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Physiological Role Of Nitric Oxide In The Regulation Of Renal Hemodynamics Sodium Excretion And Blood Pressure In Healthy Humans
Download Physiological Role Of Nitric Oxide In The Regulation Of Renal Hemodynamics Sodium Excretion And Blood Pressure In Healthy Humans full books in PDF, epub, and Kindle. Read online Physiological Role Of Nitric Oxide In The Regulation Of Renal Hemodynamics Sodium Excretion And Blood Pressure In Healthy Humans ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Book Synopsis Neural Control of Renal Function by : Ulla Kopp
Download or read book Neural Control of Renal Function written by Ulla Kopp and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References
Book Synopsis Nitric Oxide and the Cardiovascular System by : Joseph Loscalzo
Download or read book Nitric Oxide and the Cardiovascular System written by Joseph Loscalzo and published by Springer Science & Business Media. This book was released on 2000-03-29 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinical and experimental investigators comprehensively review the chemistry, biochemistry, molecular biology, physiology, and pathophysiology of nitric oxide in the cardiovascular systems. These experts particularly illuminate nitric oxide biology, its cardiovascular pathophysiology, and its role in cardiovascular therapeutics. Topics also included are the development of nitric oxide donors for the treatment of myocardial ischemia and thrombosis, the development of gene therapeutic restoration of endothelial function in atherosclerosis, and the application of nitric oxide biology to investigative arenas in cardiovascular medicine. With its balanced presentation of basic and clinically relevant information, Nitric Oxide and the Cardiovascular System provides a comprehensive, authoritative guide for all those cardiovascular biologists, cardiologists, physiologists, and cardiovascular surgeons engaged in today's clinical or experimental research.
Book Synopsis The Renal System by : Michael John Field
Download or read book The Renal System written by Michael John Field and published by Churchill Livingstone. This book was released on 2010 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an integrated textbook on the renal system, covering the anatomy, physiology and biochemistry of the system, all presented in a clinically relevant context appropriate for the first two years of the medical student course. One of the seven volumes in the Systems of the Body series. Concise text covers the core anatomy, physiology and biochemistry in an integrated manner as required by system- and problem-based medical courses. The basic science is presented in the clinical context in a way appropriate for the early part of the medical course. There is a linked website providing self-assessment material ideal for examination preparation.
Book Synopsis The Kidney and Hypertension by : GEORGE L BAKRIS
Download or read book The Kidney and Hypertension written by GEORGE L BAKRIS and published by CRC Press. This book was released on 2003-11-28 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is common in patients with kidney disease for a number of reasons, including retention, inappropriate action by the renin-angiotensin system, and overactivity of the sympathetic nervous system. Of all causes of hypertension, renal artery stenosis (narrowing) has attracted considerable attention, because it was once thought to be a rare cause of hypertension, but is now known to be the most common cause of secondary hypertension. In The Kidney and Hypertension, George Bakris and a host of international contributors examine all aspects of hypertension in the renal patient. A reference book covering specific and common topics in the area of kidney disease and hypertension, it is an essential guide to the effective management of the renovascular patient. It covers everything from how to properly measure blood pressure to the assessment and treatment of elevated blood pressure in high-risk groups such as dialysis patients and pregnant women. Kidney and Hypertension also thoroughly discusses reducing cardiovascular risk in people with kidney disease due to its role as a leading cause of death among kidney patients. Additionally, there is a chapter on diabetes and its role as a common cause of kidney failure. As an introduction to basic concepts in the treatment of hypertension, Dr. Bakris's book will serve as an excellent reference to nephrologists, cardiologists, and cardiovascular surgeons in their efforts to reduce the risks of advanced kidney disease and cardiovascular disease.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309488346 Total Pages :595 pages Book Rating :4.3/5 (94 download)
Book Synopsis Dietary Reference Intakes for Sodium and Potassium by : National Academies of Sciences, Engineering, and Medicine
Download or read book Dietary Reference Intakes for Sodium and Potassium written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-08-26 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: As essential nutrients, sodium and potassium contribute to the fundamentals of physiology and pathology of human health and disease. In clinical settings, these are two important blood electrolytes, are frequently measured and influence care decisions. Yet, blood electrolyte concentrations are usually not influenced by dietary intake, as kidney and hormone systems carefully regulate blood values. Over the years, increasing evidence suggests that sodium and potassium intake patterns of children and adults influence long-term population health mostly through complex relationships among dietary intake, blood pressure and cardiovascular health. The public health importance of understanding these relationships, based upon the best available evidence and establishing recommendations to support the development of population clinical practice guidelines and medical care of patients is clear. This report reviews evidence on the relationship between sodium and potassium intakes and indicators of adequacy, toxicity, and chronic disease. It updates the Dietary Reference Intakes (DRIs) using an expanded DRI model that includes consideration of chronic disease endpoints, and outlines research gaps to address the uncertainties identified in the process of deriving the reference values and evaluating public health implications.
Book Synopsis Elsevier's Integrated Physiology E-Book by : Robert G. Carroll
Download or read book Elsevier's Integrated Physiology E-Book written by Robert G. Carroll and published by Elsevier Health Sciences. This book was released on 2006-12-04 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each title in the new Integrated series focuses on the core knowledge in a specific basic science discipline, while linking that information to related concepts from other disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Bonus STUDENT CONSULT access - included with the text - allows you to conveniently access the book's content online · clip content to your handheld device · link to content in other STUDENT CONSULT titles · and more! These concise and user-friendly references provide crucial guidance for the early years of medical training, as well as for exam preparation. - Includes case-based questions at the end of each chapter - Features a colour-coded format to facilitate quick reference and promote effective retention - Offers access to STUDENT CONSULT! At www.studentconsult.com, you'll find the complete text and illustrations of the book online, fully searchable · "Integration Links" to bonus content in other STUDENT CONSULT titles · content clipping for handheld devices · an interactive community center with a wealth of additional resources · and much more!
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolic Disorders and Critically Ill Patients by : Carole Ichai
Download or read book Metabolic Disorders and Critically Ill Patients written by Carole Ichai and published by Springer. This book was released on 2017-12-30 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the "milieu intérieur" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Today, the intensivit can’t ignore these disorders when selecting the most appropriate treatment for an illness. Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing the physician to understand, diagnose and treat these metabolic disorders. Water, electrolyte, acid-base, glycemic and endocrinologic problems, as well as metabolic abnormalities observed in renal, cerebral and hepatic failure are presented in different chapters. The last part of the book is devoted to modern nutritional concepts, the consequences of energy modifications, mitochondrial dysfunction, hypothermia, oxidative stress and ischemia reperfusion, which open the way for new therapies.
Book Synopsis The Athletic Horse by : David R. Hodgson
Download or read book The Athletic Horse written by David R. Hodgson and published by Elsevier Health Sciences. This book was released on 2013-06-07 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: - NEW full-color photographs depict external clinical signs, allowing more accurate clinical recognition. - NEW and improved imaging techniques maximize your ability to assess equine performance. - UPDATED drug information is presented as it applies to treatment and to new regulations for drug use in the equine athlete. - NEW advances in methods of transporting equine athletes ensure that the amount of stress on the athlete is kept to a minimum. - NEW rehabilitation techniques help to prepare the equine athlete for a return to the job. - Two NEW authors, Dr. Catherine McGowan and Dr. Kenneth McKeever, are highly recognized experts in the field.
Book Synopsis Seldin and Giebisch's The Kidney by : Robert J. Alpern
Download or read book Seldin and Giebisch's The Kidney written by Robert J. Alpern and published by Elsevier. This book was released on 2007-10-10 with total page 2922 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information.* Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.* Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.* Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.
Book Synopsis PanVascular Medicine by : Peter Lanzer
Download or read book PanVascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2015-03-30 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.
Download or read book Anesthesia Secrets written by James Duke and published by Elsevier Health Sciences. This book was released on 2011-01-01 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get quick answers to the most important clinical questions with Duke's Anesthesia Secrets, 5th Edition! Authors James Duke, MD and Brian M. Keech, MD present this easy-to-read, bestselling resource that uses the popular and trusted Secrets Series® Q&A format. It provides rapid access to the practical, "in-the-trenches" know-how you need to succeed - both in practice and on board and recertification exams. Zero in on key information with bulleted lists, tables, mnemonics, illustrations, practical tips from the authors, and "Key Points" boxes that provide a concise overview of important board-relevant content. Review essential material efficiently with the "Top 100 Secrets in Anesthesiology" - perfect for last-minute study or self-assessment. Get the evidence-based guidance you need to provide optimal care for your patients - ideal for medical students, residents, fellows, and practitioners. Apply all the latest advances in techniques, technology, and pharmacology, and explore effective solutions to a full range of clinical issues in anesthesiology. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and tables from the book on a variety of devices.
Download or read book Research Awards Index written by and published by . This book was released on with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Comprehensive Human Physiology by : Rainer Greger
Download or read book Comprehensive Human Physiology written by Rainer Greger and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 2478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.
Book Synopsis Encyclopedia of Endocrine Diseases by :
Download or read book Encyclopedia of Endocrine Diseases written by and published by Academic Press. This book was released on 2018-09-12 with total page 4225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Endocrine Diseases, Second Edition, Five Volume Set comprehensively reviews the extensive spectrum of diseases and disorders that can occur within the endocrine system. It serves as a useful and comprehensive source of information spanning the many and varied aspects of the endocrine end metabolic system. Students will find a concise description of the physiology and pathophysiology of endocrine and metabolic functions, as well as their diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters explore the latest advances and hot topics that have emerged in recent years, such as the molecular basis of endocrine and metabolic diseases (mutations, epigenetics, signaling), the pathogenesis and therapy of common endocrine diseases (e.g. diabetes and endocrine malignancies), new technologies in endocrine research, new methods of treatment, and endocrine toxicology/disruptors. Covers all aspects of endocrinology and metabolism Incorporates perspectives from experts working within the domains of biomedicine (e.g. physiology, pharmacology and toxicology, immunology, genetics) and clinical sciences to provide readers with reputable, multi-disciplinary content from domain experts Provides a ‘one-stop’ resource for access to information as written by world-leading scholars in the field, with easy cross-referencing of related articles to promote understanding and further research
Book Synopsis The Diabetic Kidney by : Pedro Cortes
Download or read book The Diabetic Kidney written by Pedro Cortes and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
