Pharmacological Effects Of Ethanol On The Nervous System

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Pharmacological Effects of Ethanol on the Nervous System

Author : Richard A. Deitrich
Publisher : CRC Press
ISBN 13 : 9780849383892
Total Pages : 482 pages
Book Rating : 4.3/5 (838 download)

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Book Synopsis Pharmacological Effects of Ethanol on the Nervous System by : Richard A. Deitrich

Download or read book Pharmacological Effects of Ethanol on the Nervous System written by Richard A. Deitrich and published by CRC Press. This book was released on 1995-12-21 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.

The Biology of Alcoholism

Author : Henri Begleiter
Publisher : Springer Science & Business Media
ISBN 13 : 1461335183
Total Pages : 635 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis The Biology of Alcoholism by : Henri Begleiter

Download or read book The Biology of Alcoholism written by Henri Begleiter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: The previous volume, The Pathogenesis of Alcoholism: Psychosocial Factors, attempted to describe the interaction of biological, psychological, and social factors that lead to the initiation and perpetuation of alcoholism. The preface to that volume presented our particular view of the bio-. psycho-social interaction as a progressive process in which earlier developments produce new pathogenetic mechanisms, which in turn lead to still other cyclical feedback activities. Although influences from each of the three phenomenologic levels are at work during each stage of the clinical course, it would appear that social factors are most significant in the early phase, psychological factors at the intermediate level, and biological ones toward the end. These differences are only relative, however, for influences of all three types surely are operative during all stages of the syndrome. This appears to be particularly true for the biological parameters of activity. Don Goodwin (1976), who has supplied much of the data that support the role of hereditary factors in alcoholism, is wont to say that all living behavior is biological-by definition. The operational evidence for this is perhaps more evident in alcoholism than in other syndromes. For example, the general social indifference of many Asians to alcohol may reflect the presence of an atypical isoenzyme of alcohol dehydrogenase rather than some independently derived cultural norm.

The Pharmacology of Alcohol and Alcohol Dependence

Author : Henri Begleiter
Publisher : Oxford University Press, USA
ISBN 13 : 9780195100945
Total Pages : 544 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis The Pharmacology of Alcohol and Alcohol Dependence by : Henri Begleiter

Download or read book The Pharmacology of Alcohol and Alcohol Dependence written by Henri Begleiter and published by Oxford University Press, USA. This book was released on 1996 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.

Alcohol and the Nervous System

Author : Edith V. Sullivan
Publisher : Elsevier
ISBN 13 : 0444626220
Total Pages : 704 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Alcohol and the Nervous System by : Edith V. Sullivan

Download or read book Alcohol and the Nervous System written by Edith V. Sullivan and published by Elsevier. This book was released on 2014-10-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Animal Models of Cognitive Impairment

Author : Edward D. Levin
Publisher : CRC Press
ISBN 13 : 1420004336
Total Pages : 400 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Animal Models of Cognitive Impairment by : Edward D. Levin

Download or read book Animal Models of Cognitive Impairment written by Edward D. Levin and published by CRC Press. This book was released on 2006-06-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications. The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer’s, schizophrenia, and ADHD. Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.

Neurobiology of Alcohol and the Brain

Author : Ashok K. Singh
Publisher : Academic Press
ISBN 13 : 0128196807
Total Pages : 364 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neurobiology of Alcohol and the Brain by : Ashok K. Singh

Download or read book Neurobiology of Alcohol and the Brain written by Ashok K. Singh and published by Academic Press. This book was released on 2020-10-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the 2018 National Survey on Drug Use and Health, 14.4 million adults aged 18 and older had alcohol use disorder (AUD). Mixing alcohol with other drugs such as opioids or cocaine has become an emerging trend, exacerbating public health concerns and may synergistically augment the seriousness of the adverse effects such as withdrawal symptoms, cardiovascular disorders, liver damage, reproductive abnormalities, and behavioral abnormalities. Despite the seriousness of the situation, possible mechanisms underlying the addiction and the withdrawal symptoms is not yet understood. This has been one of the key hindrances in developing effective treatment. Neurobiology of Alcohol and the Brain addresses the addiction-related problems reviewing both the mechanisms and withdrawal system with alcohol addiction. First, the book discusses the mechanisms of the rewarding and aversive effects, including addiction and the withdrawal symptoms of alcohol drinking. Next, alcohol's interaction with other drugs and ensuing adverse consequences is discussed including current and novel treatments against alcoholism. This is followed by a closer look at mental health and alcohol use disorder comorbidity. Lastly, the reader is provided with examples of an experimental study that describes possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Neurobiology of Alcohol and the Brain will unlock the mechanistic diversities of alcoholism helping to facilitate future developments of new, personalized treatment options for patients suffering from alcohol addiction. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Alcohol, Nutrition And the Nervous System

Author : Simone Parvez
Publisher : VSP
ISBN 13 : 9789067640503
Total Pages : 350 pages
Book Rating : 4.6/5 (45 download)

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Book Synopsis Alcohol, Nutrition And the Nervous System by : Simone Parvez

Download or read book Alcohol, Nutrition And the Nervous System written by Simone Parvez and published by VSP. This book was released on 1985-12 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Neuropharmacology of Alcohol

Author : Kathleen A. Grant
Publisher : Springer
ISBN 13 : 3319965239
Total Pages : 625 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis The Neuropharmacology of Alcohol by : Kathleen A. Grant

Download or read book The Neuropharmacology of Alcohol written by Kathleen A. Grant and published by Springer. This book was released on 2019-03-27 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.

Neuropharmacology of Ethanol

Author : KOOB
Publisher : Springer Science & Business Media
ISBN 13 : 1475713053
Total Pages : 279 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Neuropharmacology of Ethanol by : KOOB

Download or read book Neuropharmacology of Ethanol written by KOOB and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurobiology of Alcohol Dependence

Author : Antonio Noronha
Publisher : Elsevier
ISBN 13 : 0124071554
Total Pages : 566 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Neurobiology of Alcohol Dependence by : Antonio Noronha

Download or read book Neurobiology of Alcohol Dependence written by Antonio Noronha and published by Elsevier. This book was released on 2014-05-02 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available

Brain Disorders in Critical Illness

Author : Robert D. Stevens
Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

Addictive Substances and Neurological Disease

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128092963
Total Pages : 414 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Addictive Substances and Neurological Disease by : Ronald Ross Watson

Download or read book Addictive Substances and Neurological Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2017-02-18 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances

Edwards' Treatment of Drinking Problems

Author : Keith Humphreys
Publisher : Cambridge University Press
ISBN 13 : 1107519527
Total Pages : 279 pages
Book Rating : 4.1/5 (75 download)

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Book Synopsis Edwards' Treatment of Drinking Problems by : Keith Humphreys

Download or read book Edwards' Treatment of Drinking Problems written by Keith Humphreys and published by Cambridge University Press. This book was released on 2016-04-28 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art, accessible reviews of the science of alcohol treatment and guidance for the management of clinical situations.

Addiction

Author : Chris Chandler
Publisher : SAGE
ISBN 13 : 1526465493
Total Pages : 398 pages
Book Rating : 4.5/5 (264 download)

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Book Synopsis Addiction by : Chris Chandler

Download or read book Addiction written by Chris Chandler and published by SAGE. This book was released on 2018-10-29 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addiction: A biopsychosocial perspective provides students with an evidence-based approach to addiction whilst covering a broad range of topics, critical perspectives and influential theories in addiction. With chapters discussing key theories, psychological, biological and societal aspects of addiction, this is a highly accessible and essential resource for students and researchers that: Offers an evidence-based discussion of addiction Addresses the neuroscience and psychology of addiction Provides a critical account of the science and research in addiction Includes chapter overviews and summaries, learning aims and case studies to help students in their study

Alcohol and Neurobiology

Author : Ronald Ross Watson
Publisher : CRC Press
ISBN 13 : 9780849379369
Total Pages : 340 pages
Book Rating : 4.3/5 (793 download)

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Book Synopsis Alcohol and Neurobiology by : Ronald Ross Watson

Download or read book Alcohol and Neurobiology written by Ronald Ross Watson and published by CRC Press. This book was released on 1992-06-24 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public attention and research efforts are being driven by an ever- increasing understanding of the problems and magnitude of alcohol abuse, particularly its neurological consequences. Two out of three high school students report that they used alcohol during the previous month. This continuing source of potential abusers, plus 10 million alcohol-abusing adults, along with the several million abusers of other drugs, costs the people of the U.S. more than $200 billion in lost wages, health care, theft, and shortened life span. An intimate, detailed knowledge of the effects of alcohol on the biochemical reactions and neurological changes is critical in preventing or treating abuse. We must study the mechanisms of ethanol's effects on the neurological system at a cellular and systematic level to understand its actions. These include modifications of hormonal regulation and production with major functional consequences. The progress of research over the past decade is encouraging as we begin to summarize and evaluate in detail advances in understanding changes in the biochemistry and physiology caused by ethanol. This information will assist the researcher, clinician, and student in comprehending the complex changes caused by direct and indirect effects of single drugs at the cellular level.

Animal Models for Medications Screening to Treat Addiction

Author : Richard L Bell
Publisher : Academic Press
ISBN 13 : 0128040580
Total Pages : 562 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Animal Models for Medications Screening to Treat Addiction by : Richard L Bell

Download or read book Animal Models for Medications Screening to Treat Addiction written by Richard L Bell and published by Academic Press. This book was released on 2016-04-04 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for Medications Screening to Treat Addiction, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Brings together information on the current state of medication development for drug addiction using animal models Contains comprehensive descriptions of various models associated with many forms of drug addiction Adds new information for translational research in the field of drug addiction

The Pharmacology of Alcohol and Drugs of Abuse and Addiction

Author : Norman S. Miller
Publisher : Springer Science & Business Media
ISBN 13 : 1461230446
Total Pages : 359 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The Pharmacology of Alcohol and Drugs of Abuse and Addiction by : Norman S. Miller

Download or read book The Pharmacology of Alcohol and Drugs of Abuse and Addiction written by Norman S. Miller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is intended for clinicians, researchers, residents, and students. The range is wide and the depth considerable for all the topics covered in the treatment of this timely and relevant subject. This book may serve equally well as a general introduction and a scholarly reference. Ultimately, it is designed to serve those patients suffering from abuse of and addiction to drugs and alcohol. The content and organization of the book flow from general concepts of abuse and addiction to specific details of the pharmacology of alcohol and drugs. Special chapters on topics not found in most other books, such as pharmacology of drug-drug interactions, abstinence, and prevention, are included. This book is written especially for the clinician interested in the pharma cology of alcohol and drugs of abuse and addiction. The pharmacology is integrated into a conceptual approach to diagnosis and treatment of alcohol and drug abuse and addiction. The form and style are didactic, critical as well as straightforward in presentation. Literature references from recent clinical research and basic research provide the foundation for the chapters throughout the book. Be cause the book is written by a clinician-researcher, the information is readily adaptable to clinical problems and research ideas. I would like to express my deep appreciation to Susan Newsom and Darlene Tucci for their invaluable technical assistance. Norman S. Miller vii Contents Preface ....................................................... vii CHAPTER 1 Introduction to the Pharmacological Effects of Alcohol and Drugs and Addiction on the Brain and Behavior .... . . . . . . . . . . . . . . . . . .. . . 1 . . . . . .