Pharmacokinetics And Pharmacodynamics Of Novel Drug Delivery Systems From Basic Concepts To Applications

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Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: from Basic Concepts to Applications

Author : Sankalp A Gharat
Publisher : Springer
ISBN 13 : 9789819978571
Total Pages : 0 pages
Book Rating : 4.9/5 (785 download)

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Book Synopsis Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: from Basic Concepts to Applications by : Sankalp A Gharat

Download or read book Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: from Basic Concepts to Applications written by Sankalp A Gharat and published by Springer. This book was released on 2024-06-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book delves into the intricate realm of pharmacokinetics and pharmacodynamics as they apply to modern advancements in drug delivery systems. It offers a comprehensive exploration of novel drug delivery methods, with a particular focus on nanoparticles and nanocarriers. The absorption, distribution, metabolism, and excretion processes of nanoparticles are extensively examined. It also covers various evaluation models, spanning from preclinical to clinical, aimed at assessing the effectiveness and safety of nanoparticles in drug delivery. It also covers the integration of Artificial Intelligence and Machine Learning in pharmacokinetics and pharmacodynamics, showcasing how these cutting-edge approaches can enhance our understanding of drug behavior and optimize therapeutic outcomes. It serves as a comprehensive guide, highlighting the fusion of traditional pharmacological concepts with contemporary drug delivery systems and innovative technologies, all in the pursuit of refining medical treatments and patient care and is a valuable resource for academicians, researchers, and pharmacologists.

Drug Delivery

Author : Binghe Wang
Publisher : John Wiley & Sons
ISBN 13 : 1118833368
Total Pages : 740 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Drug Delivery by : Binghe Wang

Download or read book Drug Delivery written by Binghe Wang and published by John Wiley & Sons. This book was released on 2016-04-18 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

Author : Jayvadan K. Patel
Publisher : Springer Nature
ISBN 13 : 303083395X
Total Pages : 437 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems by : Jayvadan K. Patel

Download or read book Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems written by Jayvadan K. Patel and published by Springer Nature. This book was released on 2022-03-07 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Novel Drug Delivery Systems, Second Edition,

Author : Yie Chien
Publisher : CRC Press
ISBN 13 : 9780824785208
Total Pages : 816 pages
Book Rating : 4.7/5 (852 download)

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Book Synopsis Novel Drug Delivery Systems, Second Edition, by : Yie Chien

Download or read book Novel Drug Delivery Systems, Second Edition, written by Yie Chien and published by CRC Press. This book was released on 1991-10-31 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the science, technology, and regulation of rate-controlled administration of therapeutic agents, with coverage of the basic concepts, fundamental principles, biomedical rationales, and potential applications. This revised and updated edition (first in 1982) incorporates

Advanced Drug Delivery

Author : Ashim Mitra
Publisher : John Wiley & Sons
ISBN 13 : 1118662849
Total Pages : 844 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Advanced Drug Delivery by : Ashim Mitra

Download or read book Advanced Drug Delivery written by Ashim Mitra and published by John Wiley & Sons. This book was released on 2013-08-26 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Novel Drug Delivery and Its Therapeutic Application

Author : L. F. Prescott
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Novel Drug Delivery and Its Therapeutic Application by : L. F. Prescott

Download or read book Novel Drug Delivery and Its Therapeutic Application written by L. F. Prescott and published by John Wiley & Sons. This book was released on 1989 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: International research specialists discuss their work with pharmaceuticals in this text, focusing on the mechanisms and assessment of drug absorption and delivery. The book also explores the ways in which a drug should be administered to provide self-regulating and programmed delivery.

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Author : Ryan F. Donnelly
Publisher : John Wiley & Sons
ISBN 13 : 1118734491
Total Pages : 296 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by : Ryan F. Donnelly

Download or read book Novel Delivery Systems for Transdermal and Intradermal Drug Delivery written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2015-09-21 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Drug Delivery Systems

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
ISBN 13 : 1588298914
Total Pages : 255 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Drug Delivery Systems by : Kewal K. Jain

Download or read book Drug Delivery Systems written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2008-03-07 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.

Drug Delivery

Author : Binghe Wang
Publisher : John Wiley & Sons
ISBN 13 : 0471475718
Total Pages : 463 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Drug Delivery by : Binghe Wang

Download or read book Drug Delivery written by Binghe Wang and published by John Wiley & Sons. This book was released on 2005-04-29 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Bringing together contributions by leading international experts, Drug Delivery covers the entire field in a systematic but concise way. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination-including overviews, timely examples, and extensive references-of a host of specific subjects, including: * Receptor-mediated drug delivery * Prodrug delivery approaches * Oral protein and peptide drug delivery * Gene therapy and gene delivery * Ultrasound-mediated drug delivery * Polycationic peptides and proteins in drug delivery * Pulmonary drug delivery * Antibody-directed drug delivery * Efflux transporters in drug excretion * Intellectual property issues in drug delivery

Fundamentals and Applications of Controlled Release Drug Delivery

Author : Juergen Siepmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461408814
Total Pages : 593 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Fundamentals and Applications of Controlled Release Drug Delivery by : Juergen Siepmann

Download or read book Fundamentals and Applications of Controlled Release Drug Delivery written by Juergen Siepmann and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

Drug Delivery

Author : Eric P. Holowka
Publisher : Springer
ISBN 13 : 1493919989
Total Pages : 355 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Drug Delivery by : Eric P. Holowka

Download or read book Drug Delivery written by Eric P. Holowka and published by Springer. This book was released on 2014-11-22 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on “Engineering Concepts” reviews the relevant fundamental principles that guide rational design. The following section on “Materials Design” discusses how the design process applies engineering concepts for use in physiological systems. A third section on “Implementation” discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on “Clinical Applications” which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. · Provides a comprehensive description of drug delivery systems from a materials perspective · Includes a wide-ranging discussion of clinical applications of drug delivery systems · Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. · Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type

Novel Drug Delivery Systems

Author : Yie Chien
Publisher : CRC Press
ISBN 13 : 9780367402914
Total Pages : 816 pages
Book Rating : 4.4/5 (29 download)

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Book Synopsis Novel Drug Delivery Systems by : Yie Chien

Download or read book Novel Drug Delivery Systems written by Yie Chien and published by CRC Press. This book was released on 2019-08-30 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the science, technology, and regulation of rate-controlled administration of therapeutic agents, with coverage of the basic concepts, fundamental principles, biomedical rationales, and potential applications. This revised and updated edition (first in 1982) incorporates

Drug Delivery Approaches

Author : Bret Berner
Publisher : John Wiley & Sons
ISBN 13 : 1119772753
Total Pages : 466 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Drug Delivery Approaches by : Bret Berner

Download or read book Drug Delivery Approaches written by Bret Berner and published by John Wiley & Sons. This book was released on 2021-08-04 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts in the field Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes. The distinguished editors have included practical and accessible resources that address the biological and delivery approaches to pulmonary and mucosal delivery of drugs. Emergency care settings are also described, with explorations of the relationship between parenteral infusion profiles and PK/PD. The future of drug delivery is addressed via discussions of virtual experiments to elucidate mechanisms and approaches to drug delivery and personalized medicine. Readers will also benefit from the inclusion of: A thorough introduction to the utility of mathematical models in drug development and delivery An exploration of the techniques and applications of physiologically based models to drug delivery Discussions of oral delivery and pharmacokinetic models and oral site-directed delivery A review of integrated transdermal delivery and pharmacokinetics in development An examination of virtual experiment methods for integrating pharmacokinetic, pharmacodynamic, and drug delivery mechanisms Alternative endpoints to pharmacokinetics for topical delivery Perfect for researchers, industrial scientists, graduate students, and postdoctoral students in the area of pharmaceutical science and engineering, Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics will also earn a place in the libraries of formulators, pharmacokineticists, and clinical pharmacologists.

Design of Controlled Release Drug Delivery Systems

Author : Xiaoling Li
Publisher : McGraw Hill Professional
ISBN 13 : 0071588833
Total Pages : 453 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis Design of Controlled Release Drug Delivery Systems by : Xiaoling Li

Download or read book Design of Controlled Release Drug Delivery Systems written by Xiaoling Li and published by McGraw Hill Professional. This book was released on 2005-11-24 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Drug Delivery Systems

Author : Vasant V. Ranade
Publisher : CRC Press
ISBN 13 : 1420040146
Total Pages : 464 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Drug Delivery Systems by : Vasant V. Ranade

Download or read book Drug Delivery Systems written by Vasant V. Ranade and published by CRC Press. This book was released on 2003-08-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both

Basic Fundamentals of Drug Delivery

Author :
Publisher : Academic Press
ISBN 13 : 0128179104
Total Pages : 810 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Basic Fundamentals of Drug Delivery by :

Download or read book Basic Fundamentals of Drug Delivery written by and published by Academic Press. This book was released on 2018-11-30 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study

Nanomaterials for Drug Delivery and Therapy

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128166290
Total Pages : 580 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanomaterials for Drug Delivery and Therapy by : Alexandru Mihai Grumezescu

Download or read book Nanomaterials for Drug Delivery and Therapy written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-03-14 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers