cortisol and aldosterone from the adrenal gland.

Encyclopedia of Behavioral Medicine

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Author :
Publisher :
ISBN 13 : 9781461464396
Total Pages : pages
Book Rating : 4.4/5 (643 download)

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Book Synopsis Encyclopedia of Behavioral Medicine by : Marc D. Gellman

Download or read book Encyclopedia of Behavioral Medicine written by Marc D. Gellman and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Case-Based Guide to Clinical Endocrinology

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Author :
Publisher : Springer Nature
ISBN 13 : 303084367X
Total Pages : 528 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis A Case-Based Guide to Clinical Endocrinology by : Terry F. Davies

Download or read book A Case-Based Guide to Clinical Endocrinology written by Terry F. Davies and published by Springer Nature. This book was released on 2022-01-04 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections. With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.

Foundations of Neuroscience

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Foundations of Neuroscience by : Casey Henley

Download or read book Foundations of Neuroscience written by Casey Henley and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endoscopic Endonasal Transsphenoidal Surgery

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Publisher : Springer Science & Business Media
ISBN 13 : 3709160847
Total Pages : 228 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Endoscopic Endonasal Transsphenoidal Surgery by : Enrico de Divitiis

Download or read book Endoscopic Endonasal Transsphenoidal Surgery written by Enrico de Divitiis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, surgical management provides the definitive treatment of choice for most pituitary adenomas, craniopharyngiomas and meningiomas of the sellar region. The elegant minimally invasive transnasal endoscopic approach to the sella turcica and the anterior skull base has added a new dimension of versatility to pituitary surgery and can be adapted to many lesions in the region. In this multi-author book with numerous color illustrations the main aspects of the endonasal endoscopic approach to the skull base are presented, starting with a clear description of the endoscopic anatomy, the panoramic view afforded by the endoscope and the development of effective instruments and adjuncts. After the diagnostic studies, the strictly surgical features are considered in detail. The standard technique is described and particular aspects are treated, including the new extended approaches to the cavernous sinus, spheno-ethmoid planum and clival regions.