Pharmacogenomics A Primer For Clinicians

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Pharmacogenomics: A Primer for Clinicians

Author : Jerika T. Lam
Publisher : McGraw Hill Professional
ISBN 13 : 1260457117
Total Pages : 186 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Pharmacogenomics: A Primer for Clinicians by : Jerika T. Lam

Download or read book Pharmacogenomics: A Primer for Clinicians written by Jerika T. Lam and published by McGraw Hill Professional. This book was released on 2020-12-22 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.

Pharmacogenomics

Author : Federico Innocenti
Publisher : Springer Science & Business Media
ISBN 13 : 1592599575
Total Pages : 215 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Pharmacogenomics by : Federico Innocenti

Download or read book Pharmacogenomics written by Federico Innocenti and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.

Clinical Precision Medicine

Author : Judy S. Crabtree
Publisher : Academic Press
ISBN 13 : 0128204028
Total Pages : 114 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Clinical Precision Medicine by : Judy S. Crabtree

Download or read book Clinical Precision Medicine written by Judy S. Crabtree and published by Academic Press. This book was released on 2019-11-15 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics Features chapter contributions from leaders in the field Consolidates fundamental concepts and current practices of precision medicine in one convenient resource

Concepts in Pharmacogenomics

Author : Martin M. Zdanowicz
Publisher : ASHP
ISBN 13 : 1585282340
Total Pages : 425 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Concepts in Pharmacogenomics by : Martin M. Zdanowicz

Download or read book Concepts in Pharmacogenomics written by Martin M. Zdanowicz and published by ASHP. This book was released on 2010 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new science of pharmacogenomics aims to understand how an individual's genetic composition affects his/her response to a specific drug or class of drugs. By studying such characteristics as drug metabolizing enzymes, drug transporter activity, and receptor sensitivity, a pharmacist is better able to prescribe the right drug the first time.If you are pharmacist, resident, or student curious about this new field, start withConcepts in Pharmacogenomics. In this practical guide, you will find an overview of the science behind pharmacogenomics, followed by detailed chapters related to its clinical application and implementation.Features include: case studies in each chapter clinical pearls illustrations of key concepts figures, diagrams, and flow charts for visual learners key points summarized.

Psychiatric Genetics

Author : Thomas G. Schulze
Publisher : Oxford University Press
ISBN 13 : 0190221976
Total Pages : 241 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Psychiatric Genetics by : Thomas G. Schulze

Download or read book Psychiatric Genetics written by Thomas G. Schulze and published by Oxford University Press. This book was released on 2018 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of take home points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning about the key concepts and recent advances in the exciting field of psychiatric genetics.

Pharmacogenomics An Introduction and Clinical Perspective

Author : Joseph S. Bertino
Publisher : McGraw Hill Professional
ISBN 13 : 0071813713
Total Pages : 288 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Pharmacogenomics An Introduction and Clinical Perspective by : Joseph S. Bertino

Download or read book Pharmacogenomics An Introduction and Clinical Perspective written by Joseph S. Bertino and published by McGraw Hill Professional. This book was released on 2012-10-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty

Pharmacogenomics

Author : Howard L. McLeod
Publisher :
ISBN 13 : 9781932658699
Total Pages : 485 pages
Book Rating : 4.6/5 (586 download)

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Book Synopsis Pharmacogenomics by : Howard L. McLeod

Download or read book Pharmacogenomics written by Howard L. McLeod and published by . This book was released on 2009-01-01 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics offers the opportunity for clinicians to dramatically improve the health outcomes of millions of patients receiving drug therapy. However, this opportunity is tempered by the challenge of learning the seemingly limitless amount of genetic information assembled during the past decade, with new knowledge developing rapidly. ACCP has developed this textbook to assist clinicians in meeting this challenge. The enhanced second edition, written by leaders in pharmacogenomics from different practice areas, disciplines, and research environments, combines the basics of pharmacogenomics with disease-specific applications to give students and practitioners a solid foundation for understanding the basic science of pharmacogenomics and the skills for integrating pharmacogenomics into daily clinical practice.

Principles of Pharmacogenetics and Pharmacogenomics

Author : Russ B. Altman
Publisher : Cambridge University Press
ISBN 13 : 1107377471
Total Pages : 283 pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis Principles of Pharmacogenetics and Pharmacogenomics by : Russ B. Altman

Download or read book Principles of Pharmacogenetics and Pharmacogenomics written by Russ B. Altman and published by Cambridge University Press. This book was released on 2012-01-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences.

Pharmacogenomics

Author : Joseph S. Bertino
Publisher :
ISBN 13 : 9786613968661
Total Pages : 274 pages
Book Rating : 4.9/5 (686 download)

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Book Synopsis Pharmacogenomics by : Joseph S. Bertino

Download or read book Pharmacogenomics written by Joseph S. Bertino and published by . This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Road from Nanomedicine to Precision Medicine

Author : Shaker A. Mousa
Publisher : CRC Press
ISBN 13 : 1000021270
Total Pages : 669 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis The Road from Nanomedicine to Precision Medicine by : Shaker A. Mousa

Download or read book The Road from Nanomedicine to Precision Medicine written by Shaker A. Mousa and published by CRC Press. This book was released on 2020-01-17 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Pharmacotherapy Casebook

Author : Terry L. Schwinghammer
Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 484 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pharmacotherapy Casebook by : Terry L. Schwinghammer

Download or read book Pharmacotherapy Casebook written by Terry L. Schwinghammer and published by McGraw-Hill Medical Publishing. This book was released on 2005 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This casebook is designed to help students develop the skills required to identify and resolve drug therapy problems through the use of patient case studies.

Basic Skills in Interpreting Laboratory Data

Author : Mary Lee
Publisher : ASHP
ISBN 13 : 1585283452
Total Pages : 1248 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Basic Skills in Interpreting Laboratory Data by : Mary Lee

Download or read book Basic Skills in Interpreting Laboratory Data written by Mary Lee and published by ASHP. This book was released on 2013-06-01 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Skills in Interpreting Laboratory Data, Fifth Edition, is the classic and most popular pharmacy laboratory text because it is the only reference on this subject written by pharmacists, for pharmacists. Students find this guide a clear and useful introduction to the fundamentals of interpreting laboratory test results. The book enhances the skills pharmacists need by providing essential information on common laboratory tests used to screen for or diagnose diseases and monitor the effectiveness and safety of treatment and disease severity. Each chapter contains learning objectives, case studies, bibliographies, and charts that summarize the causes of high and low test results. New for this edition: Updated and expanded Quick View tables in each chapter now match those in the popular quick-reference, Interpreting Laboratory Data: A Point-of-Care Guide New glossary of acronyms is right up front for a streamlined reference Normal value ranges of all tests have been standardized by an expert pathologist New and updated cases in each chapter apply your Basic Skills in clinical situations Reorganized to highlight the application of concepts by body system, and in special populations Basic Skills in Interpreting Laboratory Data offers features that will help pharmacy students not only understand and engage with the material but also will streamline the transition from classroom to practice setting. After studying with this trusted text, students and pharmacists will more effectively monitor patient therapy, evaluate test results, and improve outcomes through optimal and focused pharmacotherapy.

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Author : David F. Kisor
Publisher : Jones & Bartlett Publishers
ISBN 13 : 9781449633936
Total Pages : 204 pages
Book Rating : 4.6/5 (339 download)

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Book Synopsis Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine by : David F. Kisor

Download or read book Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine written by David F. Kisor and published by Jones & Bartlett Publishers. This book was released on 2014 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenetics, Kinetics, And Dynamics For Personalized Medicine Provides A Primer To Understand Pharmacogenetics (The Study Of Genetic Factors That Influence How A Drug Works) In The Applied Context Of Pharmacokinetics (How The Body Handles A Drug) And Pharmacodynamics (The Effects Of A Drug On The Body). This Valuable Foundation Illuminates How These Principles And Scientific Advances Can Create Optimal Individual Patient Care, That Is, "Personalized Medicine." Through Specific Drug Examples, This Resource Explores How The Genetic Constitution Of An Individual May Lead To The Need For An Altered Dose Or In Some Cases Alternative Drug Therapy. Real-World Cases Highlight The Specific Relationships Between Genetics, Drug Action, And The Body'S Response As Well As Adverse Drug Reactions, Altered Metabolism, And Drug Efficacy. Ethical Issues Concerning Pharmacogenomics And Study Design Are Also Discussed In This Concise Overview.

Psoriasis

Author : Anca Chiriac
Publisher : BoD – Books on Demand
ISBN 13 : 9535132512
Total Pages : 248 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Psoriasis by : Anca Chiriac

Download or read book Psoriasis written by Anca Chiriac and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2014, psoriasis was recognized as a serious noncommunicable disease in the World Health Assembly Resolution WHA67.9, with a great negative impact on patients' quality of life. Psoriasis is a worldwide chronic disease, affecting all ages and all races, and a serious global health problem. Psoriasis is a complex disease with still unknown etiology and no specific curative treatment. The chapters provide comprehensive and new description of some issues related to psoriasis research and for understanding of clinical correlations, genetic aspects, experimental research, and potential therapeutic interventions. The book could be a source of information for clinicians and researchers from different fields in raising awareness of the disease.

Pharmacogenomics

Author : Federico Innocenti
Publisher : Humana Press
ISBN 13 : 9781627034364
Total Pages : 359 pages
Book Rating : 4.0/5 (343 download)

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Book Synopsis Pharmacogenomics by : Federico Innocenti

Download or read book Pharmacogenomics written by Federico Innocenti and published by Humana Press. This book was released on 2013-07-04 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding an individual's genetic makeup is the key to creating personalized drugs with greater efficacy and safety, and pharmacogenomics aims to study the complex genetic basis of inter-patient variability in response to drug therapy. Based upon the success of its first edition, the second edition of Pharmacogenomics: Methods And Protocols aims to continue providing readers with high-quality content on the most innovative and commonly adopted technologies in the field of pharmacogenomics as presented by experts in the field. Broken into several sections, this detailed volume examines techniques for interrogating variation in human genes and genomes, functional assessment of genetic variation, both in vitro and in vivo, as well as tools for translation and implementation of pharmacogenetic markers. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to the respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and thoroughly updated, Pharmacogenomics: Methods And Protocols, Second Edition serves as an essential reference and an invaluable source on the latest information in this field.

Pharmacogenomics

Author : Showkat Ahmad Ganie
Publisher : Elsevier
ISBN 13 : 044315337X
Total Pages : 392 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Pharmacogenomics by : Showkat Ahmad Ganie

Download or read book Pharmacogenomics written by Showkat Ahmad Ganie and published by Elsevier. This book was released on 2023-06-13 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book. Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impacts Describes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseases Uses a consistent chapter structure to support understanding of the fundamental concepts in the area

Pharmacogenomics in Drug Discovery and Development

Author : Qing Yan
Publisher : Springer Nature
ISBN 13 : 107162573X
Total Pages : 618 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Pharmacogenomics in Drug Discovery and Development by : Qing Yan

Download or read book Pharmacogenomics in Drug Discovery and Development written by Qing Yan and published by Springer Nature. This book was released on 2022-09-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.